JPS5533500A - 3,7-disubstituted-3-cephem-4-carboxylic acid, its salt, their preparation, and preventive and remedy for microbism - Google Patents

3,7-disubstituted-3-cephem-4-carboxylic acid, its salt, their preparation, and preventive and remedy for microbism

Info

Publication number
JPS5533500A
JPS5533500A JP11211079A JP11211079A JPS5533500A JP S5533500 A JPS5533500 A JP S5533500A JP 11211079 A JP11211079 A JP 11211079A JP 11211079 A JP11211079 A JP 11211079A JP S5533500 A JPS5533500 A JP S5533500A
Authority
JP
Japan
Prior art keywords
compound
formula
cephem
carboxylic acid
protected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11211079A
Other languages
English (en)
Other versions
JPS6361954B2 (ja
Inventor
Takao Takatani
Takashi Masugi
Hisashi Takasugi
Hiromu Kawachi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS5533500A publication Critical patent/JPS5533500A/ja
Publication of JPS6361954B2 publication Critical patent/JPS6361954B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP11211079A 1978-08-31 1979-08-31 3,7-disubstituted-3-cephem-4-carboxylic acid, its salt, their preparation, and preventive and remedy for microbism Granted JPS5533500A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7835195 1978-08-31

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP63001678A Division JPS63239277A (ja) 1988-01-07 1988-01-07 チアゾール酢酸誘導体

Publications (2)

Publication Number Publication Date
JPS5533500A true JPS5533500A (en) 1980-03-08
JPS6361954B2 JPS6361954B2 (ja) 1988-11-30

Family

ID=10499378

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11211079A Granted JPS5533500A (en) 1978-08-31 1979-08-31 3,7-disubstituted-3-cephem-4-carboxylic acid, its salt, their preparation, and preventive and remedy for microbism

Country Status (9)

Country Link
JP (1) JPS5533500A (ja)
BE (1) BE878433A (ja)
CH (1) CH642663A5 (ja)
DE (1) DE2934682A1 (ja)
ES (3) ES483676A1 (ja)
FR (1) FR2434812A1 (ja)
GB (1) GB2083820B (ja)
NL (1) NL7906497A (ja)
SE (1) SE7907159L (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5585594A (en) * 1978-11-13 1980-06-27 Fujisawa Pharmaceut Co Ltd Cephem compound and their preparation
JPS5973610A (ja) * 1982-10-20 1984-04-25 Tokico Ltd 油圧緩衝器
JPS61155389A (ja) * 1984-12-20 1986-07-15 Fujisawa Pharmaceut Co Ltd 新規セフエム化合物およびその製造法
JPH02111751A (ja) * 1981-05-07 1990-04-24 Fujisawa Pharmaceut Co Ltd 新規なカルボン酸誘導体
JPH02223544A (ja) * 1982-01-22 1990-09-05 Fujisawa Pharmaceut Co Ltd 酪酸化合物

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
JPS6011917B2 (ja) * 1981-04-09 1985-03-28 山之内製薬株式会社 新規なセファロスポリン化合物
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52125190A (en) * 1976-04-12 1977-10-20 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation
JPS549296A (en) * 1977-04-02 1979-01-24 Hoechst Ag Cephem derivative and its preparation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK159154C (da) * 1975-02-24 1991-02-11 Takeda Chemical Industries Ltd Fremgangsmaade til fremstilling af cephalosporinderivater eller salte deraf
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
FR2381053A1 (fr) * 1977-02-18 1978-09-15 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
DE2804040C3 (de) * 1978-01-31 1981-03-19 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von Cephemverbindungen
SE7901262L (sv) * 1978-02-15 1979-08-16 Fujisawa Pharmaceutical Co 3,7-disubstituerade 3-cefem-4-karboxylsyraforeningar och forfarande for deras framstellning
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52125190A (en) * 1976-04-12 1977-10-20 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation
JPS549296A (en) * 1977-04-02 1979-01-24 Hoechst Ag Cephem derivative and its preparation

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5585594A (en) * 1978-11-13 1980-06-27 Fujisawa Pharmaceut Co Ltd Cephem compound and their preparation
JPH0144713B2 (ja) * 1978-11-13 1989-09-29 Fujisawa Pharmaceutical Co
JPH02111751A (ja) * 1981-05-07 1990-04-24 Fujisawa Pharmaceut Co Ltd 新規なカルボン酸誘導体
JPH02223544A (ja) * 1982-01-22 1990-09-05 Fujisawa Pharmaceut Co Ltd 酪酸化合物
JPS5973610A (ja) * 1982-10-20 1984-04-25 Tokico Ltd 油圧緩衝器
JPH0260900B2 (ja) * 1982-10-20 1990-12-18 Tokico Ltd
JPS61155389A (ja) * 1984-12-20 1986-07-15 Fujisawa Pharmaceut Co Ltd 新規セフエム化合物およびその製造法

Also Published As

Publication number Publication date
FR2434812B1 (ja) 1983-05-13
FR2434812A1 (fr) 1980-03-28
DE2934682A1 (de) 1980-03-13
ES483676A1 (es) 1980-09-01
NL7906497A (nl) 1980-03-04
ES490890A0 (es) 1980-12-16
JPS6361954B2 (ja) 1988-11-30
CH642663A5 (de) 1984-04-30
GB2083820A (en) 1982-03-31
BE878433A (fr) 1980-02-25
ES8102143A1 (es) 1980-12-16
ES490891A0 (es) 1980-12-16
SE7907159L (sv) 1980-03-01
GB2083820B (en) 1983-02-16
ES8102109A1 (es) 1980-12-16

Similar Documents

Publication Publication Date Title
JPS5368796A (en) Syn-isomer of 3,7-disubstd.-3-cephem-4-carboxylic acids, and their preventingor treating agents containing their salts as active constituent againstdiseases caused by bacterial infection
JPS5520800A (en) Cephem compounds, their salts, their preparation, and preventive or remedy for microbism containing the same as the effective component
JPS5686187A (en) 7-acylamino-3-vinylcephalosporanic acid derivative and its preparation
JPS54132592A (en) 3,7-di-substituted-3-cephem-4-carboxylic acid derivative, its salt, and their preparation
JPS55105689A (en) Novel cephem and cepham compounds, their preparation and preventive and remedy for microbism
JPS5777689A (en) Novel cephen compound, or its salt, its preparation, and preventive it as active ingredient
JPS5533500A (en) 3,7-disubstituted-3-cephem-4-carboxylic acid, its salt, their preparation, and preventive and remedy for microbism
JPS5798288A (en) Novel cephem compound or its salt, their preparation, and preventive and remedy for bacteriosis containing said compound as active component
JPS55115892A (en) 3-phosphonocephalosporanic acid derivative, its preparation, and medicine containing the same
JPS5547688A (en) Novel cephem compound and its preparation
JPS5535096A (en) 3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent
JPS54117493A (en) 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, its preparation, and preventives and remedies for microbism consisting mainly of them
JPS5799592A (en) Novel cephalosporins
ES8200371A1 (es) Procedimiento para la preparacion de derivados tiazolil-n- substituidos de cefalosporinas oxi-imino-substituidas
JPS5547690A (en) Cephem compound, its salt, their preparation, and preventives and remedies for microbism comprising them as active constituents
JPS55164690A (en) 7- 2- 2-aminothiazole-4-yl 3-hydroxypropionamide cephalosporin compound and its preparation
JPS54117494A (en) Cephalosporin compound and its preparation
JPS5649389A (en) Novel cephem compound, its preparation, and preventive and remedy for microbism
JPS57136587A (en) Preparation of cephalosporin derivative
JPS56115788A (en) Azetidinone derivative and its preparation
JPS5549384A (en) Novel antibacterial compound
JPS57163386A (en) Cephalosporin derivative and its production
JPS5625188A (en) 7alpha-methoxycephalosporin
JPS5645461A (en) Alpha-amino acid derivative
JPS57156496A (en) Preparation of cephalosporin derivative