DE602004029145D1 - Pyrazolopyridin-derivate - Google Patents
Pyrazolopyridin-derivateInfo
- Publication number
- DE602004029145D1 DE602004029145D1 DE602004029145T DE602004029145T DE602004029145D1 DE 602004029145 D1 DE602004029145 D1 DE 602004029145D1 DE 602004029145 T DE602004029145 T DE 602004029145T DE 602004029145 T DE602004029145 T DE 602004029145T DE 602004029145 D1 DE602004029145 D1 DE 602004029145D1
- Authority
- DE
- Germany
- Prior art keywords
- pyrazolopyridine derivatives
- pyrazolopyridine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000005229 pyrazolopyridines Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200300640A ES2214150B1 (es) | 2003-02-27 | 2003-02-27 | "nuevos derivados de pirazolopiridinas". |
ES200300727A ES2214976B1 (es) | 2003-03-14 | 2003-03-14 | "nuevos derivados de pirazolopiridinas". |
ES200302504 | 2003-10-27 | ||
PCT/EP2004/001974 WO2004076450A1 (en) | 2003-02-27 | 2004-02-27 | Pyrazolopyridine derivates |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004029145D1 true DE602004029145D1 (de) | 2010-10-28 |
Family
ID=32930978
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004029145T Expired - Lifetime DE602004029145D1 (de) | 2003-02-27 | 2004-02-27 | Pyrazolopyridin-derivate |
Country Status (30)
Country | Link |
---|---|
US (3) | US7468376B2 (de) |
EP (1) | EP1611131B1 (de) |
JP (1) | JP4814783B2 (de) |
KR (1) | KR101312736B1 (de) |
AR (1) | AR043416A1 (de) |
AT (1) | ATE481402T1 (de) |
AU (1) | AU2004215644B2 (de) |
BR (1) | BRPI0407811A (de) |
CA (1) | CA2515197C (de) |
CL (1) | CL2004000398A1 (de) |
CY (1) | CY1111544T1 (de) |
DE (1) | DE602004029145D1 (de) |
DK (1) | DK1611131T3 (de) |
EC (2) | ECSP056041A (de) |
HK (1) | HK1085214A1 (de) |
HR (1) | HRP20050682B1 (de) |
IL (1) | IL196021A (de) |
IS (1) | IS2875B (de) |
MX (1) | MXPA05009069A (de) |
NO (1) | NO331917B1 (de) |
NZ (1) | NZ541836A (de) |
PE (1) | PE20050521A1 (de) |
PL (1) | PL378296A1 (de) |
PT (1) | PT1611131E (de) |
RS (1) | RS51768B (de) |
RU (1) | RU2359971C2 (de) |
SI (1) | SI1611131T1 (de) |
TW (1) | TWI325865B (de) |
UA (1) | UA81453C2 (de) |
WO (1) | WO2004076450A1 (de) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS51768B (sr) * | 2003-02-27 | 2011-12-31 | Palau Pharma S.A. | Derivati pirazolpiridina |
ES2241496B1 (es) * | 2004-04-15 | 2006-12-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de piridina. |
TW200618800A (en) * | 2004-08-03 | 2006-06-16 | Uriach Y Compania S A J | Heterocyclic compounds |
GB0427604D0 (en) * | 2004-12-16 | 2005-01-19 | Novartis Ag | Organic compounds |
FR2880891B1 (fr) * | 2005-01-19 | 2007-02-23 | Aventis Pharma Sa | Pyrazolo pyridines substituees, compositions les contenant, procede de fabrication et utilisation |
PE20061119A1 (es) | 2005-01-19 | 2006-11-27 | Aventis Pharma Sa | PIRAZOLO PIRIDINAS SUSTITUIDAS COMO INHIBIDORES DE CINASAS FAK, KDR Y Tie |
PT1899333E (pt) * | 2005-06-27 | 2009-04-23 | Sanofi Aventis | Derivados pirazolopiridina como inibidores da cinase do receptor beta-adrenérgico 1 |
AU2006264170A1 (en) * | 2005-06-27 | 2007-01-04 | Ambrilia Biopharma Inc. | Pyrazolo[3,4-b]pyridin-2-yl)-benzoic acid derivatives as HIV integrase inhibitors |
ES2270715B1 (es) | 2005-07-29 | 2008-04-01 | Laboratorios Almirall S.A. | Nuevos derivados de pirazina. |
FR2889526B1 (fr) | 2005-08-04 | 2012-02-17 | Aventis Pharma Sa | 7-aza-indazoles substitues, compositions les contenant, procede de fabrication et utilisation |
EP1926734A1 (de) | 2005-08-22 | 2008-06-04 | Amgen Inc. | Als modulatoren von kinaseenzymen geeignete pyrazolopyridin- und pyrazolopyrimidinverbindungen |
MX2008002385A (es) * | 2005-08-25 | 2008-03-18 | Hoffmann La Roche | Inhibidores de proteinas cinasas activads por mitogenos p38 y metodos para utilizarlos. |
AU2006283935A1 (en) * | 2005-08-25 | 2007-03-01 | F. Hoffmann-La Roche Ag | Fused pyrazole as p38 MAP kinase inhibitors |
US20100152230A1 (en) * | 2005-09-02 | 2010-06-17 | Pfizer Inc. | Hydroxy substituted 1h-imidazopyridines and methods |
ES2274712B1 (es) | 2005-10-06 | 2008-03-01 | Laboratorios Almirall S.A. | Nuevos derivados imidazopiridina. |
CA2628179A1 (en) | 2005-11-15 | 2007-05-24 | Vertex Pharmaceuticals Incorporated | Azaindazoles useful as inhibitors of kinases |
EP1932845A1 (de) * | 2006-12-15 | 2008-06-18 | Bayer Schering Pharma Aktiengesellschaft | 3-H-Pyrazolopyridine und Salze davon, diese enthaltende pharmazeutische Zusammensetzungen , Verfahren zur ihrer Herstellung und ihre Verwendung |
AR064348A1 (es) * | 2006-12-15 | 2009-04-01 | Bayer Schering Pharma Ag | 3-h-pirazolopiridinas y sales de estas, composiciones farmaceuticas que las comprenden, metodos para prepararlas y sus usos |
WO2008104473A2 (en) * | 2007-02-28 | 2008-09-04 | F. Hoffmann-La Roche Ag | Pyrazolopyriidine derivatives and their use as kinase inhibitors |
EP1992344A1 (de) | 2007-05-18 | 2008-11-19 | Institut Curie | P38 Alpha als therapeutisches Target für Erkrankungen, die mit einer FGFR3- Mutation assoziiert sind |
WO2009055033A1 (en) * | 2007-10-26 | 2009-04-30 | Amgen Inc. | Pyrazolo-pyridinone derivatives and methods of use |
EP2070929A1 (de) | 2007-12-11 | 2009-06-17 | Bayer Schering Pharma Aktiengesellschaft | Alkynylarylverbindungen und Salze davon, pharmazeutische Zusammensetzungen damit sowie Verfahren zu ihrer Herstellung und Verwendung |
WO2009095752A1 (en) * | 2008-01-29 | 2009-08-06 | Glenmark Pharmaceuticals, S.A. | Fused pyrazole derivatives as cannabinoid receptor modulators |
WO2010093595A1 (en) | 2009-02-10 | 2010-08-19 | E. I. Du Pont De Nemours And Company | Fungicidal 2-pyridones |
WO2010111527A1 (en) * | 2009-03-26 | 2010-09-30 | Plexxikon, Inc. | Pyrazolo [ 3, 4 -b] pyridines as kinase inhibitors and their medical use |
EP2464231A4 (de) * | 2009-08-10 | 2013-02-06 | Samumed Llc | Indazole als wnt/b-catenin-signalisierungspfadhemmer und therapeutische anwendungen davon |
BR112012002854B1 (pt) | 2009-08-10 | 2020-02-18 | Samumed, Llc | Composto ou sal farmaceuticamente aceitável, composição farmacêutica e uso dos mesmos |
EP2789615B1 (de) | 2009-08-11 | 2017-05-03 | Bristol-Myers Squibb Company | Azaindazole als BTK-Kinasemodulatoren und Verwendung davon |
FR2951172B1 (fr) * | 2009-10-13 | 2014-09-26 | Pf Medicament | Derives pyrazolopyridines en tant qu'agent anticancereux |
PL3001903T3 (pl) | 2009-12-21 | 2018-03-30 | Samumed, Llc | 1H-pirazolo[3,4-b]pirydyny i ich zastosowania terapeutyczne |
JP2013534539A (ja) | 2010-07-15 | 2013-09-05 | ブリストル−マイヤーズ スクイブ カンパニー | アザインダゾール化合物 |
CN102617548A (zh) * | 2011-01-31 | 2012-08-01 | 北京赛林泰医药技术有限公司 | 作为gpr受体激动剂的双环杂芳基化合物及其组合物和应用 |
EP2678316A2 (de) | 2011-02-24 | 2014-01-01 | Cephalon, Inc. | Substituierte aromatische schwefelverbindungen und verfahren zu ihrer verwendung |
CN103929963A (zh) | 2011-09-14 | 2014-07-16 | 萨穆梅德有限公司 | 吲唑-3-羧酰胺及其作为WNT/β-CATENIN信号传导通路抑制剂的用途 |
PH12017500997A1 (en) | 2012-04-04 | 2018-02-19 | Samumed Llc | Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof |
MA37577B1 (fr) | 2012-05-04 | 2018-05-31 | Samumed Llc | 1h-pyrazolo[3,4-b]pyridines et leurs utilisations thérapeutiques |
RU2495039C1 (ru) * | 2012-07-31 | 2013-10-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Пермский государственный национальный исследовательский университет" | МЕТИЛ 3-МЕТИЛ-5-[2-(4-АРИЛАМИНО)-2-ОКСОАЦЕТИЛ]-1,6-ДИФЕНИЛ-1Н-ПИРАЗОЛО[3,4-b]ПИРИДИН-4-КАРБОКСИЛАТЫ И МЕТИЛ 3-МЕТИЛ-5-[2-(4-АРИЛАМИНО)-2-ОКСОАЦЕТИЛ]-6-СТИРИЛ-1-ФЕНИЛ-1Н-ПИРАЗОЛО[3,4-b]ПИРИДИН-4-КАРБОКСИЛАТЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ |
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CN104230922B (zh) * | 2013-06-19 | 2016-12-28 | 中国科学院上海药物研究所 | 一类五元杂环并吡啶类化合物及其制备方法和用途 |
EP3409674B1 (de) | 2013-10-17 | 2022-04-06 | Blueprint Medicines Corporation | Verfahrung zur herstellung von zusammensetzungen zur behandlung von erkrankungen im zusammenhang mit kit |
WO2016040182A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof |
WO2016040181A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040180A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040185A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof |
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-
2004
- 2004-02-27 RS YU20050609A patent/RS51768B/sr unknown
- 2004-02-27 UA UAA200507292A patent/UA81453C2/xx unknown
- 2004-02-27 NZ NZ541836A patent/NZ541836A/en not_active IP Right Cessation
- 2004-02-27 RU RU2005130020/04A patent/RU2359971C2/ru active IP Right Revival
- 2004-02-27 PE PE2004000211A patent/PE20050521A1/es not_active Application Discontinuation
- 2004-02-27 PL PL378296A patent/PL378296A1/pl unknown
- 2004-02-27 US US10/547,232 patent/US7468376B2/en not_active Expired - Fee Related
- 2004-02-27 MX MXPA05009069A patent/MXPA05009069A/es active IP Right Grant
- 2004-02-27 JP JP2006501971A patent/JP4814783B2/ja not_active Expired - Fee Related
- 2004-02-27 WO PCT/EP2004/001974 patent/WO2004076450A1/en active Application Filing
- 2004-02-27 DE DE602004029145T patent/DE602004029145D1/de not_active Expired - Lifetime
- 2004-02-27 AT AT04715268T patent/ATE481402T1/de active
- 2004-02-27 EP EP04715268A patent/EP1611131B1/de not_active Expired - Lifetime
- 2004-02-27 PT PT04715268T patent/PT1611131E/pt unknown
- 2004-02-27 SI SI200431568T patent/SI1611131T1/sl unknown
- 2004-02-27 AU AU2004215644A patent/AU2004215644B2/en not_active Ceased
- 2004-02-27 CL CL200400398A patent/CL2004000398A1/es unknown
- 2004-02-27 CA CA2515197A patent/CA2515197C/en not_active Expired - Fee Related
- 2004-02-27 KR KR1020057016025A patent/KR101312736B1/ko not_active IP Right Cessation
- 2004-02-27 BR BRPI0407811-0A patent/BRPI0407811A/pt not_active IP Right Cessation
- 2004-02-27 DK DK04715268.1T patent/DK1611131T3/da active
- 2004-02-27 AR ARP040100616A patent/AR043416A1/es not_active Application Discontinuation
- 2004-02-27 TW TW093105205A patent/TWI325865B/zh not_active IP Right Cessation
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2005
- 2005-07-14 IS IS7939A patent/IS2875B/is unknown
- 2005-07-27 NO NO20053647A patent/NO331917B1/no not_active IP Right Cessation
- 2005-07-29 HR HRP20050682AA patent/HRP20050682B1/hr not_active IP Right Cessation
- 2005-09-27 EC EC2005006041A patent/ECSP056041A/es unknown
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2006
- 2006-06-24 HK HK06107182.7A patent/HK1085214A1/xx not_active IP Right Cessation
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2008
- 2008-09-08 US US12/206,289 patent/US8536194B2/en active Active
- 2008-12-18 IL IL196021A patent/IL196021A/en active IP Right Grant
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2009
- 2009-07-29 US US12/511,469 patent/US20090286983A1/en not_active Abandoned
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2010
- 2010-12-10 CY CY20101101149T patent/CY1111544T1/el unknown
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2012
- 2012-03-30 EC ECSP12006041 patent/ECSP12006041A/es unknown
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