JP7277413B2 - 成型フレームを有する生物学的流体フィルタとそのフィルタの作製方法 - Google Patents
成型フレームを有する生物学的流体フィルタとそのフィルタの作製方法 Download PDFInfo
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- JP7277413B2 JP7277413B2 JP2020077189A JP2020077189A JP7277413B2 JP 7277413 B2 JP7277413 B2 JP 7277413B2 JP 2020077189 A JP2020077189 A JP 2020077189A JP 2020077189 A JP2020077189 A JP 2020077189A JP 7277413 B2 JP7277413 B2 JP 7277413B2
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- housing wall
- filter assembly
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- flexible housing
- biological fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
- A61M1/3635—Constructional details
- A61M1/3636—Constructional details having a flexible housing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids
- A61M2005/1655—Filter with fibers, e.g. filtering element in form of hollow fibers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0439—White blood cells; Leucocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
- Filtering Materials (AREA)
- Filtering Of Dispersed Particles In Gases (AREA)
Description
本願は、2014年3月24日に出願され、ここに内容が参照として組み込まれる米国特許出願番号第14/223,831号に基づく優先権と利益とを主張する。
Claims (16)
- 生物学的流体フィルタアセンブリであって、
a)縁と、内表面と外表面と入口側と出口側とを備える、1個の一体的に成型されたフレームであって、前記縁は、前記フレームの中央に中央開口を規定する、フレームと;
b)複数の積層されたシートを備えるろ過媒体と;
c)前記フィルタアセンブリのほぼ反対の端部に配置された、少なくとも1つの入口ポートと1つの出口ポートと;そして
d)前記フレームの前記入口側において前記フレームの前記内表面と前記ろ過媒体の間にある第1の可撓性ハウジング壁と前記フレームの前記出口側において前記フレームの前記内表面と前記ろ過媒体の間にある第2の可撓性ハウジング壁
とを備え、
前記第1の可撓性ハウジング壁と前記第2の可撓性ハウジング壁は、それぞれ外表面を有し、
前記少なくとも1つの入口ポートと1つの出口ポートは、前記第1の可撓性ハウジング壁と前記第2の可撓性ハウジング壁の前記外表面上に有され、
前記ろ過媒体と前記第1の可撓性ハウジング壁と前記第2の可撓性ハウジング壁は前記フレーム内に含まれ捉えられるようにインサート成型されており、
e)前記第1の可撓性ハウジング壁と前記第2の可撓性ハウジング壁の間には直接のシールがない、生物学的流体フィルタアセンブリ。 - 前記ろ過媒体は前記出口側において前記第2の可撓性ハウジング壁の前記内表面から離間されている、請求項1に記載の生物学的流体フィルタアセンブリ。
- 前記可撓性ハウジング壁と前記ろ過媒体との間には直接のシールがない、請求項1または請求項2に記載の生物学的流体フィルタアセンブリ。
- 前記入口ポートは、前記フレームに前記入口側において取り付けられている前記可撓性ハウジング壁に取り付けられており、前記出口ポートは、前記出口側において取り付けられている前記可撓性ハウジング壁に取り付けられている、請求項1から請求項3までのいずれか1項に記載の生物学的流体フィルタアセンブリ。
- 前記入口ポートと前記出口ポートは前記フレームとともに一体的に成型されている、請求項1から請求項4までのいずれか1項に記載の生物学的流体フィルタアセンブリ。
- 前記フレームはポリ塩化ビニルを含む、請求項1から請求項5までのいずれか1項に記載の生物学的流体フィルタアセンブリ。
- 前記可撓性ハウジング壁の少なくとも1つはポリ塩化ビニルを含む材質によって形成されている、請求項1から請求項6までのいずれか1項に記載の生物学的流体フィルタアセンブリ。
- 前記ろ過媒体は第1のろ過要素と第2のろ過要素を備える、請求項1から請求項7までのいずれか1項に記載の生物学的流体フィルタアセンブリ。
- 少なくとも1つの前記ろ過要素は、血液または血液成分から白血球を除去するために適した多孔性を有する非織物の繊維材料を備える、請求項8に記載の生物学的流体フィルタアセンブリ。
- 1つの前記ろ過要素は、血液または血液成分から微小凝集体を除去するために適した多孔性を有する非織物の繊維材料を備える、請求項8または請求項9に記載の生物学的流体フィルタアセンブリ。
- 少なくとも1つの前記ろ過要素は、ポリエチレンテレフタレート、ポリブチレンテレフタレート、および、ポリプロピレンからなる群から選択されるメルトブローン材料を含む、請求項8から請求項10までのいずれか1項に記載の生物学的流体フィルタアセンブリ。
- a)複数の積層されたシートを備え、入口側と出口側を有するろ過媒体を組み立て;
b)前記ろ過媒体の前記入口側の上方に1つのハウジング壁を配置し、前記ろ過媒体の前記出口側の下方に1つのハウジング壁を配置し;
c)外周の周端を規定し、入口側と出口側を備える前記ろ過媒体と前記ハウジング壁を成型装置の空洞内に配置し;
d)前記ろ過媒体と前記ハウジング壁の前記周端周りにフレームを形成するために融解した高分子材料を前記空洞内に導入し、前記ろ過媒体と前記ハウジング壁を前記フレーム内に捉え、前記フレームは1組の中央開口を前記ろ過媒体の前記入口側と前記出口側に規定することを含む、請求項1から請求項11までのいずれか1項に記載の生物学的流体フィルタアセンブリの作製方法。 - さらにポートを前記可撓性ハウジング壁のそれぞれに取り付けることを含む、請求項12に記載の方法。
- 多孔性シートの積層を組み立てることにより前記ろ過媒体を形成することを含む、請求項12または請求項13に記載の方法。
- フィルターパッドを提供するために前記積層を切断することをさらに含む、請求項14に記載の方法。
- 前記融解した高分子材料はポリ塩化ビニルを含む、請求項12から請求項15までのいずれか1項に記載の方法。
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US14/223,831 | 2014-03-24 | ||
US14/223,831 US9968738B2 (en) | 2014-03-24 | 2014-03-24 | Biological fluid filters with molded frame and methods for making such filters |
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JP2019118482A Active JP6959298B2 (ja) | 2014-03-24 | 2019-06-26 | 成型フレームを有する生物学的流体フィルタとそのフィルタの作製方法 |
JP2020077189A Active JP7277413B2 (ja) | 2014-03-24 | 2020-04-24 | 成型フレームを有する生物学的流体フィルタとそのフィルタの作製方法 |
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EP (1) | EP3122397B1 (ja) |
JP (3) | JP2017508554A (ja) |
CN (1) | CN106132453A (ja) |
AU (1) | AU2014388298B2 (ja) |
BR (1) | BR112016020961B1 (ja) |
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US10159778B2 (en) | 2014-03-24 | 2018-12-25 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
US10376620B2 (en) | 2015-04-02 | 2019-08-13 | Fenwal, Inc. | Systems and methods for leukoreducing a red blood cell-containing fluid and concentrated red blood cells |
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US10857269B2 (en) | 2016-08-24 | 2020-12-08 | Fenwal, Inc. | Cassette having an integrated filter and bypass |
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