ES8200371A1 - Procedimiento para la preparacion de derivados tiazolil-n- substituidos de cefalosporinas oxi-imino-substituidas - Google Patents
Procedimiento para la preparacion de derivados tiazolil-n- substituidos de cefalosporinas oxi-imino-substituidasInfo
- Publication number
- ES8200371A1 ES8200371A1 ES497531A ES497531A ES8200371A1 ES 8200371 A1 ES8200371 A1 ES 8200371A1 ES 497531 A ES497531 A ES 497531A ES 497531 A ES497531 A ES 497531A ES 8200371 A1 ES8200371 A1 ES 8200371A1
- Authority
- ES
- Spain
- Prior art keywords
- substituted
- imino
- oxy
- bacterial agents
- cephalosporins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE TIAZOLIL-N-SUSTITUIDOS DE CEFALOSPORINAS OXI-IMINO-SUSTITUIDAS, DE FORMULA (I), Y SUS SALES, DONDE R, R3 E Y PUEDEN SER DIFERENTES RADICALES; R1 ES HIDROGENO O UN GRUPO AMINO PROTECTOR, X ES UN GRUPO CARBOXILICO LIBRE O ESTERIFICADO Y N ES 0, 1 O 2. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), O UN DERIVADO REACTIVO DEL MISMO DONDE E ES AMINO, -N=C=O O -N=C=S; CON UN COMPUESTO DE FORMULA (III) O CON UN DERIVADO REACTIVO DEL MISMO. EXISTEN DIFERENTES ALERNATIVAS DE REACCION PARTIENDO DE DIVERSOS COMPUESTOS DE FORMULAR (II) Y (III). DE APLICACION EN EL TRATAMIENTO DE INFECCIONES CAUSADAS POR MICROORGANISMOS GRAM-POSITIVOS Y GRAN-NEGATIVOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7942269 | 1979-12-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES497531A0 ES497531A0 (es) | 1981-10-16 |
ES8200371A1 true ES8200371A1 (es) | 1981-10-16 |
Family
ID=10509695
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES497531A Expired ES8200371A1 (es) | 1979-12-07 | 1980-12-06 | Procedimiento para la preparacion de derivados tiazolil-n- substituidos de cefalosporinas oxi-imino-substituidas |
Country Status (24)
Country | Link |
---|---|
US (1) | US4358448A (es) |
JP (1) | JPS5692291A (es) |
AT (1) | AT369747B (es) |
AU (1) | AU532251B2 (es) |
BE (1) | BE886534A (es) |
CA (1) | CA1177481A (es) |
CS (1) | CS221283B2 (es) |
DE (1) | DE3043865A1 (es) |
DK (1) | DK522580A (es) |
ES (1) | ES8200371A1 (es) |
FI (1) | FI803627L (es) |
FR (1) | FR2475046A1 (es) |
GR (1) | GR72925B (es) |
IE (1) | IE50582B1 (es) |
IL (1) | IL61458A0 (es) |
IT (1) | IT1193392B (es) |
LU (1) | LU82979A1 (es) |
NL (1) | NL8006337A (es) |
NO (1) | NO803695L (es) |
NZ (1) | NZ195675A (es) |
PH (1) | PH17385A (es) |
PT (1) | PT72173B (es) |
SE (1) | SE8008540L (es) |
ZA (1) | ZA807281B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES485938A1 (es) * | 1978-11-15 | 1980-07-01 | Glaxo Group Ltd | Un procedimiento para la preparacion de antibioticos de ce- falosporina |
IL74822A (en) * | 1984-04-17 | 1989-06-30 | Daiichi Seiyaku Co | Cephalosporin derivatives and salts thereof and their preparation |
GB8410991D0 (en) * | 1984-04-30 | 1984-06-06 | Glaxo Group Ltd | Process |
GB8410993D0 (en) * | 1984-04-30 | 1984-06-06 | Glaxo Group Ltd | Process |
ATE103923T1 (de) * | 1985-12-13 | 1994-04-15 | Takeda Chemical Industries Ltd | Antibakterielle verbindungen, ihre herstellung und verwendung. |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2345153A1 (fr) * | 1976-03-25 | 1977-10-21 | Roussel Uclaf | Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
GB1576625A (en) * | 1976-04-12 | 1980-10-08 | Fujisawa Pharmaceutical Co | Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof |
JPS5946237B2 (ja) * | 1976-04-02 | 1984-11-10 | 武田薬品工業株式会社 | セフアロスポリン誘導体およびその製造法 |
DK162391C (da) * | 1976-04-12 | 1992-03-09 | Fujisawa Pharmaceutical Co | Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser |
FR2361895A1 (fr) * | 1976-08-20 | 1978-03-17 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 3-carbamoyloxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
FR2384779A1 (fr) * | 1977-03-25 | 1978-10-20 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 3-chloro ou 3-methoxy 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
DE2715495A1 (de) * | 1977-04-06 | 1978-10-19 | Cusi Lab | Neue cephalosporinverbindungen, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
JPS609719B2 (ja) * | 1977-08-06 | 1985-03-12 | 武田薬品工業株式会社 | セフアロスポリン誘導体およびその製造法 |
FR2387235A1 (fr) | 1978-01-23 | 1978-11-10 | Fujisawa Pharmaceutical Co | Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne |
FR2432521A1 (fr) * | 1978-03-31 | 1980-02-29 | Roussel Uclaf | Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
-
1980
- 1980-11-11 IL IL61458A patent/IL61458A0/xx unknown
- 1980-11-12 US US06/206,078 patent/US4358448A/en not_active Expired - Lifetime
- 1980-11-13 AU AU64343/80A patent/AU532251B2/en not_active Ceased
- 1980-11-18 PH PH24875A patent/PH17385A/en unknown
- 1980-11-20 NL NL8006337A patent/NL8006337A/nl not_active Application Discontinuation
- 1980-11-21 DE DE19803043865 patent/DE3043865A1/de not_active Ceased
- 1980-11-21 FI FI803627A patent/FI803627L/fi not_active Application Discontinuation
- 1980-11-21 ZA ZA00807281A patent/ZA807281B/xx unknown
- 1980-11-24 CA CA000365302A patent/CA1177481A/en not_active Expired
- 1980-11-28 NZ NZ195675A patent/NZ195675A/xx unknown
- 1980-12-03 IT IT26400/80A patent/IT1193392B/it active
- 1980-12-04 CS CS808518A patent/CS221283B2/cs unknown
- 1980-12-05 BE BE0/203076A patent/BE886534A/fr not_active IP Right Cessation
- 1980-12-05 LU LU82979A patent/LU82979A1/fr unknown
- 1980-12-05 PT PT72173A patent/PT72173B/pt unknown
- 1980-12-05 DK DK522580A patent/DK522580A/da not_active Application Discontinuation
- 1980-12-05 JP JP17253380A patent/JPS5692291A/ja active Pending
- 1980-12-05 IE IE2552/80A patent/IE50582B1/en unknown
- 1980-12-05 AT AT0596380A patent/AT369747B/de not_active IP Right Cessation
- 1980-12-05 SE SE8008540A patent/SE8008540L/xx not_active Application Discontinuation
- 1980-12-05 NO NO803695A patent/NO803695L/no unknown
- 1980-12-05 GR GR63564A patent/GR72925B/el unknown
- 1980-12-05 FR FR8025919A patent/FR2475046A1/fr active Granted
- 1980-12-06 ES ES497531A patent/ES8200371A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
NZ195675A (en) | 1983-05-31 |
PH17385A (en) | 1984-08-08 |
IE50582B1 (en) | 1986-05-14 |
CS221283B2 (en) | 1983-04-29 |
LU82979A1 (fr) | 1981-03-26 |
SE8008540L (sv) | 1981-06-08 |
DK522580A (da) | 1981-06-08 |
PT72173A (en) | 1981-01-01 |
GR72925B (es) | 1984-01-11 |
DE3043865A1 (de) | 1981-09-03 |
FR2475046A1 (fr) | 1981-08-07 |
ES497531A0 (es) | 1981-10-16 |
IE802552L (en) | 1981-06-07 |
AU6434380A (en) | 1981-06-11 |
IT1193392B (it) | 1988-06-15 |
IL61458A0 (en) | 1980-12-31 |
AU532251B2 (en) | 1983-09-22 |
JPS5692291A (en) | 1981-07-25 |
PT72173B (en) | 1983-01-10 |
BE886534A (fr) | 1981-06-05 |
CA1177481A (en) | 1984-11-06 |
NO803695L (no) | 1981-06-09 |
FR2475046B1 (es) | 1984-07-13 |
ATA596380A (de) | 1982-06-15 |
ZA807281B (en) | 1981-11-25 |
NL8006337A (nl) | 1981-07-01 |
FI803627L (fi) | 1981-06-08 |
US4358448A (en) | 1982-11-09 |
AT369747B (de) | 1983-01-25 |
IT8026400A0 (it) | 1980-12-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20001009 |