NO179710C - Nye fosfolipidderivater av nukleosider, og legemiddel inneholdende disse - Google Patents

Nye fosfolipidderivater av nukleosider, og legemiddel inneholdende disse

Info

Publication number
NO179710C
NO179710C NO930587A NO930587A NO179710C NO 179710 C NO179710 C NO 179710C NO 930587 A NO930587 A NO 930587A NO 930587 A NO930587 A NO 930587A NO 179710 C NO179710 C NO 179710C
Authority
NO
Norway
Prior art keywords
nucleosides
drug containing
phospholipid derivatives
novel phospholipid
novel
Prior art date
Application number
NO930587A
Other languages
English (en)
Other versions
NO930587D0 (no
NO930587L (no
NO179710B (no
Inventor
Harald Zilch
Herbert Leinert
Alfred Mertens
Dieter Herrmann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25896049&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO179710(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of NO930587D0 publication Critical patent/NO930587D0/no
Publication of NO930587L publication Critical patent/NO930587L/no
Publication of NO179710B publication Critical patent/NO179710B/no
Publication of NO179710C publication Critical patent/NO179710C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO930587A 1990-08-20 1993-02-19 Nye fosfolipidderivater av nukleosider, og legemiddel inneholdende disse NO179710C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4026265A DE4026265A1 (de) 1990-08-20 1990-08-20 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
PCT/EP1991/001541 WO1992003462A1 (de) 1990-08-20 1991-08-14 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
US08/661,038 US5756711A (en) 1990-08-20 1996-06-10 Phospholipid derivatives of nucleosides and their use as anti-viral medicaments

Publications (4)

Publication Number Publication Date
NO930587D0 NO930587D0 (no) 1993-02-19
NO930587L NO930587L (no) 1993-02-19
NO179710B NO179710B (no) 1996-08-26
NO179710C true NO179710C (no) 1996-12-04

Family

ID=25896049

Family Applications (1)

Application Number Title Priority Date Filing Date
NO930587A NO179710C (no) 1990-08-20 1993-02-19 Nye fosfolipidderivater av nukleosider, og legemiddel inneholdende disse

Country Status (15)

Country Link
US (1) US5756711A (no)
EP (1) EP0545966B1 (no)
CN (1) CN1032258C (no)
AT (1) ATE114316T1 (no)
CA (1) CA2090024C (no)
DE (2) DE4026265A1 (no)
DK (1) DK0545966T3 (no)
ES (1) ES2066461T3 (no)
FI (1) FI104176B (no)
HK (1) HK35597A (no)
IE (1) IE64374B1 (no)
NO (1) NO179710C (no)
PT (1) PT98720B (no)
SK (1) SK281826B6 (no)
WO (1) WO1992003462A1 (no)

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DE4204031A1 (de) * 1992-02-12 1993-08-19 Boehringer Mannheim Gmbh Neue lipidphosphonsaeure-nucleosid-konjugate sowie deren verwendung als antivirale arzneimittel
DE4204032A1 (de) * 1992-02-12 1993-08-19 Boehringer Mannheim Gmbh Neue liponucleotide, deren herstellunmg sowie deren verwendung als antivirale arzneimittel
US6080734A (en) * 1992-08-08 2000-06-27 Roche Diagnostic Gmbh Liponucleotides of seco-nucleosides, their production as well as their use as antiviral pharmaceutical agents
DE4226279A1 (de) * 1992-08-08 1994-02-10 Boehringer Mannheim Gmbh Liponucleotide von Seco-Nucleosiden, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
ATE226437T1 (de) * 1993-06-10 2002-11-15 Univ Wake Forest (phospho)lipide zum bekämpfen einer hepatitis b- infektion
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DE4418690A1 (de) * 1994-05-28 1996-01-11 Boehringer Mannheim Gmbh Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel
CA2197319C (en) * 1994-08-29 2009-01-27 Louis S. Kucera Lipid analogs for treating viral infections
US7135584B2 (en) 1995-08-07 2006-11-14 Wake Forest University Lipid analogs for treating viral infections
EP0791056B1 (de) * 1994-11-12 2005-03-30 Heidelberg Pharma GmbH Lipidspaltender enzymkomplex
DE19505168A1 (de) * 1995-02-16 1996-08-22 Boehringer Mannheim Gmbh Spezifische Lipidkonjugate von Nucleosid-Diphosphonaten und deren Verwendung als Arzneimittel
DE19547022A1 (de) * 1995-12-15 1997-06-19 Boehringer Mannheim Gmbh Kovalente Lipid-Phosphonocarbonsäure-Konjugate, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
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DE19602757A1 (de) * 1996-01-26 1997-07-31 Boehringer Mannheim Gmbh Feste Instant-Release-Darreichungsformen und Verfahren zu ihrer Herstellung
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DE10156910A1 (de) * 2001-11-21 2003-06-05 Heidelberg Pharma Holding Gmbh Phospholipid-Derivate von Nucleosiden als antitumorale Arzneimittel
EP1448579A1 (de) * 2001-11-21 2004-08-25 Heidelberg Pharma Holding GmbH Phospholipid-derivate von nucleosiden als antitumorale arzneimittel
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WO2006068760A2 (en) * 2004-11-19 2006-06-29 The Regents Of The University Of California Anti-inflammatory pyrazolopyrimidines
ES2401285T3 (es) 2004-12-16 2013-04-18 The Regents Of The University Of California Fármacos con el pulmón como diana
BRPI0519306A2 (pt) 2004-12-30 2009-01-06 Medivir Ab compostos éteis no tratamento de hiv
EP2842559A3 (en) 2005-04-08 2015-03-18 Chimerix, Inc. Compounds, compositions and methods for the treatment of viral infections and other medical disorders
EP1868628B1 (en) 2005-04-08 2014-06-11 Chimerix, Inc. Compounds, compositions and methods for the treatment of poxvirus infections
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US8993580B2 (en) 2008-03-14 2015-03-31 Intellikine Llc Benzothiazole kinase inhibitors and methods of use
US20110224223A1 (en) * 2008-07-08 2011-09-15 The Regents Of The University Of California, A California Corporation MTOR Modulators and Uses Thereof
BRPI0915231A2 (pt) 2008-07-08 2018-06-12 Intellikine Inc compostos inibidores de quinase e métodos de uso
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US8697709B2 (en) 2008-10-16 2014-04-15 The Regents Of The University Of California Fused ring heteroaryl kinase inhibitors
US8476282B2 (en) * 2008-11-03 2013-07-02 Intellikine Llc Benzoxazole kinase inhibitors and methods of use
EP2427195B1 (en) 2009-05-07 2019-05-01 Intellikine, LLC Heterocyclic compounds and uses thereof
WO2011011519A1 (en) 2009-07-21 2011-01-27 Chimerix, Inc. Compounds, compositions and methods for treating ocular conditions
US8980899B2 (en) 2009-10-16 2015-03-17 The Regents Of The University Of California Methods of inhibiting Ire1
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EP2563367A4 (en) 2010-04-26 2013-12-04 Chimerix Inc METHODS OF TREATING RETROVIRAL INFECTIONS AND ASSOCIATED DOSAGE REGIMES
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Also Published As

Publication number Publication date
IE64374B1 (en) 1995-07-26
FI930753A (fi) 1993-02-19
DE59103595D1 (de) 1995-01-05
NO930587D0 (no) 1993-02-19
DK0545966T3 (da) 1995-05-08
CA2090024A1 (en) 1992-02-21
PT98720A (pt) 1992-07-31
FI104176B1 (fi) 1999-11-30
AU654670B2 (en) 1994-11-17
HK35597A (en) 1997-03-27
EP0545966A1 (de) 1993-06-16
PT98720B (pt) 1999-02-26
EP0545966B1 (de) 1994-11-23
US5756711A (en) 1998-05-26
AU8325191A (en) 1992-03-17
ATE114316T1 (de) 1994-12-15
CN1032258C (zh) 1996-07-10
NO930587L (no) 1993-02-19
NO179710B (no) 1996-08-26
FI104176B (fi) 1999-11-30
CA2090024C (en) 2000-05-02
FI930753A0 (fi) 1993-02-19
DE4026265A1 (de) 1992-02-27
SK281826B6 (sk) 2001-08-06
SK9293A3 (en) 1993-07-07
WO1992003462A1 (de) 1992-03-05
ES2066461T3 (es) 1995-03-01
CN1059149A (zh) 1992-03-04
IE912930A1 (en) 1992-02-26

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