TR200202166T2 - Sitalopramın preparasyon metodu - Google Patents

Sitalopramın preparasyon metodu

Info

Publication number
TR200202166T2
TR200202166T2 TR2002/02166T TR200202166T TR200202166T2 TR 200202166 T2 TR200202166 T2 TR 200202166T2 TR 2002/02166 T TR2002/02166 T TR 2002/02166T TR 200202166 T TR200202166 T TR 200202166T TR 200202166 T2 TR200202166 T2 TR 200202166T2
Authority
TR
Turkey
Prior art keywords
citalopram
preparation
citalopramine
alkylating
fluorophenyl
Prior art date
Application number
TR2002/02166T
Other languages
English (en)
Inventor
Petersen Hans
Original Assignee
H. Lndbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lndbeck A/S filed Critical H. Lndbeck A/S
Publication of TR200202166T2 publication Critical patent/TR200202166T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)

Abstract

Bulus, bir 1-(4-florofenil)-1,3-dihidroizobenzofuran türevinin alkile edilmesi suretiyle sitalopramin hazirlanmasina yönelik metot ile ilgilidir.
TR2002/02166T 2000-03-13 2001-03-13 Sitalopramın preparasyon metodu TR200202166T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000401 2000-03-13
DKPA200000415 2000-03-14

Publications (1)

Publication Number Publication Date
TR200202166T2 true TR200202166T2 (tr) 2002-12-23

Family

ID=26068790

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/02166T TR200202166T2 (tr) 2000-03-13 2001-03-13 Sitalopramın preparasyon metodu

Country Status (22)

Country Link
US (2) US6762308B2 (tr)
EP (1) EP1265883A1 (tr)
JP (1) JP2003527387A (tr)
KR (1) KR20020080481A (tr)
CN (1) CN1429219A (tr)
AU (1) AU2001242298A1 (tr)
BG (1) BG107047A (tr)
BR (1) BR0109176A (tr)
CA (1) CA2402388A1 (tr)
CZ (1) CZ20023384A3 (tr)
EA (1) EA200200969A1 (tr)
HR (1) HRP20020744A2 (tr)
HU (1) HUP0300274A2 (tr)
IL (1) IL151490A0 (tr)
IS (1) IS6529A (tr)
MX (1) MXPA02008869A (tr)
NO (1) NO20024213L (tr)
NZ (1) NZ521201A (tr)
PL (1) PL360110A1 (tr)
SK (1) SK14602002A3 (tr)
TR (1) TR200202166T2 (tr)
WO (1) WO2001068631A1 (tr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1173431B2 (en) 1999-04-14 2009-08-26 H. Lundbeck A/S Method for the preparation of citalopram
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
TR200202195T2 (tr) * 2000-03-13 2002-12-23 H. Lundbeck A/S 5-Yer değiştirmiş 1-(4-florofenil)-1,3- dihidroizobenzofuran'ın adım adım alkillenmesi
CZ20023384A3 (cs) 2000-03-13 2003-01-15 H. Lundbeck A/S Způsob výroby citalopramu a meziprodukt
CA2402557A1 (en) 2000-03-14 2001-09-20 Hans Petersen Method for the preparation of citalopram
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
PE20040991A1 (es) 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
TWI339651B (en) 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
US7613106B2 (en) * 2005-01-04 2009-11-03 Avaya Inc. Dial plan transparency for fragmented networks
GB0601286D0 (en) 2006-01-23 2006-03-01 Sandoz Ag Asymmetric synthesis

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (tr) 1965-03-18
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
CN1206207C (zh) 1997-07-08 2005-06-15 H.隆德贝克有限公司 氰酞氟苯胺的制备方法
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
BR9714925A (pt) 1997-11-11 2003-07-22 Lundbeck & Co As H Método para preparação de citalopran, composto e composição farmacêutica antidepressiva
JP3892667B2 (ja) 1998-10-20 2007-03-14 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
WO2000039112A1 (en) 1998-12-23 2000-07-06 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
EP1173431B2 (en) 1999-04-14 2009-08-26 H. Lundbeck A/S Method for the preparation of citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
GB2360281B (en) 1999-10-25 2002-01-16 Lundbeck & Co As H Method for the preparation of citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
DE69915713T2 (de) 1999-12-28 2005-03-03 H. Lundbeck A/S Verfahren zur herstellung von citalopram
MXPA02006504A (es) 1999-12-30 2002-12-09 Lundbeck & Co As H Metodo para la preparacion de citalopram.
SI1254129T1 (en) 2000-01-14 2004-02-29 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
US6433196B1 (en) 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
FR2805812A1 (fr) 2000-02-24 2001-09-07 Lundbeck & Co As H Procede de preparation du citalopram
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
CZ20023384A3 (cs) 2000-03-13 2003-01-15 H. Lundbeck A/S Způsob výroby citalopramu a meziprodukt
CA2402557A1 (en) 2000-03-14 2001-09-20 Hans Petersen Method for the preparation of citalopram
MXPA02008652A (es) 2000-03-16 2003-02-24 Lundbeck & Co As H Metodo para la preparacion de 5-ciano-1-(4-fluorofenil)-1,3-dihidroisobenzofuranos.
EA200200332A1 (ru) 2000-07-06 2002-06-27 Х.Лундбекк А/С Способ получения циталопрама
IL144817A0 (en) 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
WO2001045483A2 (en) 2000-12-22 2001-06-28 H. Lundbeck A/S Method for the preparation of pure citalopram
EA003459B1 (ru) 2000-12-28 2003-06-26 Х.Лундбекк А/С Способ получения чистого циталопрама

Also Published As

Publication number Publication date
HUP0300274A2 (hu) 2003-06-28
NO20024213L (no) 2002-11-13
BR0109176A (pt) 2003-04-22
NO20024213D0 (no) 2002-09-04
IL151490A0 (en) 2003-04-10
US6992198B2 (en) 2006-01-31
IS6529A (is) 2002-08-27
US20040215025A1 (en) 2004-10-28
EP1265883A1 (en) 2002-12-18
HRP20020744A2 (en) 2004-12-31
CA2402388A1 (en) 2001-09-20
WO2001068631A1 (en) 2001-09-20
NZ521201A (en) 2004-02-27
JP2003527387A (ja) 2003-09-16
MXPA02008869A (es) 2003-02-10
PL360110A1 (en) 2004-09-06
EA200200969A1 (ru) 2003-02-27
CN1429219A (zh) 2003-07-09
US20030092919A1 (en) 2003-05-15
KR20020080481A (ko) 2002-10-23
BG107047A (en) 2003-04-30
SK14602002A3 (sk) 2003-02-04
CZ20023384A3 (cs) 2003-01-15
US6762308B2 (en) 2004-07-13
AU2001242298A1 (en) 2001-09-24

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