MA29759B1 - 1h-imidazopyridines a substituant hydroxy et procedes - Google Patents
1h-imidazopyridines a substituant hydroxy et procedesInfo
- Publication number
- MA29759B1 MA29759B1 MA30694A MA30694A MA29759B1 MA 29759 B1 MA29759 B1 MA 29759B1 MA 30694 A MA30694 A MA 30694A MA 30694 A MA30694 A MA 30694A MA 29759 B1 MA29759 B1 MA 29759B1
- Authority
- MA
- Morocco
- Prior art keywords
- substituted
- methods
- imidazopyridines
- compounds
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1H-imidazopyridines à substituant hydroxy et procédés Des 1H-imidazo[4,5-c]pyridine-4-amines à substituant hydroxy, avec un substituant hydroxy en position 2, des compositions pharmaceutiques contenant ces composés, des procédés pour la préparation des composés, des intermédiaires, et des méthodes d'utilisation de ces composés comme immunomodulateurs, pour induire la biosynthèse de cytokines chez des animaux et dans le traitement de maladies comprenant des maladies virales et maladies néoplasiques, sont décrits.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71370405P | 2005-09-02 | 2005-09-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA29759B1 true MA29759B1 (fr) | 2008-09-01 |
Family
ID=37561219
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA30694A MA29759B1 (fr) | 2005-09-02 | 2008-02-29 | 1h-imidazopyridines a substituant hydroxy et procedes |
Country Status (20)
Country | Link |
---|---|
US (2) | US20100152230A1 (fr) |
EP (1) | EP1924581A1 (fr) |
JP (1) | JP4584335B2 (fr) |
KR (1) | KR20080031496A (fr) |
CN (1) | CN101253173A (fr) |
AU (1) | AU2006287157A1 (fr) |
BR (1) | BRPI0615250A2 (fr) |
CA (1) | CA2620933A1 (fr) |
CR (1) | CR9781A (fr) |
EA (1) | EA200800396A1 (fr) |
EC (1) | ECSP088225A (fr) |
IL (1) | IL189262A0 (fr) |
MA (1) | MA29759B1 (fr) |
MX (1) | MX2008002414A (fr) |
NO (1) | NO20081393L (fr) |
RS (1) | RS20080128A (fr) |
SV (1) | SV2009002832A (fr) |
TN (1) | TNSN08099A1 (fr) |
WO (1) | WO2007028129A1 (fr) |
ZA (1) | ZA200801645B (fr) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040265351A1 (en) | 2003-04-10 | 2004-12-30 | Miller Richard L. | Methods and compositions for enhancing immune response |
BRPI0412902A (pt) | 2003-08-12 | 2006-09-26 | 3M Innovative Properties Co | compostos contendo imidazo substituìdo por oxima |
ES2406730T3 (es) | 2003-08-27 | 2013-06-07 | 3M Innovative Properties Company | Imidazoquinolinas sustituidas con ariloxi y arilalquilenoxi |
CA2537763A1 (fr) | 2003-09-05 | 2005-03-17 | 3M Innovative Properties Company | Traitement pour le lymphome a cellules b cd5<sp>+</sp> |
US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
RU2412942C2 (ru) | 2003-10-03 | 2011-02-27 | 3М Инновейтив Пропертиз Компани | Оксизамещенные имидазохинолины, способные модулировать биосинтез цитокинов |
JP2007508305A (ja) | 2003-10-03 | 2007-04-05 | スリーエム イノベイティブ プロパティズ カンパニー | ピラゾロピリジンおよびその類似物 |
AU2004291101A1 (en) | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Oxime substituted imidazo ring compounds |
EP1682544A4 (fr) | 2003-11-14 | 2009-05-06 | 3M Innovative Properties Co | Composes d'un anneau d'imidazo substitue par hydroxylamine |
MY161812A (en) | 2003-11-25 | 2017-05-15 | 3M Innovative Properties Co | Substituted imidazo ring systems and methods |
EP1701955A1 (fr) | 2003-12-29 | 2006-09-20 | 3M Innovative Properties Company | Imidazoquinolines a substitution arylalcenyle et arylalkynyle |
AU2004312508A1 (en) | 2003-12-30 | 2005-07-21 | 3M Innovative Properties Company | Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides |
AU2005228150A1 (en) | 2004-03-24 | 2005-10-13 | 3M Innovative Properties Company | Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines |
WO2005123080A2 (fr) | 2004-06-15 | 2005-12-29 | 3M Innovative Properties Company | Imidazoquinolines et imidazonaphthyridines substituees par un heterocyclyle contenant un azote |
WO2006065280A2 (fr) | 2004-06-18 | 2006-06-22 | 3M Innovative Properties Company | Composes a noyau imidazo a substitutif d'isoxazole, de dihydroisoxazole et d'oxadiazole |
US8541438B2 (en) | 2004-06-18 | 2013-09-24 | 3M Innovative Properties Company | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines |
US8026366B2 (en) | 2004-06-18 | 2011-09-27 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines |
JP5543068B2 (ja) | 2004-12-30 | 2014-07-09 | スリーエム イノベイティブ プロパティズ カンパニー | キラル縮合[1,2]イミダゾ[4,5−c]環状化合物 |
AU2005326708C1 (en) | 2004-12-30 | 2012-08-30 | 3M Innovative Properties Company | Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds |
US9248127B2 (en) | 2005-02-04 | 2016-02-02 | 3M Innovative Properties Company | Aqueous gel formulations containing immune response modifiers |
CA2602083A1 (fr) | 2005-02-09 | 2006-08-09 | Coley Pharmaceutical Group, Inc. | Composes cycliques du type thiazalo(4,5-c) substitues par un groupe du type oxime et hydroxylamine et methodes connexes |
AU2006212765B2 (en) | 2005-02-09 | 2012-02-02 | 3M Innovative Properties Company | Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines |
US7968563B2 (en) | 2005-02-11 | 2011-06-28 | 3M Innovative Properties Company | Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods |
CA2597446A1 (fr) | 2005-02-11 | 2006-08-31 | Coley Pharmaceutical Group, Inc. | Imidazoquinolines et imidazonaphthyridines substituees |
CA2598437A1 (fr) | 2005-02-23 | 2006-08-31 | Coley Pharmaceutical Group, Inc. | Methode d'induction preferentielle de la biosynthese d'interferon |
WO2006091567A2 (fr) | 2005-02-23 | 2006-08-31 | Coley Pharmaceutical Group, Inc. | Composes d'imidazoquinolines a substitution hydroxyalkyle et procedes |
CA2598695A1 (fr) | 2005-02-23 | 2006-09-21 | Coley Pharmaceutical Group, Inc. | Imidazoquinolines a substitution hydroxyalkyle |
EP1869043A2 (fr) | 2005-04-01 | 2007-12-26 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridine-1,4-diamines et analogues associes |
EP1863814A1 (fr) | 2005-04-01 | 2007-12-12 | Coley Pharmaceutical Group, Inc. | Composes cycliques 1-pyrazolo (3,4-c) substitues comme modulateurs de la biosynthese de cytokine destines au traitement d'infections virales et de maladies neoplastiques |
ZA200803029B (en) | 2005-09-09 | 2009-02-25 | Coley Pharm Group Inc | Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods |
AU2006287270A1 (en) | 2005-09-09 | 2007-03-15 | Coley Pharmaceutical Group, Inc. | Amide and carbamate derivatives of N-{2-[4-amino-2- (ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-1,1-dimethylethyl}methanesulfonamide and methods |
CA2628131C (fr) | 2005-11-04 | 2012-03-20 | Coley Pharmaceutical Group, Inc. | 1h-imidazoquinolines substituees par hydroxy et alcoxy et procedes correspondants |
WO2007093901A1 (fr) * | 2006-02-17 | 2007-08-23 | Pfizer Limited | Dérivés de 3-déazapurine en tant que modulateurs de tlr7 |
EP1988896A4 (fr) | 2006-02-22 | 2011-07-27 | 3M Innovative Properties Co | Conjugués du modificateur de réponse immune |
US8329721B2 (en) | 2006-03-15 | 2012-12-11 | 3M Innovative Properties Company | Hydroxy and alkoxy substituted 1H-imidazonaphthyridines and methods |
WO2008008432A2 (fr) | 2006-07-12 | 2008-01-17 | Coley Pharmaceutical Group, Inc. | Composés à cycle [1,2] imidazo [4,5-c] fusionné chiral substitué et procédés correspondants |
US8178539B2 (en) | 2006-09-06 | 2012-05-15 | 3M Innovative Properties Company | Substituted 3,4,6,7-tetrahydro-5H-1,2a,4a,8-tetraazacyclopenta[cd]phenalenes and methods |
US20080149123A1 (en) | 2006-12-22 | 2008-06-26 | Mckay William D | Particulate material dispensing hairbrush with combination bristles |
US20100120799A1 (en) | 2007-02-19 | 2010-05-13 | Smithkline Beecham Corporation | Purine derivatives as immunomodulators |
EP1997805A1 (fr) * | 2007-06-01 | 2008-12-03 | Commissariat à l'Energie Atomique | Compositions à activité antiparasite, applications associées au traitement des maladies infectieuses causées par des apicomplexans |
EP2188280B1 (fr) * | 2007-08-03 | 2011-03-09 | Pfizer Limited | Imidazopyridinones |
UA103195C2 (uk) | 2008-08-11 | 2013-09-25 | Глаксосмитклайн Ллк | Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань |
WO2010018130A1 (fr) | 2008-08-11 | 2010-02-18 | Smithkline Beecham Corporation | Dérivés de purine destinés à être utilisés pour le traitement de maladies allergiques, inflammatoires et infectieuses |
BRPI0917013A2 (pt) | 2008-08-11 | 2016-02-16 | Glaxosmithkline Llc | métodos para tratar doenças alérgicas e outras condições inflamatórias, e para tratar ou prevenir doença, composto, composição farmacêutica, e, uso de um composto |
US8802684B2 (en) | 2008-08-11 | 2014-08-12 | Glaxosmithkline Llc | Adenine derivatives |
CN102272134B (zh) | 2008-12-09 | 2013-10-16 | 吉里德科学公司 | Toll样受体调节剂 |
WO2011025938A2 (fr) | 2009-08-28 | 2011-03-03 | Array Biopharma Inc. | COMPOSÉS INHIBITEURS DE Raf ET LEURS PROCÉDÉS D'UTILISATION |
SI2491035T1 (sl) * | 2009-10-22 | 2017-10-30 | Gilead Sciences, Inc. | Derivati purina ali deazapurina uporabni za zdravljenje (med drugimi) virusnih okužb |
EP2534148A1 (fr) | 2010-02-10 | 2012-12-19 | GlaxoSmithKline LLC | Dérivés de purine et leurs utilisations pharmaceutiques |
US9242980B2 (en) | 2010-08-17 | 2016-01-26 | 3M Innovative Properties Company | Lipidated immune response modifier compound compositions, formulations, and methods |
MX347240B (es) | 2011-06-03 | 2017-04-20 | 3M Innovative Properties Co | Ligadores heterobifuncionales con segmentos polietilenglicol y conjugados modificadores de la respuesta inmunitaria elaborados a partir de los mismos. |
JP6415979B2 (ja) | 2011-06-03 | 2018-10-31 | スリーエム イノベイティブ プロパティズ カンパニー | ヒドラジノ1h−イミダゾキノリン−4−アミン及びこれから調製された複合体 |
PL2734186T3 (pl) | 2011-07-22 | 2019-01-31 | Glaxosmithkline Llc | Kompozycja |
CN103450198B (zh) * | 2012-05-29 | 2015-07-08 | 首都医科大学 | 咪唑并吡啶并咪唑-3-取代乙酸苄酯、其合成、抗肿瘤活性及应用 |
JP6196674B2 (ja) | 2012-08-24 | 2017-09-13 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーGlaxoSmithKline LLC | ピラゾロピリミジン化合物 |
CA2890201A1 (fr) | 2012-11-20 | 2014-05-30 | Glaxosmithkline Llc | Nouveaux composes |
AU2013348218B2 (en) | 2012-11-20 | 2016-10-13 | Glaxosmithkline Llc | Novel compounds |
CA2890198A1 (fr) | 2012-11-20 | 2014-05-30 | Diane Mary Coe | Nouveaux composes |
MX2017003284A (es) | 2014-09-16 | 2017-06-28 | Gilead Sciences Inc | Formas solidas de modulador de receptor tipo toll. |
US11306083B2 (en) | 2017-12-20 | 2022-04-19 | 3M Innovative Properties Company | Amide substituted imidazo[4,5-C]quinoline compounds with a branched chain linking group for use as an immune response modifier |
WO2019209811A1 (fr) | 2018-04-24 | 2019-10-31 | Bristol-Myers Squibb Company | Agonistes macrocycliques du récepteur 7 de type toll (tlr7) |
US11554120B2 (en) | 2018-08-03 | 2023-01-17 | Bristol-Myers Squibb Company | 1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor |
WO2021154664A1 (fr) | 2020-01-27 | 2021-08-05 | Bristol-Myers Squibb Company | Composés 1h-pyrazolo[4,3-d]pyrimidine utiles en tant qu'agonistes du récepteur de type toll 7 (tlr7) |
US20230144824A1 (en) | 2020-01-27 | 2023-05-11 | Bristol-Myers Squibb Company | 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS |
CN115210236A (zh) | 2020-01-27 | 2022-10-18 | 百时美施贵宝公司 | 作为Toll样受体7(TLR7)激动剂的1H-吡唑并[4,3-d]嘧啶化合物 |
EP4097103A1 (fr) | 2020-01-27 | 2022-12-07 | Bristol-Myers Squibb Company | Composés 1h-pyrazolo[4,3-d]pyrimidine utiles en tant qu'agonistes du récepteur de type toll 7 (tlr7) |
WO2021154663A1 (fr) | 2020-01-27 | 2021-08-05 | Bristol-Myers Squibb Company | Composés 1h-pyrazolo[4,3-d]pyrimidine utiles en tant qu'agonistes du récepteur de type toll 7 (tlr7) |
US20230127326A1 (en) | 2020-01-27 | 2023-04-27 | Bristol-Myers Squibb Company | C3-SUBSTITUTED 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS |
KR20220132601A (ko) | 2020-01-27 | 2022-09-30 | 브리스톨-마이어스 스큅 컴퍼니 | 톨-유사 수용체 7 (TLR7) 효능제로서의 1H-피라졸로[4,3-d]피리미딘 화합물 |
JP2023512206A (ja) | 2020-01-27 | 2023-03-24 | ブリストル-マイヤーズ スクイブ カンパニー | トール様受容体7(TLR7)アゴニストとしての1H-ピラゾロ[4,3-d]ピリミジン化合物 |
CN115135655B (zh) | 2020-01-27 | 2024-07-02 | 百时美施贵宝公司 | 作为Toll样受体7(TLR7)激动剂的1H-吡唑并[4,3-d]嘧啶化合物 |
CN117466808B (zh) * | 2023-12-27 | 2024-03-12 | 烟台新药创制山东省实验室 | 一种6-烷基-2,4-二羟基吡啶类衍生物的制备方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ288182B6 (en) * | 1993-07-15 | 2001-05-16 | Minnesota Mining & Mfg | Imidazo[4,5-c]pyridine-4-amines and pharmaceutical preparations based thereon |
NZ329798A (en) * | 1996-07-03 | 1999-04-29 | Japan Energy Corp | Purine derivatives their tautomers and salts thereof and interferon secretion inducers, antiviral agents and anticancer drugs containing the same |
JP4331944B2 (ja) * | 2001-04-17 | 2009-09-16 | 大日本住友製薬株式会社 | 新規アデニン誘導体 |
CZ301491B6 (cs) * | 2001-04-27 | 2010-03-24 | Eisai R&D Management Co., Ltd. | Pyrazolo[1,5-a]pyridiny a léciva s jejich obsahem |
NZ537054A (en) * | 2002-06-07 | 2006-10-27 | 3M Innovative Properties Co | Ether substituted imidazopyridines |
DE602004029145D1 (de) * | 2003-02-27 | 2010-10-28 | Palau Pharma Sa | Pyrazolopyridin-derivate |
US7517887B2 (en) * | 2003-04-09 | 2009-04-14 | General Atomics | Reversible inhibitors of S-adenosyl-L-homocysteine hydrolase and uses thereof |
JP2005089334A (ja) * | 2003-09-12 | 2005-04-07 | Sumitomo Pharmaceut Co Ltd | 8−ヒドロキシアデニン化合物 |
JP2007522093A (ja) * | 2003-09-22 | 2007-08-09 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 7−アミノアルキリデニル−複素環式キノロンおよびナフチリドン |
FR2860514A1 (fr) * | 2003-10-03 | 2005-04-08 | Sanofi Synthelabo | Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique |
AU2004291101A1 (en) * | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Oxime substituted imidazo ring compounds |
MY161812A (en) * | 2003-11-25 | 2017-05-15 | 3M Innovative Properties Co | Substituted imidazo ring systems and methods |
TW200616604A (en) * | 2004-08-26 | 2006-06-01 | Nicholas Piramal India Ltd | Nitric oxide releasing prodrugs containing bio-cleavable linker |
WO2007093901A1 (fr) * | 2006-02-17 | 2007-08-23 | Pfizer Limited | Dérivés de 3-déazapurine en tant que modulateurs de tlr7 |
-
2006
- 2006-09-01 WO PCT/US2006/034427 patent/WO2007028129A1/fr active Application Filing
- 2006-09-01 BR BRPI0615250-3A patent/BRPI0615250A2/pt not_active IP Right Cessation
- 2006-09-01 EA EA200800396A patent/EA200800396A1/ru unknown
- 2006-09-01 AU AU2006287157A patent/AU2006287157A1/en not_active Abandoned
- 2006-09-01 CN CNA2006800319190A patent/CN101253173A/zh active Pending
- 2006-09-01 CA CA002620933A patent/CA2620933A1/fr not_active Abandoned
- 2006-09-01 JP JP2008529359A patent/JP4584335B2/ja not_active Expired - Fee Related
- 2006-09-01 MX MX2008002414A patent/MX2008002414A/es unknown
- 2006-09-01 KR KR1020087005146A patent/KR20080031496A/ko not_active Application Discontinuation
- 2006-09-01 RS RSP-2008/0128A patent/RS20080128A/sr unknown
- 2006-09-01 EP EP06802901A patent/EP1924581A1/fr not_active Withdrawn
- 2006-09-01 US US12/065,490 patent/US20100152230A1/en not_active Abandoned
-
2008
- 2008-02-04 IL IL189262A patent/IL189262A0/en unknown
- 2008-02-19 ZA ZA200801645A patent/ZA200801645B/xx unknown
- 2008-02-26 EC EC2008008225A patent/ECSP088225A/es unknown
- 2008-02-29 TN TNP2008000099A patent/TNSN08099A1/fr unknown
- 2008-02-29 SV SV2008002832A patent/SV2009002832A/es not_active Application Discontinuation
- 2008-02-29 MA MA30694A patent/MA29759B1/fr unknown
- 2008-02-29 CR CR9781A patent/CR9781A/es not_active Application Discontinuation
- 2008-03-17 NO NO20081393A patent/NO20081393L/no not_active Application Discontinuation
-
2011
- 2011-10-20 US US13/277,619 patent/US20120035209A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2009507036A (ja) | 2009-02-19 |
IL189262A0 (en) | 2008-06-05 |
JP4584335B2 (ja) | 2010-11-17 |
ECSP088225A (es) | 2008-03-26 |
TNSN08099A1 (fr) | 2009-07-14 |
MX2008002414A (es) | 2008-03-27 |
AU2006287157A1 (en) | 2007-03-08 |
SV2009002832A (es) | 2009-02-19 |
WO2007028129A1 (fr) | 2007-03-08 |
EA200800396A1 (ru) | 2008-08-29 |
EP1924581A1 (fr) | 2008-05-28 |
RS20080128A (en) | 2009-05-06 |
CN101253173A (zh) | 2008-08-27 |
CR9781A (es) | 2008-03-26 |
US20100152230A1 (en) | 2010-06-17 |
BRPI0615250A2 (pt) | 2011-05-10 |
ZA200801645B (en) | 2010-08-25 |
US20120035209A1 (en) | 2012-02-09 |
KR20080031496A (ko) | 2008-04-08 |
CA2620933A1 (fr) | 2007-03-08 |
NO20081393L (no) | 2008-05-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA29759B1 (fr) | 1h-imidazopyridines a substituant hydroxy et procedes | |
MY161812A (en) | Substituted imidazo ring systems and methods | |
TW200639172A (en) | Pyrazolopyridines and analogs thereof | |
MA32070B1 (fr) | Dérivés hétérocycliques réunis par fusion et procédés d'utilisation associés | |
WO2005079195A3 (fr) | Pyrazolopyridines et analogues de celles-ci | |
MA47447A (fr) | 2-hétéroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides pour le traitement du cancer | |
BRPI0414856A (pt) | imidazoquinolinas alcóxi-substituìdas | |
MA35109B1 (fr) | Derives de nucleoside 2-substitues et procedes d'utilisation de ceux-ci pour le traitement de maladies virales | |
MY148480A (en) | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | |
WO2006091568A3 (fr) | Imidazonaphthyridines a substitution hydroxyalkyle | |
MA34308B1 (fr) | Triazolopyridines substituées | |
TW200505458A (en) | 1-amino 1h-imidazoquinolines | |
MA27347A1 (fr) | Inhibiteurs de protease du vih, compositions les contenant, leurs utilisations pharmaceutiques et matieres pour leur synthese | |
MA31764B1 (fr) | Composés et compositions en tant que modulateurs de l'activité de gpr119 | |
MA29932B1 (fr) | Inhibiteurs de la proteine d'activation de la 5-lipoxygenase (flap) | |
MA31881B1 (fr) | Dérivés de n-(arylamino)arylsulfonamide comprenant des polymorphes en tant qu'inhibiteurs de mek ainsi que compositions, procédés d'utilisation et procédés de préparation de ceux-ci | |
WO2007106854A3 (fr) | 1h-imidazonaphthyridines hydroxy et alcoxy substituées, et procédés associés | |
MA30352B1 (fr) | Pyridine [3,4-b] pyrazinones | |
WO2007056112A3 (fr) | 1h-imidazoquinolines substituees par hydroxy et alcoxy et procedes correspondants | |
MA31683B1 (fr) | Composes et procedes pour moduler fxr | |
TNSN07476A1 (fr) | Derives de n-(pyridine -2- yl) - sulfonamide | |
MA29931B1 (fr) | Inhibiteurs de la proteine d'activation de la 5-lipoxygenase (flap) | |
TNSN07066A1 (fr) | Inhibiteurs de l'arn-polymerase, dependant d'arn, du virus de l'hepatite c, et compositions et traitements les utilisant | |
MA30821B1 (fr) | Derives de pyrazoline utiles comme antagonistes des recepteurs de mineralocorticoïdes | |
MA30089B1 (fr) | (arylsulfonyl)-pyrasolopiperidines |