MA29969B1 - Formulations de quinolinones - Google Patents

Formulations de quinolinones

Info

Publication number
MA29969B1
MA29969B1 MA30953A MA30953A MA29969B1 MA 29969 B1 MA29969 B1 MA 29969B1 MA 30953 A MA30953 A MA 30953A MA 30953 A MA30953 A MA 30953A MA 29969 B1 MA29969 B1 MA 29969B1
Authority
MA
Morocco
Prior art keywords
compound
quinolinones
formulations
tautomer
salt
Prior art date
Application number
MA30953A
Other languages
English (en)
Inventor
Joyce Chou
Augustus Okhamafe
Patricia Frech
Rampurma Gullapalli
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA29969B1 publication Critical patent/MA29969B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA PRÉSENTE INVENTION CONCERNE UNE FORMULATION PHARMACEUTIQUE COMPRENANT : UN COMPOSÉ DE FORMULE (I), UN TAUTOMÈRE DU COMPOSÉ, UN SEL DU COMPOSÉ, UN SEL DU TAUTOMÈRE OU UN MÉLANGE DE CEUX-CI ET AU MOINS UN INGRÉDIENT CHOISI DANS LE GROUPE COMPRENANT (I) LA CELLULOSE ; (II) LE DIOXYDE DE SILICIUM ; (III) LE STÉARATE DE MAGNÉSIUM ; ET (IV) UN INGRÉDIENT CHOISI PARMI LA CROSPOVIDONE, L'AMIDON ET LE LACTOSE.
MA30953A 2005-11-29 2008-05-20 Formulations de quinolinones MA29969B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74057705P 2005-11-29 2005-11-29
US74131705P 2005-12-01 2005-12-01

Publications (1)

Publication Number Publication Date
MA29969B1 true MA29969B1 (fr) 2008-11-03

Family

ID=38024178

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30953A MA29969B1 (fr) 2005-11-29 2008-05-20 Formulations de quinolinones

Country Status (23)

Country Link
US (2) US20080293738A1 (fr)
EP (2) EP2772257A1 (fr)
JP (1) JP2009517481A (fr)
KR (1) KR20080074143A (fr)
CN (1) CN102670530A (fr)
AR (1) AR062545A1 (fr)
AU (1) AU2006320591B2 (fr)
BR (1) BRPI0619370A2 (fr)
CA (1) CA2627544C (fr)
CL (1) CL2010000387A1 (fr)
EC (1) ECSP088467A (fr)
ES (1) ES2467162T3 (fr)
IL (1) IL190865A0 (fr)
MA (1) MA29969B1 (fr)
MY (1) MY148529A (fr)
NO (1) NO20082938L (fr)
NZ (1) NZ567550A (fr)
PE (1) PE20070760A1 (fr)
PL (1) PL1957074T3 (fr)
PT (1) PT1957074E (fr)
RU (1) RU2433826C2 (fr)
TW (1) TW200730176A (fr)
WO (1) WO2007064719A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20091628A1 (es) * 2008-03-19 2009-11-19 Novartis Ag Formas cristalinas y dos formas solvatadas de sales de acido lactico de 4-amino-5-fluoro-3-[5-(4-metilpiperazin-1-il)-1h-benzimidazol-2-il]quinolin-2(1h)-ona
KR20160129109A (ko) 2008-05-23 2016-11-08 아미라 파마슈티칼스 인코포레이티드 5-리폭시게나아제 활성화 단백질 억제제
ES2393949T3 (es) * 2008-07-03 2013-01-02 Novartis Ag Proceso de granulación en estado fundido
UY33472A (es) 2010-06-30 2012-01-31 Novartis Ag ?composiciones farmacéuticas que comprenden monohidrato de lactato de 4-amino-5-fluoro-3-[6-(4-metil-piperazin-1-il)-1hbencimidazol-2-il]-1h-quinolin-2-ona?.
WO2013063003A1 (fr) 2011-10-28 2013-05-02 Novartis Ag Méthode de traitement des tumeurs stromales gastro-intestinales
WO2013116293A1 (fr) 2012-01-31 2013-08-08 Novartis Ag Combinaison d'un inhibiteur de rtk avec un anti-œstrogène et son utilisation pour traiter le cancer
CN104427986A (zh) 2012-07-11 2015-03-18 诺华股份有限公司 治疗胃肠道基质瘤的方法
WO2014058785A1 (fr) 2012-10-10 2014-04-17 Novartis Ag Polythérapie
TWI535784B (zh) 2014-08-26 2016-06-01 財團法人工業技術研究院 剪切增稠配方、及包含其之複合材料
ES2959804T3 (es) 2018-12-06 2024-02-28 Glaxosmithkline Ip Dev Ltd Nueva formulación farmacéutica que comprende un modulador de STING

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JP3161780B2 (ja) 1991-09-30 2001-04-25 東レ・ダウコーニング・シリコーン株式会社 α，ω−ジヒドロキシフルオロアルキルメチルポリシロキサンの製造方法
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DE19610723A1 (de) 1996-03-19 1997-09-25 Bayer Ag Elektrolumineszierende Anordnungen unter Verwendung von Blendsystemen
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EP1086705A4 (fr) 1998-05-20 2002-02-06 Kyowa Hakko Kogyo Kk Inhibiteurs de l'activite du facteur de croissance endothelial vasculaire (vegf)
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Also Published As

Publication number Publication date
RU2008126384A (ru) 2010-01-10
WO2007064719A3 (fr) 2007-08-16
JP2009517481A (ja) 2009-04-30
PE20070760A1 (es) 2007-10-04
ECSP088467A (es) 2008-06-30
IL190865A0 (en) 2008-11-03
AU2006320591B2 (en) 2010-06-03
RU2433826C2 (ru) 2011-11-20
NO20082938L (no) 2008-06-30
EP1957074A2 (fr) 2008-08-20
KR20080074143A (ko) 2008-08-12
ES2467162T3 (es) 2014-06-12
WO2007064719A2 (fr) 2007-06-07
NZ567550A (en) 2011-08-26
AR062545A1 (es) 2008-11-19
MY148529A (en) 2013-04-30
CN102670530A (zh) 2012-09-19
BRPI0619370A2 (pt) 2011-09-27
US20120276200A1 (en) 2012-11-01
CA2627544C (fr) 2015-07-07
CA2627544A1 (fr) 2007-06-07
PL1957074T3 (pl) 2014-08-29
TW200730176A (en) 2007-08-16
EP1957074B1 (fr) 2014-03-19
CL2010000387A1 (es) 2010-08-06
PT1957074E (pt) 2014-06-25
US20080293738A1 (en) 2008-11-27
EP2772257A1 (fr) 2014-09-03
AU2006320591A1 (en) 2007-06-07

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