NO20032708D0 - Steroidhormonprodukter og deres fremstilling - Google Patents

Steroidhormonprodukter og deres fremstilling

Info

Publication number
NO20032708D0
NO20032708D0 NO20032708A NO20032708A NO20032708D0 NO 20032708 D0 NO20032708 D0 NO 20032708D0 NO 20032708 A NO20032708 A NO 20032708A NO 20032708 A NO20032708 A NO 20032708A NO 20032708 D0 NO20032708 D0 NO 20032708D0
Authority
NO
Norway
Prior art keywords
products
hormone
excipient
steroid hormone
preparation
Prior art date
Application number
NO20032708A
Other languages
English (en)
Other versions
NO334341B1 (no
NO20032708L (no
Inventor
Thomas W Schultz
Bradley A Clark
Angela Falzone
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of NO20032708D0 publication Critical patent/NO20032708D0/no
Publication of NO20032708L publication Critical patent/NO20032708L/no
Publication of NO334341B1 publication Critical patent/NO334341B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20032708A 2000-12-14 2003-06-13 Steroidhormonprodukt og fremgangsmåte for fremstilling derav NO334341B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25566900P 2000-12-14 2000-12-14
PCT/US2001/048862 WO2002047693A2 (en) 2000-12-14 2001-12-13 Steroid hormone products comprising a stabilizing agent in non-crystalline form

Publications (3)

Publication Number Publication Date
NO20032708D0 true NO20032708D0 (no) 2003-06-13
NO20032708L NO20032708L (no) 2003-07-04
NO334341B1 NO334341B1 (no) 2014-02-10

Family

ID=22969374

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20032708A NO334341B1 (no) 2000-12-14 2003-06-13 Steroidhormonprodukt og fremgangsmåte for fremstilling derav
NO20131334A NO20131334L (no) 2000-12-14 2013-10-04 Steroidhormonprodukter og deres fremstilling

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20131334A NO20131334L (no) 2000-12-14 2013-10-04 Steroidhormonprodukter og deres fremstilling

Country Status (31)

Country Link
US (4) US7867990B2 (no)
EP (2) EP1591121B1 (no)
KR (1) KR100899032B1 (no)
CN (1) CN1290507C (no)
AT (2) ATE307591T1 (no)
AU (2) AU2742102A (no)
BG (1) BG66178B1 (no)
BR (1) BRPI0116793B8 (no)
CA (1) CA2431521E (no)
CR (1) CR7022A (no)
CY (1) CY1109404T1 (no)
CZ (1) CZ306435B6 (no)
DE (2) DE60114467T2 (no)
DK (2) DK1361881T3 (no)
EC (1) ECSP034654A (no)
EE (1) EE05358B1 (no)
ES (2) ES2327538T3 (no)
HK (2) HK1057174A1 (no)
HU (1) HU230400B1 (no)
IL (2) IL156423A0 (no)
ME (1) ME00339B (no)
MX (1) MXPA03005339A (no)
NO (2) NO334341B1 (no)
NZ (1) NZ526517A (no)
PT (1) PT1591121E (no)
RS (1) RS50414B (no)
RU (1) RU2286155C2 (no)
SK (1) SK288222B6 (no)
UA (1) UA77404C2 (no)
WO (1) WO2002047693A2 (no)
ZA (1) ZA200305342B (no)

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US8486926B2 (en) * 2006-11-17 2013-07-16 Harbor Therapeutics, Inc. Steroid tetrol solid state forms
EP2249838A4 (en) * 2008-02-05 2012-05-02 Harbor Biosciences Inc PHARMACEUTICAL FORMS IN SOLID STATE
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RU2016101363A (ru) * 2010-02-08 2018-11-21 Прэари Фармасьютикалз, Ллк Способ лечения заболеваний, связанных с глюкокортикоидной нечувствительностью
BR112014012444B1 (pt) 2011-11-23 2021-12-14 Therapeuticsmd, Inc Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher
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US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CN102793929B (zh) * 2012-09-07 2013-12-11 上海奥科达生物医药科技有限公司 一种制备稳定非晶态药物制剂的方法
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
JP2017516768A (ja) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然の併用ホルモン補充療法剤及び療法
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
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US20200129438A1 (en) * 2018-10-31 2020-04-30 Edenbridge Pharmaceuticals, LLC Finished pharmaceutical dosage form comprising a low dose/high potency active pharmaceutical ingredient and one or more excipients
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Also Published As

Publication number Publication date
EE05358B1 (et) 2010-12-15
KR100899032B1 (ko) 2009-05-21
HK1057174A1 (en) 2004-03-19
ATE307591T1 (de) 2005-11-15
WO2002047693A3 (en) 2002-11-07
DE60139087D1 (de) 2009-08-06
HUP0400646A3 (en) 2012-08-28
US20020173669A1 (en) 2002-11-21
NO334341B1 (no) 2014-02-10
BRPI0116793B8 (pt) 2021-05-25
BR0116793A (pt) 2004-01-27
PT1591121E (pt) 2009-07-20
AU2742102A (en) 2002-06-24
ES2327538T3 (es) 2009-10-30
US20110046095A1 (en) 2011-02-24
AU2002227421B2 (en) 2007-08-23
DE60114467T2 (de) 2006-07-20
EP1591121A1 (en) 2005-11-02
MXPA03005339A (es) 2004-03-26
EP1361881A2 (en) 2003-11-19
CN1290507C (zh) 2006-12-20
DE60114467D1 (de) 2005-12-01
ECSP034654A (es) 2003-07-25
CN1489468A (zh) 2004-04-14
CA2431521C (en) 2010-03-16
ZA200305342B (en) 2004-10-11
CR7022A (es) 2009-02-23
ES2253451T3 (es) 2006-06-01
EE200300229A (et) 2003-08-15
UA77404C2 (en) 2006-12-15
ATE434439T1 (de) 2009-07-15
RS50414B (sr) 2009-12-31
HU230400B1 (hu) 2016-04-28
RU2003121240A (ru) 2005-02-10
EP1361881B1 (en) 2005-10-26
BRPI0116793B1 (pt) 2015-06-23
CA2431521E (en) 2013-04-16
NO20131334L (no) 2003-07-04
CZ20031896A3 (en) 2004-03-17
CZ306435B6 (cs) 2017-01-25
ME00339B (me) 2011-05-10
NZ526517A (en) 2005-09-30
HK1083457A1 (en) 2006-07-07
CA2431521A1 (en) 2002-06-20
HUP0400646A2 (hu) 2004-06-28
EP1591121B1 (en) 2009-06-24
YU47903A (sh) 2006-08-17
CY1109404T1 (el) 2014-07-02
WO2002047693A2 (en) 2002-06-20
KR20030061856A (ko) 2003-07-22
US20110046099A1 (en) 2011-02-24
MEP48808A (en) 2011-02-10
NO20032708L (no) 2003-07-04
SK288222B6 (sk) 2014-09-04
DK1361881T3 (da) 2006-02-20
IL156423A (en) 2010-04-29
SK8802003A3 (en) 2004-04-06
US20140309204A1 (en) 2014-10-16
DK1591121T3 (da) 2009-10-05
US7867990B2 (en) 2011-01-11
BG107958A (bg) 2004-11-30
BG66178B1 (bg) 2011-11-30
RU2286155C2 (ru) 2006-10-27
IL156423A0 (en) 2004-01-04

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