NO137012C - Analogifremgangsm}te for fremstilling av terapeutisk aktive pyrazolo (1,5-a)-pyrimidiner - Google Patents
Analogifremgangsm}te for fremstilling av terapeutisk aktive pyrazolo (1,5-a)-pyrimidinerInfo
- Publication number
- NO137012C NO137012C NO4476/72A NO447672A NO137012C NO 137012 C NO137012 C NO 137012C NO 4476/72 A NO4476/72 A NO 4476/72A NO 447672 A NO447672 A NO 447672A NO 137012 C NO137012 C NO 137012C
- Authority
- NO
- Norway
- Prior art keywords
- pyrimidines
- preparation
- therapeutic active
- analogical procedure
- active pyrazolo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20653871A | 1971-12-09 | 1971-12-09 | |
| US245870A US3925385A (en) | 1972-04-20 | 1972-04-20 | 6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines |
| US27346572A | 1972-07-20 | 1972-07-20 | |
| US29984072A | 1972-10-24 | 1972-10-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO137012B NO137012B (no) | 1977-09-05 |
| NO137012C true NO137012C (no) | 1977-12-14 |
Family
ID=27498614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO4476/72A NO137012C (no) | 1971-12-09 | 1972-12-06 | Analogifremgangsm}te for fremstilling av terapeutisk aktive pyrazolo (1,5-a)-pyrimidiner |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS4864097A (de) |
| BE (1) | BE792533A (de) |
| BG (1) | BG22401A3 (de) |
| CH (1) | CH603652A5 (de) |
| DD (1) | DD104530A5 (de) |
| DE (1) | DE2257547A1 (de) |
| GB (1) | GB1412017A (de) |
| HU (1) | HU168530B (de) |
| IE (1) | IE37189B1 (de) |
| IL (1) | IL40895A (de) |
| LU (1) | LU66597A1 (de) |
| NL (1) | NL7216539A (de) |
| NO (1) | NO137012C (de) |
| RO (1) | RO62762A (de) |
| SE (1) | SE398751B (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281000A (en) * | 1979-07-09 | 1981-07-28 | American Cyanamid Company | Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents |
| AU557300B2 (en) * | 1982-03-16 | 1986-12-18 | Farmitalia Carlo Erba S.P.A. | Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation |
| ZA831407B (en) * | 1982-03-25 | 1983-11-30 | Erba Farmitalia | Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation |
| NZ208554A (en) * | 1983-06-23 | 1987-06-30 | American Cyanamid Co | (aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions |
| DE3533050A1 (de) * | 1985-09-17 | 1987-03-26 | Basf Ag | 7-amino-azolo(1,5-a)pyrimidine, verfahren zu ihrer herstellung und diese enthaltende fungizide, bzw. deren verwendung als fungizide |
| CA1330079C (en) * | 1988-10-13 | 1994-06-07 | Michihiko Tsujitani | Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same |
| KR100191774B1 (ko) * | 1991-04-22 | 1999-06-15 | 오스카 아끼히꼬 | 피라졸로[1,5-알파] 피리미딘 유도체 및 이것을 함유하는 항염증제 |
| DE4333705C2 (de) * | 1993-10-02 | 2003-10-30 | Guenter Ege | Arylmethylsubstituierte Pyrazolo-azine, insbesondere 3-Arylmethylpyrazolo[1,5-a]pyrimidine und Verfahren zur Herstellung von 8-Arylmethyl-pyrazolo[5,1-c][1,2,4]triazinen |
| KR100315837B1 (ko) * | 1994-06-21 | 2002-02-28 | 고리 히데아끼 | 피라졸로[1,5-a]피리미딘유도체 |
| US5843951A (en) * | 1995-09-28 | 1998-12-01 | Otsuka Pharmaceutical Factory Inc. | Analgesic composition of pyrazolo(1,5-A) pyrimidines |
| FR2771631B1 (fr) | 1997-12-03 | 2001-02-02 | Oreal | Compositions de teinture des fibres keratiniques contenant des 3-amino pyrazolo-[1,5-a]-pyrimidines, procede de teinture, nouvelles 3-amino pyrazolo- [1,5-a]-pyrimidines et leur procede de preparation |
| AU2003263071B2 (en) * | 2002-09-04 | 2007-03-15 | Merck Sharp & Dohme Llc | Pyrazolopyrimidines as cyclin-dependent kinase inhibitors |
| US7119200B2 (en) * | 2002-09-04 | 2006-10-10 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| US7161003B1 (en) | 2002-09-04 | 2007-01-09 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| ES2222813B1 (es) * | 2003-07-24 | 2005-12-16 | Ferrer Internacional, S.A. | N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados. |
| TWI252851B (en) * | 2003-07-24 | 2006-04-11 | Ferrer Int | 7-substituted 3-nitro-pyrazolo[1,5-a]pyrimidines and compositions and methods related thereto |
| EP2989106B1 (de) | 2013-04-25 | 2016-12-14 | Beigene, Ltd. | Kondensierte heterocyclische verbindungen als proteinkinasehemmer |
| ES2792183T3 (es) | 2013-09-13 | 2020-11-10 | Beigene Switzerland Gmbh | Anticuerpos anti-PD1 y su uso como productos terapéuticos y de diagnóstico |
| CN110156892B (zh) | 2014-07-03 | 2023-05-16 | 百济神州有限公司 | 抗pd-l1抗体及其作为治疗剂及诊断剂的用途 |
| CN109475536B (zh) | 2016-07-05 | 2022-05-27 | 百济神州有限公司 | 用于治疗癌症的PD-l拮抗剂和RAF抑制剂的组合 |
| CN109563099B (zh) | 2016-08-16 | 2023-02-03 | 百济神州有限公司 | 一种化合物的晶型、其制备和用途 |
| WO2018033135A1 (en) | 2016-08-19 | 2018-02-22 | Beigene, Ltd. | Use of a combination comprising a btk inhibitor for treating cancers |
| TWI774726B (zh) | 2017-01-25 | 2022-08-21 | 英屬開曼群島商百濟神州有限公司 | (S)-7-(1-(丁-2-炔醯基)哌啶-4-基)-2-(4-苯氧基苯基)-4,5,6,7-四氫吡唑并[1,5-a]嘧啶-3-甲醯胺的晶型、及其製備和用途 |
| CN110799543A (zh) | 2017-06-26 | 2020-02-14 | 百济神州有限公司 | 肝细胞癌的免疫治疗 |
| US11377449B2 (en) | 2017-08-12 | 2022-07-05 | Beigene, Ltd. | BTK inhibitors with improved dual selectivity |
| CN111801334B (zh) | 2017-11-29 | 2023-06-09 | 百济神州瑞士有限责任公司 | 使用包含btk抑制剂的组合治疗惰性或侵袭性b-细胞淋巴瘤 |
| US11786531B1 (en) | 2022-06-08 | 2023-10-17 | Beigene Switzerland Gmbh | Methods of treating B-cell proliferative disorder |
-
0
- BE BE792533D patent/BE792533A/xx unknown
-
1972
- 1972-11-21 IE IE1612/72A patent/IE37189B1/xx unknown
- 1972-11-22 IL IL40895A patent/IL40895A/en unknown
- 1972-11-23 DE DE2257547A patent/DE2257547A1/de active Pending
- 1972-12-01 GB GB5558772A patent/GB1412017A/en not_active Expired
- 1972-12-05 SE SE7215829A patent/SE398751B/xx unknown
- 1972-12-05 LU LU66597A patent/LU66597A1/xx unknown
- 1972-12-06 NL NL7216539A patent/NL7216539A/xx not_active Application Discontinuation
- 1972-12-06 NO NO4476/72A patent/NO137012C/no unknown
- 1972-12-06 CH CH1775172A patent/CH603652A5/xx not_active IP Right Cessation
- 1972-12-07 DD DD167370A patent/DD104530A5/xx unknown
- 1972-12-08 HU HUIE548A patent/HU168530B/hu unknown
- 1972-12-09 BG BG22071A patent/BG22401A3/xx unknown
- 1972-12-09 JP JP47123877A patent/JPS4864097A/ja active Pending
- 1972-12-09 RO RO7200073093A patent/RO62762A/ro unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LU66597A1 (de) | 1973-03-15 |
| IL40895A (en) | 1976-12-31 |
| BG22401A3 (de) | 1977-02-20 |
| IL40895A0 (en) | 1973-01-30 |
| CH603652A5 (de) | 1978-08-31 |
| JPS4864097A (de) | 1973-09-05 |
| IE37189L (en) | 1973-06-09 |
| RO62762A (fr) | 1978-05-15 |
| HU168530B (de) | 1976-05-28 |
| SE398751B (sv) | 1978-01-16 |
| GB1412017A (en) | 1975-10-29 |
| BE792533A (fr) | 1973-06-08 |
| NL7216539A (de) | 1973-06-13 |
| DE2257547A1 (de) | 1973-06-14 |
| NO137012B (no) | 1977-09-05 |
| DD104530A5 (de) | 1974-03-12 |
| IE37189B1 (en) | 1977-05-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO137012C (no) | Analogifremgangsm}te for fremstilling av terapeutisk aktive pyrazolo (1,5-a)-pyrimidiner | |
| NO140301C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazo(5,1-f)-as-triaziner | |
| SE402915B (sv) | Forfarande for framstellning av imidazo(5,1-f)triazinoner med terapeutisk verkan | |
| NO136843C (no) | Analogifremgangsm}te til fremstilling av terapeutisk aktive derivater av 5,6-dihydro-pyrrolo (3,4-b) pyrazin | |
| SE402592B (sv) | Forfarande for framstellning av 2-alkyl-3-acyl-pyrazolo(1,5-a)pyridiner | |
| NO143219C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive forbindelser. | |
| NO136837C (no) | Analogifremgangsm}te for fremstilling av terapeutisk aktive pleuromutiliner | |
| NO136793C (no) | Analogifremgangsm}te til fremstilling av terapeutisk virksomme substituerte 1,2,4-triazolderivater. | |
| NO136045C (no) | Analogifremgangsm}te for fremstilling av terapeutisk aktive pyridazinoner. | |
| AR193536A1 (es) | Procedimiento para la preparacion de compuestos de pirazolo(1,5a)pirimidina | |
| NO138566C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 2,1,3-benzotiadiazol-derivater | |
| NO139685C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive isoindolin-derivater | |
| SE396388B (sv) | Analogiforfrande for framstellning av 2,3-dihydro-oxo-imidazo-/1,2-a/pyrimidiner | |
| NO136251C (no) | Analogifremgangsm}te for fremstilling av terapeutisk aktive pyridazin-derivater. | |
| SE389499B (sv) | Analogiforfarande for framstellning av triazolo(4,3-a)(1,4)bensodiazepin-derivat | |
| FI54121B (fi) | Foerfarande foer framstaellning av blodtryckssaenkande imidazo-(1,2-a)-imidazoler -pyrimidiner och diazepiner och deras syraadditionssalter | |
| SE402012B (sv) | Analogiforfarande for framstellning av s-triazolo(1,5-a)(1,4)diazepinderivat | |
| SE410604B (sv) | Analogiforfarande for framstellning av pyrazolo(3,4-e)(1,4)diazepinforeningar | |
| SE400551B (sv) | Forfarande for framstellning av terapeutiskt aktiva 3-amino-5-karbamylbensoesyraderivat | |
| NO153137C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte pyrido(1,2-a)pyrimidiner. | |
| NO136795C (no) | Analogifremgangsm}te for fremstilling av terapeutisk aktive indoliner | |
| NO139439C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive pyrazolon-(5)-forbindelser | |
| AR192347A1 (es) | Procedimiento para la preparacion de 3-amino-imidazo(1,5-a)piridinas | |
| NO139735C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimido(4,5-b)kinolin-4(3h)-on-derivater | |
| NO136574C (no) | Analogifremgangsm}te for fremstilling av terapeutisk aktive pyrimidinderivater. |