CR7022A - Productos esteroides hormonales y metodos para su preparacion - Google Patents

Productos esteroides hormonales y metodos para su preparacion

Info

Publication number
CR7022A
CR7022A CR7022A CR7022A CR7022A CR 7022 A CR7022 A CR 7022A CR 7022 A CR7022 A CR 7022A CR 7022 A CR7022 A CR 7022A CR 7022 A CR7022 A CR 7022A
Authority
CR
Costa Rica
Prior art keywords
preparation
methods
products
steroid products
hormonal steroid
Prior art date
Application number
CR7022A
Other languages
English (en)
Inventor
Schultz Thomas
A Clark Bradley
Falzone Angela
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of CR7022A publication Critical patent/CR7022A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invencion se refiere a productos de hormona esteroide, tal como productos de anticonceptivos orales, incluyendo al menos un ingrediente activo de esteroide mezclado con un excipiente y que tiene una disolucion mejorada y propiedades de velocidad de liberacion.
CR7022A 2000-12-14 2003-07-14 Productos esteroides hormonales y metodos para su preparacion CR7022A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25566900P 2000-12-14 2000-12-14

Publications (1)

Publication Number Publication Date
CR7022A true CR7022A (es) 2009-02-23

Family

ID=22969374

Family Applications (1)

Application Number Title Priority Date Filing Date
CR7022A CR7022A (es) 2000-12-14 2003-07-14 Productos esteroides hormonales y metodos para su preparacion

Country Status (31)

Country Link
US (4) US7867990B2 (es)
EP (2) EP1591121B1 (es)
KR (1) KR100899032B1 (es)
CN (1) CN1290507C (es)
AT (2) ATE307591T1 (es)
AU (2) AU2742102A (es)
BG (1) BG66178B1 (es)
BR (1) BRPI0116793B8 (es)
CA (1) CA2431521E (es)
CR (1) CR7022A (es)
CY (1) CY1109404T1 (es)
CZ (1) CZ306435B6 (es)
DE (2) DE60114467T2 (es)
DK (2) DK1361881T3 (es)
EC (1) ECSP034654A (es)
EE (1) EE05358B1 (es)
ES (2) ES2327538T3 (es)
HK (2) HK1057174A1 (es)
HU (1) HU230400B1 (es)
IL (2) IL156423A0 (es)
ME (1) ME00339B (es)
MX (1) MXPA03005339A (es)
NO (2) NO334341B1 (es)
NZ (1) NZ526517A (es)
PT (1) PT1591121E (es)
RS (1) RS50414B (es)
RU (1) RU2286155C2 (es)
SK (1) SK288222B6 (es)
UA (1) UA77404C2 (es)
WO (1) WO2002047693A2 (es)
ZA (1) ZA200305342B (es)

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RU2016101363A (ru) * 2010-02-08 2018-11-21 Прэари Фармасьютикалз, Ллк Способ лечения заболеваний, связанных с глюкокортикоидной нечувствительностью
BR112014012444B1 (pt) 2011-11-23 2021-12-14 Therapeuticsmd, Inc Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher
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US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CN102793929B (zh) * 2012-09-07 2013-12-11 上海奥科达生物医药科技有限公司 一种制备稳定非晶态药物制剂的方法
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
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US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
JP2017516768A (ja) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然の併用ホルモン補充療法剤及び療法
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Also Published As

Publication number Publication date
EE05358B1 (et) 2010-12-15
KR100899032B1 (ko) 2009-05-21
HK1057174A1 (en) 2004-03-19
ATE307591T1 (de) 2005-11-15
WO2002047693A3 (en) 2002-11-07
NO20032708D0 (no) 2003-06-13
DE60139087D1 (de) 2009-08-06
HUP0400646A3 (en) 2012-08-28
US20020173669A1 (en) 2002-11-21
NO334341B1 (no) 2014-02-10
BRPI0116793B8 (pt) 2021-05-25
BR0116793A (pt) 2004-01-27
PT1591121E (pt) 2009-07-20
AU2742102A (en) 2002-06-24
ES2327538T3 (es) 2009-10-30
US20110046095A1 (en) 2011-02-24
AU2002227421B2 (en) 2007-08-23
DE60114467T2 (de) 2006-07-20
EP1591121A1 (en) 2005-11-02
MXPA03005339A (es) 2004-03-26
EP1361881A2 (en) 2003-11-19
CN1290507C (zh) 2006-12-20
DE60114467D1 (de) 2005-12-01
ECSP034654A (es) 2003-07-25
CN1489468A (zh) 2004-04-14
CA2431521C (en) 2010-03-16
ZA200305342B (en) 2004-10-11
ES2253451T3 (es) 2006-06-01
EE200300229A (et) 2003-08-15
UA77404C2 (en) 2006-12-15
ATE434439T1 (de) 2009-07-15
RS50414B (sr) 2009-12-31
HU230400B1 (hu) 2016-04-28
RU2003121240A (ru) 2005-02-10
EP1361881B1 (en) 2005-10-26
BRPI0116793B1 (pt) 2015-06-23
CA2431521E (en) 2013-04-16
NO20131334L (no) 2003-07-04
CZ20031896A3 (en) 2004-03-17
CZ306435B6 (cs) 2017-01-25
ME00339B (me) 2011-05-10
NZ526517A (en) 2005-09-30
HK1083457A1 (en) 2006-07-07
CA2431521A1 (en) 2002-06-20
HUP0400646A2 (hu) 2004-06-28
EP1591121B1 (en) 2009-06-24
YU47903A (sh) 2006-08-17
CY1109404T1 (el) 2014-07-02
WO2002047693A2 (en) 2002-06-20
KR20030061856A (ko) 2003-07-22
US20110046099A1 (en) 2011-02-24
MEP48808A (en) 2011-02-10
NO20032708L (no) 2003-07-04
SK288222B6 (sk) 2014-09-04
DK1361881T3 (da) 2006-02-20
IL156423A (en) 2010-04-29
SK8802003A3 (en) 2004-04-06
US20140309204A1 (en) 2014-10-16
DK1591121T3 (da) 2009-10-05
US7867990B2 (en) 2011-01-11
BG107958A (bg) 2004-11-30
BG66178B1 (bg) 2011-11-30
RU2286155C2 (ru) 2006-10-27
IL156423A0 (en) 2004-01-04

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