JP2010518140A - Igf−1rに対する新規抗体 - Google Patents

Igf−1rに対する新規抗体 Download PDF

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Publication number
JP2010518140A
JP2010518140A JP2009549402A JP2009549402A JP2010518140A JP 2010518140 A JP2010518140 A JP 2010518140A JP 2009549402 A JP2009549402 A JP 2009549402A JP 2009549402 A JP2009549402 A JP 2009549402A JP 2010518140 A JP2010518140 A JP 2010518140A
Authority
JP
Japan
Prior art keywords
antibody
antigen
seq
binding fragment
igf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009549402A
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English (en)
Japanese (ja)
Other versions
JP2010518140A5 (es
Inventor
バーデン,マイケル,ニール
エリス,ジョナサン,ヘンリー
ハンブリン,ポール,アンドリュー
ルイス,アラン,ピーター
シャー,ラドハ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0702888.9A external-priority patent/GB0702888D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JP2010518140A publication Critical patent/JP2010518140A/ja
Publication of JP2010518140A5 publication Critical patent/JP2010518140A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
JP2009549402A 2007-02-14 2008-02-12 Igf−1rに対する新規抗体 Pending JP2010518140A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0702888.9A GB0702888D0 (en) 2007-02-14 2007-02-14 Novel Antibodies
US95321007P 2007-08-01 2007-08-01
PCT/EP2008/051655 WO2008098917A2 (en) 2007-02-14 2008-02-12 Novel antibodies against igf-ir

Publications (2)

Publication Number Publication Date
JP2010518140A true JP2010518140A (ja) 2010-05-27
JP2010518140A5 JP2010518140A5 (es) 2010-09-30

Family

ID=42025950

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009549402A Pending JP2010518140A (ja) 2007-02-14 2008-02-12 Igf−1rに対する新規抗体

Country Status (5)

Country Link
JP (1) JP2010518140A (es)
KR (1) KR20090114449A (es)
EA (1) EA200900991A1 (es)
MX (1) MX2009008754A (es)
PE (1) PE20090107A1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015505843A (ja) * 2011-12-15 2015-02-26 ザ・ロイヤル・インスティテューション・フォア・ザ・アドバンスメント・オブ・ラーニング/マクギル・ユニヴァーシティ 可溶性IGFレセプターFc融合タンパク質およびその使用
JP2019501631A (ja) * 2015-10-23 2019-01-24 アポジェニックス アーゲー 一本鎖gitr受容体アゴニストタンパク質

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3027824A1 (en) 2010-02-23 2011-09-01 Sanofi Anti-alpha2 integrin antibodies and their uses
TWI560199B (en) 2010-08-31 2016-12-01 Sanofi Sa Peptide or peptide complex binding to α2 integrin and methods and uses involving the same

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053596A2 (en) * 2001-01-05 2002-07-11 Pfizer Inc. Antibodies to insulin-like growth factor i receptor
WO2003106621A2 (en) * 2002-06-14 2003-12-24 Immunogen, Inc. Anti-igf-i receptor antibody
WO2005016970A2 (en) * 2003-05-01 2005-02-24 Imclone Systems Incorporated Fully human antibodies directed against the human insulin-like growth factor-1 receptor
WO2005058967A2 (en) * 2003-12-16 2005-06-30 Pierre Fabre Medicament Novel anti-insulin/igf-i hybrid receptor or anti-insulin/igf-i hybrid receptor and igf-ir antibodies and uses thereof
WO2005061541A1 (en) * 2002-06-14 2005-07-07 Immunogen, Inc. Anti-igf-i receptor antibody
WO2006013472A2 (en) * 2004-07-29 2006-02-09 Pierre Fabre Medicament Novel anti-igf-ir antibodies and uses thereof
WO2007000328A1 (en) * 2005-06-27 2007-01-04 Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa Antibodies that bind to an epitope on insulin-like growth factor 1 receptor and uses thereof
WO2007012614A2 (en) * 2005-07-22 2007-02-01 Pierre Fabre Medicament Novel anti-igf-ir antibodies and uses thereof

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053596A2 (en) * 2001-01-05 2002-07-11 Pfizer Inc. Antibodies to insulin-like growth factor i receptor
WO2003106621A2 (en) * 2002-06-14 2003-12-24 Immunogen, Inc. Anti-igf-i receptor antibody
WO2005061541A1 (en) * 2002-06-14 2005-07-07 Immunogen, Inc. Anti-igf-i receptor antibody
WO2005016970A2 (en) * 2003-05-01 2005-02-24 Imclone Systems Incorporated Fully human antibodies directed against the human insulin-like growth factor-1 receptor
WO2005058967A2 (en) * 2003-12-16 2005-06-30 Pierre Fabre Medicament Novel anti-insulin/igf-i hybrid receptor or anti-insulin/igf-i hybrid receptor and igf-ir antibodies and uses thereof
WO2006013472A2 (en) * 2004-07-29 2006-02-09 Pierre Fabre Medicament Novel anti-igf-ir antibodies and uses thereof
WO2007000328A1 (en) * 2005-06-27 2007-01-04 Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa Antibodies that bind to an epitope on insulin-like growth factor 1 receptor and uses thereof
WO2007012614A2 (en) * 2005-07-22 2007-02-01 Pierre Fabre Medicament Novel anti-igf-ir antibodies and uses thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015505843A (ja) * 2011-12-15 2015-02-26 ザ・ロイヤル・インスティテューション・フォア・ザ・アドバンスメント・オブ・ラーニング/マクギル・ユニヴァーシティ 可溶性IGFレセプターFc融合タンパク質およびその使用
JP2019501631A (ja) * 2015-10-23 2019-01-24 アポジェニックス アーゲー 一本鎖gitr受容体アゴニストタンパク質

Also Published As

Publication number Publication date
MX2009008754A (es) 2009-11-02
EA200900991A1 (ru) 2010-02-26
KR20090114449A (ko) 2009-11-03
PE20090107A1 (es) 2009-03-20

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