JPH01250353A - ９−アシルアミノ−テトラヒドロアクリジン誘導体及び該誘導体を有効成分とする記憶障害改善剤 - Google Patents

９−アシルアミノ−テトラヒドロアクリジン誘導体及び該誘導体を有効成分とする記憶障害改善剤

Info

Publication number
JPH01250353A
JPH01250353A JP63283351A JP28335188A JPH01250353A JP H01250353 A JPH01250353 A JP H01250353A JP 63283351 A JP63283351 A JP 63283351A JP 28335188 A JP28335188 A JP 28335188A JP H01250353 A JPH01250353 A JP H01250353A
Authority
JP
Japan
Prior art keywords
formulas
formula
tables
mathematical
chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP63283351A
Other languages
English (en)
Japanese (ja)
Inventor
Shuji Morita
修司 森田
Kenichi Saito
健一 斎藤
Kunihiro Ninomiya
二宮　邦博
Akihiro Tobe
戸部　昭広
Kazumasa Nitta
新田　一誠
Mamoru Kanno
管野　守
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP63283351A priority Critical patent/JPH01250353A/ja
Priority to HU886151A priority patent/HU202499B/hu
Priority to US07/279,051 priority patent/US4985430A/en
Priority to DE3889302T priority patent/DE3889302T2/de
Priority to AT8888403058T priority patent/ATE104966T1/de
Priority to EP88403058A priority patent/EP0319429B1/en
Priority to KR1019880016146A priority patent/KR0128975B1/ko
Publication of JPH01250353A publication Critical patent/JPH01250353A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C07D219/12—Amino-alkylamino radicals attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP63283351A 1987-12-03 1988-11-09 ９−アシルアミノ−テトラヒドロアクリジン誘導体及び該誘導体を有効成分とする記憶障害改善剤 Pending JPH01250353A (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP63283351A JPH01250353A (ja) 1987-12-03 1988-11-09 ９−アシルアミノ−テトラヒドロアクリジン誘導体及び該誘導体を有効成分とする記憶障害改善剤
HU886151A HU202499B (en) 1987-12-03 1988-12-02 Process for producing 9-(acylamino)-tetrahydroacridine derivatives and pharmaceutical compositions containing them as active components
US07/279,051 US4985430A (en) 1987-12-03 1988-12-02 9-acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient
DE3889302T DE3889302T2 (de) 1987-12-03 1988-12-02 9-(Acylamino)tetrahydroacridinderivate und wahrnehmungssteigernde Mittel davon als aktiver Wirkstoff.
AT8888403058T ATE104966T1 (de) 1987-12-03 1988-12-02 9-(acylamino)tetrahydroacridinderivate und wahrnehmungssteigernde mittel davon als aktiver wirkstoff.
EP88403058A EP0319429B1 (en) 1987-12-03 1988-12-02 9-Acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient
KR1019880016146A KR0128975B1 (ko) 1987-12-03 1988-12-03 9-아실아미노-테트라히드로아크리딘 유도체 및 그 유도체를 활성 성분으로 포함하는 기억력 촉진제

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP62-306753 1987-12-03
JP30675387 1987-12-03
JP63283351A JPH01250353A (ja) 1987-12-03 1988-11-09 ９−アシルアミノ−テトラヒドロアクリジン誘導体及び該誘導体を有効成分とする記憶障害改善剤

Publications (1)

Publication Number Publication Date
JPH01250353A true JPH01250353A (ja) 1989-10-05

Family

ID=26555006

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63283351A Pending JPH01250353A (ja) 1987-12-03 1988-11-09 ９−アシルアミノ−テトラヒドロアクリジン誘導体及び該誘導体を有効成分とする記憶障害改善剤

Country Status (3)

Country Link
JP (1) JPH01250353A (ko)
KR (1) KR0128975B1 (ko)
HU (1) HU202499B (ko)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03151366A (ja) * 1989-11-08 1991-06-27 Mitsubishi Kasei Corp ９―アミノアセチルアミノテトラヒドロアクリジン誘導体
JPH03218361A (ja) * 1989-11-08 1991-09-25 Mitsubishi Kasei Corp ９―アシルアミノテトラヒドロアクリジン誘導体
JP2013523607A (ja) * 2010-03-26 2013-06-17 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング オートタキシン阻害剤としてのベンゾナフチリジンアミン

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03151366A (ja) * 1989-11-08 1991-06-27 Mitsubishi Kasei Corp ９―アミノアセチルアミノテトラヒドロアクリジン誘導体
JPH03218361A (ja) * 1989-11-08 1991-09-25 Mitsubishi Kasei Corp ９―アシルアミノテトラヒドロアクリジン誘導体
JP2013523607A (ja) * 2010-03-26 2013-06-17 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング オートタキシン阻害剤としてのベンゾナフチリジンアミン
US9029387B2 (en) 2010-03-26 2015-05-12 Merck Patent Gmbh Benzonaphthyridinamines as autotaxin inhibitors

Also Published As

Publication number Publication date
KR0128975B1 (ko) 1998-04-09
KR890009876A (ko) 1989-08-04
HUT50460A (en) 1990-02-28
HU202499B (en) 1991-03-28

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