NO20021118L - Fremgangsmåte for fremstilling av citalopram - Google Patents

Fremgangsmåte for fremstilling av citalopram

Info

Publication number: NO20021118L
Authority: NO; Norway
Prior art keywords: citalopram; fluorophenyl; preparation; dimethylamine; rti
Prior art date: 2000-07-06

Application number

NO20021118A

Other languages

English (en)

Norwegian (no)

Other versions

NO20021118D0 (no

Inventor

Eva Bolzonella

Andrea Castellin

Andrea Nicole

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-06

Filing date

2002-03-06

Publication date

2002-04-24

2000-07-06 Priority claimed from PCT/EP2000/006426 external-priority patent/WO2001002383A2/en

2002-03-06 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2002-03-06 Publication of NO20021118D0 publication Critical patent/NO20021118D0/no

2002-04-24 Publication of NO20021118L publication Critical patent/NO20021118L/no

Links

WSEQXVZVJXJVFP-HXUWFJFHSA-N (R)-citalopram Chemical compound C1([C@@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-HXUWFJFHSA-N 0.000 title abstract 3
229960001653 citalopram Drugs 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
229910052749 magnesium Inorganic materials 0.000 abstract 2
239000011777 magnesium Substances 0.000 abstract 2
CGVBIXZVEMXIQU-UHFFFAOYSA-N 3-[1-(4-fluorophenyl)-3h-2-benzofuran-1-yl]-n,n-dimethylpropan-1-amine Chemical compound O1CC2=CC=CC=C2C1(CCCN(C)C)C1=CC=C(F)C=C1 CGVBIXZVEMXIQU-UHFFFAOYSA-N 0.000 abstract 1
-1 3-dimethylaminopropyl Chemical group 0.000 abstract 1
125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 abstract 1
239000007818 Grignard reagent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000004795 grignard reagents Chemical class 0.000 abstract 1
150000002680 magnesium Chemical class 0.000 abstract 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20021118A 2000-07-06 2002-03-06 Fremgangsmåte for fremstilling av citalopram NO20021118L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
PCT/EP2000/006426 WO2001002383A2 (en)	1999-07-06	2000-07-06	Process for the synthesis of citalopram
PCT/DK2001/000481 WO2002004435A1 (en)	2000-07-06	2001-07-06	Method for the preparation of citalopram

Publications (2)

Publication Number	Publication Date
NO20021118D0 NO20021118D0 (no)	2002-03-06
NO20021118L true NO20021118L (no)	2002-04-24

Family

ID=8164018

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20021118A NO20021118L (no)	2000-07-06	2002-03-06	Fremgangsmåte for fremstilling av citalopram

Country Status (11)

Country	Link
US (1)	US20020128497A1 (pt)
AU (1)	AU2001272368A1 (pt)
BR (1)	BR0106976A (pt)
CA (1)	CA2383963A1 (pt)
CZ (1)	CZ2002832A3 (pt)
EA (1)	EA200200332A1 (pt)
IL (1)	IL148525A0 (pt)
IS (1)	IS6293A (pt)
NO (1)	NO20021118L (pt)
SK (1)	SK3362002A3 (pt)
WO (1)	WO2002004435A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT1173431E (pt) *	1999-04-14	2003-09-30	Lundbeck & Co As H	Metodo de preparacao do citalopram
NL1017417C1 (nl)	2000-03-03	2001-03-16	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
CA2402553A1 (en)	2000-03-13	2001-09-20	H. Lundbeck A/S	Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
IES20010206A2 (en)	2000-03-13	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
TR200202166T2 (tr)	2000-03-13	2002-12-23	H. Lndbeck A/S	Sitalopramın preparasyon metodu
AU2001239213A1 (en)	2000-03-14	2001-09-24	H Lundbeck A/S	Method for the preparation of citalopram
MXPA02008652A (es) *	2000-03-16	2003-02-24	Lundbeck & Co As H	Metodo para la preparacion de 5-ciano-1-(4-fluorofenil)-1,3-dihidroisobenzofuranos.
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
US20050154052A1 (en) *	2003-03-24	2005-07-14	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
ITMI991579A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991581A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991486A1 (it) *	1999-07-06	2001-01-06	Vis Farmaceutici S P A	Processo per la sintesi di citalopram

2001
- 2001-07-06 BR BR0106976-4A patent/BR0106976A/pt not_active Application Discontinuation
- 2001-07-06 WO PCT/DK2001/000481 patent/WO2002004435A1/en not_active Application Discontinuation
- 2001-07-06 CZ CZ2002832A patent/CZ2002832A3/cs unknown
- 2001-07-06 AU AU2001272368A patent/AU2001272368A1/en not_active Abandoned
- 2001-07-06 SK SK336-2002A patent/SK3362002A3/sk unknown
- 2001-07-06 EA EA200200332A patent/EA200200332A1/ru unknown
- 2001-07-06 IL IL14852501A patent/IL148525A0/xx unknown
- 2001-07-06 CA CA002383963A patent/CA2383963A1/en not_active Abandoned
2002
- 2002-03-05 IS IS6293A patent/IS6293A/is unknown
- 2002-03-06 NO NO20021118A patent/NO20021118L/no not_active Application Discontinuation
- 2002-03-06 US US10/096,149 patent/US20020128497A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EA200200332A1 (ru)	2002-06-27
US20020128497A1 (en)	2002-09-12
BR0106976A (pt)	2002-07-23
CA2383963A1 (en)	2002-01-17
SK3362002A3 (en)	2002-08-06
WO2002004435A1 (en)	2002-01-17
AU2001272368A1 (en)	2002-01-21
IS6293A (is)	2002-03-05
CZ2002832A3 (cs)	2002-05-15
IL148525A0 (en)	2002-09-12
NO20021118D0 (no)	2002-03-06

Similar Documents

Publication	Publication Date	Title
NO20021118L (no)	2002-04-24	Fremgangsmåte for fremstilling av citalopram
YU68802A (sh)	2005-11-28	Kristalna baza citaloprama
ES2170734A1 (es)	2002-08-01	Metodo para la preparacion de citalopram.
CA1280421C (en)	1991-02-19	1,4-disubstituted piperidinyl derivatives
IES20010143A2 (en)	2001-07-25	Method for the preparation of citalopram
PE20080362A1 (es)	2008-04-25	Derivados de ciclohexilpirazol-lactama como inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1
NZ514982A (en)	2004-01-30	Method for the preparation of citalopram
Jiao et al.	2009	A Sequential O‐Nitrosoaldol and Grignard Addition Process: An Enantio‐and Diastereoselective Entry to Chiral 1, 2‐Diols
WO2001074741A3 (en)	2002-02-28	Catalytic asymmetric desymmetrization of meso compounds
BRPI0605934A2 (pt)	2009-05-26	processos para a preparação de ( 3r, 4s) - 4 - ( (4-benziloxi ) fenil ) - 1 - ( 4 - fluorofenil ) - 3 - ( (s) - 3 - ( 4 - fluorofenil ) - 3 - hidroxipropil) - 2 - azetidinona, um intermediário para a sìntese da ezetimiba
Palacios et al.	1996	Synthesis of secondary e-allylamines and β-aminophosphorylated compounds from β-functionalized enamines derived from phosphonium salts, phosphine oxides and phosphonates
DE60320766D1 (de)	2008-06-19	Synthese von indolthiazolverbindungen als liganden des ah-rezeptors
Yamazaki et al.	1988	Enantioselective total synthesis of (+)-monomorine I
BR0111472A (pt)	2004-01-06	Processo para a preparação de um composto, composto, e, forma polimórfica de um composto
WO2008059514A3 (en)	2009-04-02	Process for preparing escitalopram
WO2001002383A3 (en)	2001-05-03	Process for the synthesis of citalopram
Mueller et al.	2010	Catalytic Asymmetric 6π-Electrocyclization: Accessing Highly Substituted Optically Active 2-Pyrazolines via Diastereoselective Alkylations
BG107047A (en)	2003-04-30	Method for the preparation of citalopram
Roland et al.	2000	Addition of Grignard reagents to chiral 1, 2‐bisimines: a diasteroselective preparation of unsymmetrical 1, 2‐diamines
HUP0300180A2 (en)	2003-05-28	Method for the preparation of citalopram
Su et al.	2006	Copper catalyzed oxidation of organozinc halides
ATE361919T1 (de)	2007-06-15	Verfahren zur herstellung von gamma-butyrolacton
Felpin et al.	2003	A Novel Route to Chiral trans‐6‐Alkyl‐2‐hydroxymethyl‐1, 2, 5, 6‐tetrahydropyridines by Allylation of Chiral Imines and Ring‐Closing Metathesis− Total Synthesis of (−)‐3‐epi‐Deoxoprosopinine
Marqués‐López et al.	2008	Stereoselective, Temperature‐Dependent [2+ 2] Cycloaddition of N, N‐Dialkylhydrazones to N‐Benzyl‐N‐(benzyloxycarbonyl) aminoketene
Depature et al.	2001	3H‐Pyrroles, Alkylidene‐Pyrrolines and Functionalized Pyrrolidines by Radical Cyclization of β‐Allenyliminyl Radicals

Legal Events

Date	Code	Title	Description
2002-07-22	FC2A	Withdrawal, rejection or dismissal of laid open patent application