FR2381053A1 - Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments - Google Patents

Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Info

Publication number
FR2381053A1
FR2381053A1 FR7704745A FR7704745A FR2381053A1 FR 2381053 A1 FR2381053 A1 FR 2381053A1 FR 7704745 A FR7704745 A FR 7704745A FR 7704745 A FR7704745 A FR 7704745A FR 2381053 A1 FR2381053 A1 FR 2381053A1
Authority
FR
France
Prior art keywords
aminothiazolyl
thiomethyl
thiadiazolyl
application
preparation process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7704745A
Other languages
English (en)
Other versions
FR2381053B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7704745A priority Critical patent/FR2381053A1/fr
Priority to SE7800790A priority patent/SE434268B/sv
Priority to FI780444A priority patent/FI69468C/fi
Priority to ZA00780847A priority patent/ZA78847B/xx
Priority to IL54043A priority patent/IL54043A/xx
Priority to SU782578251A priority patent/SU841590A3/ru
Priority to DE19782806226 priority patent/DE2806226A1/de
Priority to YU336/78A priority patent/YU41583B/xx
Priority to DK68978A priority patent/DK68978A/da
Priority to GR55474A priority patent/GR71703B/el
Priority to CH178978A priority patent/CH633016A5/fr
Priority to CA297,248A priority patent/CA1132537A/fr
Priority to BE185267A priority patent/BE864074A/fr
Priority to AU33375/78A priority patent/AU516076B2/en
Priority to HU78RO963A priority patent/HU181961B/hu
Priority to NL7801834A priority patent/NL7801834A/xx
Priority to PT67673A priority patent/PT67673B/fr
Priority to JP1666578A priority patent/JPS53108996A/ja
Priority to LU79080A priority patent/LU79080A1/fr
Priority to ES467090A priority patent/ES467090A1/es
Priority to IE364/78A priority patent/IE46651B1/en
Priority to AT120978A priority patent/AT355722B/de
Priority to GB6621/78A priority patent/GB1575180A/en
Publication of FR2381053A1 publication Critical patent/FR2381053A1/fr
Priority to ES475956A priority patent/ES475956A1/es
Priority to AT127379A priority patent/AT358177B/de
Application granted granted Critical
Publication of FR2381053B1 publication Critical patent/FR2381053B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention a pour objet les produits de formule :
FR7704745A 1977-02-18 1977-02-18 Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments Granted FR2381053A1 (fr)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FR7704745A FR2381053A1 (fr) 1977-02-18 1977-02-18 Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
SE7800790A SE434268B (sv) 1977-02-18 1978-01-23 Sett att framstella nya oximderivat av 3-tiadiazolyl-tiometyl-7-aminotiazolyl-acetamidocefalosporansyra
FI780444A FI69468C (fi) 1977-02-18 1978-02-10 Foerfarande foer framstaellning av nya farmakologiskt vaerdefulla oximderivat av 3-tiadiazolyl-tiometyl-7-amino-tiazolylacetamido-cefalosporansyra
ZA00780847A ZA78847B (en) 1977-02-18 1978-02-13 New oxime derivatives of 3-thiadiazolyl thiomethyl 7-amino thiazolyl acetamido cephalosporanic acid,process for preparing them and pharmaceutical compositions
IL54043A IL54043A (en) 1977-02-18 1978-02-13 Oxime derivatives of 3-thiadiazolyl thiomethyl 7-amino thiazolyl acetamido cephalosporanic acid,process for preparing them and pharmaceutical compositions comprising them
SU782578251A SU841590A3 (ru) 1977-02-18 1978-02-14 Способ получени производных - -( -АМиНО- -ТиАзОлил)- - АлКОКСииМиНОАцЕТАМидО - -( - ТиАдиАзОл- -илТиОМЕТил)цЕф- -EM-- КАРбОНОВОй КиСлОТы или иХ СОлЕйС щЕлОчНыМи МЕТАллАМи, B ВидЕ СиН-изО-MEPOB
DE19782806226 DE2806226A1 (de) 1977-02-18 1978-02-14 Oximderivate der 3-thiadiazolylthiomethyl-7-aminothiazolyl-acetamido- cephalosporansaeure, ihr herstellungsverfahren sowie pharmazeutische zusammensetzungen
YU336/78A YU41583B (en) 1977-02-18 1978-02-14 Process for obtaining new oxime derivatives of 3-thiadiazolyl-thiomethyl-7-amino-thiazolyl acetamido cephalospornic acid
GR55474A GR71703B (fr) 1977-02-18 1978-02-16
DK68978A DK68978A (da) 1977-02-18 1978-02-16 Fremgangsmaade til fremstilling af oximderivater af 3-thiadiazolythiomethyl-7-aminothiazolylacetamidocephalosporansyre
ES467090A ES467090A1 (es) 1977-02-18 1978-02-17 Procedimiento de preparacion de nuevas oximas derivadas del acido 3-tiadiazolil-tiometil-7-amino-tiazolil-acetamido-ce- falosporanico
BE185267A BE864074A (fr) 1977-02-18 1978-02-17 Nouvelles oximes derivees de l'acide 3-thia-diazolyl thiomethyl 7-amino thiazolyl, acetamido cephalosporanique, procede de preparation et compositions pharmaceutiques
CH178978A CH633016A5 (en) 1977-02-18 1978-02-17 Oximes derived from 3-(thiadiazolylthiomethyl)-7-(aminothiazolylacetamido)cephalosporanic acid, process of preparation and pharmaceutical compositions
HU78RO963A HU181961B (en) 1977-02-18 1978-02-17 Process for producing new oxime derivatives of 3-thiadiazolythio-methyl-7-aminothiazolylacetamido-ceph-3-eme-4-carboxylic acids
NL7801834A NL7801834A (nl) 1977-02-18 1978-02-17 Nieuwe oximen van 3-thiadiazolyl thiomethyl 7-amino thiazolyl aceetamido cefalosporaanzuur, werkwijze voor hun bereiding en farmaceutische preparaten.
PT67673A PT67673B (fr) 1977-02-18 1978-02-17 Procede de preparation de nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-amino thiazolyl acetamidecephalosporanique
JP1666578A JPS53108996A (en) 1977-02-18 1978-02-17 33thiadiazolylthiomethyll77 aminothiazolylacetamide cephalospolanate process for preparing same and pharmaceutical composition
LU79080A LU79080A1 (fr) 1977-02-18 1978-02-17 Procede de preparation de nouvelles oximes derivees de 1'acide 3-thiadiazolyl thiomethyl 7-amino thiazolyl acetamido cephalosporanique
CA297,248A CA1132537A (fr) 1977-02-18 1978-02-17 Procede de preparation de nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique
AU33375/78A AU516076B2 (en) 1977-02-18 1978-02-17 Cephalosporins
IE364/78A IE46651B1 (en) 1977-02-18 1978-02-20 New oxime derivatives of 3-thiadiazolyl thiomethyl-7-aminothiazolylacetamido-cephalosporanic acid,processes for preparing them and pharmaceutical compositions containing them
AT120978A AT355722B (de) 1977-02-18 1978-02-20 Verfahren zur herstellung von neuen oxim- derivaten der 3-thiadiazolyl -thiomethyl-7-amino-thiazolyl-acetamido- cephalosporansaeure
GB6621/78A GB1575180A (en) 1977-02-18 1978-02-20 Oxime derivatives of 3-thiadiazolylthiomethyl-7-aminothiazolylacetamido-cephalosporanic acid processes for preparing them and pharmaceutical compositions containing them
ES475956A ES475956A1 (es) 1977-02-18 1978-12-13 Procedimiento de preparacion de nuevas oximas derivadas del acido 3-tiadiazolil-tiometil-7-amino-tiazolil-acetamido-ce- falosporanico
AT127379A AT358177B (de) 1977-02-18 1979-02-19 Verfahren zur herstellung von neuen oxim- derivaten der 3-thiadiazolyl-thiomethyl-7- -amino-thiazolyl-acetamido-cephalosporansaeure

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7704745A FR2381053A1 (fr) 1977-02-18 1977-02-18 Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
FR2381053A1 true FR2381053A1 (fr) 1978-09-15
FR2381053B1 FR2381053B1 (fr) 1979-06-01

Family

ID=9186946

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7704745A Granted FR2381053A1 (fr) 1977-02-18 1977-02-18 Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Country Status (23)

Country Link
JP (1) JPS53108996A (fr)
AT (1) AT355722B (fr)
AU (1) AU516076B2 (fr)
BE (1) BE864074A (fr)
CA (1) CA1132537A (fr)
CH (1) CH633016A5 (fr)
DE (1) DE2806226A1 (fr)
DK (1) DK68978A (fr)
ES (2) ES467090A1 (fr)
FI (1) FI69468C (fr)
FR (1) FR2381053A1 (fr)
GB (1) GB1575180A (fr)
GR (1) GR71703B (fr)
HU (1) HU181961B (fr)
IE (1) IE46651B1 (fr)
IL (1) IL54043A (fr)
LU (1) LU79080A1 (fr)
NL (1) NL7801834A (fr)
PT (1) PT67673B (fr)
SE (1) SE434268B (fr)
SU (1) SU841590A3 (fr)
YU (1) YU41583B (fr)
ZA (1) ZA78847B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2488258A1 (fr) * 1980-08-11 1982-02-12 American Cyanamid Co Acide 7-beta-(alpha-syn-methoxyimino-alpha - (2-aminothiazol-4-yl) - acetamino)-3-((1,2,3-thiadiazol-5-ylthio) methyl)-3-cepheme-4-carboxylique et derives alkyliques en c1-c6 de celui-ci, compositions contenant ces composes et leurs applications

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878433A (fr) * 1978-08-31 1980-02-25 Fujisawa Pharmaceutical Co Procede de preparation de derives d'acide 3-cephem-4-carboxylique 3,7-disubstitue, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
US4761409A (en) * 1984-08-16 1988-08-02 Sumitomo Pharmaceuticals Company, Limited Cephem derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2137900A1 (fr) * 1971-05-14 1972-12-29 Glaxo Lab Ltd

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2137900A1 (fr) * 1971-05-14 1972-12-29 Glaxo Lab Ltd
FR2137899A1 (fr) * 1971-05-14 1972-12-29 Glaxo Lab Ltd

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2488258A1 (fr) * 1980-08-11 1982-02-12 American Cyanamid Co Acide 7-beta-(alpha-syn-methoxyimino-alpha - (2-aminothiazol-4-yl) - acetamino)-3-((1,2,3-thiadiazol-5-ylthio) methyl)-3-cepheme-4-carboxylique et derives alkyliques en c1-c6 de celui-ci, compositions contenant ces composes et leurs applications

Also Published As

Publication number Publication date
IE46651B1 (en) 1983-08-10
ES467090A1 (es) 1979-06-01
ES475956A1 (es) 1979-12-16
DK68978A (da) 1978-08-19
BE864074A (fr) 1978-08-17
YU33678A (en) 1983-01-21
CA1132537A (fr) 1982-09-28
FI69468C (fi) 1986-02-10
PT67673B (fr) 1980-03-03
AT355722B (de) 1980-03-25
IL54043A0 (en) 1978-04-30
ATA120978A (de) 1979-08-15
FI69468B (fi) 1985-10-31
SE7800790L (sv) 1978-08-18
NL7801834A (nl) 1978-08-22
FI780444A (fi) 1978-08-19
GR71703B (fr) 1983-06-21
FR2381053B1 (fr) 1979-06-01
YU41583B (en) 1987-10-31
SU841590A3 (ru) 1981-06-23
HU181961B (en) 1983-11-28
GB1575180A (en) 1980-09-17
JPS53108996A (en) 1978-09-22
SE434268B (sv) 1984-07-16
ZA78847B (en) 1979-03-28
IL54043A (en) 1983-02-23
DE2806226A1 (de) 1978-08-24
LU79080A1 (fr) 1978-09-28
AU3337578A (en) 1979-08-23
CH633016A5 (en) 1982-11-15
PT67673A (fr) 1978-03-01
IE780364L (en) 1978-08-18
AU516076B2 (en) 1981-05-14

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