MY103801A - Dideoxydidehydrocarbocyclic nucleosides - Google Patents

Dideoxydidehydrocarbocyclic nucleosides

Info

Publication number: MY103801A
Authority: MY; Malaysia
Prior art keywords: dideoxydidehydrocarbocyclic; nucleosides; compounds; nrr1; formula
Prior art date: 1988-01-20

Application number

MYPI89000064A

Other languages

English (en)

Inventor

Vince Robert

Hua Mei

Leslie Myers Peter

Storer Richard

Original Assignee

Univ Minnesota

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-20

Filing date

1989-01-19

Publication date

1993-09-30

1988-01-20 Priority claimed from US07/146,252 external-priority patent/US4916224A/en

1988-09-07 Priority claimed from GB888821011A external-priority patent/GB8821011D0/en

1988-12-05 Priority claimed from US07/278,652 external-priority patent/US4931559A/en

1989-01-19 Application filed by Univ Minnesota filed Critical Univ Minnesota

1993-09-30 Publication of MY103801A publication Critical patent/MY103801A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

MYPI89000064A 1988-01-20 1989-01-19 Dideoxydidehydrocarbocyclic nucleosides MY103801A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US07/146,252 US4916224A (en)	1988-01-20	1988-01-20	Dideoxycarbocyclic nucleosides
GB888821011A GB8821011D0 (en)	1988-09-07	1988-09-07	Chemical compounds
US07/278,652 US4931559A (en)	1988-01-20	1988-12-05	Optically-active isomers of dideoxycarbocyclic nucleosides

Publications (1)

Publication Number	Publication Date
MY103801A true MY103801A (en)	1993-09-30

Family

ID=27264063

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MYPI89000064A MY103801A (en)	1988-01-20	1989-01-19	Dideoxydidehydrocarbocyclic nucleosides

Country Status (29)

Country	Link
JP (1)	JP2793825B2 (pt)
KR (1)	KR0127137B1 (pt)
AT (1)	AT397801B (pt)
AU (2)	AU626278B2 (pt)
BE (1)	BE1003815A4 (pt)
CA (1)	CA1339896C (pt)
CH (1)	CH679152A5 (pt)
DE (1)	DE3901502C2 (pt)
DK (1)	DK175131B1 (pt)
ES (1)	ES2010091A6 (pt)
FI (1)	FI93546C (pt)
FR (1)	FR2626002B1 (pt)
GB (1)	GB2217320B (pt)
GR (1)	GR890100033A (pt)
HU (1)	HU203755B (pt)
IE (1)	IE62275B1 (pt)
IL (1)	IL88999A (pt)
IT (1)	IT1229531B (pt)
LU (1)	LU87437A1 (pt)
MY (1)	MY103801A (pt)
NL (1)	NL8900122A (pt)
NO (1)	NO169123C (pt)
NZ (1)	NZ227663A (pt)
OA (1)	OA09031A (pt)
PL (1)	PL163814B1 (pt)
PT (1)	PT89482B (pt)
RU (1)	RU2114846C1 (pt)
SE (1)	SE505213C2 (pt)
YU (1)	YU47791B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1215339B (it) *	1987-01-14	1990-02-08	Co Pharma Corp Srl	Procedimento per la preparazione di 9-(idrossialchil)-ipoxantine
US5631370A (en)	1988-01-20	1997-05-20	Regents Of The University Of Minnesota	Optically-active isomers of dideoxycarbocyclic nucleosides
GB8815265D0 (en) *	1988-06-27	1988-08-03	Wellcome Found	Therapeutic nucleosides
US4939252A (en) *	1989-04-20	1990-07-03	Hoffmann-La Roche Inc.	Novel intermediates for the preparation of Carbovir
ES2136061T3 (es) *	1989-06-27	1999-11-16	Wellcome Found	Nucleosidos terapeuticos.
GB8916477D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
GB8916479D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
GB8916478D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
GB8916480D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
MY104575A (en) *	1989-12-22	1994-04-30	The Wellcome Foundation Ltd	Therapeutic nucleosides.
US5144034A (en) *	1990-04-06	1992-09-01	Glaxo Inc.	Process for the synthesis of cyclopentene derivatives of purines
US5241069A (en) *	1990-04-06	1993-08-31	Glaxo Inc.	Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives
US5126452A (en) *	1990-04-06	1992-06-30	Glaxo Inc.	Synthesis of purine substituted cyclopentene derivatives
US5057630A (en) *	1990-04-06	1991-10-15	Glaxo Inc.	Synthesis of cyclopentene derivatives
GB9108376D0 (en) *	1991-04-19	1991-06-05	Enzymatix Ltd	Cyclopentenes
KR960705825A (ko) *	1993-11-12	1996-11-08	게리 디. 스트리트	면역억제제로서 유용한 6-옥소-뉴클레오시드(6-Oxo-nucleosides useful as immunosuppressants)
GB9721780D0 (en)	1997-10-14	1997-12-10	Glaxo Group Ltd	Process for the synthesis of chloropurine intermediates
CN1115338C (zh) *	1998-10-30	2003-07-23	隆萨股份公司	4－[(2′,5′－二氨基－6′－卤代嘧啶－4′－基)氨基]－环戊－2－烯基甲醇的制备方法
KR100606625B1 (ko)	1998-10-30	2006-07-28	론자 아게	4-[(2',5'-디아미노-6'-할로피리미딘-4'-일)아미노]-시클로펜트-2-에닐메탄올의 제조 방법
TWI229674B (en)	1998-12-04	2005-03-21	Astra Pharma Prod	Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
GB9903091D0 (en) *	1999-02-12	1999-03-31	Glaxo Group Ltd	Therapeutic nucleoside compound
AR039540A1 (es)	2002-05-13	2005-02-23	Tibotec Pharm Ltd	Compuestos microbicidas con contenido de pirimidina o triazina
EP3831388B1 (en)	2018-07-27	2024-02-28	FUJIFILM Corporation	Cyclopentenyl purine derivative or salt thereof for use in suppressing adenovirus
WO2021191417A1 (en)	2020-03-27	2021-09-30	Som Innovation Biotech, S.A.	Compounds for use in the treatment of synucleinopathies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4268672A (en) *	1977-02-09	1981-05-19	The Regents Of The University Of Minnesota	Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
US4742064A (en) *	1985-09-10	1988-05-03	Regents Of The University Of Minnesota	Antiviral carbocyclic analogs of xylofuranosylpurines
JPS62177234A (ja) *	1986-01-30	1987-08-04	Mitsubishi Heavy Ind Ltd	遠心紡糸によるカ−ボン繊維の製造装置
IN164556B (pt) *	1986-03-06	1989-04-08	Takeda Chemical Industries Ltd
NZ229453A (en) *	1988-06-10	1991-08-27	Univ Minnesota & Southern Rese	A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) *	1988-06-27	1988-08-03	Wellcome Found	Therapeutic nucleosides
MY104575A (en) *	1989-12-22	1994-04-30	The Wellcome Foundation Ltd	Therapeutic nucleosides.

1989
- 1989-01-19 IE IE15389A patent/IE62275B1/en not_active IP Right Cessation
- 1989-01-19 KR KR1019890000551A patent/KR0127137B1/ko not_active IP Right Cessation
- 1989-01-19 NL NL8900122A patent/NL8900122A/nl not_active Application Discontinuation
- 1989-01-19 ES ES8900184A patent/ES2010091A6/es not_active Expired
- 1989-01-19 IT IT8947546A patent/IT1229531B/it active
- 1989-01-19 IL IL8899989A patent/IL88999A/en unknown
- 1989-01-19 JP JP1008744A patent/JP2793825B2/ja not_active Expired - Lifetime
- 1989-01-19 NZ NZ227663A patent/NZ227663A/xx unknown
- 1989-01-19 RU RU92004364A patent/RU2114846C1/ru active
- 1989-01-19 DE DE3901502A patent/DE3901502C2/de not_active Expired - Lifetime
- 1989-01-19 HU HU89210A patent/HU203755B/hu unknown
- 1989-01-19 FI FI890286A patent/FI93546C/fi not_active IP Right Cessation
- 1989-01-19 NO NO890253A patent/NO169123C/no not_active IP Right Cessation
- 1989-01-19 PT PT89482A patent/PT89482B/pt not_active IP Right Cessation
- 1989-01-19 OA OA59510A patent/OA09031A/xx unknown
- 1989-01-19 YU YU12389A patent/YU47791B/sh unknown
- 1989-01-19 DK DK198900234A patent/DK175131B1/da not_active IP Right Cessation
- 1989-01-19 PL PL89277261A patent/PL163814B1/pl unknown
- 1989-01-19 FR FR8900592A patent/FR2626002B1/fr not_active Expired - Lifetime
- 1989-01-19 SE SE8900192A patent/SE505213C2/sv not_active IP Right Cessation
- 1989-01-19 AT AT0010689A patent/AT397801B/de not_active IP Right Cessation
- 1989-01-19 LU LU87437A patent/LU87437A1/fr unknown
- 1989-01-19 BE BE8900061A patent/BE1003815A4/fr active
- 1989-01-19 CH CH172/89A patent/CH679152A5/de not_active IP Right Cessation
- 1989-01-19 MY MYPI89000064A patent/MY103801A/en unknown
- 1989-01-19 GB GB8901187A patent/GB2217320B/en not_active Expired - Lifetime
- 1989-01-19 GR GR890100033A patent/GR890100033A/el not_active IP Right Cessation
- 1989-01-19 CA CA000588614A patent/CA1339896C/en not_active Expired - Lifetime
- 1989-01-20 AU AU28671/89A patent/AU626278B2/en not_active Expired
1992
- 1992-01-13 AU AU10180/92A patent/AU637015B2/en not_active Expired

Also Published As

Publication number	Publication date
DE3901502A1 (de)	1989-07-27
GB2217320A (en)	1989-10-25
ES2010091A6 (es)	1989-10-16
SE8900192L (sv)	1989-07-21
FI890286A0 (fi)	1989-01-19
JPH02196788A (ja)	1990-08-03
PL163814B1 (en)	1994-05-31
NL8900122A (nl)	1989-08-16
NO890253L (no)	1989-07-21
SE505213C2 (sv)	1997-07-14
KR890011902A (ko)	1989-08-23
YU47791B (sr)	1996-01-09
JP2793825B2 (ja)	1998-09-03
PT89482A (pt)	1989-10-04
LU87437A1 (fr)	1989-08-30
OA09031A (en)	1991-03-31
YU12389A (en)	1991-10-31
NO169123C (no)	1992-05-13
AU637015B2 (en)	1993-05-13
PL277261A1 (en)	1989-09-18
PT89482B (pt)	1994-02-28
SE8900192D0 (sv)	1989-01-19
FI93546B (fi)	1995-01-13
HU203755B (en)	1991-09-30
IE62275B1 (en)	1995-01-25
AU2867189A (en)	1989-07-20
FI890286A (fi)	1989-07-21
DK23489A (da)	1989-07-21
AU1018092A (en)	1992-03-12
CA1339896C (en)	1998-06-02
GB2217320B (en)	1992-04-08
AU626278B2 (en)	1992-07-30
DK23489D0 (da)	1989-01-19
HUT48887A (en)	1989-07-28
FR2626002A1 (fr)	1989-07-21
NZ227663A (en)	1990-09-26
IT8947546A0 (it)	1989-01-19
AT397801B (de)	1994-07-25
IL88999A0 (en)	1989-08-15
IT1229531B (it)	1991-09-04
DE3901502C2 (de)	2002-06-13
CH679152A5 (pt)	1991-12-31
GB8901187D0 (en)	1989-03-15
NO169123B (no)	1992-02-03
IL88999A (en)	1994-12-29
DK175131B1 (da)	2004-06-14
KR0127137B1 (ko)	1997-12-29
FR2626002B1 (fr)	1994-01-28
ATA10689A (de)	1993-11-15
FI93546C (fi)	1995-04-25
GR890100033A (el)	1994-03-31
IE890153L (en)	1989-07-20
BE1003815A4 (fr)	1992-06-23
RU2114846C1 (ru)	1998-07-10
NO890253D0 (no)	1989-01-19

Publication	Publication Date	Title
MY103801A (en)	1993-09-30	Dideoxydidehydrocarbocyclic nucleosides
HK125893A (en)	1993-11-19	Morpholino-ethylester of mycophenolic acid and derivatives thereof,their preparation and use in pharmaceutical compositions
CA2009637A1 (en)	1990-08-08	Substituted-1,3-oxathiolanes with antiviral properties
MY102986A (en)	1993-03-31	Benzo (5,6) cycloheptapyridines, compositions and methods of use
IL99755A0 (en)	1992-08-18	Hydroxymethyl(methylenecyclopentyl)purines and pyrimidines and pharmaceutical compositions containing the same
DK0471236T3 (da)	1995-07-24	Imidazopyridinderivater og deres anvendelse
MY105523A (en)	1994-10-31	Substituted-1,3-oxathiolanes with antiviral properties.
DE68903226D1 (de)	1992-11-26	Dideoxydidehydrocarbocyclische nukleoside.
FI881816A0 (fi)	1988-04-19	Nya bicykliska foereningar, foerfarane foer deras framstaellning och dessa innehaollande farmaceutiska blandningar.
NZ222741A (en)	1990-10-26	Pharmaceutical compositions containing an interferon and a purine derivative
ES2046641T3 (es)	1994-02-01	Composicion antitumoral.
ES8800920A1 (es)	1987-12-01	Un procedimiento para preparar un derivado de 1,5-benzotiazepina
DK283984D0 (da)	1984-06-08	Benzodiazepinderivater og fremgangsmaade til fremstilling deraf
EP0272596A3 (en)	1990-03-28	Theophyllinemethyldithiolan and theophyllinemethyldithianyl derivates, a method for their preparation and pharmaceutical compositions in which they are included
OA06527A (fr)	1981-07-31	Préparation de derivés hydroxylés de l'isopropylamine pyrimidine (séquence base minéral).
GR3007498T3 (pt)	1993-07-30
DE3883434D1 (de)	1993-09-30	Mitomycinanaloge, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen.
ES2027507A6 (es)	1992-06-01	Procedimiento de preparacion de derivados selenofenicos.
NZ216741A (en)	1988-10-28	6-oxo-1,6-dihydropyridazines and pharmaceutical compositions
ES8605819A1 (es)	1986-04-01	Procedimiento de preparacion de nuevos derivados nucleosidos.
GR1000138B (el)	1991-09-27	Νεα παραγωγα ριβοφουρανουρονικου οξεος, μεθοδος δια την παρασευη αυτων και η χρησιμοποιησις αυτων.