MX2016006025A - Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. - Google Patents
Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres.Info
- Publication number
- MX2016006025A MX2016006025A MX2016006025A MX2016006025A MX2016006025A MX 2016006025 A MX2016006025 A MX 2016006025A MX 2016006025 A MX2016006025 A MX 2016006025A MX 2016006025 A MX2016006025 A MX 2016006025A MX 2016006025 A MX2016006025 A MX 2016006025A
- Authority
- MX
- Mexico
- Prior art keywords
- cancers
- treatment
- active agents
- pharmaceutically active
- additional pharmaceutically
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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- A—HUMAN NECESSITIES
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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Abstract
La presente invención proporciona una terapia de combinación que incluye un inhibidor MDM2 y uno o más agentes farmacéuticamente activos adicionales, particularmente para el tratamiento de cánceres. La invención también se refiere a composiciones farmacéuticas que contiene un inhibidor MDM2 y uno o más agentes farmacéuticamente activos adicionales para el tratamiento de cánceres.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361902717P | 2013-11-11 | 2013-11-11 | |
PCT/US2014/065034 WO2015070224A2 (en) | 2013-11-11 | 2014-11-11 | Combination therapy including an mdm2 inhibitor and one or more additional pharmaceutically active agents for the treatment of cancers |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016006025A true MX2016006025A (es) | 2016-12-02 |
Family
ID=52001089
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020001550A MX2020001550A (es) | 2013-11-11 | 2014-11-11 | Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. |
MX2020013670A MX2020013670A (es) | 2013-11-11 | 2014-11-11 | Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. |
MX2016006025A MX2016006025A (es) | 2013-11-11 | 2014-11-11 | Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. |
MX2022008175A MX2022008175A (es) | 2013-11-11 | 2016-05-06 | Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. |
MX2022012320A MX2022012320A (es) | 2013-11-11 | 2016-05-06 | Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. |
MX2019009853A MX2019009853A (es) | 2013-11-11 | 2016-05-06 | Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020001550A MX2020001550A (es) | 2013-11-11 | 2014-11-11 | Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. |
MX2020013670A MX2020013670A (es) | 2013-11-11 | 2014-11-11 | Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022008175A MX2022008175A (es) | 2013-11-11 | 2016-05-06 | Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. |
MX2022012320A MX2022012320A (es) | 2013-11-11 | 2016-05-06 | Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. |
MX2019009853A MX2019009853A (es) | 2013-11-11 | 2016-05-06 | Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres. |
Country Status (30)
Country | Link |
---|---|
US (3) | US20160287569A1 (es) |
EP (2) | EP3068393B9 (es) |
JP (5) | JP2016535795A (es) |
KR (3) | KR102473485B1 (es) |
CN (2) | CN112933236A (es) |
AP (1) | AP2016009243A0 (es) |
AU (3) | AU2014346354A1 (es) |
BR (1) | BR112016010564A2 (es) |
CA (1) | CA2930244A1 (es) |
CL (1) | CL2016001131A1 (es) |
DK (1) | DK3068393T5 (es) |
EA (2) | EA202092456A3 (es) |
ES (1) | ES2916721T3 (es) |
HR (1) | HRP20220718T1 (es) |
HU (1) | HUE059351T2 (es) |
IL (2) | IL245568B (es) |
LT (1) | LT3068393T (es) |
MA (1) | MA39094B1 (es) |
MX (6) | MX2020001550A (es) |
MY (1) | MY192088A (es) |
NZ (2) | NZ758548A (es) |
PH (1) | PH12016500871A1 (es) |
PL (1) | PL3068393T3 (es) |
PT (1) | PT3068393T (es) |
RS (1) | RS63348B9 (es) |
SG (1) | SG10201902429PA (es) |
SI (1) | SI3068393T1 (es) |
TN (1) | TN2016000176A1 (es) |
UA (1) | UA120750C2 (es) |
WO (1) | WO2015070224A2 (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101623985B1 (ko) | 2007-03-28 | 2016-05-25 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 스티칭된 폴리펩티드 |
PT2603600T (pt) | 2010-08-13 | 2019-02-27 | Aileron Therapeutics Inc | Macrociclos peptidomiméticos |
CA2850166C (en) | 2011-09-27 | 2019-12-03 | Amgen Inc. | Heterocyclic compounds as mdm2 inhibitors for the treatment of cancer |
CN104039342A (zh) | 2011-10-18 | 2014-09-10 | 爱勒让治疗公司 | 拟肽大环化合物 |
BR112015009470A2 (pt) | 2012-11-01 | 2019-12-17 | Aileron Therapeutics Inc | aminoácidos dissubstituídos e seus métodos de preparação e uso |
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