MXPA02007289A - Agonistas y antagonistas novedosos de receptores de melanocortina. - Google Patents
Agonistas y antagonistas novedosos de receptores de melanocortina.Info
- Publication number
- MXPA02007289A MXPA02007289A MXPA02007289A MXPA02007289A MXPA02007289A MX PA02007289 A MXPA02007289 A MX PA02007289A MX PA02007289 A MXPA02007289 A MX PA02007289A MX PA02007289 A MXPA02007289 A MX PA02007289A MX PA02007289 A MXPA02007289 A MX PA02007289A
- Authority
- MX
- Mexico
- Prior art keywords
- antagonists
- receptor agonists
- melanocortin receptor
- novel melanocortin
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nutrition Science (AREA)
- Child & Adolescent Psychology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0002060A GB0002060D0 (en) | 2000-01-28 | 2000-01-28 | Novel aromatic amines |
GB0001948A GB0001948D0 (en) | 2000-01-28 | 2000-01-28 | Novel aromatic amines |
PCT/GB2001/000346 WO2001055106A2 (en) | 2000-01-28 | 2001-01-29 | Novel melanocortin receptor agonists and antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02007289A true MXPA02007289A (es) | 2003-09-22 |
Family
ID=26243502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02007289A MXPA02007289A (es) | 2000-01-28 | 2001-01-29 | Agonistas y antagonistas novedosos de receptores de melanocortina. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20030195212A1 (es) |
EP (1) | EP1254114A2 (es) |
JP (1) | JP2003520850A (es) |
KR (1) | KR20020075396A (es) |
AU (1) | AU2001228677A1 (es) |
BR (1) | BR0107893A (es) |
CA (1) | CA2398728A1 (es) |
IL (1) | IL150898A0 (es) |
MX (1) | MXPA02007289A (es) |
WO (1) | WO2001055106A2 (es) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002064091A2 (en) | 2001-02-13 | 2002-08-22 | Palatin Technologies, Inc. | Melanocortin metallopeptides for treatment of sexual dysfunction |
DZ3415A1 (fr) | 2000-08-31 | 2002-03-07 | Chiron Corp | Guanidinobenzamides comme mc4-r agonistes. |
DE60216747T2 (de) | 2001-04-09 | 2007-10-04 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Guanidinoverbindungen als melanocortin-4-rezeptor (mc4-r) agonisten |
US7732451B2 (en) | 2001-08-10 | 2010-06-08 | Palatin Technologies, Inc. | Naphthalene-containing melanocortin receptor-specific small molecule |
US7354923B2 (en) * | 2001-08-10 | 2008-04-08 | Palatin Technologies, Inc. | Piperazine melanocortin-specific compounds |
CA2462200A1 (en) | 2001-08-10 | 2003-02-20 | Palatin Technologies, Inc. | Peptidomimetics of biologically active metallopeptides |
US7655658B2 (en) | 2001-08-10 | 2010-02-02 | Palatin Technologies, Inc. | Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds |
US7718802B2 (en) | 2001-08-10 | 2010-05-18 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific piperazine compounds |
US7456184B2 (en) * | 2003-05-01 | 2008-11-25 | Palatin Technologies Inc. | Melanocortin receptor-specific compounds |
AU2002367427A1 (en) * | 2001-12-28 | 2003-07-24 | Takeda Chemical Industries, Ltd. | Biaryl compound and use thereof |
US7034033B2 (en) | 2002-05-23 | 2006-04-25 | Chiron Corporation | Substituted quinazolinone compounds |
AU2003280838A1 (en) * | 2002-11-19 | 2004-06-15 | Takeda Pharmaceutical Company Limited | Indole derivatives as somatostatin agonists or antagonists |
CN1729174B (zh) * | 2002-12-20 | 2015-10-21 | 西巴特殊化学品控股有限公司 | 胺的合成以及用于合成胺的中间体 |
GB0305681D0 (en) | 2003-03-12 | 2003-04-16 | Kudos Pharm Ltd | Phthalazinone derivatives |
US7727991B2 (en) | 2003-05-01 | 2010-06-01 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific single acyl piperazine compounds |
US7968548B2 (en) | 2003-05-01 | 2011-06-28 | Palatin Technologies, Inc. | Melanocortin receptor-specific piperazine compounds with diamine groups |
US7727990B2 (en) | 2003-05-01 | 2010-06-01 | Palatin Technologies, Inc. | Melanocortin receptor-specific piperazine and keto-piperazine compounds |
JP2007501861A (ja) | 2003-05-23 | 2007-02-01 | カイロン コーポレイション | Mc4−rアゴニストとしてのグアニジノ置換キナゾリノン化合物 |
KR20060105785A (ko) | 2003-11-19 | 2006-10-11 | 카이론 코포레이션 | 감소된 생체축적을 갖는 퀴나졸리논 화합물 |
US6974187B2 (en) * | 2004-01-28 | 2005-12-13 | Tachi-S Co., Ltd. | Vehicle seat structure |
DE602005026380D1 (de) | 2004-04-08 | 2011-03-31 | Astellas Pharma Inc | Verbindung ws727713 |
AU2005231034B2 (en) * | 2004-04-08 | 2010-04-08 | Telsar Pharma Inc. | Compound WS727713 |
US7709484B1 (en) | 2004-04-19 | 2010-05-04 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific piperazine compounds |
AU2005251745A1 (en) * | 2004-06-04 | 2005-12-22 | The Regents Of The University Of California | Compounds having activity in increasing ion transport by mutant-CFTR and uses thereof |
AU2007255366B2 (en) | 2006-06-09 | 2013-07-18 | Synact Pharma Aps | Phenyl pyrrole aminoguanidine derivatives |
US7834017B2 (en) | 2006-08-11 | 2010-11-16 | Palatin Technologies, Inc. | Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents |
GB0624987D0 (en) | 2006-12-14 | 2007-01-24 | Acure Pharma Ab | Novel aminoguanidines as melanocortin receptor ligands |
BRPI0808348A2 (pt) * | 2007-03-05 | 2014-07-15 | Hoffmann La Roche | Aminoamidas como antagonistas de orexina |
KR100878446B1 (ko) * | 2007-06-07 | 2009-01-13 | 일동제약주식회사 | 신규 펩티드 데포르밀라제 저해제 화합물 및 그 제조방법 |
WO2009051910A1 (en) * | 2007-10-16 | 2009-04-23 | The Regents Of The University Of California | Compounds having activity in increasing ion transport by mutant-cftr and uses thereof |
WO2012135615A2 (en) | 2011-03-30 | 2012-10-04 | Brown University | Enopeptins, uses thereof, and methods of synthesis thereto |
WO2012177896A1 (en) | 2011-06-24 | 2012-12-27 | Amgen Inc. | Trpm8 antagonists and their use in treatments |
PE20140868A1 (es) | 2011-06-24 | 2014-07-18 | Amgen Inc | Antagonistas trpm8 y su uso en tratamientos |
US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
CA2896437C (en) * | 2012-11-26 | 2021-01-19 | Takaaki Abe | Erythropoietin expression promoter |
US9834520B2 (en) | 2013-03-14 | 2017-12-05 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
EP3018126A4 (en) | 2013-07-03 | 2016-12-07 | Takeda Pharmaceuticals Co | HETEROCYCLIC COMPOUND |
EP3018123B1 (en) | 2013-07-03 | 2023-05-10 | Takeda Pharmaceutical Company Limited | Amide compound |
JP6372817B2 (ja) * | 2014-03-27 | 2018-08-15 | 国立大学法人東北大学 | 臓器線維化抑制剤 |
WO2016037072A2 (en) * | 2014-09-04 | 2016-03-10 | Brown University | Enopeptin analogas and methods of use thereof |
CN110770227B (zh) * | 2017-06-30 | 2024-03-01 | 拜耳动物保健有限责任公司 | 新的氮杂喹啉衍生物 |
EP3986554A4 (en) * | 2019-06-19 | 2023-07-19 | The Regents Of The University Of Michigan | TARGETING THE MELANOCORTIN 3 RECEPTOR FOR THE TREATMENT/PREVENTION OF EATING, METABOLISM AND/OR EMOTIONAL DISORDERS |
KR20240046551A (ko) * | 2021-08-10 | 2024-04-09 | 텍사스 하트 인스티튜트 | Lfa-1 및 vla-4의 피페라진 기반 작용제 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999055679A1 (en) * | 1998-04-28 | 1999-11-04 | Trega Biosciences, Inc. | Isoquinoline compound melanocortin receptor ligands and methods of using same |
-
2001
- 2001-01-29 BR BR0107893-3A patent/BR0107893A/pt not_active IP Right Cessation
- 2001-01-29 WO PCT/GB2001/000346 patent/WO2001055106A2/en not_active Application Discontinuation
- 2001-01-29 EP EP01946850A patent/EP1254114A2/en not_active Withdrawn
- 2001-01-29 MX MXPA02007289A patent/MXPA02007289A/es unknown
- 2001-01-29 CA CA002398728A patent/CA2398728A1/en not_active Abandoned
- 2001-01-29 US US10/182,192 patent/US20030195212A1/en not_active Abandoned
- 2001-01-29 JP JP2001555048A patent/JP2003520850A/ja not_active Withdrawn
- 2001-01-29 IL IL15089801A patent/IL150898A0/xx unknown
- 2001-01-29 KR KR1020027009602A patent/KR20020075396A/ko not_active Application Discontinuation
- 2001-01-29 AU AU2001228677A patent/AU2001228677A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BR0107893A (pt) | 2002-11-05 |
JP2003520850A (ja) | 2003-07-08 |
KR20020075396A (ko) | 2002-10-04 |
WO2001055106A3 (en) | 2002-03-21 |
IL150898A0 (en) | 2003-02-12 |
EP1254114A2 (en) | 2002-11-06 |
WO2001055106A2 (en) | 2001-08-02 |
CA2398728A1 (en) | 2001-08-02 |
AU2001228677A1 (en) | 2001-08-07 |
US20030195212A1 (en) | 2003-10-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MXPA02007289A (es) | Agonistas y antagonistas novedosos de receptores de melanocortina. | |
AU6497701A (en) | Melanocortin receptor agonists | |
AU4929601A (en) | Substituted piperidines as melanocortin receptor agonists | |
AU8828501A (en) | Substituted piperidines as melanocortin receptor agonists | |
MXPA03000738A (es) | Antagonistas de grelina. | |
ZA200300829B (en) | The use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands. | |
ZA200203450B (en) | beta2-adrenergic receptor agonists. | |
IL153308A0 (en) | Thrombin receptor antagonists | |
MXPA03004439A (es) | Aminotiazoles y su uso como antagonistas del receptor de adenosina. | |
PL366233A1 (en) | Substituted pyridoindoles as serotonin agonists and antagonists | |
EP1254116A4 (en) | ALPHA V INTEGRIN RECEPTOR ANTAGONISTS | |
MXPA03002691A (es) | Ligandos de receptor de melanocortina. | |
IL153181A0 (en) | Glucagon antagonists/inverse agonists | |
MXPA03005743A (es) | Antagonistas muscarinicos. | |
IL152700A0 (en) | Substituted 1-aminoalkyl-lactams and their use as muscarinc receptor antagonists | |
EP1252162A4 (en) | ALPHA V INTEGRIN RECEPTOR ANTAGONISTS | |
ZA200100978B (en) | Muscarinic agonists and antagonists. | |
AU2001290772A1 (en) | Alpha v integrin receptor antagonists | |
AU9259801A (en) | Alpha v integrin receptor antagonists | |
HK1042037A1 (en) | Vitronectin receptor antagonist. | |
MXPA03003892A (es) | Antagonistas del receptor bombesin. | |
HK1047750A1 (zh) | 趨化因子受體拮抗劑 | |
EP1351687A4 (en) | UROTENSIN II RECEPTOR ANTAGONISTS | |
AU9275001A (en) | Notch receptor agonists and uses | |
MXPA03004414A (es) | Natagonistas del receptor bombesin. |