ES8605819A1 - Procedimiento de preparacion de nuevos derivados nucleosidos. - Google Patents

Procedimiento de preparacion de nuevos derivados nucleosidos.

Info

Publication number
ES8605819A1
ES8605819A1 ES547820A ES547820A ES8605819A1 ES 8605819 A1 ES8605819 A1 ES 8605819A1 ES 547820 A ES547820 A ES 547820A ES 547820 A ES547820 A ES 547820A ES 8605819 A1 ES8605819 A1 ES 8605819A1
Authority
ES
Spain
Prior art keywords
optionally substituted
nucleoside derivatives
compounds
formula
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES547820A
Other languages
English (en)
Other versions
ES547820A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Magyar Tudomanyos Akademia Kozponti Kemiai Kutato Intezet
Original Assignee
Magyar Tudomanyos Akademia Kozponti Kemiai Kutato Intezet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Magyar Tudomanyos Akademia Kozponti Kemiai Kutato Intezet filed Critical Magyar Tudomanyos Akademia Kozponti Kemiai Kutato Intezet
Publication of ES547820A0 publication Critical patent/ES547820A0/es
Publication of ES8605819A1 publication Critical patent/ES8605819A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE NUEVOS DERIVADOS NUCLEOSIDOS. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), PARA OBTENER DERIVADOS NUCLEOSIDOS DE FORMULA (I) DONDE R Y R SON IGUALES O DIFERENTES Y REPRESENTAN H O UN ACILO OPTATIVAMENTE SUSTITUIDO, ALCANOILO DE CADENA RECTA O RAMIFICADA OPTATIVAMENTE SUSTITUIDO, AROILO OPTATIVAMENTE SUSTITUIDO O HETEROAROILO OPTATIVAMENTE SUSTITUIDO; DONDE OPTATIVAMENTE SE PUEDEN EFECTUAR UNA DE LAS REACCIONES: A) ACILACION DE UN COMPUESTO DE FORMULA (I) CON UN COMPUESTO DE FORMULAS Y-CL O (IV); B) DESACILACION DEL COMPUESTO DE FORMULA (I) CON AMONIACO; Y C) INTRODUCIR UN GRUPO BLOQUEADOR EN EL COMPUESTO DE FORMULA (I). TIENEN UTILIDAD POR INHIBIR LA MULTIPLICACION VIRAL.
ES547820A 1984-10-12 1985-10-11 Procedimiento de preparacion de nuevos derivados nucleosidos. Expired ES8605819A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU843821A HU192472B (en) 1984-10-12 1984-10-12 Process for preparing /e/-5-/2-bromo-vinyl/-uracyl derivatives

Publications (2)

Publication Number Publication Date
ES547820A0 ES547820A0 (es) 1986-04-01
ES8605819A1 true ES8605819A1 (es) 1986-04-01

Family

ID=10965655

Family Applications (1)

Application Number Title Priority Date Filing Date
ES547820A Expired ES8605819A1 (es) 1984-10-12 1985-10-11 Procedimiento de preparacion de nuevos derivados nucleosidos.

Country Status (18)

Country Link
JP (1) JPS61126097A (es)
KR (1) KR870001935B1 (es)
AT (1) ATA294685A (es)
BE (1) BE903381A (es)
DD (1) DD239595A5 (es)
DE (1) DE3536604A1 (es)
DK (1) DK465585A (es)
ES (1) ES8605819A1 (es)
FI (1) FI853969L (es)
FR (1) FR2571726A1 (es)
GB (1) GB2165539A (es)
HU (1) HU192472B (es)
IL (1) IL76661A0 (es)
IT (1) IT1186775B (es)
NL (1) NL8502794A (es)
NO (1) NO854041L (es)
PL (1) PL255741A1 (es)
SE (1) SE8504708L (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8912972D0 (en) * 1989-06-06 1989-07-26 Wellcome Found Therapeutic nucleosides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5136498A (ja) * 1974-09-20 1976-03-27 Tanabe Seiyaku Co 2*2**anhidoroarabinofuranoshirurashirujudotainoseiho
JPS5687599A (en) * 1979-12-19 1981-07-16 Yamasa Shoyu Co Ltd E 55 22halogenovinyl arabinofuranosyluracil and its preparation
NZ199764A (en) * 1981-03-20 1984-08-24 Beecham Group Plc 5-(2-halogenovinyl)-2'-deoxyuridine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
FR2571726A1 (fr) 1986-04-18
IL76661A0 (en) 1986-02-28
KR870001935B1 (ko) 1987-10-22
FI853969A0 (fi) 1985-10-11
IT8522442A0 (it) 1985-10-11
JPS61126097A (ja) 1986-06-13
DK465585D0 (da) 1985-10-11
IT1186775B (it) 1987-12-16
GB8525152D0 (en) 1985-11-13
DE3536604A1 (de) 1986-04-17
ATA294685A (de) 1987-03-15
NO854041L (no) 1986-04-14
SE8504708L (sv) 1986-04-13
PL255741A1 (en) 1986-08-12
HUT38655A (en) 1986-06-30
ES547820A0 (es) 1986-04-01
DK465585A (da) 1986-04-13
DD239595A5 (de) 1986-10-01
BE903381A (fr) 1986-04-07
NL8502794A (nl) 1986-05-01
SE8504708D0 (sv) 1985-10-11
GB2165539A (en) 1986-04-16
HU192472B (en) 1987-06-29
FI853969L (fi) 1986-04-13
KR860003270A (ko) 1986-05-21

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