NO20012987D0 - IL-5-hemmende 6-azauraci derivater - Google Patents

IL-5-hemmende 6-azauraci derivater

Info

Publication number
NO20012987D0
NO20012987D0 NO20012987A NO20012987A NO20012987D0 NO 20012987 D0 NO20012987 D0 NO 20012987D0 NO 20012987 A NO20012987 A NO 20012987A NO 20012987 A NO20012987 A NO 20012987A NO 20012987 D0 NO20012987 D0 NO 20012987D0
Authority
NO
Norway
Prior art keywords
azauraci
inhibitory
derivatives
azauraci derivatives
Prior art date
Application number
NO20012987A
Other languages
English (en)
Other versions
NO20012987L (no
NO319814B1 (no
Inventor
Eddy Jean Edgard Freyne
Frederik Dirk Deroose
Werner Constant Joha Embrechts
Jean Fernand Armand Lacrampe
Jerome Michel Claude Fortin
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20012987D0 publication Critical patent/NO20012987D0/no
Publication of NO20012987L publication Critical patent/NO20012987L/no
Publication of NO319814B1 publication Critical patent/NO319814B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • C07D253/0651,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/071,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075Two hetero atoms, in positions 3 and 5
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
NO20012987A 1998-12-18 2001-06-15 IL-5-hemmende 6-azauraci derivater, fremgangsmater ved deres fremstilling og sammensetninger omfattende dem, samt deres anvendelse og fremgangsmate for merking av en reseptor og avbilding av et organ. NO319814B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98204336 1998-12-18
PCT/EP1999/010169 WO2000037451A1 (en) 1998-12-18 1999-12-16 Il-5 inhibiting 6-azauracil derivatives

Publications (3)

Publication Number Publication Date
NO20012987D0 true NO20012987D0 (no) 2001-06-15
NO20012987L NO20012987L (no) 2001-08-17
NO319814B1 NO319814B1 (no) 2005-09-19

Family

ID=8234494

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012987A NO319814B1 (no) 1998-12-18 2001-06-15 IL-5-hemmende 6-azauraci derivater, fremgangsmater ved deres fremstilling og sammensetninger omfattende dem, samt deres anvendelse og fremgangsmate for merking av en reseptor og avbilding av et organ.

Country Status (35)

Country Link
US (1) US6803364B1 (no)
EP (1) EP1140873B1 (no)
JP (1) JP2002533331A (no)
KR (1) KR100635721B1 (no)
CN (1) CN100343239C (no)
AR (1) AR021887A1 (no)
AT (1) ATE365723T1 (no)
AU (1) AU773780B2 (no)
BG (1) BG105602A (no)
BR (1) BR9916366A (no)
CA (1) CA2354511A1 (no)
CO (1) CO5150147A1 (no)
CZ (1) CZ20012062A3 (no)
DE (1) DE69936396T2 (no)
DK (1) DK1140873T3 (no)
EA (1) EA004806B1 (no)
EE (1) EE200100320A (no)
ES (1) ES2289835T3 (no)
HK (1) HK1042491A1 (no)
HR (1) HRP20010455A2 (no)
HU (1) HUP0104641A3 (no)
ID (1) ID28880A (no)
IL (1) IL143766A (no)
MY (1) MY125808A (no)
NO (1) NO319814B1 (no)
NZ (1) NZ512748A (no)
PL (1) PL198205B1 (no)
PT (1) PT1140873E (no)
SA (1) SA00201030B1 (no)
SK (1) SK8152001A3 (no)
TR (1) TR200101729T2 (no)
TW (1) TWI249530B (no)
UA (1) UA73107C2 (no)
WO (1) WO2000037451A1 (no)
ZA (1) ZA200104942B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8466096B2 (en) * 2007-04-26 2013-06-18 Afton Chemical Corporation 1,3,2-dioxaphosphorinane, 2-sulfide derivatives for use as anti-wear additives in lubricant compositions
RU2523651C2 (ru) * 2012-05-22 2014-07-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Владивостокский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО ВГМУ Минздравсоцразвития России) Способ дифференцированного контроля базисного противовоспалительного лечения бронхиальной астмы у детей и подростков
RU2506045C1 (ru) * 2012-09-05 2014-02-10 Федеральное государственное бюджетное учреждение "Дальневосточный научный центр физиологии и патологии дыхания" Сибирского отделения РАМН Способ прогнозирования достижения контроля бронхиальной астмы

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2149645A1 (de) 1970-10-07 1972-09-14 Pfizer 2-Phenyl-as-triazin-3.5-(2H,4H)-dione und die Verwendung dieser Verbindungen zur Bekaempfung der Coccidiose
US3912723A (en) 1971-03-29 1975-10-14 Pfizer 2-Phenyl-as-triazine-3,5(2H,4H)diones
US3883528A (en) 1974-04-19 1975-05-13 Pfizer Preparation of 2(aryl)-as-triazine-3,5(2H,4H)-dione coccidiostats
CA1244024A (en) 1984-08-01 1988-11-01 Gustaaf M. Boeckx .alpha.- ARYL-4-(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN- 2(3H)-YL)BENZENEACETONITRILES
US4631278A (en) 1984-08-01 1986-12-23 Janssen Pharmaceutica N.V. Anti-protozoal α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitrile derivatives, pharmaceutical compositions, and method of use therefor
GB8602342D0 (en) * 1986-01-30 1986-03-05 Janssen Pharmaceutica Nv 5 6-dihydro-2-(substituted phenyl)-1 2 4-triazine-3 5(2h 4h)-diones
CA1331757C (en) 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
EP0476439A1 (de) 1990-09-18 1992-03-25 Bayer Ag Substituierte 1,2,4-Triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung
DE4120138A1 (de) 1991-06-19 1992-12-24 Bayer Ag Substituierte hexahydro-1,2,4-triazindione, verfahren zu ihrer herstellung, zwischenprodukte dafuer und ihre verwendung
TW263495B (no) 1992-12-23 1995-11-21 Celltech Ltd
GB9304920D0 (en) 1993-03-10 1993-04-28 Celltech Ltd Chemical compounds
TW403741B (en) 1993-10-15 2000-09-01 Takeda Chemical Industries Ltd Triazine derivative, production and use thereof
TW332201B (en) 1995-04-06 1998-05-21 Janssen Pharmaceutica Nv 1,3-Dihydro-1-(phenylalkyl)-2H-imidazol-2-one derivatives
DE69615601T2 (de) 1995-04-14 2002-07-11 Takeda Schering Plough Animal Verfahren zur Herstellung von Triazinderivate
EP0831088B1 (en) 1996-08-30 2002-11-27 Takeda Schering-Plough Animal Health K.K. 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents
KR20010014049A (ko) * 1997-07-10 2001-02-26 디르크 반테 Il-5를 저해하는 6-아자우라실 유도체
PL337875A1 (en) 1997-07-10 2000-09-11 Janssen Pharmaceutica Nv Derivatives of 6-azauracil as il-5 inhibitors

Also Published As

Publication number Publication date
HRP20010455A2 (en) 2002-06-30
DE69936396D1 (de) 2007-08-09
DK1140873T3 (da) 2007-10-15
EA004806B1 (ru) 2004-08-26
MY125808A (en) 2006-08-30
KR20010080617A (ko) 2001-08-22
HUP0104641A3 (en) 2003-01-28
CN1330643A (zh) 2002-01-09
NZ512748A (en) 2004-05-28
DE69936396T2 (de) 2008-06-19
EE200100320A (et) 2002-10-15
PL198205B1 (pl) 2008-06-30
ES2289835T3 (es) 2008-02-01
TR200101729T2 (tr) 2001-10-22
AU2100100A (en) 2000-07-12
HK1042491A1 (zh) 2002-08-16
US6803364B1 (en) 2004-10-12
CA2354511A1 (en) 2000-06-29
ID28880A (id) 2001-07-12
ATE365723T1 (de) 2007-07-15
SK8152001A3 (en) 2002-04-04
ZA200104942B (en) 2002-06-18
PT1140873E (pt) 2007-10-10
NO20012987L (no) 2001-08-17
EA200100677A1 (ru) 2001-12-24
CN100343239C (zh) 2007-10-17
CO5150147A1 (es) 2002-04-29
SA00201030B1 (ar) 2006-10-11
IL143766A0 (en) 2002-04-21
IL143766A (en) 2005-11-20
AR021887A1 (es) 2002-08-07
BG105602A (en) 2002-01-31
HUP0104641A2 (hu) 2002-04-29
KR100635721B1 (ko) 2006-10-17
CZ20012062A3 (cs) 2002-03-13
EP1140873B1 (en) 2007-06-27
NO319814B1 (no) 2005-09-19
AU773780B2 (en) 2004-06-03
TWI249530B (en) 2006-02-21
JP2002533331A (ja) 2002-10-08
BR9916366A (pt) 2001-09-18
UA73107C2 (en) 2005-06-15
EP1140873A1 (en) 2001-10-10
WO2000037451A1 (en) 2000-06-29

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