IT8322565A0 - Derivati della desossiuridina, loro preparazione e loro impiego come medicamenti. - Google Patents

Derivati della desossiuridina, loro preparazione e loro impiego come medicamenti.

Info

Publication number: IT8322565A0
Authority: IT; Italy
Prior art keywords: desoxyuridine; medicines; derivatives; preparation; desoxyuridine derivatives
Prior art date: 1982-08-17

Application number

IT8322565A

Other languages

English (en)

Other versions

IT1169765B (it

Inventor

Herfried Griengl

Erich Wanek

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-08-17

Filing date

1983-08-16

Publication date

1983-08-16

1983-08-16 Application filed by Sandoz Ag filed Critical Sandoz Ag

1983-08-16 Publication of IT8322565A0 publication Critical patent/IT8322565A0/it

1987-06-03 Application granted granted Critical

1987-06-03 Publication of IT1169765B publication Critical patent/IT1169765B/it

Links

MXHRCPNRJAMMIM-SHYZEUOFSA-N 2'-deoxyuridine Chemical class C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 MXHRCPNRJAMMIM-SHYZEUOFSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

IT22565/83A 1982-08-17 1983-08-16 Derivati della desossiuridina, loro preparazione e loro impiego come medicamenti IT1169765B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH492282		1982-08-17

Publications (2)

Publication Number	Publication Date
IT8322565A0 true IT8322565A0 (it)	1983-08-16
IT1169765B IT1169765B (it)	1987-06-03

Family

ID=4284858

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT22565/83A IT1169765B (it)	1982-08-17	1983-08-16	Derivati della desossiuridina, loro preparazione e loro impiego come medicamenti

Country Status (16)

Country	Link
JP (1)	JPS5953499A (it)
AU (1)	AU1800483A (it)
BE (1)	BE897516A (it)
DE (1)	DE3390162T1 (it)
DK (1)	DK372283A (it)
ES (1)	ES8604943A1 (it)
FI (1)	FI832884A (it)
FR (1)	FR2531962B1 (it)
GB (1)	GB2125401B (it)
IL (1)	IL69497A0 (it)
IT (1)	IT1169765B (it)
NL (1)	NL8302859A (it)
PT (1)	PT77209B (it)
SE (1)	SE8304408L (it)
WO (1)	WO1984000759A1 (it)
ZA (1)	ZA836072B (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4526988A (en) *	1983-03-10	1985-07-02	Eli Lilly And Company	Difluoro antivirals and intermediate therefor
CA1295998C (en) *	1985-07-29	1992-02-18	Sai P. Sunkara	Nucleosides and their use as antineoplastic agents
SE8605503D0 (sv) *	1986-12-19	1986-12-19	Astra Laekemedel Ab	Novel medicinal use
US5215971A (en) *	1986-12-19	1993-06-01	Medivir Ab	Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides
US5215970A (en) *	1987-04-16	1993-06-01	Medivir Ab	Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds
US4863927A (en) *	1987-05-11	1989-09-05	Merck & Co., Inc.	1-(2-hydroxymethyl)cycloalkylmethyl)-5-substituted uracils
US5401838A (en) *	1992-06-22	1995-03-28	Eli Lilly And Company	Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
MX9303708A (es) *	1992-06-22	1994-05-31	Lilly Co Eli	Proceso de glucosilacion anionica estereoselectiva para preparar 2'-desoxifluoro-beta nucleosidos.
US5821357A (en) *	1992-06-22	1998-10-13	Eli Lilly And Company	Stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoropurine and triazole nucleosides
US5426183A (en) *	1992-06-22	1995-06-20	Eli Lilly And Company	Catalytic stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5594124A (en) *	1992-06-22	1997-01-14	Eli Lilly And Company	Stereoselective glycosylation process for preparing 2'-Deoxy-2',2'-difluoropyrimidine nucleosides and 2'-deoxy-2'-fluoropyrimidine nucleosides and intermediates thereof
US5606048A (en) *	1992-06-22	1997-02-25	Eli Lilly And Company	Stereoselective glycosylation process for preparing 2'-Deoxy-2', 2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5371210A (en) *	1992-06-22	1994-12-06	Eli Lilly And Company	Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5424416A (en) *	1993-08-25	1995-06-13	Eli Lilly And Company	Process for preparation of 2-deoxy-2,2-difluoro-D-ribofuranosyl-3,5-hydroxy protected-1-alkyl and aryl sulfonates and their use in preparation of 2',2'-difluoro-2'-deoxy nucleosides
SE9701219D0 (sv) *	1997-04-04	1997-04-04	Astra Pharma Prod	New compounds
WO2003018030A1 (en) *	2001-08-24	2003-03-06	Koronis Pharmaceuticals, Inc.	Mutagenic nucleoside analogs for the treatment of viral disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3709874A (en) *	1970-03-19	1973-01-09	Syntex Corp	1-beta-d-arabinofuranosyl cytosine derivatives and methods of preparing
GB1601020A (en) *	1978-04-24	1981-10-21	Stichting Grega Vzw	2'-deoxy-5 (2-halogenovinyl)-uridines
GB2060604B (en) *	1979-10-03	1983-11-23	Univ Birmingham And Stichting	E15-(2-halogenovinyl)-2'-deoxycytidines
DE3002197A1 (de) *	1980-01-22	1981-07-23	Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen	5-alkylsubstituierte pyrimidin-nukleoside, verfahren zu deren herstellung und daraus hergestellte virostatische und cytostatische mittel
DE3010399A1 (de) *	1980-03-18	1981-09-24	Kailash Kumar Dr. 2359 Lentföhrden Gauri	Verwendung von 5-haloalkyl-pyrimidin-nukleosiden als virostatika und cytostatika
HU183567B (en) *	1981-09-07	1984-05-28	Mta Koezponti Kemiai Kutato In	Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof

1983
- 1983-08-10 FI FI832884A patent/FI832884A/fi not_active Application Discontinuation
- 1983-08-10 FR FR8313242A patent/FR2531962B1/fr not_active Expired
- 1983-08-11 BE BE0/108521A patent/BE897516A/fr not_active IP Right Cessation
- 1983-08-12 WO PCT/EP1983/000219 patent/WO1984000759A1/de active Application Filing
- 1983-08-12 DE DE19833390162 patent/DE3390162T1/de not_active Withdrawn
- 1983-08-15 DK DK372283A patent/DK372283A/da not_active Application Discontinuation
- 1983-08-15 AU AU18004/83A patent/AU1800483A/en not_active Abandoned
- 1983-08-15 SE SE8304408A patent/SE8304408L/xx not_active Application Discontinuation
- 1983-08-15 IL IL69497A patent/IL69497A0/xx unknown
- 1983-08-15 GB GB08321880A patent/GB2125401B/en not_active Expired
- 1983-08-15 NL NL8302859A patent/NL8302859A/nl not_active Application Discontinuation
- 1983-08-16 IT IT22565/83A patent/IT1169765B/it active
- 1983-08-16 JP JP58150111A patent/JPS5953499A/ja active Pending
- 1983-08-16 PT PT77209A patent/PT77209B/pt unknown
- 1983-08-17 ZA ZA836072A patent/ZA836072B/xx unknown
- 1983-08-17 ES ES524997A patent/ES8604943A1/es not_active Expired

Also Published As

Publication number	Publication date
NL8302859A (nl)	1984-03-16
GB2125401A (en)	1984-03-07
IT1169765B (it)	1987-06-03
ES8604943A1 (es)	1986-02-16
GB2125401B (en)	1985-10-16
PT77209A (en)	1983-09-01
SE8304408L (sv)	1984-02-18
ES524997A0 (es)	1986-02-16
BE897516A (fr)	1984-02-13
ZA836072B (en)	1985-03-27
WO1984000759A1 (en)	1984-03-01
FI832884A (fi)	1984-02-18
DE3390162T1 (de)	1985-02-21
SE8304408D0 (sv)	1983-08-15
AU1800483A (en)	1984-02-23
DK372283D0 (da)	1983-08-15
FR2531962A1 (fr)	1984-02-24
GB8321880D0 (en)	1983-09-14
FR2531962B1 (fr)	1986-11-14
DK372283A (da)	1984-02-18
IL69497A0 (en)	1983-11-30
JPS5953499A (ja)	1984-03-28
PT77209B (en)	1986-03-18
FI832884A0 (fi)	1983-08-10

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