BE886766A - 3-acylamino-5(pyridinyl)-2(1h)-pyridinones, leur preparation et leur utilisation comme agents cardiotoniques - Google Patents

3-acylamino-5(pyridinyl)-2(1h)-pyridinones, leur preparation et leur utilisation comme agents cardiotoniques

Info

Publication number: BE886766A
Authority: BE; Belgium
Prior art keywords: pyridinones; acylamino; pyridinyl; preparation; cardiotonic agents
Prior art date: 1979-12-26

Application number

BE1/10084A

Other languages

English (en)

Inventor

G Y Lesher

C J Opalka

Original Assignee

Sterling Drug Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-12-26

Filing date

1980-12-19

Publication date

1981-06-19

1980-12-19 Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc

1981-06-19 Publication of BE886766A publication Critical patent/BE886766A/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)

BE1/10084A 1979-12-26 1980-12-19 3-acylamino-5(pyridinyl)-2(1h)-pyridinones, leur preparation et leur utilisation comme agents cardiotoniques BE886766A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/106,764 US4271168A (en)	1979-12-26	1979-12-26	Selected 3-acylamino-5-[4(or 3)-pyridinyl]-2(1H)-pyridinones

Publications (1)

Publication Number	Publication Date
BE886766A true BE886766A (fr)	1981-06-19

Family

ID=22313122

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE1/10084A BE886766A (fr)	1979-12-26	1980-12-19	3-acylamino-5(pyridinyl)-2(1h)-pyridinones, leur preparation et leur utilisation comme agents cardiotoniques

Country Status (25)

Country	Link
US (1)	US4271168A (fr)
JP (1)	JPS56103164A (fr)
KR (1)	KR830004291A (fr)
AR (1)	AR230435A1 (fr)
AT (1)	AT373876B (fr)
AU (1)	AU6556680A (fr)
BE (1)	BE886766A (fr)
CA (1)	CA1131231A (fr)
DE (1)	DE3048635A1 (fr)
DK (1)	DK550480A (fr)
ES (1)	ES8201136A1 (fr)
FI (1)	FI803973L (fr)
FR (1)	FR2472563A1 (fr)
GB (1)	GB2066251B (fr)
IE (1)	IE50523B1 (fr)
IL (1)	IL61690A (fr)
IT (1)	IT1134860B (fr)
LU (1)	LU83032A1 (fr)
NL (1)	NL8006824A (fr)
NO (1)	NO803911L (fr)
NZ (1)	NZ195878A (fr)
PH (1)	PH15974A (fr)
PT (1)	PT72264B (fr)
SE (1)	SE8009134L (fr)
ZA (1)	ZA807864B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS587411A (ja) *	1981-07-07	1983-01-17	Mitsui Toatsu Chem Inc	薄肉射出成形用プロピレン／エチレン共重合体の製造方法
US4432979A (en) *	1981-10-26	1984-02-21	William H. Rorer, Inc.	Pyridone compounds
BE896678A (fr) *	1982-05-18	1983-11-07	Sandoz Sa	Nouveaux derives de la 2 (1h)-pyridinone, leur preparation et leur utilisation comme medicaments.
IT8367883A0 (it) *	1982-08-23	1983-08-22	Rorer Int Overseas	Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche
US4666913A (en) *	1985-11-22	1987-05-19	William H. Rorer, Inc.	Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses
KR20070095952A (ko) *	2004-12-16	2007-10-01	버텍스 파마슈티칼스 인코포레이티드	염증성 질환, 증식성 질환 및 면역학적으로 매개된 질환치료용 Ｔｅｃ 계열 단백질 키나제의 억제제로서 유용한피리드-2-온

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4072746A (en) *	1975-10-14	1978-02-07	Sterling Drug Inc.	3-Amino-5-(pyridinyl)-2(1H)-pyridinones
US4004012A (en) *	1975-10-14	1977-01-18	Sterling Drug Inc.	3-Cyano-5-(pyridinyl)-2(1H)-pyridinones

1979
- 1979-12-26 US US06/106,764 patent/US4271168A/en not_active Expired - Lifetime
1980
- 1980-12-11 IL IL61690A patent/IL61690A/xx unknown
- 1980-12-12 IE IE2619/80A patent/IE50523B1/en unknown
- 1980-12-16 NL NL8006824A patent/NL8006824A/nl not_active Application Discontinuation
- 1980-12-17 ZA ZA00807864A patent/ZA807864B/xx unknown
- 1980-12-18 PH PH25005A patent/PH15974A/en unknown
- 1980-12-18 NZ NZ195878A patent/NZ195878A/xx unknown
- 1980-12-19 FI FI803973A patent/FI803973L/fi not_active Application Discontinuation
- 1980-12-19 AU AU65566/80A patent/AU6556680A/en not_active Abandoned
- 1980-12-19 BE BE1/10084A patent/BE886766A/fr not_active IP Right Cessation
- 1980-12-22 FR FR8027218A patent/FR2472563A1/fr active Pending
- 1980-12-22 IT IT26876/80A patent/IT1134860B/it active
- 1980-12-22 NO NO803911A patent/NO803911L/no unknown
- 1980-12-22 PT PT72264A patent/PT72264B/pt unknown
- 1980-12-23 SE SE8009134A patent/SE8009134L/xx not_active Application Discontinuation
- 1980-12-23 AR AR283770A patent/AR230435A1/es active
- 1980-12-23 LU LU83032A patent/LU83032A1/fr unknown
- 1980-12-23 DK DK550480A patent/DK550480A/da not_active Application Discontinuation
- 1980-12-23 DE DE19803048635 patent/DE3048635A1/de not_active Withdrawn
- 1980-12-23 CA CA367,452A patent/CA1131231A/fr not_active Expired
- 1980-12-23 GB GB8041225A patent/GB2066251B/en not_active Expired
- 1980-12-23 AT AT0629380A patent/AT373876B/de not_active IP Right Cessation
- 1980-12-24 KR KR1019800004918A patent/KR830004291A/ko unknown
- 1980-12-24 ES ES498144A patent/ES8201136A1/es not_active Expired
- 1980-12-26 JP JP18947780A patent/JPS56103164A/ja active Pending

Also Published As

Publication number	Publication date
PT72264B (en)	1981-11-05
NZ195878A (en)	1982-11-23
ZA807864B (en)	1981-12-30
AT373876B (de)	1984-02-27
IT1134860B (it)	1986-08-20
IE802619L (en)	1981-06-26
SE8009134L (sv)	1981-06-27
GB2066251A (en)	1981-07-08
FR2472563A1 (fr)	1981-07-03
JPS56103164A (en)	1981-08-18
NL8006824A (nl)	1981-07-16
AU6556680A (en)	1981-07-02
LU83032A1 (fr)	1981-07-23
US4271168A (en)	1981-06-02
DK550480A (da)	1981-06-27
IL61690A0 (en)	1981-01-30
ES498144A0 (es)	1981-12-01
NO803911L (no)	1981-06-29
IL61690A (en)	1983-11-30
KR830004291A (ko)	1983-07-09
IE50523B1 (en)	1986-04-30
ATA629380A (de)	1983-07-15
GB2066251B (en)	1983-10-19
FI803973L (fi)	1981-06-27
PH15974A (en)	1983-05-11
PT72264A (en)	1981-01-01
ES8201136A1 (es)	1981-12-01
DE3048635A1 (de)	1981-09-17
AR230435A1 (es)	1984-04-30
CA1131231A (fr)	1982-09-07
IT8026876A0 (it)	1980-12-22

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BE887953A (fr)	1981-09-16	Pyrazolopyridinones et pyridinylnicotinates, leur preparation et leur utilisation comme agents cardiotoniques

Legal Events

Date

Code

Title

Description

1985-06-30

RE

Patent lapsed

Owner name: STERLING DRUG INC.

Effective date: 19841219