EP1385879A4
(en)
*
|
2001-05-10 |
2005-02-02 |
Univ Queensland |
DIAGNOSIS AND THERAPY OF CANCER OF REPRODUCTIVE ORGANS
|
US7105526B2
(en)
|
2002-06-28 |
2006-09-12 |
Banyu Pharmaceuticals Co., Ltd. |
Benzimidazole derivatives
|
WO2004009124A2
(en)
*
|
2002-07-19 |
2004-01-29 |
Cytos Biotechnology Ag |
Ghrelin-carrier conjugates
|
ATE496940T1
(de)
|
2002-07-23 |
2011-02-15 |
Ipsen Pharma |
Ghrelin-analoga
|
TWI331922B
(en)
|
2002-08-09 |
2010-10-21 |
Ipsen Pharma Sas |
Growth hormone releasing peptides
|
US20040121407A1
(en)
*
|
2002-09-06 |
2004-06-24 |
Elixir Pharmaceuticals, Inc. |
Regulation of the growth hormone/IGF-1 axis
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
DK1648922T3
(da)
|
2003-07-31 |
2011-03-14 |
Tranzyme Pharma Inc |
Rumligt definerede makrocykliske forbindelser, der er anvendelige til opdagelse af lægemidler
|
US7550431B2
(en)
*
|
2003-07-31 |
2009-06-23 |
Tranzyme Pharma Inc. |
Spatially-defined macrocycles incorporating peptide bond surrogates
|
WO2005021026A2
(en)
*
|
2003-08-29 |
2005-03-10 |
Amylin Pharmaceuticals, Inc. |
Methods for treating or ameliorating ghrelin-associated diseases and disorders
|
WO2005028438A1
(ja)
|
2003-09-22 |
2005-03-31 |
Banyu Pharmaceutical Co., Ltd. |
新規ピペリジン誘導体
|
DE602004012207T2
(de)
*
|
2003-10-16 |
2009-03-12 |
F. Hoffmann-La Roche Ag |
Fluoreszent markierte Ghrelin-Peptide
|
EP2305352A1
(en)
|
2004-04-02 |
2011-04-06 |
Merck Sharp & Dohme Corp. |
5-alpha-reductase inhibitors for use in the treatment of men with metabolic and anthropometric disorders
|
US20090149512A1
(en)
*
|
2004-05-14 |
2009-06-11 |
Novo Nordisk A/S |
Use of Ghrelin Antagonists to the Treatment of Certain CNS Diseases
|
EP1814590B2
(en)
|
2004-11-01 |
2013-12-11 |
Amylin Pharmaceuticals, Inc. |
Treatment of obesity and related disorders
|
US7187208B2
(en)
*
|
2005-01-19 |
2007-03-06 |
Phaselink Semiconductor Corporation |
Complimentary metal oxide silicon low voltage positive emitter coupled logic buffer
|
US20090286723A1
(en)
|
2005-02-11 |
2009-11-19 |
Amylin Pharmaceuticals, Inc. |
Hybrid Polypeptides with Selectable Properties
|
US7737155B2
(en)
|
2005-05-17 |
2010-06-15 |
Schering Corporation |
Nitrogen-containing heterocyclic compounds and methods of use thereof
|
ES2574014T3
(es)
|
2005-05-30 |
2016-06-14 |
Msd K.K. |
Derivado de piperidina novedoso
|
US20090275648A1
(en)
*
|
2005-06-13 |
2009-11-05 |
Fraser Graeme L |
Macrocyclic ghrelin receptor antagonists and inverse agonists and methods of using the same
|
EP1916239A4
(en)
|
2005-08-10 |
2009-10-21 |
Banyu Pharma Co Ltd |
PYRIDONE COMPOUND
|
BRPI0614649A2
(pt)
|
2005-08-11 |
2011-04-12 |
Amylin Pharmaceuticals Inc |
polipeptìdeos hìbridos com propriedades selecionáveis
|
EP1921065B1
(en)
|
2005-08-24 |
2010-10-20 |
Banyu Pharmaceutical Co., Ltd. |
Phenylpyridone derivative
|
WO2007029847A1
(ja)
|
2005-09-07 |
2007-03-15 |
Banyu Pharmaceutical Co., Ltd. |
二環性芳香族置換ピリドン誘導体
|
CA2625920C
(en)
|
2005-09-28 |
2014-12-23 |
Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R |
Analogs of ghrelin
|
EP1940842B1
(en)
|
2005-09-29 |
2012-05-30 |
Merck Sharp & Dohme Corp. |
Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
|
CN101287464A
(zh)
|
2005-09-29 |
2008-10-15 |
科学研究和应用咨询股份公司 |
用于刺激胃肠运动性的组合物和方法
|
AU2006307046A1
(en)
|
2005-10-27 |
2007-05-03 |
Msd K.K. |
Novel benzoxathiin derivative
|
MY146564A
(en)
|
2005-11-10 |
2012-08-30 |
Msd Kk |
Aza-substituted spiro derivatives
|
US8992928B2
(en)
|
2006-02-11 |
2015-03-31 |
Victor Raso |
Isolated monoclonal antibody or antigen-binding fragment that cleaves octanoylated native ghrelin
|
US8088733B2
(en)
|
2006-07-06 |
2012-01-03 |
Tranzyme Pharma Inc. |
Methods of using macrocyclic agonists of the ghrelin receptor for treatment of gastrointestinal motility disorders
|
EP2698157B1
(en)
|
2006-09-22 |
2015-05-20 |
Merck Sharp & Dohme Corp. |
Method of treatment using fatty acid synthesis inhibitors
|
WO2008038692A1
(fr)
|
2006-09-28 |
2008-04-03 |
Banyu Pharmaceutical Co., Ltd. |
dÉrivÉ de diarylcÉtimine
|
AU2008233662B2
(en)
|
2007-04-02 |
2012-08-23 |
Msd K.K. |
Indoledione derivative
|
WO2009020419A1
(en)
*
|
2007-05-14 |
2009-02-12 |
Suzanne L Dickson |
New treatment for chemical substance addiction
|
US7879802B2
(en)
|
2007-06-04 |
2011-02-01 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
CA2714617A1
(en)
|
2008-03-06 |
2009-09-11 |
Banyu Pharmaceutical Co., Ltd. |
Alkylaminopyridine derivative
|
US20110015198A1
(en)
|
2008-03-28 |
2011-01-20 |
Banyu Pharmaceutical Co., Inc. |
Diarylmethylamide derivative having melanin-concentrating hormone receptor antagonism
|
EP3239170B1
(en)
|
2008-06-04 |
2019-03-20 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
EP2301936A1
(en)
|
2008-06-19 |
2011-03-30 |
Banyu Pharmaceutical Co., Ltd. |
Spirodiamine-diarylketoxime derivative
|
EP3241839B1
(en)
|
2008-07-16 |
2019-09-04 |
Bausch Health Ireland Limited |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
|
EP2319841A1
(en)
|
2008-07-30 |
2011-05-11 |
Msd K.K. |
(5-membered)-(5-membered) or (5-membered)-(6-membered) fused ring cycloalkylamine derivative
|
CA2741125A1
(en)
|
2008-10-22 |
2010-04-29 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
CA2741644C
(en)
|
2008-10-30 |
2013-05-07 |
Merck Sharp & Dohme Corp. |
Isonicotinamide orexin receptor antagonists
|
WO2010051206A1
(en)
|
2008-10-31 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
EP2379547A1
(en)
|
2008-12-16 |
2011-10-26 |
Schering Corporation |
Pyridopyrimidine derivatives and methods of use thereof
|
US20110243940A1
(en)
|
2008-12-16 |
2011-10-06 |
Schering Corporation |
Bicyclic pyranone derivatives and methods of use thereof
|
CN102812037A
(zh)
|
2009-10-30 |
2012-12-05 |
特兰齐姆制药公司 |
大环生长素释放肽受体拮抗剂和反向激动剂及其使用方法
|
US8895596B2
(en)
|
2010-02-25 |
2014-11-25 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
EP2677869B1
(en)
|
2011-02-25 |
2017-11-08 |
Merck Sharp & Dohme Corp. |
Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
|
AR088352A1
(es)
|
2011-10-19 |
2014-05-28 |
Merck Sharp & Dohme |
Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
|
US10039813B2
(en)
|
2012-02-07 |
2018-08-07 |
Massachusetts Institute Of Technology |
Use of antagonists of ghrelin or ghrelin receptor to prevent or treat stress-sensitive psychiatric illness
|
AU2013296470B2
(en)
|
2012-08-02 |
2016-03-17 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
AU2014219020A1
(en)
|
2013-02-22 |
2015-07-23 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
WO2014139388A1
(en)
|
2013-03-14 |
2014-09-18 |
Merck Sharp & Dohme Corp. |
Novel indole derivatives useful as anti-diabetic agents
|
CA2905435A1
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
WO2014144231A1
(en)
|
2013-03-15 |
2014-09-18 |
Massachusetts Institute Of Technology |
Use of antagonists of growth hormone or growth hormone receptor to prevent or treat stress-sensitive psychiatric illness
|
US9708367B2
(en)
|
2013-03-15 |
2017-07-18 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase and their uses
|
JP6606491B2
(ja)
|
2013-06-05 |
2019-11-13 |
シナジー ファーマシューティカルズ インコーポレイテッド |
グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
WO2015054500A2
(en)
|
2013-10-09 |
2015-04-16 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for downregulation of pro-inflammatory cytokines
|
US9119832B2
(en)
|
2014-02-05 |
2015-09-01 |
The Regents Of The University Of California |
Methods of treating mild brain injury
|
JP6769963B2
(ja)
|
2014-08-29 |
2020-10-14 |
ティエエッセ ファルマ ソチエタ レスポンサビリタ リミタータ |
α−アミノ−β−カルボキシムコン酸セミアルデヒド脱炭酸酵素の阻害剤
|
US10317418B2
(en)
|
2015-02-24 |
2019-06-11 |
Massachusetts Institute Of Technology |
Use of ghrelin or functional ghrelin receptor agonists to prevent and treat stress-sensitive psychiatric illness
|
AU2017342083A1
(en)
|
2016-10-14 |
2019-04-11 |
Tes Pharma S.R.L. |
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
|
EP3551176A4
(en)
|
2016-12-06 |
2020-06-24 |
Merck Sharp & Dohme Corp. |
ANTIDIABETIC HETEROCYCLIC COMPOUNDS
|
EP3558298A4
(en)
|
2016-12-20 |
2020-08-05 |
Merck Sharp & Dohme Corp. |
ANTIDIABETIC SPIROCHROMAN COMPOUNDS
|
KR20210111248A
(ko)
|
2018-11-20 |
2021-09-10 |
테스 파마 에스.알.엘. |
α-아미노-β-카르복시뮤콘산 세미알데하이드 데카르복실라제의 저해제
|
WO2020167706A1
(en)
|
2019-02-13 |
2020-08-20 |
Merck Sharp & Dohme Corp. |
5-alkyl pyrrolidine orexin receptor agonists
|
WO2021026047A1
(en)
|
2019-08-08 |
2021-02-11 |
Merck Sharp & Dohme Corp. |
Heteroaryl pyrrolidine and piperidine orexin receptor agonists
|
CR20230089A
(es)
|
2020-08-18 |
2023-04-11 |
Merck Sharp & Dohme Llc |
Agonistas de bicicloheptano pirrolidina de los receptores de orexina
|