LU83032A1 - 3-acylamino-5(pyridinyl)-2(1h)-pyridinones,leur preparation et leur utilisation comme agents cardiotoniques - Google Patents

3-acylamino-5(pyridinyl)-2(1h)-pyridinones,leur preparation et leur utilisation comme agents cardiotoniques Download PDF

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Publication number
LU83032A1
LU83032A1 LU83032A LU83032A LU83032A1 LU 83032 A1 LU83032 A1 LU 83032A1 LU 83032 A LU83032 A LU 83032A LU 83032 A LU83032 A LU 83032A LU 83032 A1 LU83032 A1 LU 83032A1
Authority
LU
Luxembourg
Prior art keywords
pyridinyl
pyridinone
acid
cardiotonic
compound
Prior art date
Application number
LU83032A
Other languages
English (en)
French (fr)
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of LU83032A1 publication Critical patent/LU83032A1/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
LU83032A 1979-12-26 1980-12-23 3-acylamino-5(pyridinyl)-2(1h)-pyridinones,leur preparation et leur utilisation comme agents cardiotoniques LU83032A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/106,764 US4271168A (en) 1979-12-26 1979-12-26 Selected 3-acylamino-5-[4(or 3)-pyridinyl]-2(1H)-pyridinones
US10676479 1979-12-26

Publications (1)

Publication Number Publication Date
LU83032A1 true LU83032A1 (fr) 1981-07-23

Family

ID=22313122

Family Applications (1)

Application Number Title Priority Date Filing Date
LU83032A LU83032A1 (fr) 1979-12-26 1980-12-23 3-acylamino-5(pyridinyl)-2(1h)-pyridinones,leur preparation et leur utilisation comme agents cardiotoniques

Country Status (25)

Country Link
US (1) US4271168A (no)
JP (1) JPS56103164A (no)
KR (1) KR830004291A (no)
AR (1) AR230435A1 (no)
AT (1) AT373876B (no)
AU (1) AU6556680A (no)
BE (1) BE886766A (no)
CA (1) CA1131231A (no)
DE (1) DE3048635A1 (no)
DK (1) DK550480A (no)
ES (1) ES8201136A1 (no)
FI (1) FI803973L (no)
FR (1) FR2472563A1 (no)
GB (1) GB2066251B (no)
IE (1) IE50523B1 (no)
IL (1) IL61690A (no)
IT (1) IT1134860B (no)
LU (1) LU83032A1 (no)
NL (1) NL8006824A (no)
NO (1) NO803911L (no)
NZ (1) NZ195878A (no)
PH (1) PH15974A (no)
PT (1) PT72264B (no)
SE (1) SE8009134L (no)
ZA (1) ZA807864B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS587411A (ja) * 1981-07-07 1983-01-17 Mitsui Toatsu Chem Inc 薄肉射出成形用プロピレン/エチレン共重合体の製造方法
US4432979A (en) * 1981-10-26 1984-02-21 William H. Rorer, Inc. Pyridone compounds
BE896678A (fr) * 1982-05-18 1983-11-07 Sandoz Sa Nouveaux derives de la 2 (1h)-pyridinone, leur preparation et leur utilisation comme medicaments.
IT8367883A0 (it) * 1982-08-23 1983-08-22 Rorer Int Overseas Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche
US4666913A (en) * 1985-11-22 1987-05-19 William H. Rorer, Inc. Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses
KR20070095952A (ko) * 2004-12-16 2007-10-01 버텍스 파마슈티칼스 인코포레이티드 염증성 질환, 증식성 질환 및 면역학적으로 매개된 질환치료용 Tec 계열 단백질 키나제의 억제제로서 유용한피리드-2-온

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4072746A (en) * 1975-10-14 1978-02-07 Sterling Drug Inc. 3-Amino-5-(pyridinyl)-2(1H)-pyridinones
US4004012A (en) * 1975-10-14 1977-01-18 Sterling Drug Inc. 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones

Also Published As

Publication number Publication date
PT72264B (en) 1981-11-05
NZ195878A (en) 1982-11-23
ZA807864B (en) 1981-12-30
AT373876B (de) 1984-02-27
IT1134860B (it) 1986-08-20
IE802619L (en) 1981-06-26
SE8009134L (sv) 1981-06-27
GB2066251A (en) 1981-07-08
FR2472563A1 (fr) 1981-07-03
JPS56103164A (en) 1981-08-18
BE886766A (fr) 1981-06-19
NL8006824A (nl) 1981-07-16
AU6556680A (en) 1981-07-02
US4271168A (en) 1981-06-02
DK550480A (da) 1981-06-27
IL61690A0 (en) 1981-01-30
ES498144A0 (es) 1981-12-01
NO803911L (no) 1981-06-29
IL61690A (en) 1983-11-30
KR830004291A (ko) 1983-07-09
IE50523B1 (en) 1986-04-30
ATA629380A (de) 1983-07-15
GB2066251B (en) 1983-10-19
FI803973L (fi) 1981-06-27
PH15974A (en) 1983-05-11
PT72264A (en) 1981-01-01
ES8201136A1 (es) 1981-12-01
DE3048635A1 (de) 1981-09-17
AR230435A1 (es) 1984-04-30
CA1131231A (en) 1982-09-07
IT8026876A0 (it) 1980-12-22

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