NL930062I2 - 4-Amino-2- (piperazin-1-yl or homopiperazin-1-yl) quinazolines, and a method of preparing such a compound and a method of preparing pharmaceutical compositions using these compounds. - Google Patents

4-Amino-2- (piperazin-1-yl or homopiperazin-1-yl) quinazolines, and a method of preparing such a compound and a method of preparing pharmaceutical compositions using these compounds.

Info

Publication number: NL930062I2
Authority: NL; Netherlands
Prior art keywords: preparing; homopiperazin; quinazolines; piperazin; amino
Prior art date: 1977-11-05

Application number

NL930062C

Other languages

Dutch (nl)

Other versions

NL930062I1 (en

Original Assignee

Pifzer Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-11-05

Filing date

1993-06-11

Publication date

1993-11-16

1993-06-11 Application filed by Pifzer Corp filed Critical Pifzer Corp

1993-09-01 Publication of NL930062I1 publication Critical patent/NL930062I1/en

1993-11-16 Publication of NL930062I2 publication Critical patent/NL930062I2/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

NL930062C 1977-11-05 1993-06-11 4-Amino-2- (piperazin-1-yl or homopiperazin-1-yl) quinazolines, and a method of preparing such a compound and a method of preparing pharmaceutical compositions using these compounds. NL930062I2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB4612877		1977-11-05

Publications (2)

Publication Number	Publication Date
NL930062I1 NL930062I1 (en)	1993-09-01
NL930062I2 true NL930062I2 (en)	1993-11-16

Family

ID=10439957

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NLAANVRAGE7810909,A NL174549C (en)	1977-11-05	1978-11-02	4-AMINO-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) CHINAZOLINES, A METHOD FOR PREPARING SUCH A COMPOUND AND A METHOD FOR PREPARING PHARMACEUTICAL PREPARATIONS USING THESE COMPOUNDS.
NL930062C NL930062I2 (en)	1977-11-05	1993-06-11	4-Amino-2- (piperazin-1-yl or homopiperazin-1-yl) quinazolines, and a method of preparing such a compound and a method of preparing pharmaceutical compositions using these compounds.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
NLAANVRAGE7810909,A NL174549C (en)	1977-11-05	1978-11-02	4-AMINO-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) CHINAZOLINES, A METHOD FOR PREPARING SUCH A COMPOUND AND A METHOD FOR PREPARING PHARMACEUTICAL PREPARATIONS USING THESE COMPOUNDS.

Country Status (36)

Country	Link
JP (1)	JPS5498792A (en)
AR (2)	AR219562A1 (en)
AT (1)	AT365186B (en)
AU (1)	AU509329B2 (en)
BE (1)	BE871771A (en)
CA (1)	CA1088059A (en)
CH (1)	CH643255A5 (en)
CS (2)	CS207671B2 (en)
DD (1)	DD139850A5 (en)
DE (1)	DE2847623C2 (en)
DK (1)	DK154082C (en)
EG (1)	EG13594A (en)
ES (2)	ES474805A1 (en)
FI (1)	FI64366C (en)
FR (1)	FR2407929A1 (en)
GR (1)	GR81514B (en)
HK (1)	HK94284A (en)
HU (1)	HU176306B (en)
IE (1)	IE47888B1 (en)
IL (1)	IL55857A (en)
IN (1)	IN148828B (en)
IT (1)	IT1100919B (en)
KE (1)	KE3350A (en)
LU (2)	LU80470A1 (en)
MY (1)	MY8500286A (en)
NL (2)	NL174549C (en)
NO (1)	NO150158C (en)
NZ (1)	NZ188813A (en)
PH (1)	PH13966A (en)
PL (2)	PL119586B1 (en)
PT (1)	PT68735A (en)
SE (1)	SE437518B (en)
SU (1)	SU816403A3 (en)
UA (1)	UA8324A1 (en)
YU (2)	YU40204B (en)
ZA (1)	ZA786184B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1985004658A1 (en) *	1984-04-04	1985-10-24	Takeda Chemical Industries, Ltd.	1,5-benzoxathiepine derivatives and their preparation
WO1985002617A1 (en) *	1983-12-14	1985-06-20	Takeda Chemical Industries. Ltd.	1,5-benzoxathiepin derivatives and process for their preparation
WO1986002644A1 (en) *	1984-11-01	1986-05-09	Takeda Chemical Industries, Ltd.	1,5-benzoxathiepin derivatives and process for their preparation
EP0849264A1 (en) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Novel polymorphic form of doxazosin mesylate (form I)
EP0849266B8 (en) *	1996-12-20	2007-10-03	Heumann PCS GmbH	Novel polymorphic form of doxazosin mesylate (form III)
EP0849265A1 (en) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Novel polymorphic form of doxazosin mesylate (form II)
TW448155B (en) *	1999-03-29	2001-08-01	Dev Center Biotechnology	Method for producing amide compounds and quinazolin derivatives
EP1403263B1 (en) *	2002-09-27	2005-06-22	Council of Scientific and Industrial Research	Process for the preparation of N-(2,3-dihydrobenzo 1,4 dioxin-2-carbonyl) piperazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3663706A (en) *	1969-09-29	1972-05-16	Pfizer	Use of 2,4-diaminoquinazolines as hypotensive agents
US3669968A (en) *	1970-05-21	1972-06-13	Pfizer	Trialkoxy quinazolines

1978
- 1978-09-27 DK DK428678A patent/DK154082C/en active
- 1978-10-03 IN IN712/DEL/78A patent/IN148828B/en unknown
- 1978-10-24 CA CA314,027A patent/CA1088059A/en not_active Expired
- 1978-10-24 PH PH21726A patent/PH13966A/en unknown
- 1978-10-31 SU SU782679598A patent/SU816403A3/en active
- 1978-10-31 UA UA2679598A patent/UA8324A1/en unknown
- 1978-11-02 JP JP13569578A patent/JPS5498792A/en active Granted
- 1978-11-02 PT PT68735A patent/PT68735A/en unknown
- 1978-11-02 NL NLAANVRAGE7810909,A patent/NL174549C/en not_active IP Right Cessation
- 1978-11-02 AR AR274321A patent/AR219562A1/en active
- 1978-11-02 CS CS787166A patent/CS207671B2/en unknown
- 1978-11-02 FI FI783347A patent/FI64366C/en not_active IP Right Cessation
- 1978-11-02 NZ NZ188813A patent/NZ188813A/en unknown
- 1978-11-02 AT AT0784378A patent/AT365186B/en not_active IP Right Cessation
- 1978-11-02 HU HU78PI648A patent/HU176306B/en unknown
- 1978-11-02 IL IL55857A patent/IL55857A/en unknown
- 1978-11-02 SE SE7811382A patent/SE437518B/en not_active IP Right Cessation
- 1978-11-02 DE DE2847623A patent/DE2847623C2/en not_active Expired
- 1978-11-02 GR GR57562A patent/GR81514B/el unknown
- 1978-11-02 CH CH1132178A patent/CH643255A5/en not_active IP Right Cessation
- 1978-11-02 YU YU2553/78A patent/YU40204B/en unknown
- 1978-11-02 ZA ZA00786184A patent/ZA786184B/en unknown
- 1978-11-03 NO NO783705A patent/NO150158C/en unknown
- 1978-11-03 BE BE191544A patent/BE871771A/en not_active IP Right Cessation
- 1978-11-03 FR FR7831126A patent/FR2407929A1/en active Granted
- 1978-11-03 IE IE2179/78A patent/IE47888B1/en active Protection Beyond IP Right Term
- 1978-11-03 IT IT29434/78A patent/IT1100919B/en active Protection Beyond IP Right Term
- 1978-11-03 PL PL1978210681A patent/PL119586B1/en unknown
- 1978-11-03 DD DD78208868A patent/DD139850A5/en unknown
- 1978-11-03 AU AU41322/78A patent/AU509329B2/en not_active Expired
- 1978-11-03 PL PL1978216980A patent/PL119419B1/en unknown
- 1978-11-03 ES ES474805A patent/ES474805A1/en not_active Expired
- 1978-11-03 LU LU80470A patent/LU80470A1/en unknown
- 1978-11-04 EG EG641/78A patent/EG13594A/en active
1979
- 1979-04-30 ES ES480121A patent/ES8308559A1/en not_active Expired
- 1979-10-18 AR AR278545A patent/AR223015A1/en active
1983
- 1983-02-17 YU YU386/83A patent/YU40419B/en unknown
- 1983-11-21 KE KE3350A patent/KE3350A/en unknown
1984
- 1984-11-29 HK HK942/84A patent/HK94284A/en not_active IP Right Cessation
1985
- 1985-12-30 MY MY286/85A patent/MY8500286A/en unknown
1991
- 1991-11-22 CS CS913544A patent/CS354491A3/en unknown
1993
- 1993-06-11 NL NL930062C patent/NL930062I2/en unknown
- 1993-06-24 LU LU88331C patent/LU88331I2/en unknown

Also Published As

Publication number	Publication date
HU176306B (en)	1981-01-28
LU80470A1 (en)	1980-06-05
PL210681A1 (en)	1979-11-05
IL55857A0 (en)	1979-01-31
SU816403A3 (en)	1981-03-23
AT365186B (en)	1981-12-28
IT1100919B (en)	1985-09-28
NL174549B (en)	1984-02-01
AU509329B2 (en)	1980-05-08
DK154082C (en)	1989-02-27
NL7810909A (en)	1979-05-08
ES480121A0 (en)	1980-07-16
PH13966A (en)	1980-11-12
SE437518B (en)	1985-03-04
YU40204B (en)	1985-08-31
DK154082B (en)	1988-10-10
FI783347A (en)	1979-05-06
NZ188813A (en)	1980-10-08
CH643255A5 (en)	1984-05-30
LU88331I2 (en)	1994-05-04
SE7811382L (en)	1979-05-06
NO783705L (en)	1979-05-08
IE47888B1 (en)	1984-07-11
DE2847623A1 (en)	1979-05-23
FI64366B (en)	1983-07-29
EG13594A (en)	1982-03-31
ZA786184B (en)	1979-10-31
CS354491A3 (en)	1992-06-17
ES474805A1 (en)	1980-01-16
NL930062I1 (en)	1993-09-01
FR2407929A1 (en)	1979-06-01
FR2407929B1 (en)	1981-02-27
YU38683A (en)	1983-06-30
GR81514B (en)	1984-12-11
ES8308559A1 (en)	1980-07-16
PL119586B1 (en)	1982-01-30
JPS5625233B2 (en)	1981-06-11
BE871771A (en)	1979-05-03
IL55857A (en)	1982-07-30
ATA784378A (en)	1981-05-15
UA8324A1 (en)	1996-03-29
IE782179L (en)	1979-05-05
AU4132278A (en)	1979-05-17
FI64366C (en)	1983-11-10
PL119419B1 (en)	1981-12-31
NL174549C (en)	1984-07-02
YU255378A (en)	1983-06-30
DE2847623C2 (en)	1983-06-01
CS207671B2 (en)	1981-08-31
NO150158C (en)	1984-08-29
AR223015A1 (en)	1981-07-15
CA1088059A (en)	1980-10-21
MY8500286A (en)	1985-12-31
NO150158B (en)	1984-05-21
JPS5498792A (en)	1979-08-03
DK428678A (en)	1979-05-06
IT7829434A0 (en)	1978-11-03
PT68735A (en)	1978-12-01
IN148828B (en)	1981-06-27
AR219562A1 (en)	1980-08-29
DD139850A5 (en)	1980-01-23
KE3350A (en)	1983-12-16
HK94284A (en)	1984-12-07
YU40419B (en)	1985-12-31

Publication	Publication Date	Title
IT7831028A0 (en)	1978-12-19	13-HALO-DERIVATIVES AND 13-DEOXY-DERIVATIVES OF COMPOUNDS C-076.
NL7810520A (en)	1979-04-24	NEW 2,6-DIAMINONE BULARINS, AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS.
IL55845A (en)	1982-07-30	Quinazoline derivatives,their preparation and pharmaceutical compositions containing them
NL7804230A (en)	1978-11-07	N-ALKYL-N-ACYL DERIVATIVES OF THIENAMYCIN, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL PREPARATIONS.
IL56017A (en)	1983-03-31	5-cyano-prostacyclin derivatives,their manufacture and pharmaceutical compositions containing them
NL930062I2 (en)	1993-11-16	4-Amino-2- (piperazin-1-yl or homopiperazin-1-yl) quinazolines, and a method of preparing such a compound and a method of preparing pharmaceutical compositions using these compounds.
NL7806528A (en)	1978-12-19	PREPARATION OF SALPETERIC ACID.
NL7803165A (en)	1978-09-27	NEW 7-AMINOTHIAZOLYLACETAMIDOCEPHALOSPORANIC ACID COMPOUNDS, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS.
NL7804550A (en)	1978-10-31	METHOD OF PREPARATION OF UREA DERIVATIVES.
NL7807974A (en)	1979-01-30	THIATETRAHYDROFURAN COMPOUNDS, AND METHOD OF PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING SUCH COMPOUNDS.
NL188645B (en)	1992-03-16	1-AZAXANTHON-3-CARBONIC ACID COMPOUNDS AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS.
IT7821686A0 (en)	1978-03-28	PHARMACEUTICAL COMPOSITION.
NL7801887A (en)	1978-08-24	NEW 20,21-DINOREBURNAMENINE COMPOUNDS, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS.
NL174345C (en)	1984-06-01	ACID ALKALICITRATE, METHOD OF PREPARING THE SAME AND THERAPEUTIC PREPARATION.
IT7829133A0 (en)	1978-10-26	DERIVATIVES OF 6-OXYGENATE-3,20-DIOXOPREGNAN, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
IT1098005B (en)	1985-08-31	ORGANOSTAGNO COMPOUNDS, THEIR PREPARATION AND USE
IL53926A0 (en)	1978-04-30	New oxadiazolopyrimidine derivatives, their manufacture and pharmaceutical compositions containing them
IT1109266B (en)	1985-12-16	BISOTITUITED PIPERAZINE PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IT7827871A0 (en)	1978-09-20	SERINOL PREPARATION PROCEDURE.
NL7803448A (en)	1978-10-03	NEW BENZOTHIADIAZINE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS.
IL54328A0 (en)	1978-06-15	Novel quinazoline derivatives, their manufacture and pharmaceutical compositions containing them
NL7801464A (en)	1978-08-10	PHARMACEUTICAL COMPOSITIONS.
NL7807679A (en)	1979-01-23	NEW BENZAMIDINE DERIVATIVES, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
PH14064A (en)	1981-01-26	Phenylgycine derivatives,pharmaceutical compositions and method of use
IT7828611A0 (en)	1978-10-10	PROCEDURE FOR THE PREPARATION OF NITROPHENYLACETYLENE PRECURSORS.