NL8302859A - Desoxyuridine derivaten en werkwijzen voor het bereiden van deze derivaten en hun toepassing als farmaceutica. - Google Patents

Desoxyuridine derivaten en werkwijzen voor het bereiden van deze derivaten en hun toepassing als farmaceutica. Download PDF

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Publication number
NL8302859A
NL8302859A NL8302859A NL8302859A NL8302859A NL 8302859 A NL8302859 A NL 8302859A NL 8302859 A NL8302859 A NL 8302859A NL 8302859 A NL8302859 A NL 8302859A NL 8302859 A NL8302859 A NL 8302859A
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NL
Netherlands
Prior art keywords
group
compound
acid addition
addition salt
formula
Prior art date
Application number
NL8302859A
Other languages
English (en)
Dutch (nl)
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NL8302859A publication Critical patent/NL8302859A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NL8302859A 1982-08-17 1983-08-15 Desoxyuridine derivaten en werkwijzen voor het bereiden van deze derivaten en hun toepassing als farmaceutica. NL8302859A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH492282 1982-08-17
CH492282 1982-08-17

Publications (1)

Publication Number Publication Date
NL8302859A true NL8302859A (nl) 1984-03-16

Family

ID=4284858

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8302859A NL8302859A (nl) 1982-08-17 1983-08-15 Desoxyuridine derivaten en werkwijzen voor het bereiden van deze derivaten en hun toepassing als farmaceutica.

Country Status (16)

Country Link
JP (1) JPS5953499A (da)
AU (1) AU1800483A (da)
BE (1) BE897516A (da)
DE (1) DE3390162T1 (da)
DK (1) DK372283A (da)
ES (1) ES8604943A1 (da)
FI (1) FI832884A (da)
FR (1) FR2531962B1 (da)
GB (1) GB2125401B (da)
IL (1) IL69497A0 (da)
IT (1) IT1169765B (da)
NL (1) NL8302859A (da)
PT (1) PT77209B (da)
SE (1) SE8304408L (da)
WO (1) WO1984000759A1 (da)
ZA (1) ZA836072B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526988A (en) * 1983-03-10 1985-07-02 Eli Lilly And Company Difluoro antivirals and intermediate therefor
CA1295998C (en) * 1985-07-29 1992-02-18 Sai P. Sunkara Nucleosides and their use as antineoplastic agents
SE8605503D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel medicinal use
US5215971A (en) * 1986-12-19 1993-06-01 Medivir Ab Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides
US5215970A (en) * 1987-04-16 1993-06-01 Medivir Ab Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds
US4863927A (en) * 1987-05-11 1989-09-05 Merck & Co., Inc. 1-(2-hydroxymethyl)cycloalkylmethyl)-5-substituted uracils
US5401838A (en) * 1992-06-22 1995-03-28 Eli Lilly And Company Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
MX9303708A (es) * 1992-06-22 1994-05-31 Lilly Co Eli Proceso de glucosilacion anionica estereoselectiva para preparar 2'-desoxifluoro-beta nucleosidos.
US5821357A (en) * 1992-06-22 1998-10-13 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoropurine and triazole nucleosides
US5426183A (en) * 1992-06-22 1995-06-20 Eli Lilly And Company Catalytic stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5594124A (en) * 1992-06-22 1997-01-14 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-Deoxy-2',2'-difluoropyrimidine nucleosides and 2'-deoxy-2'-fluoropyrimidine nucleosides and intermediates thereof
US5606048A (en) * 1992-06-22 1997-02-25 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-Deoxy-2', 2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5371210A (en) * 1992-06-22 1994-12-06 Eli Lilly And Company Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5424416A (en) * 1993-08-25 1995-06-13 Eli Lilly And Company Process for preparation of 2-deoxy-2,2-difluoro-D-ribofuranosyl-3,5-hydroxy protected-1-alkyl and aryl sulfonates and their use in preparation of 2',2'-difluoro-2'-deoxy nucleosides
SE9701219D0 (sv) * 1997-04-04 1997-04-04 Astra Pharma Prod New compounds
WO2003018030A1 (en) * 2001-08-24 2003-03-06 Koronis Pharmaceuticals, Inc. Mutagenic nucleoside analogs for the treatment of viral disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3709874A (en) * 1970-03-19 1973-01-09 Syntex Corp 1-beta-d-arabinofuranosyl cytosine derivatives and methods of preparing
GB1601020A (en) * 1978-04-24 1981-10-21 Stichting Grega Vzw 2'-deoxy-5 (2-halogenovinyl)-uridines
GB2060604B (en) * 1979-10-03 1983-11-23 Univ Birmingham And Stichting E15-(2-halogenovinyl)-2'-deoxycytidines
DE3002197A1 (de) * 1980-01-22 1981-07-23 Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen 5-alkylsubstituierte pyrimidin-nukleoside, verfahren zu deren herstellung und daraus hergestellte virostatische und cytostatische mittel
DE3010399A1 (de) * 1980-03-18 1981-09-24 Kailash Kumar Dr. 2359 Lentföhrden Gauri Verwendung von 5-haloalkyl-pyrimidin-nukleosiden als virostatika und cytostatika
HU183567B (en) * 1981-09-07 1984-05-28 Mta Koezponti Kemiai Kutato In Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof

Also Published As

Publication number Publication date
GB2125401A (en) 1984-03-07
IT1169765B (it) 1987-06-03
ES8604943A1 (es) 1986-02-16
GB2125401B (en) 1985-10-16
PT77209A (en) 1983-09-01
SE8304408L (sv) 1984-02-18
ES524997A0 (es) 1986-02-16
BE897516A (fr) 1984-02-13
ZA836072B (en) 1985-03-27
WO1984000759A1 (en) 1984-03-01
FI832884A (fi) 1984-02-18
DE3390162T1 (de) 1985-02-21
SE8304408D0 (sv) 1983-08-15
IT8322565A0 (it) 1983-08-16
AU1800483A (en) 1984-02-23
DK372283D0 (da) 1983-08-15
FR2531962A1 (fr) 1984-02-24
GB8321880D0 (en) 1983-09-14
FR2531962B1 (fr) 1986-11-14
DK372283A (da) 1984-02-18
IL69497A0 (en) 1983-11-30
JPS5953499A (ja) 1984-03-28
PT77209B (en) 1986-03-18
FI832884A0 (fi) 1983-08-10

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BV The patent application has lapsed