MX2009011512A - Nuevos compuestos peptidos ciclicos. - Google Patents

Nuevos compuestos peptidos ciclicos.

Info

Publication number
MX2009011512A
MX2009011512A MX2009011512A MX2009011512A MX2009011512A MX 2009011512 A MX2009011512 A MX 2009011512A MX 2009011512 A MX2009011512 A MX 2009011512A MX 2009011512 A MX2009011512 A MX 2009011512A MX 2009011512 A MX2009011512 A MX 2009011512A
Authority
MX
Mexico
Prior art keywords
cyclic peptide
new cyclic
hepatitis
peptide compounds
virus
Prior art date
Application number
MX2009011512A
Other languages
English (en)
Inventor
Takuya Makino
Toshio Yamanaka
Hidenori Ohki
Junya Ishida
Ayako Toda
Yu Harayama
Shingeki Kunikawa
Hiroaki Mizuno
Hiroaki Ohtake
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2007902312A external-priority patent/AU2007902312A0/en
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of MX2009011512A publication Critical patent/MX2009011512A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

La presente invención se refiere a un nuevo compuesto péptido cíclico o una sal de él, que tiene actividades contra el virus de la hepatitis C basadas en la actividad inhibidora contra la replicación de ARN del replicón del virus de la hepatitis C, a un proceso para su preparación, a una composición farmacéutica que lo contiene, y a un método para el tratamiento profiláctico y/o terapéutico de la hepatitis C en un ser humano o en un animal.
MX2009011512A 2007-05-02 2008-04-25 Nuevos compuestos peptidos ciclicos. MX2009011512A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2007902312A AU2007902312A0 (en) 2007-05-02 New Cyclic Peptide Compounds
PCT/JP2008/058456 WO2008139986A1 (en) 2007-05-02 2008-04-25 New cyclic peptide compounds

Publications (1)

Publication Number Publication Date
MX2009011512A true MX2009011512A (es) 2009-11-12

Family

ID=39671779

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011512A MX2009011512A (es) 2007-05-02 2008-04-25 Nuevos compuestos peptidos ciclicos.

Country Status (14)

Country Link
US (1) US8603975B2 (es)
EP (2) EP2150269B1 (es)
JP (1) JP5459545B2 (es)
KR (1) KR20100017547A (es)
CN (1) CN101687012A (es)
AU (1) AU2008250254B2 (es)
BR (1) BRPI0810203A2 (es)
CA (1) CA2684557A1 (es)
ES (1) ES2396170T3 (es)
IL (1) IL201485A0 (es)
MX (1) MX2009011512A (es)
RU (1) RU2436795C2 (es)
TW (1) TW200911839A (es)
WO (1) WO2008139986A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102164947A (zh) * 2008-09-24 2011-08-24 安斯泰来制药有限公司 肽化合物及其制备方法
WO2010088573A1 (en) * 2009-01-30 2010-08-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis c infection
US8481483B2 (en) 2009-02-19 2013-07-09 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8349312B2 (en) 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
US8367053B2 (en) 2009-07-09 2013-02-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8685917B2 (en) 2009-07-09 2014-04-01 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
JP2015532277A (ja) 2012-09-29 2015-11-09 ノバルティス アーゲー 環状ペプチドおよび医薬としてのその使用
US8906853B2 (en) 2012-11-28 2014-12-09 Enanta Pharmaceuticals, Inc. [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection
KR20160045136A (ko) 2013-08-26 2016-04-26 이난타 파마슈티칼스, 인코포레이티드 C형 간염을 예방 또는 치료하기 위한 사이클로스포린 유사체
GB201414806D0 (en) 2014-08-20 2014-10-01 Ucl Business Plc Cyclosporin conjugates
US9669095B2 (en) 2014-11-03 2017-06-06 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis C infection
CN112661808B (zh) * 2020-12-23 2022-05-27 浙江大学 一种酯肽类化合物及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05271267A (ja) 1991-04-23 1993-10-19 Fujisawa Pharmaceut Co Ltd Ｆｒ９０１４５９物質、その製法及び用途
JP4350898B2 (ja) 1998-07-01 2009-10-21 デビオファーム・ソシエテ・アノニム 活性の特徴が改善された新規のシクロスポリン
CA2426381A1 (en) 2000-10-19 2002-04-25 Fujisawa Pharmaceutical Co., Ltd. Cell damage inhibitor
GB0320638D0 (en) * 2003-09-03 2003-10-01 Novartis Ag Organic compounds
JP2007015926A (ja) * 2003-10-06 2007-01-25 Fujisawa Pharmaceut Co Ltd Ｃ型肝炎治療剤
ES2357587T3 (es) 2004-10-01 2011-04-27 Debiopharm S.A. Uso de (d-meala)3-(etval)4-ciclosporina para el tratamiento de infección por hepatitis c.
RU2399628C2 (ru) 2004-10-01 2010-09-20 Скайнексис, Инк. Производные циклоспорина, замещенные 3-эфиром и 3-тиоэфиром, для лечения и профилактики инфекционного гепатита с
ES2314731T3 (es) * 2004-11-22 2009-03-16 Astellas Pharma Inc. Analogo de ciclosporina.
JP5218051B2 (ja) * 2005-10-26 2013-06-26 アステラス製薬株式会社 新規環状ペプチド化合物

Also Published As

Publication number Publication date
US20100120672A1 (en) 2010-05-13
JP2010526024A (ja) 2010-07-29
ES2396170T3 (es) 2013-02-19
IL201485A0 (en) 2010-05-31
CA2684557A1 (en) 2008-11-20
CN101687012A (zh) 2010-03-31
AU2008250254A1 (en) 2008-11-20
TW200911839A (en) 2009-03-16
RU2436795C2 (ru) 2011-12-20
EP2150269B1 (en) 2012-11-21
US8603975B2 (en) 2013-12-10
EP2455098A1 (en) 2012-05-23
WO2008139986A1 (en) 2008-11-20
BRPI0810203A2 (pt) 2014-10-14
JP5459545B2 (ja) 2014-04-02
EP2150269A1 (en) 2010-02-10
AU2008250254B2 (en) 2012-08-16
KR20100017547A (ko) 2010-02-16
RU2009144538A (ru) 2011-06-10

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Legal Events

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