ATE364597T1 - Il-5 hemmende 6-azauracilderivate - Google Patents
Il-5 hemmende 6-azauracilderivateInfo
- Publication number
- ATE364597T1 ATE364597T1 AT98941299T AT98941299T ATE364597T1 AT E364597 T1 ATE364597 T1 AT E364597T1 AT 98941299 T AT98941299 T AT 98941299T AT 98941299 T AT98941299 T AT 98941299T AT E364597 T1 ATE364597 T1 AT E364597T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibiting
- azauracil derivatives
- azauracil
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97202118 | 1997-07-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE364597T1 true ATE364597T1 (de) | 2007-07-15 |
Family
ID=8228531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98941299T ATE364597T1 (de) | 1997-07-10 | 1998-07-07 | Il-5 hemmende 6-azauracilderivate |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP1000040B1 (de) |
JP (1) | JP2002511882A (de) |
KR (1) | KR20010014049A (de) |
CN (1) | CN1262679A (de) |
AR (1) | AR013360A1 (de) |
AT (1) | ATE364597T1 (de) |
AU (1) | AU742145B2 (de) |
BR (1) | BR9811678A (de) |
CA (1) | CA2294145A1 (de) |
DE (1) | DE69837922D1 (de) |
EE (1) | EE200000016A (de) |
HR (1) | HRP20000003A2 (de) |
HU (1) | HUP0004687A3 (de) |
ID (1) | ID24390A (de) |
IL (1) | IL133916A0 (de) |
NO (1) | NO20000063L (de) |
NZ (1) | NZ502180A (de) |
PL (1) | PL337947A1 (de) |
SK (1) | SK183999A3 (de) |
TR (1) | TR200000153T2 (de) |
TW (1) | TW496865B (de) |
WO (1) | WO1999002505A1 (de) |
ZA (1) | ZA986089B (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1100483B1 (de) * | 1998-07-30 | 2004-09-29 | Abbott Laboratories | Glucocorticoid selektive entzündungshemmende mittel |
EP0987265A1 (de) * | 1998-09-18 | 2000-03-22 | Janssen Pharmaceutica N.V. | Interleukin-5 hemmende 6-Azauracil Derivate |
EE200100320A (et) * | 1998-12-18 | 2002-10-15 | Janssen Pharmaceutica N.V. | 6-asauratsiili derivaadid, nende valmistamismeetod ja kasutamine, kompositsioon ja selle valmistamismeetod, retseptori märgistamismeetod ja organi visualiseerimismeetod |
CZ2002356A3 (cs) | 1999-08-06 | 2002-06-12 | Janssen Pharmaceutica N. V. | Deriváty 6-azauracilu inhibující interleukin-5 |
WO2002004411A1 (en) | 2000-07-07 | 2002-01-17 | The Administrators Of The Tulane Educational Fund | Methods for protection of stratified squamous epithelium against injury by noxious substances and novel agents for use therefor |
US7183276B2 (en) | 2002-02-28 | 2007-02-27 | Takeda Pharmaceutical Company Limited | Azole compounds |
WO2004071448A2 (en) * | 2003-02-12 | 2004-08-26 | Transtech Pharma Inc. | Substituted azole derivatives as inhibitors of protein tyrosine phosphatases |
GB0305575D0 (en) | 2003-03-11 | 2003-04-16 | Glaxo Group Ltd | Novel compounds |
WO2005116001A1 (en) * | 2004-05-29 | 2005-12-08 | 7Tm Pharma A/S | Substituted thiazoleacetic as crth2 ligands |
DE102006049618A1 (de) * | 2006-10-20 | 2008-05-08 | Tschesche, Harald, Prof. Dr. | Triazine und Ihre Verwendung als Metalloproteinase-Inhibitoren |
CN101265238B (zh) * | 2007-12-12 | 2010-06-16 | 重庆天极旅业有限公司 | 一种三嗪环衍生物的合成方法 |
CN101265216B (zh) * | 2007-12-18 | 2012-06-27 | 重庆华邦胜凯制药有限公司 | 4-(取代乙氰基)-苯腙衍生物及其合成方法 |
NZ605690A (en) * | 2010-08-16 | 2014-06-27 | Boehringer Ingelheim Int | Oxadiazole inhibitors of leukotriene production |
AU2017297812A1 (en) * | 2016-07-13 | 2019-02-07 | Assistance Publique - Hopitaux De Paris | Meclozine derivatives and diclazuril derivatives for use in the prevention and/or the treatment of disorders associated to the inflammation induced by P. acnes |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2149645A1 (de) * | 1970-10-07 | 1972-09-14 | Pfizer | 2-Phenyl-as-triazin-3.5-(2H,4H)-dione und die Verwendung dieser Verbindungen zur Bekaempfung der Coccidiose |
US3912723A (en) * | 1971-03-29 | 1975-10-14 | Pfizer | 2-Phenyl-as-triazine-3,5(2H,4H)diones |
US3883528A (en) * | 1974-04-19 | 1975-05-13 | Pfizer | Preparation of 2(aryl)-as-triazine-3,5(2H,4H)-dione coccidiostats |
CA1244024A (en) * | 1984-08-01 | 1988-11-01 | Gustaaf M. Boeckx | .alpha.- ARYL-4-(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN- 2(3H)-YL)BENZENEACETONITRILES |
GB8602342D0 (en) * | 1986-01-30 | 1986-03-05 | Janssen Pharmaceutica Nv | 5 6-dihydro-2-(substituted phenyl)-1 2 4-triazine-3 5(2h 4h)-diones |
EP0476439A1 (de) * | 1990-09-18 | 1992-03-25 | Bayer Ag | Substituierte 1,2,4-Triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung |
RU2146674C1 (ru) * | 1993-10-15 | 2000-03-20 | Такеда Кемикал Индастриз, Лтд. | Производные триазина, способы их получения, антипротозойная композиция, добавка в пищу животных, способ ингибирования протозои у животных |
-
1998
- 1998-07-07 HU HU0004687A patent/HUP0004687A3/hu unknown
- 1998-07-07 AT AT98941299T patent/ATE364597T1/de not_active IP Right Cessation
- 1998-07-07 JP JP50812699A patent/JP2002511882A/ja not_active Withdrawn
- 1998-07-07 TR TR2000/00153T patent/TR200000153T2/xx unknown
- 1998-07-07 SK SK1839-99A patent/SK183999A3/sk unknown
- 1998-07-07 NZ NZ502180A patent/NZ502180A/xx unknown
- 1998-07-07 DE DE69837922T patent/DE69837922D1/de not_active Expired - Lifetime
- 1998-07-07 CN CN98806978A patent/CN1262679A/zh active Pending
- 1998-07-07 ID IDW20000034A patent/ID24390A/id unknown
- 1998-07-07 KR KR19997012079A patent/KR20010014049A/ko not_active Application Discontinuation
- 1998-07-07 CA CA002294145A patent/CA2294145A1/en not_active Abandoned
- 1998-07-07 EE EEP200000016A patent/EE200000016A/xx unknown
- 1998-07-07 BR BR9811678-9A patent/BR9811678A/pt not_active IP Right Cessation
- 1998-07-07 EP EP98941299A patent/EP1000040B1/de not_active Expired - Lifetime
- 1998-07-07 WO PCT/EP1998/004191 patent/WO1999002505A1/en active IP Right Grant
- 1998-07-07 IL IL13391698A patent/IL133916A0/xx unknown
- 1998-07-07 AU AU89738/98A patent/AU742145B2/en not_active Ceased
- 1998-07-07 PL PL98337947A patent/PL337947A1/xx unknown
- 1998-07-08 TW TW087111014A patent/TW496865B/zh active
- 1998-07-08 AR ARP980103336A patent/AR013360A1/es not_active Application Discontinuation
- 1998-07-09 ZA ZA9806089A patent/ZA986089B/xx unknown
-
2000
- 2000-01-05 HR HR20000003A patent/HRP20000003A2/xx not_active Application Discontinuation
- 2000-01-06 NO NO20000063A patent/NO20000063L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN1262679A (zh) | 2000-08-09 |
BR9811678A (pt) | 2000-09-19 |
EP1000040A1 (de) | 2000-05-17 |
EP1000040B1 (de) | 2007-06-13 |
KR20010014049A (ko) | 2001-02-26 |
HRP20000003A2 (en) | 2000-12-31 |
AU8973898A (en) | 1999-02-08 |
JP2002511882A (ja) | 2002-04-16 |
EE200000016A (et) | 2000-10-16 |
ID24390A (id) | 2000-07-13 |
NZ502180A (en) | 2000-11-24 |
TW496865B (en) | 2002-08-01 |
IL133916A0 (en) | 2001-04-30 |
ZA986089B (en) | 2000-01-10 |
HUP0004687A2 (hu) | 2002-02-28 |
DE69837922D1 (de) | 2007-07-26 |
AU742145B2 (en) | 2001-12-20 |
TR200000153T2 (tr) | 2000-07-21 |
CA2294145A1 (en) | 1999-01-21 |
AR013360A1 (es) | 2000-12-27 |
NO20000063L (no) | 2000-03-10 |
HUP0004687A3 (en) | 2002-03-28 |
SK183999A3 (en) | 2000-08-14 |
NO20000063D0 (no) | 2000-01-06 |
PL337947A1 (en) | 2000-09-11 |
WO1999002505A1 (en) | 1999-01-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |