NO20090224L - Anti-IL-6 monoklonale antistoffer og anvendelser derav - Google Patents

Anti-IL-6 monoklonale antistoffer og anvendelser derav

Info

Publication number
NO20090224L
NO20090224L NO20090224A NO20090224A NO20090224L NO 20090224 L NO20090224 L NO 20090224L NO 20090224 A NO20090224 A NO 20090224A NO 20090224 A NO20090224 A NO 20090224A NO 20090224 L NO20090224 L NO 20090224L
Authority
NO
Norway
Prior art keywords
monoclonal antibodies
amino acid
well
region selected
regions
Prior art date
Application number
NO20090224A
Other languages
English (en)
Norwegian (no)
Inventor
Ernest S Smith
Wei Wang
Original Assignee
Vaccinex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaccinex Inc filed Critical Vaccinex Inc
Publication of NO20090224L publication Critical patent/NO20090224L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/248IL-6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
NO20090224A 2006-08-03 2009-01-15 Anti-IL-6 monoklonale antistoffer og anvendelser derav NO20090224L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83510706P 2006-08-03 2006-08-03
PCT/US2007/017337 WO2008019061A2 (en) 2006-08-03 2007-08-03 Anti-il-6 monoclonal antibodies and uses thereof

Publications (1)

Publication Number Publication Date
NO20090224L true NO20090224L (no) 2009-03-31

Family

ID=39033490

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090224A NO20090224L (no) 2006-08-03 2009-01-15 Anti-IL-6 monoklonale antistoffer og anvendelser derav

Country Status (17)

Country Link
US (1) US7919095B2 (es)
EP (1) EP2064241B1 (es)
JP (1) JP2009545319A (es)
KR (1) KR101479537B1 (es)
CN (1) CN101563365B (es)
AU (1) AU2007282023B2 (es)
BR (1) BRPI0715115A2 (es)
CA (1) CA2657763C (es)
CO (1) CO6150192A2 (es)
CR (1) CR10563A (es)
EA (1) EA200900037A1 (es)
IL (1) IL196550A0 (es)
MA (1) MA30653B1 (es)
MX (1) MX2009001110A (es)
NO (1) NO20090224L (es)
WO (1) WO2008019061A2 (es)
ZA (1) ZA200900514B (es)

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US8992920B2 (en) 2008-11-25 2015-03-31 Alderbio Holdings Llc Anti-IL-6 antibodies for the treatment of arthritis
US9212223B2 (en) 2008-11-25 2015-12-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
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Also Published As

Publication number Publication date
CN101563365A (zh) 2009-10-21
US7919095B2 (en) 2011-04-05
US20080075726A1 (en) 2008-03-27
WO2008019061A3 (en) 2008-10-09
BRPI0715115A2 (pt) 2013-06-04
KR101479537B1 (ko) 2015-01-07
EP2064241B1 (en) 2015-10-07
ZA200900514B (en) 2010-04-28
WO2008019061A2 (en) 2008-02-14
CN101563365B (zh) 2012-10-31
JP2009545319A (ja) 2009-12-24
IL196550A0 (en) 2011-08-01
MA30653B1 (fr) 2009-08-03
AU2007282023A1 (en) 2008-02-14
MX2009001110A (es) 2009-05-11
CO6150192A2 (es) 2010-04-20
EP2064241A2 (en) 2009-06-03
CA2657763A1 (en) 2008-02-14
KR20090039801A (ko) 2009-04-22
EA200900037A1 (ru) 2009-10-30
CA2657763C (en) 2016-05-31
AU2007282023B2 (en) 2012-09-13
CR10563A (es) 2009-04-14

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