JP7426431B2 - 用量設定機構及び注射装置 - Google Patents
用量設定機構及び注射装置 Download PDFInfo
- Publication number
- JP7426431B2 JP7426431B2 JP2022068726A JP2022068726A JP7426431B2 JP 7426431 B2 JP7426431 B2 JP 7426431B2 JP 2022068726 A JP2022068726 A JP 2022068726A JP 2022068726 A JP2022068726 A JP 2022068726A JP 7426431 B2 JP7426431 B2 JP 7426431B2
- Authority
- JP
- Japan
- Prior art keywords
- dose
- knob
- snap element
- selector
- setting mechanism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000007246 mechanism Effects 0.000 title claims description 97
- 238000002347 injection Methods 0.000 title claims description 84
- 239000007924 injection Substances 0.000 title claims description 84
- 230000008878 coupling Effects 0.000 claims description 69
- 238000010168 coupling process Methods 0.000 claims description 69
- 238000005859 coupling reaction Methods 0.000 claims description 69
- 239000003814 drug Substances 0.000 claims description 43
- 238000000034 method Methods 0.000 claims description 39
- 230000003993 interaction Effects 0.000 claims description 4
- 238000004448 titration Methods 0.000 claims description 4
- 238000007667 floating Methods 0.000 description 36
- 229940079593 drug Drugs 0.000 description 34
- 230000037452 priming Effects 0.000 description 34
- 238000013461 design Methods 0.000 description 23
- 238000004519 manufacturing process Methods 0.000 description 16
- 230000000903 blocking effect Effects 0.000 description 13
- 238000012377 drug delivery Methods 0.000 description 10
- 230000002441 reversible effect Effects 0.000 description 9
- 230000006870 function Effects 0.000 description 8
- 230000008901 benefit Effects 0.000 description 5
- 230000000712 assembly Effects 0.000 description 4
- 238000000429 assembly Methods 0.000 description 4
- 230000000977 initiatory effect Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 230000006835 compression Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 239000012530 fluid Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000013011 mating Effects 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 238000007639 printing Methods 0.000 description 2
- 238000005096 rolling process Methods 0.000 description 2
- 238000013519 translation Methods 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 208000010415 Low Vision Diseases 0.000 description 1
- 206010057362 Underdose Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 229940090048 pen injector Drugs 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31536—Blocking means to immobilize a selected dose, e.g. to administer equal doses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31556—Accuracy improving means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31563—Mechanically operated dose setting member interacting with a displaceable stop member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/3157—Means providing feedback signals when administration is completed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31536—Blocking means to immobilize a selected dose, e.g. to administer equal doses
- A61M2005/3154—Blocking means to immobilize a selected dose, e.g. to administer equal doses limiting maximum permissible dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
2 カートリッジホルダ
3 ハウジング
3a 窓
3b 長手方向スプライン
3d 内面
4 ペンニードル
5 ハブ
6 両頭針カニューレ
7 ニードルコネクタ
8 カートリッジ
8a セプタム
9 ピストン
10 注射装置
30 用量設定機構
31 用量ノブ
31a ノブスプライン
31c スナップフィット
33 スナップ要素
33a 外面
34 フローティングスプラインアセンブリ
35 用量セレクタ
35a 長手方向溝
35b 内面
38 用量スリーブ
42 ピストンロッド
42a 脚部
44 スプライン
45 突起部
45a 柔軟アーム
48 内部スプライン
48a スナップ要素
52 長手方向スプライン
54 固定用量セレクタスプライン
55 用量停止部
55a プライミング停止部
55b 注入バンプ
55c 最大用量ハードストップ
55d ゼロ用量ハードストップ
55e 傾斜面
56 周方向リブ
56a カットアウト
59 接続カットアウト
Claims (15)
- 用量ノブ(31)、
1又は複数の所定の固定用量設定の有限のセットに対応する1又は複数の用量停止部(55)を有する用量セレクタ(35)、及び
スナップ要素(33)、を有し、
設定用量の送達が、前記用量ノブ(31)に近位方向に適用される軸方向駆動力を必要とし、
前記用量ノブ(31)と前記用量セレクタ(35)は、用量送達手順の開始時に前記スナップ要素(33)に対して近位方向に軸方向に移動するように構成されており、
前記用量セレクタ(35)は、半径方向に突出する周方向リブ(56)を有し、前記スナップ要素(33)は突起部(46)を有し、
前記半径方向に突出するリブ(56)は、1又は複数のカットアウト(56a)を有し、
前記用量セレクタ(35)は近位方向に押されて移動できるだけであり、前記突起部(46)が前記半径方向に突出するリブ(56)の前記カットアウト(56a)の1つと整列した時に用量送達が開始され、前記半径方向に突出するリブ(56)が前記突起部(46)を過ぎて軸方向に移動されて用量送達が開始され、
前記突起部(46)が前記半径方向に突出するリブ(56)の前記カットアウト(56a)の1つと整列しない時に、前記突起部(46)は前記半径方向に突出するリブ(56)と係合するように構成されている、用量設定機構(30)。 - 前記半径方向に突出するリブ(56)は、前記用量セレクタ(35)の内面(35b)に位置する、請求項1に記載の用量設定機構(30)。
- 1又は複数の前記カットアウト(56a)は、前記用量停止部(55)のそれぞれに対応する、請求項1又は2に記載の用量設定機構(30)。
- 前記用量セレクタ(35)の軸方向移動が、前記半径方向に突出するリブ(56)を、前記突起部(46)が前記半径方向に突出するリブ(56)の近位対向側に位置する第1位置から、前記突起部(46)が前記半径方向に突出するリブ(56)の遠位対向側に位置決めされる第2位置へ移動させる、請求項1~3のいずれか一項に記載の用量設定機構(30)。
- 前記スナップ要素(33)が、用量設定中及び用量送達中に前記用量セレクタ(35)に対して回転するように構成されている、請求項1~4のいずれか一項に記載の用量設定機構(30)。
- 前記用量ノブ(31)の近位軸方向移動は、スプライン(31a)などの前記用量ノブ(31)上の結合要素を、固定スプライン(44)などの前記スナップ要素(33)上の結合要素から外させる、請求項1~5のいずれか一項に記載の用量設定機構(30)。
- 用量設定中の前記スナップ要素(33)の回転はまた、用量設定機構(30)のピストンロッド(42)と係合したナットの回転を生じさせ、
前記ピストンロッド(42)に対する前記ナット(36)の位置が送達すべき薬剤の量に正比例する、請求項1~6のいずれか一項に記載の用量設定機構(30)。 - 前記1又は複数の所定の固定用量の設定は、前記スナップ要素(33)と前記用量セレクタ(35)の相互作用により達成される、請求項1~7のいずれか一項に記載の用量設定機構(30)。
- 前記用量ノブ(31)は用量設定中にユーザによって回転されるように構成されている、請求項1~8のいずれか一項に記載の用量設定機構(30)。
- 用量設定中の前記用量ノブ(31)の回転が、前記スナップ要素(33)の回転及び軸方向移動を生じさせ、また前記用量セレクタ(35)の軸方向移動のみを生じさせる、請求項9に記載の用量設定機構(30)。
- 前記1又は複数の用量停止部(55)は、前記用量セレクタ(35)の内面(35b)に周方向に位置決めされ、
それぞれの用量停止部(55)とゼロ用量ハードストップ(55d)の間の周方向距離はそれぞれの固定用量に正比例する、請求項1~10のいずれか一項に記載の用量設定機構(30)。 - 結合アセンブリ(34)が、前記スナップ要素(33)と回転方向に係合し、
前記結合アセンブリ(34)が、用量設定中及び用量送達中に前記用量セレクタ(35)における複数の用量セレクタ結合要素の対応するセットと係合し、
前記スナップ要素(33)が、複数のスナップ結合要素(44)の固定セットを有し、
前記用量ノブ(31)における複数のノブ結合要素(31a)が、用量設定中に前記スナップ要素(33)の前記複数のスナップ結合要素(44)の固定セットと係合し、噛み合うが、用量設定中には係合せず、
前記結合アセンブリ(34)が、互いから等しく離れた、多数の半径方向に突出する長手方向スプライン(52)を有し、
前記結合アセンブリ(34)が、用量送達中に前記半径方向に突出する長手方向スプライン(52)を介して前記用量ノブ(31)における前記複数のノブ結合要素(31a)と係合するが、用量設定中には係合しない、請求項1~11のいずれか一項に記載の用量設定機構(30)。 - 前記用量停止部(55)のそれぞれの間の空間は、前記半径方向に突出する長手方向スプライン(52)のそれぞれの間の空間の倍数である、請求項12に記載の用量設定機構(30)。
- 前記結合アセンブリ(34)が前記スナップ要素(33)に対して軸方向に固定されている、請求項12又は13に記載の用量設定機構(30)。
- 請求項1~14のいずれか一項に記載の用量設定機構(30)を有する注射装置。
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/649,287 | 2017-07-13 | ||
US15/649,287 US10688247B2 (en) | 2017-07-13 | 2017-07-13 | Injection device with flexible dose selection |
JP2020501134A JP7113068B2 (ja) | 2017-07-13 | 2017-09-25 | 柔軟な用量選択を有する用量設定機構及び注射装置 |
PCT/EP2017/001140 WO2019011394A1 (en) | 2017-07-13 | 2017-09-25 | INJECTION DEVICE WITH CHOICE OF FLEXIBLE DOSE |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020501134A Division JP7113068B2 (ja) | 2017-07-13 | 2017-09-25 | 柔軟な用量選択を有する用量設定機構及び注射装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2022095937A JP2022095937A (ja) | 2022-06-28 |
JP7426431B2 true JP7426431B2 (ja) | 2024-02-01 |
Family
ID=59966694
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020501134A Active JP7113068B2 (ja) | 2017-07-13 | 2017-09-25 | 柔軟な用量選択を有する用量設定機構及び注射装置 |
JP2022068725A Pending JP2022095936A (ja) | 2017-07-13 | 2022-04-19 | 用量設定機構及び注射装置 |
JP2022068723A Active JP7426429B2 (ja) | 2017-07-13 | 2022-04-19 | プライミング特徴を有する注射装置及び注射装置のプライミング手順を実行する方法 |
JP2022068724A Active JP7426430B2 (ja) | 2017-07-13 | 2022-04-19 | 用量設定機構及び注射装置 |
JP2022068727A Pending JP2022095938A (ja) | 2017-07-13 | 2022-04-19 | 用量設定機構及び注射装置 |
JP2022068728A Pending JP2022095939A (ja) | 2017-07-13 | 2022-04-19 | 用量設定機構及び注射装置 |
JP2022068726A Active JP7426431B2 (ja) | 2017-07-13 | 2022-04-19 | 用量設定機構及び注射装置 |
Family Applications Before (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020501134A Active JP7113068B2 (ja) | 2017-07-13 | 2017-09-25 | 柔軟な用量選択を有する用量設定機構及び注射装置 |
JP2022068725A Pending JP2022095936A (ja) | 2017-07-13 | 2022-04-19 | 用量設定機構及び注射装置 |
JP2022068723A Active JP7426429B2 (ja) | 2017-07-13 | 2022-04-19 | プライミング特徴を有する注射装置及び注射装置のプライミング手順を実行する方法 |
JP2022068724A Active JP7426430B2 (ja) | 2017-07-13 | 2022-04-19 | 用量設定機構及び注射装置 |
JP2022068727A Pending JP2022095938A (ja) | 2017-07-13 | 2022-04-19 | 用量設定機構及び注射装置 |
JP2022068728A Pending JP2022095939A (ja) | 2017-07-13 | 2022-04-19 | 用量設定機構及び注射装置 |
Country Status (7)
Country | Link |
---|---|
US (6) | US10688247B2 (ja) |
EP (11) | EP3651837B1 (ja) |
JP (7) | JP7113068B2 (ja) |
CN (7) | CN114712630A (ja) |
CA (1) | CA3069583A1 (ja) |
DK (1) | DK3651837T3 (ja) |
WO (1) | WO2019011394A1 (ja) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11484654B2 (en) | 2017-06-30 | 2022-11-01 | Regeneron Pharmaceuticals, Inc. | Auto-injector with anti-roll features |
US10688247B2 (en) | 2017-07-13 | 2020-06-23 | Haselmeier Ag | Injection device with flexible dose selection |
JP1631348S (ja) * | 2017-11-06 | 2019-05-13 | ||
US11969583B2 (en) * | 2018-07-17 | 2024-04-30 | Medmix Switzerland Ag | Injection device with dose interruption fail safe |
CN113613694B (zh) * | 2019-02-19 | 2024-04-30 | 迈德米斯瑞士股份公司 | 具有用户友好的剂量选择器的注射装置 |
JP7422165B2 (ja) | 2019-04-11 | 2024-01-25 | メドミクス スウィッツァランド アーゲー | 滑り防止機能を備える用量送達機構 |
JP1691373S (ja) * | 2019-11-01 | 2021-08-02 | ||
EP4070829A1 (en) | 2021-04-07 | 2022-10-12 | medmix Switzerland AG | Drug delivery device with balancing weight |
EP4319844A1 (en) | 2021-04-07 | 2024-02-14 | medmix Switzerland AG | Drug delivery device |
EP4070832A1 (en) | 2021-04-07 | 2022-10-12 | medmix Switzerland AG | Keyed connectors |
EP4085946A1 (en) | 2021-05-03 | 2022-11-09 | medmix Switzerland AG | Method for identifying a drug delivery device, set of a drug delivery device and an electronic device for identifying a drug delivery device |
EP4306148A1 (en) * | 2022-07-12 | 2024-01-17 | medmix Switzerland AG | Dose setting mechanism and method of locking an injection pen |
US20240058540A1 (en) * | 2022-04-27 | 2024-02-22 | Medmix Switzerland Ag | Cartridge holding unit |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002503116A (ja) | 1995-03-07 | 2002-01-29 | イーライ・リリー・アンド・カンパニー | 再利用可能な投薬装置 |
JP2012507314A (ja) | 2008-11-06 | 2012-03-29 | ノボ・ノルデイスク・エー/エス | 電子的に支援された薬剤送達装置 |
WO2016128424A1 (en) | 2015-02-10 | 2016-08-18 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for an injection device |
Family Cites Families (115)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4973318A (en) | 1988-02-10 | 1990-11-27 | D.C.P. Af 1988 A/S | Disposable syringe |
JPH06503292A (ja) | 1990-12-14 | 1994-04-14 | ヘイブリー メディカル テクノロジー コーポレイション | 可変混合比ディスペンサー |
JP4399752B2 (ja) | 1999-07-06 | 2010-01-20 | 日本ケミカルリサーチ株式会社 | 薬剤溶解機構内蔵注射器 |
US6277099B1 (en) | 1999-08-06 | 2001-08-21 | Becton, Dickinson And Company | Medication delivery pen |
TW453884B (en) * | 1999-09-16 | 2001-09-11 | Novo Nordisk As | Dose setting limiter |
AU7839900A (en) | 1999-09-29 | 2001-04-30 | Sterling Medivations, Inc. | Reusable medication delivery device |
US6899699B2 (en) | 2001-01-05 | 2005-05-31 | Novo Nordisk A/S | Automatic injection device with reset feature |
US7654986B2 (en) | 2002-07-03 | 2010-02-02 | Novo Nordisk A/S | Needle mounting system and a method for mounting a needle assembly |
GB0304822D0 (en) * | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
US6932794B2 (en) * | 2003-04-03 | 2005-08-23 | Becton, Dickinson And Company | Medication delivery pen |
EP1656170B1 (en) * | 2003-08-12 | 2019-03-13 | Eli Lilly And Company | Medication dispensing apparatus with triple screw threads for mechanical advantage |
DE20317377U1 (de) | 2003-11-03 | 2005-03-17 | B D Medico S A R L | Injektionsgerät |
GB2410190A (en) | 2004-01-26 | 2005-07-27 | Medical House Plc | Disposable gas-powered needle-free injection device |
DE102004004310A1 (de) * | 2004-01-28 | 2005-08-18 | Tecpharma Licensing Ag | Injektionsgerät mit verrastbarem Dosierglied |
DE102004020374A1 (de) * | 2004-04-23 | 2005-11-10 | Tecpharma Licensing Ag | Vorrichtung zur Verabreichung eines injizierbaren Produkts mit gesicherter Dosiereinrichtung |
ATE445429T1 (de) | 2004-10-21 | 2009-10-15 | Novo Nordisk As | Injektionsvorrichtung mit internem dosisanzeiger |
WO2006045526A1 (en) | 2004-10-21 | 2006-05-04 | Novo Nordisk A/S | Dial-down mechanism for wind-up pen |
JP5175556B2 (ja) * | 2005-02-28 | 2013-04-03 | ノボ・ノルデイスク・エー/エス | 最大投与量の事前設定が可能な、注入デバイスのための投与量設定機構 |
DE102005023824A1 (de) * | 2005-05-24 | 2006-12-07 | Tecpharma Licensing Ag | Dosiervorrichtung für eine Injektionsvorrichtung |
ATE499962T1 (de) * | 2005-07-27 | 2011-03-15 | Novo Nordisk As | Dosismechanismus für ein injektionsgerät zur begrenzung einer dosiseinstellung entsprechend der verbleibenden arzneimenge |
DE102006004561A1 (de) | 2006-01-17 | 2007-07-26 | Tecpharma Licensing Ag | Injektionsvorrichtung mit gesichertem Drehknopf |
BRPI0713802A2 (pt) | 2006-06-30 | 2012-11-06 | Abbott Biotech Ltd | dispositivo de injeção automático |
CN101563123B (zh) | 2006-09-15 | 2012-08-29 | 特克法马许可公司 | 带有改进的输送元件的注射仪器 |
ES2351778T5 (es) | 2007-02-05 | 2019-07-09 | Novo Nordisk As | Botón de inyección |
WO2008116766A1 (en) * | 2007-03-23 | 2008-10-02 | Novo Nordisk A/S | An injection device comprising a locking nut |
WO2009014955A2 (en) | 2007-07-20 | 2009-01-29 | Amylin Pharmaceuticals, Inc. | Pen injection device and method of using same |
EP2244768B1 (en) * | 2008-01-23 | 2019-04-03 | Novo Nordisk A/S | Device for injecting apportioned doses of liquid drug |
US8992484B2 (en) | 2008-01-23 | 2015-03-31 | Novo Nordisk A/S | Device for injecting apportioned doses of liquid drug |
WO2009098299A1 (en) * | 2008-02-07 | 2009-08-13 | Novo Nordisk A/S | Injection device having mode defining elements |
WO2009114542A1 (en) | 2008-03-10 | 2009-09-17 | Antares Pharma, Inc. | Injector safety device |
WO2010081489A1 (de) | 2009-01-15 | 2010-07-22 | Tecpharma Licensing Ag | Vorrichtung zur verabreichung eines injizierbaren produkts |
CN102413854B (zh) | 2009-02-26 | 2013-08-28 | Shl集团有限责任公司 | 剂量设定机构 |
CA2756937A1 (en) | 2009-03-31 | 2010-10-07 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
EP2266647A1 (en) * | 2009-06-25 | 2010-12-29 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for drug delivery device |
US20120283659A1 (en) * | 2009-09-30 | 2012-11-08 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device |
AR078459A1 (es) * | 2009-09-30 | 2011-11-09 | Sanofi Aventis Deutschland | Conjunto de accionamiento, vastago de piston, dispositivo para la entrega de drogas, y uso de un resorte |
CA2773928A1 (en) * | 2009-09-30 | 2011-04-07 | Sanofi-Aventis Deutschland Gmbh | Injection device |
EP2485787A1 (en) | 2009-10-08 | 2012-08-15 | Sanofi-Aventis Deutschland GmbH | Medicament injection device with lockout feature |
EP2501421B1 (en) | 2009-11-20 | 2019-08-21 | Becton Dickinson and Company | Injection device without a gearing |
DK2506890T3 (da) * | 2009-12-01 | 2020-09-21 | Becton Dickinson Co | Injektionspen med tilbagetræknings- og sidste-dosis-styring |
US9795744B2 (en) * | 2009-12-15 | 2017-10-24 | Shl Group Ab | Medicament delivery device |
US11957885B2 (en) | 2010-02-09 | 2024-04-16 | Shl Medical Ag | Medicament delivery device |
JP5795775B2 (ja) * | 2010-02-17 | 2015-10-14 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 注射デバイス |
EP3196212B1 (en) | 2010-02-24 | 2020-06-03 | ImmunoGen, Inc. | Immunoconjugates comprising a folate receptor 1 antibody |
BR112013008905A2 (pt) * | 2010-10-13 | 2017-07-11 | Sanofi Aventis Deutschland | mecanismo de dosagem e método de dosagem |
EP2452711A1 (en) * | 2010-11-12 | 2012-05-16 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for a drug delivery device and drug delivery device |
JP5732549B2 (ja) | 2011-02-03 | 2015-06-10 | エス・ホー・エル・グループ・アクチボラゲットShl Group Ab | 薬剤送達装置 |
US11577029B2 (en) | 2012-03-15 | 2023-02-14 | Becton, Dickinson And Company | Multiple use disposable injection pen |
TWI595904B (zh) | 2011-03-25 | 2017-08-21 | 賽諾菲阿凡提斯德意志有限公司 | 劑量設定機構及注射裝置 |
SG193285A1 (en) | 2011-03-25 | 2013-10-30 | Sanofi Aventis Deutschland | Dose setting mechanism and injection device |
DE102011107199A1 (de) | 2011-07-13 | 2013-01-17 | Haselmeier Gmbh | Injektionsgerät und Verfahren zu dessen Herstellung |
CN103781505B (zh) | 2011-09-06 | 2016-06-01 | 诺沃—诺迪斯克有限公司 | 活塞杆座 |
CN104010677B (zh) * | 2011-10-17 | 2016-08-24 | Shl集团有限责任公司 | 药物输送装置 |
DE202012001410U1 (de) | 2012-02-10 | 2013-05-13 | Haselmeier Gmbh | Injektionsgerät |
DE202012001411U1 (de) | 2012-02-10 | 2013-05-13 | Haselmeier Gmbh | Injektionsgerät |
WO2013120776A1 (en) * | 2012-02-13 | 2013-08-22 | Sanofi-Aventis Deutschland Gmbh | Supplemental device for attachment to an injection device |
EP2644218B2 (de) * | 2012-03-30 | 2022-11-02 | Tecpharma Licensing AG | Injektionsvorrichtung mit Dosisanzeige und Federantrieb |
JP6197027B2 (ja) | 2012-04-20 | 2017-09-13 | ノボ・ノルデイスク・エー/エス | 2次安全リミッターを備える医療用注射デバイス |
CN104363939B (zh) * | 2012-05-31 | 2017-09-12 | 诺和诺德股份有限公司 | 用于装有发条的笔的拨动降低机构 |
EP2869873B1 (en) | 2012-07-06 | 2018-07-18 | Carebay Europe Ltd. | Medicament delivery device |
EP2885027B1 (en) | 2012-08-20 | 2017-08-09 | Novo Nordisk A/S | A spring-loaded injection device with an injection button |
DE202013001350U1 (de) | 2013-02-08 | 2014-05-09 | Haselmeier Gmbh | Injektionsgerät |
EP2968784B1 (en) | 2013-03-13 | 2021-11-24 | Sanofi-Aventis Deutschland GmbH | Assembly for a drug delivery device comprising a feedback feature |
JP6429809B2 (ja) * | 2013-03-13 | 2018-11-28 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 薬物送達デバイス、および薬物送達デバイス用のピストンロッドのクリアランスを除くための方法 |
WO2014166922A2 (en) | 2013-04-10 | 2014-10-16 | Sanofi | Injection device |
JP6419158B2 (ja) | 2013-04-10 | 2018-11-07 | サノフイSanofi | 薬物送達デバイスの駆動機構 |
WO2014166910A1 (en) * | 2013-04-10 | 2014-10-16 | Sanofi | Injection device |
JP6433484B2 (ja) | 2013-04-10 | 2018-12-05 | サノフイSanofi | 薬物送達デバイスの駆動機構 |
AU2014253444B2 (en) | 2013-04-12 | 2016-12-15 | Carebay Europe Ltd | Medicament delivery device |
EP3003434B1 (en) | 2013-06-04 | 2019-03-13 | Novo Nordisk A/S | Torsion spring injection device having an end-of-dose mechanism |
CN105377342B (zh) * | 2013-07-17 | 2019-10-22 | 赛诺菲 | 药物输送装置 |
JP2016524974A (ja) | 2013-07-17 | 2016-08-22 | サノフイ | 標示アセンブリ |
JP6426171B2 (ja) | 2013-07-17 | 2018-11-21 | サノフイSanofi | 薬物送達デバイス |
DK3021911T3 (da) | 2013-07-17 | 2021-10-11 | Sanofi Sa | Anordning til indgivelse af lægemidler |
WO2015007823A1 (en) | 2013-07-17 | 2015-01-22 | Sanofi | Drug delivery device |
EP2829292B1 (de) * | 2013-07-22 | 2017-11-01 | TecPharma Licensing AG | Antriebs- und Dosiervorrichtung mit einem Begrenzungselement zur Verhinderung der Einstellung einer höheren Dosis als verfügbar |
TW201521819A (zh) | 2013-09-03 | 2015-06-16 | Sanofi Sa | 用於藥物輸送裝置的機構以及包含該機構的藥物輸送裝置 |
JP2016530045A (ja) * | 2013-09-16 | 2016-09-29 | ノボ・ノルデイスク・エー/エス | 選択的な定量投与または可変量投与のための注射装置 |
WO2015055640A1 (en) * | 2013-10-16 | 2015-04-23 | Novo Nordisk A/S | Drug delivery device with improved dose reset mechanism |
GB201318817D0 (en) | 2013-10-24 | 2013-12-11 | Owen Mumford Ltd | Injection Devices |
EP3068466A1 (en) | 2013-11-12 | 2016-09-21 | Novo Nordisk A/S | Drug delivery device with movable needle mount |
EP3071270B1 (en) | 2013-11-22 | 2024-01-17 | Sanofi-Aventis Deutschland GmbH | Drug delivery device with dose knob clutch |
WO2015090320A2 (en) | 2013-12-18 | 2015-06-25 | Cpu Innovation | Dose delivery device with improved handling |
EP3089777A1 (en) * | 2014-01-03 | 2016-11-09 | Novo Nordisk A/S | Auto-injection device with button activation |
DE202014001134U1 (de) | 2014-02-05 | 2015-05-06 | Haselmeier Gmbh | Injektionsgerät |
DE202014001136U1 (de) | 2014-02-05 | 2015-05-06 | Haselmeier Gmbh | Injektionsgerät |
DE202014001135U1 (de) | 2014-02-05 | 2015-05-06 | Haselmeier Gmbh | Injektionsgerät |
AU2015237887B2 (en) * | 2014-03-25 | 2018-10-04 | Wockhardt Limited | Fluid delivery pen with final dose stop and improved dose setting features |
TW201603847A (zh) * | 2014-07-01 | 2016-02-01 | 賽諾菲公司 | 注射裝置及組裝方法 |
US9925335B2 (en) | 2014-08-18 | 2018-03-27 | Windgap Medical, Inc | Portable drug mixing and delivery device and associated methods |
US10569026B2 (en) | 2014-10-09 | 2020-02-25 | Sanofi | Resettable drug delivery device |
CN106794307B (zh) * | 2014-10-09 | 2020-09-25 | 赛诺菲 | 具有在更换药筒时允许活塞杆缩回的复位机构的药物注射装置 |
DK3223888T3 (da) | 2014-11-24 | 2023-10-02 | Sanofi Sa | Dosisindstillingsmekanisme og lægemiddeladministrationsanordning med skraldemekanisme |
EP3268066A1 (en) | 2015-03-12 | 2018-01-17 | Sanofi | Drug delivery device |
WO2016188983A1 (en) | 2015-05-27 | 2016-12-01 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
US20180147364A1 (en) | 2015-05-28 | 2018-05-31 | Novo Nordisk A/S | Drug Delivery Device with Multifunctional Bias Structure |
WO2016198540A2 (en) | 2015-06-11 | 2016-12-15 | Novo Nordisk A/S | Drug delivery device with extended protective cap |
WO2017001692A1 (en) * | 2015-07-01 | 2017-01-05 | Novo Nordisk A/S | Drug delivery device with priming mechanism |
GB2541227A (en) | 2015-08-13 | 2017-02-15 | Owen Mumford Ltd | Injector Device |
WO2017055492A1 (en) | 2015-10-01 | 2017-04-06 | Novo Nordisk A/S | Torsion spring fixation in automatic drug delivery device |
EP3162397B1 (en) * | 2015-10-29 | 2019-07-31 | TecPharma Licensing AG | Dose setting mechanism for an injection device having a dose limiter |
FR3043562B1 (fr) * | 2015-11-13 | 2022-01-21 | Aptar France Sas | Autoinjecteur. |
EP3181169A1 (en) * | 2015-12-14 | 2017-06-21 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for an injection device |
EP3181170A1 (en) | 2015-12-14 | 2017-06-21 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for an injection device |
EP3181171A1 (en) | 2015-12-14 | 2017-06-21 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for an injection device |
CN206045102U (zh) * | 2016-07-21 | 2017-03-29 | 翁建森 | 一种具有安全保护机构可调节剂量的自动注射装置 |
GB201615447D0 (en) | 2016-09-12 | 2016-10-26 | Norton Healthcare Ltd | Dose delivery mechanism |
EP3576820A1 (en) | 2017-02-03 | 2019-12-11 | Norton Healthcare Limited | Assembly for a medication delivery device and medication delivery device |
JP7033611B2 (ja) | 2017-05-11 | 2022-03-10 | ノボ・ノルデイスク・エー/エス | ピストンロッドブレーキ機構 |
US10688247B2 (en) | 2017-07-13 | 2020-06-23 | Haselmeier Ag | Injection device with flexible dose selection |
WO2019162222A1 (en) | 2018-02-26 | 2019-08-29 | Haselmeier Ag | Dosage determination using electrical conductivity in an injection device |
EP4062958A1 (en) | 2018-04-13 | 2022-09-28 | medmix Switzerland AG | Medicament delivery device |
US11969583B2 (en) * | 2018-07-17 | 2024-04-30 | Medmix Switzerland Ag | Injection device with dose interruption fail safe |
CN113613694B (zh) | 2019-02-19 | 2024-04-30 | 迈德米斯瑞士股份公司 | 具有用户友好的剂量选择器的注射装置 |
WO2021214272A1 (en) | 2020-04-23 | 2021-10-28 | Sanofi | Mechanism unit for a drug delivery device and drug delivery device |
-
2017
- 2017-07-13 US US15/649,287 patent/US10688247B2/en active Active
- 2017-09-25 EP EP17772308.7A patent/EP3651837B1/en active Active
- 2017-09-25 EP EP22192212.3A patent/EP4112105A1/en not_active Withdrawn
- 2017-09-25 CN CN202210184869.0A patent/CN114712630A/zh active Pending
- 2017-09-25 CN CN202210184868.6A patent/CN114712629A/zh active Pending
- 2017-09-25 EP EP21168744.7A patent/EP3871715A1/en active Pending
- 2017-09-25 DK DK17772308.7T patent/DK3651837T3/da active
- 2017-09-25 EP EP21168811.4A patent/EP3868422A1/en active Pending
- 2017-09-25 EP EP21168911.2A patent/EP3868425A1/en active Pending
- 2017-09-25 EP EP22172125.1A patent/EP4059549A1/en active Pending
- 2017-09-25 CA CA3069583A patent/CA3069583A1/en active Pending
- 2017-09-25 JP JP2020501134A patent/JP7113068B2/ja active Active
- 2017-09-25 CN CN202210184867.1A patent/CN114712628B/zh active Active
- 2017-09-25 EP EP22192125.7A patent/EP4112104A1/en active Pending
- 2017-09-25 EP EP21168901.3A patent/EP3868424A1/en active Pending
- 2017-09-25 CN CN202210184866.7A patent/CN114712627A/zh active Pending
- 2017-09-25 EP EP21168770.2A patent/EP3871716A1/en active Pending
- 2017-09-25 WO PCT/EP2017/001140 patent/WO2019011394A1/en unknown
- 2017-09-25 EP EP22171816.6A patent/EP4056216A1/en active Pending
- 2017-09-25 CN CN202210184864.8A patent/CN114712626A/zh active Pending
- 2017-09-25 CN CN201780093080.1A patent/CN110997041B/zh active Active
- 2017-09-25 CN CN202210184863.3A patent/CN114712625A/zh active Pending
- 2017-09-25 EP EP21168836.1A patent/EP3868423A1/en active Pending
-
2020
- 2020-05-14 US US16/874,386 patent/US20200268977A1/en not_active Abandoned
- 2020-05-29 US US16/888,127 patent/US20200289763A1/en not_active Abandoned
- 2020-05-29 US US16/888,086 patent/US11969584B2/en active Active
-
2022
- 2022-04-19 JP JP2022068725A patent/JP2022095936A/ja active Pending
- 2022-04-19 JP JP2022068723A patent/JP7426429B2/ja active Active
- 2022-04-19 JP JP2022068724A patent/JP7426430B2/ja active Active
- 2022-04-19 JP JP2022068727A patent/JP2022095938A/ja active Pending
- 2022-04-19 JP JP2022068728A patent/JP2022095939A/ja active Pending
- 2022-04-19 JP JP2022068726A patent/JP7426431B2/ja active Active
-
2023
- 2023-06-05 US US18/205,966 patent/US20230302228A1/en active Pending
- 2023-06-05 US US18/205,957 patent/US20230321357A1/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002503116A (ja) | 1995-03-07 | 2002-01-29 | イーライ・リリー・アンド・カンパニー | 再利用可能な投薬装置 |
JP2012507314A (ja) | 2008-11-06 | 2012-03-29 | ノボ・ノルデイスク・エー/エス | 電子的に支援された薬剤送達装置 |
WO2016128424A1 (en) | 2015-02-10 | 2016-08-18 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for an injection device |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP7426431B2 (ja) | 用量設定機構及び注射装置 | |
RU2676032C1 (ru) | Одноразовая шприц-ручка на несколько доз | |
JP7228036B2 (ja) | 用量中断フェイル・セーフを備えた注射デバイス | |
US20220118192A1 (en) | Injection device with user friendly dose selector |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220517 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20220517 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20230331 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20230404 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20230703 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20230901 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20231003 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20240116 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20240122 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 7426431 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |