IL40895A0 - Pyrazolo(1,5a)pyrimidines and their preparation - Google Patents
Pyrazolo(1,5a)pyrimidines and their preparationInfo
- Publication number
- IL40895A0 IL40895A0 IL40895A IL4089572A IL40895A0 IL 40895 A0 IL40895 A0 IL 40895A0 IL 40895 A IL40895 A IL 40895A IL 4089572 A IL4089572 A IL 4089572A IL 40895 A0 IL40895 A0 IL 40895A0
- Authority
- IL
- Israel
- Prior art keywords
- pyrazolo
- pyrimidines
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20653871A | 1971-12-09 | 1971-12-09 | |
| US245870A US3925385A (en) | 1972-04-20 | 1972-04-20 | 6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines |
| US27346572A | 1972-07-20 | 1972-07-20 | |
| US29984072A | 1972-10-24 | 1972-10-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL40895A0 true IL40895A0 (en) | 1973-01-30 |
| IL40895A IL40895A (en) | 1976-12-31 |
Family
ID=27498614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL40895A IL40895A (en) | 1971-12-09 | 1972-11-22 | Pyrazolo(1,5a)pyrimidines and their preparation |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS4864097A (en) |
| BE (1) | BE792533A (en) |
| BG (1) | BG22401A3 (en) |
| CH (1) | CH603652A5 (en) |
| DD (1) | DD104530A5 (en) |
| DE (1) | DE2257547A1 (en) |
| GB (1) | GB1412017A (en) |
| HU (1) | HU168530B (en) |
| IE (1) | IE37189B1 (en) |
| IL (1) | IL40895A (en) |
| LU (1) | LU66597A1 (en) |
| NL (1) | NL7216539A (en) |
| NO (1) | NO137012C (en) |
| RO (1) | RO62762A (en) |
| SE (1) | SE398751B (en) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281000A (en) * | 1979-07-09 | 1981-07-28 | American Cyanamid Company | Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents |
| AU557300B2 (en) * | 1982-03-16 | 1986-12-18 | Farmitalia Carlo Erba S.P.A. | Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation |
| ZA831407B (en) * | 1982-03-25 | 1983-11-30 | Erba Farmitalia | Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation |
| NZ208554A (en) * | 1983-06-23 | 1987-06-30 | American Cyanamid Co | (aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions |
| DE3533050A1 (en) * | 1985-09-17 | 1987-03-26 | Basf Ag | 7-AMINO-AZOLO (1,5-A) PYRIMIDINE, METHOD FOR THE PRODUCTION THEREOF AND FUNGICIDES CONTAINING THEM, OR THEIR USE AS FUNGICIDES |
| CA1330079C (en) * | 1988-10-13 | 1994-06-07 | Michihiko Tsujitani | Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same |
| KR100191774B1 (en) * | 1991-04-22 | 1999-06-15 | 오스카 아끼히꼬 | Pyrazolo(1,5-alpha)pyrimidine derivatives and anti-inflammatory agent containing them |
| DE4333705C2 (en) * | 1993-10-02 | 2003-10-30 | Guenter Ege | Arylmethyl-substituted pyrazolo-azines, in particular 3-arylmethylpyrazolo [1,5-a] pyrimidines and process for the preparation of 8-arylmethylpyrazolo [5,1-c] [1,2,4] triazines |
| KR100315837B1 (en) * | 1994-06-21 | 2002-02-28 | 고리 히데아끼 | PYRAZOLO[1,5-a]PYRAMIDINE DERIVATIVE |
| US5843951A (en) * | 1995-09-28 | 1998-12-01 | Otsuka Pharmaceutical Factory Inc. | Analgesic composition of pyrazolo(1,5-A) pyrimidines |
| FR2771631B1 (en) | 1997-12-03 | 2001-02-02 | Oreal | KERATINIC FIBER DYE COMPOSITIONS CONTAINING 3-AMINO PYRAZOLO- [1,5-A] -PYRIMIDINES, DYEING PROCESS, NEW 3-AMINO PYRAZOLO- [1,5-A] -PYRIMIDINES AND THE PROCESS FOR THE PREPARATION |
| AU2003263071B2 (en) * | 2002-09-04 | 2007-03-15 | Merck Sharp & Dohme Llc | Pyrazolopyrimidines as cyclin-dependent kinase inhibitors |
| US7119200B2 (en) * | 2002-09-04 | 2006-10-10 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| US7161003B1 (en) | 2002-09-04 | 2007-01-09 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| ES2222813B1 (en) * | 2003-07-24 | 2005-12-16 | Ferrer Internacional, S.A. | N- (3- (3-SUBSTITUTES-PIRAZOLO (1,5-A) PIRIMIDIN-7-IL) -PENYL) -SULPHONAMIDS AND RELATED COMPOSITIONS AND METHODS |
| TWI252851B (en) * | 2003-07-24 | 2006-04-11 | Ferrer Int | 7-substituted 3-nitro-pyrazolo[1,5-a]pyrimidines and compositions and methods related thereto |
| EP2989106B1 (en) | 2013-04-25 | 2016-12-14 | Beigene, Ltd. | Fused heterocyclic compounds as protein kinase inhibitors |
| ES2792183T3 (en) | 2013-09-13 | 2020-11-10 | Beigene Switzerland Gmbh | Anti-PD1 antibodies and their use as therapeutic and diagnostic products |
| CN110156892B (en) | 2014-07-03 | 2023-05-16 | 百济神州有限公司 | anti-PD-L1 antibodies and their use as therapeutic and diagnostic agents |
| CN109475536B (en) | 2016-07-05 | 2022-05-27 | 百济神州有限公司 | Combination of a PD-l antagonist and a RAF inhibitor for the treatment of cancer |
| CN109563099B (en) | 2016-08-16 | 2023-02-03 | 百济神州有限公司 | Crystal form of compound, preparation and application thereof |
| WO2018033135A1 (en) | 2016-08-19 | 2018-02-22 | Beigene, Ltd. | Use of a combination comprising a btk inhibitor for treating cancers |
| TWI774726B (en) | 2017-01-25 | 2022-08-21 | 英屬開曼群島商百濟神州有限公司 | Crystalline forms of (s)-7-(1-(but-2-ynoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof |
| CN110799543A (en) | 2017-06-26 | 2020-02-14 | 百济神州有限公司 | Immunotherapy of hepatocellular carcinoma |
| US11377449B2 (en) | 2017-08-12 | 2022-07-05 | Beigene, Ltd. | BTK inhibitors with improved dual selectivity |
| CN111801334B (en) | 2017-11-29 | 2023-06-09 | 百济神州瑞士有限责任公司 | Treatment of indolent or invasive B-cell lymphomas using combinations comprising BTK inhibitors |
| US11786531B1 (en) | 2022-06-08 | 2023-10-17 | Beigene Switzerland Gmbh | Methods of treating B-cell proliferative disorder |
-
0
- BE BE792533D patent/BE792533A/en unknown
-
1972
- 1972-11-21 IE IE1612/72A patent/IE37189B1/en unknown
- 1972-11-22 IL IL40895A patent/IL40895A/en unknown
- 1972-11-23 DE DE2257547A patent/DE2257547A1/en active Pending
- 1972-12-01 GB GB5558772A patent/GB1412017A/en not_active Expired
- 1972-12-05 SE SE7215829A patent/SE398751B/en unknown
- 1972-12-05 LU LU66597A patent/LU66597A1/xx unknown
- 1972-12-06 NL NL7216539A patent/NL7216539A/xx not_active Application Discontinuation
- 1972-12-06 NO NO4476/72A patent/NO137012C/en unknown
- 1972-12-06 CH CH1775172A patent/CH603652A5/xx not_active IP Right Cessation
- 1972-12-07 DD DD167370A patent/DD104530A5/xx unknown
- 1972-12-08 HU HUIE548A patent/HU168530B/hu unknown
- 1972-12-09 BG BG22071A patent/BG22401A3/xx unknown
- 1972-12-09 JP JP47123877A patent/JPS4864097A/ja active Pending
- 1972-12-09 RO RO7200073093A patent/RO62762A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LU66597A1 (en) | 1973-03-15 |
| IL40895A (en) | 1976-12-31 |
| BG22401A3 (en) | 1977-02-20 |
| CH603652A5 (en) | 1978-08-31 |
| JPS4864097A (en) | 1973-09-05 |
| IE37189L (en) | 1973-06-09 |
| RO62762A (en) | 1978-05-15 |
| HU168530B (en) | 1976-05-28 |
| SE398751B (en) | 1978-01-16 |
| GB1412017A (en) | 1975-10-29 |
| BE792533A (en) | 1973-06-08 |
| NL7216539A (en) | 1973-06-13 |
| DE2257547A1 (en) | 1973-06-14 |
| NO137012B (en) | 1977-09-05 |
| DD104530A5 (en) | 1974-03-12 |
| IE37189B1 (en) | 1977-05-25 |
| NO137012C (en) | 1977-12-14 |
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