MX360417B - Fenilpropanoides digliceridos para el tratamiento del cancer. - Google Patents
Fenilpropanoides digliceridos para el tratamiento del cancer.Info
- Publication number
- MX360417B MX360417B MX2012004160A MX2012004160A MX360417B MX 360417 B MX360417 B MX 360417B MX 2012004160 A MX2012004160 A MX 2012004160A MX 2012004160 A MX2012004160 A MX 2012004160A MX 360417 B MX360417 B MX 360417B
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- alkylcarbonyloxy
- alkoxy
- phenylpropanoid
- glycerol
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Abstract
La presente invención proporciona un método para el tratamiento de un cáncer en un sujeto, que involucra administrar al sujeto un compuesto de fórmula (II) o (II´) en donde R1, R2, R3, R4, R5, R6 y R7son independientemente H, OH, alcoxi o alquilcarboniloxi, o una sal farmacéuticamente aceptable del mismo. También se proporciona un compuesto de fórmula (II) o (II´), en donde R1 y R2 son independientemente OH, alcoxi o alquilcarboniloxi, R3 y R4 son independientemente H, OH, alcoxi o alquilcarboniloxi, R6 es H, alcoxi o alquilcarboniloxi, R5 es H, OH, o alquilcarboniloxi, R6 es H, o alcoxi, y R7 es H, o una sal farmacéuticamente aceptable del mismo. (ver fórmulas).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25028709P | 2009-10-09 | 2009-10-09 | |
| PCT/CA2010/001613 WO2011041907A1 (en) | 2009-10-09 | 2010-10-08 | Derivatives of di(phenylpropanoid) glycerol for the treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2012004160A MX2012004160A (es) | 2012-09-07 |
| MX360417B true MX360417B (es) | 2018-10-25 |
Family
ID=43352967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012004160A MX360417B (es) | 2009-10-09 | 2010-10-08 | Fenilpropanoides digliceridos para el tratamiento del cancer. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US9061993B2 (es) |
| EP (1) | EP2486026B1 (es) |
| JP (1) | JP5529280B2 (es) |
| CN (1) | CN102264713A (es) |
| BR (1) | BR112012008204A2 (es) |
| CA (1) | CA2715662C (es) |
| CY (1) | CY1123161T1 (es) |
| DK (1) | DK2486026T3 (es) |
| ES (1) | ES2810906T3 (es) |
| HR (1) | HRP20201217T1 (es) |
| HU (1) | HUE051549T2 (es) |
| LT (1) | LT2486026T (es) |
| MX (1) | MX360417B (es) |
| MY (2) | MY160378A (es) |
| PL (1) | PL2486026T3 (es) |
| PT (1) | PT2486026T (es) |
| RS (1) | RS60667B1 (es) |
| SI (1) | SI2486026T1 (es) |
| WO (1) | WO2011041907A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8907117B2 (en) * | 2011-09-08 | 2014-12-09 | Henry Lowe | Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues |
| US9402834B2 (en) | 2014-10-21 | 2016-08-02 | Ions Pharmaceutical S.À R.L. | Human therapeutic agents |
| US9907786B2 (en) | 2014-10-21 | 2018-03-06 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof |
| US10092550B2 (en) | 2014-10-21 | 2018-10-09 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3857873A (en) | 1974-02-11 | 1974-12-31 | Warner Lambert Co | 3-hydroxy-5-(3-(substituted-amino)-2-hydroxypropoxy)-benzyl alcohols |
| CH648753A5 (de) * | 1981-07-22 | 1985-04-15 | Givaudan & Cie Sa | Lichtschutzmittel. |
| CN1238333C (zh) * | 2003-06-18 | 2006-01-25 | 清华大学 | 药物化合物菠萝酰酯及其制备方法和用途 |
| US7713556B2 (en) | 2006-12-08 | 2010-05-11 | Henry Lowe | Anti-tumor and anti-inflammatory extracts of plant biomass and their uses |
| EP2104659B1 (en) * | 2007-01-08 | 2015-07-29 | AndroScience Corporation | Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and uses thereof |
| TWI383251B (zh) * | 2008-01-16 | 2013-01-21 | Eternal Chemical Co Ltd | 感光型聚醯亞胺 |
| KR101074149B1 (ko) * | 2009-04-15 | 2011-10-17 | 한밭대학교 산학협력단 | 신규 폴리페놀/폴리페놀 컨쥬게이트 화합물 및 그의 용도 |
| US8907117B2 (en) * | 2011-09-08 | 2014-12-09 | Henry Lowe | Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues |
-
2010
- 2010-10-08 CA CA2715662A patent/CA2715662C/en active Active
- 2010-10-08 SI SI201032026T patent/SI2486026T1/sl unknown
- 2010-10-08 DK DK10821532.8T patent/DK2486026T3/da active
- 2010-10-08 BR BR112012008204A patent/BR112012008204A2/pt not_active Application Discontinuation
- 2010-10-08 JP JP2012532432A patent/JP5529280B2/ja active Active
- 2010-10-08 MY MYPI2012001601A patent/MY160378A/en unknown
- 2010-10-08 EP EP10821532.8A patent/EP2486026B1/en active Active
- 2010-10-08 HU HUE10821532A patent/HUE051549T2/hu unknown
- 2010-10-08 CN CN201080003781XA patent/CN102264713A/zh active Pending
- 2010-10-08 US US12/901,113 patent/US9061993B2/en active Active
- 2010-10-08 PL PL10821532T patent/PL2486026T3/pl unknown
- 2010-10-08 RS RS20200931A patent/RS60667B1/sr unknown
- 2010-10-08 PT PT108215328T patent/PT2486026T/pt unknown
- 2010-10-08 ES ES10821532T patent/ES2810906T3/es active Active
- 2010-10-08 MY MYPI2016000361A patent/MY187188A/en unknown
- 2010-10-08 WO PCT/CA2010/001613 patent/WO2011041907A1/en active Application Filing
- 2010-10-08 LT LTEP10821532.8T patent/LT2486026T/lt unknown
- 2010-10-08 MX MX2012004160A patent/MX360417B/es active IP Right Grant
-
2015
- 2015-05-17 US US14/714,318 patent/US10052301B2/en active Active
-
2020
- 2020-08-03 HR HRP20201217TT patent/HRP20201217T1/hr unknown
- 2020-08-05 CY CY20201100724T patent/CY1123161T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT2486026T (pt) | 2020-08-21 |
| JP2013507327A (ja) | 2013-03-04 |
| US20110086912A1 (en) | 2011-04-14 |
| US20150246014A1 (en) | 2015-09-03 |
| CY1123161T1 (el) | 2021-10-29 |
| WO2011041907A1 (en) | 2011-04-14 |
| MX2012004160A (es) | 2012-09-07 |
| MY160378A (en) | 2017-03-15 |
| US10052301B2 (en) | 2018-08-21 |
| ES2810906T3 (es) | 2021-03-09 |
| PL2486026T3 (pl) | 2020-11-02 |
| HRP20201217T1 (hr) | 2020-12-11 |
| CN102264713A (zh) | 2011-11-30 |
| US9061993B2 (en) | 2015-06-23 |
| SI2486026T1 (sl) | 2020-10-30 |
| LT2486026T (lt) | 2020-09-10 |
| EP2486026A4 (en) | 2015-07-01 |
| RS60667B1 (sr) | 2020-09-30 |
| DK2486026T3 (da) | 2020-08-17 |
| EP2486026A1 (en) | 2012-08-15 |
| CA2715662C (en) | 2013-05-07 |
| BR112012008204A2 (pt) | 2017-07-18 |
| EP2486026B1 (en) | 2020-06-24 |
| MY187188A (en) | 2021-09-09 |
| JP5529280B2 (ja) | 2014-06-25 |
| HUE051549T2 (hu) | 2021-10-28 |
| CA2715662A1 (en) | 2010-12-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |