IL52318A - Process of selectively blocking amino groups and some 4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols having selectively blocked amino groups - Google Patents

Process of selectively blocking amino groups and some 4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols having selectively blocked amino groups

Info

Publication number
IL52318A
IL52318A IL52318A IL5231877A IL52318A IL 52318 A IL52318 A IL 52318A IL 52318 A IL52318 A IL 52318A IL 5231877 A IL5231877 A IL 5231877A IL 52318 A IL52318 A IL 52318A
Authority
IL
Israel
Prior art keywords
amino groups
selectively
diaminocyclitols
aminoglycosyl
selectively blocking
Prior art date
Application number
IL52318A
Other languages
English (en)
Other versions
IL52318A0 (en
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of IL52318A0 publication Critical patent/IL52318A0/xx
Publication of IL52318A publication Critical patent/IL52318A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/238—Cyclohexane rings substituted by two guanidine radicals, e.g. streptomycins
IL52318A 1976-06-17 1977-06-14 Process of selectively blocking amino groups and some 4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols having selectively blocked amino groups IL52318A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/697,297 US4136254A (en) 1976-06-17 1976-06-17 Process of selectively blocking amino functions in aminoglycosides using transition metal salts and intermediates used thereby

Publications (2)

Publication Number Publication Date
IL52318A0 IL52318A0 (en) 1977-08-31
IL52318A true IL52318A (en) 1981-06-29

Family

ID=24800569

Family Applications (1)

Application Number Title Priority Date Filing Date
IL52318A IL52318A (en) 1976-06-17 1977-06-14 Process of selectively blocking amino groups and some 4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols having selectively blocked amino groups

Country Status (18)

Country Link
US (1) US4136254A (xx)
JP (5) JPS52153944A (xx)
AR (1) AR216648A1 (xx)
BE (1) BE855704A (xx)
CA (1) CA1265130A (xx)
CH (1) CH639979A5 (xx)
DE (3) DE2759974C2 (xx)
DK (1) DK165451C (xx)
ES (1) ES459791A1 (xx)
FR (2) FR2374331A1 (xx)
GB (1) GB1575982A (xx)
HK (1) HK484A (xx)
HU (1) HU182050B (xx)
IE (1) IE45734B1 (xx)
IL (1) IL52318A (xx)
MY (1) MY8500081A (xx)
NL (1) NL177014C (xx)
SE (2) SE447481B (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE48972B1 (en) * 1978-11-11 1985-06-26 Microbial Chem Res Found The production of a selectively protected n-acylated derivative of an aminoglycosidic antibiotic
US4226980A (en) * 1978-12-07 1980-10-07 Abbott Laboratories Novel derivatives of fortimicin B and process for preparing same
JPS5723281A (en) * 1980-07-17 1982-02-06 Mitsubishi Electric Corp Semiconductor light-receiving element
US4424344A (en) 1980-09-22 1984-01-03 Eli Lilly And Company 2-N-Acylated and 2-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process
US4424345A (en) 1980-09-22 1984-01-03 Eli Lilly And Company 1-N-Acylated and 1-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process
EP0054514A1 (de) * 1980-12-16 1982-06-23 Ciba-Geigy Ag Neue antibiotisch wirksame Aminopapulacandin-Derivate
JPS6253997A (ja) * 1985-09-03 1987-03-09 Kowa Co 新規なアミノ配糖体及びこれを含有する製剤
JPS6281784A (ja) * 1985-10-04 1987-04-15 Nippon Telegr & Teleph Corp <Ntt> 半導体レ−ザの発光強度監視方法および半導体レ−ザ装置
IT1200774B (it) * 1985-10-10 1989-01-27 Pierrel Spa Procedimento di sentisi dell'amikacina
IT1225484B (it) * 1987-11-27 1990-11-14 Pierrel Spa Procedimento di sintesi dell'amikacina
HU207338B (en) * 1989-06-21 1993-03-29 Schering Corp Process for producing izepamycin
US5442047A (en) * 1991-12-04 1995-08-15 Schering Corporation Process for preparing isepamicin
IT1237490B (it) * 1989-09-22 1993-06-07 Chementecno S R L Monza Milano Procedimento per la sintesi della 1 n (s delta ammino alfa idrossibutirril)kamanycin a basato sul trattamento della 1 n (s delta benzilossicarbonilammino alfa idrossibutirril) 3,6' di n benzilossicarbonilkanamycin a con acido formico
CN1040177C (zh) * 1993-04-23 1998-10-14 江苏省微生物研究所 一种含1-N-乙基庆大霉素C1a或其盐的药用制剂及制备方法
KR100467506B1 (ko) * 2002-10-01 2005-01-24 경동제약 주식회사 이세파마이신의 제조방법
US7794713B2 (en) * 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US20080213274A1 (en) * 2005-10-28 2008-09-04 Sabbadini Roger A Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
US20090074720A1 (en) * 2005-10-28 2009-03-19 Sabbadini Roger A Methods for decreasing immune response and treating immune conditions
US7862812B2 (en) * 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
CN101868472B (zh) 2007-11-21 2013-05-29 尔察祯有限公司 抗菌性氨基糖苷类似物
EP2421877A4 (en) 2008-10-03 2013-03-20 Glycan Biosciences Llc ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin
WO2010132757A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3388141A (en) * 1965-10-05 1968-06-11 Thiokol Chemical Corp Di-schiff bases of hydroxyl substituted diamines and beta-diketones, derivatives, and metal chelates thereof
FR2015139A1 (xx) * 1968-08-06 1970-04-24 Sanyo Chemical Cy Ltd
DE2061537A1 (de) * 1969-12-30 1971-07-08 Snam Progetti S.P.A., Mailand (Italien) Verfahren zur Herstellung von Kobalt(III>Komplexen
US3682995A (en) * 1970-05-04 1972-08-08 Minnesota Mining & Mfg Copper chelate
JPS5220991B2 (xx) * 1972-08-23 1977-06-07
US4001208A (en) 1972-10-06 1977-01-04 Zaidan Hojin Biseibutsu Kagaku Kenkyo Kai 1-N-[(S)-α-hydroxy-ω-aminoacyl]
GB1441202A (en) * 1973-05-15 1976-06-30 Microbial Chem Res Found 1-n-isoserylkanamycins and the production thereof
US3878193A (en) * 1973-06-26 1975-04-15 Schering Corp Process for the preparation of garamine derivatives
US3872080A (en) * 1973-06-26 1975-03-18 Schering Corp Process for the preparation of garamine and intermediates produced thereby
JPS5512039B2 (xx) * 1974-03-22 1980-03-29
JPS573679B2 (xx) * 1974-03-07 1982-01-22
AR207582A1 (es) * 1974-03-19 1976-10-15 Scherico Ltd Procedimiento para preparar derivados de diaminociclitole
JPS5564598A (en) * 1978-11-11 1980-05-15 Microbial Chem Res Found Preparation of aminoglycoside antibiotic having selectively protected amino group

Also Published As

Publication number Publication date
SE7706872L (sv) 1978-02-06
JPS5576895A (en) 1980-06-10
IL52318A0 (en) 1977-08-31
JPS6121558B2 (xx) 1986-05-27
JPS52153944A (en) 1977-12-21
DE2759974C2 (xx) 1988-05-26
JPS5549586B2 (xx) 1980-12-12
JPS5569598A (en) 1980-05-26
DK165451B (da) 1992-11-30
DK263277A (da) 1977-12-18
CH639979A5 (de) 1983-12-15
FR2395277B1 (xx) 1981-11-20
SE8601074D0 (sv) 1986-03-07
BE855704A (fr) 1977-12-15
SE469131B (sv) 1993-05-17
SE8601074A (xx) 1986-03-07
DE2760317C2 (xx) 1987-11-26
FR2395277A1 (fr) 1979-01-19
US4136254A (en) 1979-01-23
DE2726712A1 (de) 1977-12-22
ES459791A1 (es) 1978-08-16
JPS5822160B2 (ja) 1983-05-06
JPS6127997A (ja) 1986-02-07
JPH0132232B2 (xx) 1989-06-29
JPS6227073B2 (xx) 1987-06-12
MY8500081A (en) 1985-12-31
AR216648A1 (es) 1980-01-15
DK165451C (da) 1993-04-13
JPS5569519A (en) 1980-05-26
IE45734L (en) 1977-12-17
HK484A (en) 1984-01-13
GB1575982A (en) 1980-10-01
DE2726712C2 (xx) 1987-06-19
FR2374331B1 (xx) 1981-07-31
HU182050B (en) 1983-12-28
FR2374331A1 (fr) 1978-07-13
CA1265130A (en) 1990-01-30
IE45734B1 (en) 1982-11-17
NL177014C (nl) 1985-07-16
NL177014B (nl) 1985-02-18
NL7706596A (nl) 1977-12-20
SE447481B (sv) 1986-11-17

Similar Documents

Publication Publication Date Title
IL52318A (en) Process of selectively blocking amino groups and some 4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols having selectively blocked amino groups
GB1540351A (en) N-benzoyl n&#39;-pyridyloxy phenyl urea and preparation thereof
GB1521930A (en) N,n&#39;-di-(hydroxybenzyl)-1,3-propane and 1,3-propane-2-ol-n,n&#39;-diacetonitriles
PH15120A (en) 6-phenyl-4h-s-triazolo-(3,4c)-1,4-diazepine and salts thereof
GB1531522A (en) N-2,3-dihydroxypropyl-n-2&#39;-hydroxy-alkyl amines and their salts
AU511854B2 (en) Fabric treatment processes and compositions
JPS52133982A (en) Novel imidazolyll*4**oxyypropanolamine derivartive* prparation thereof and medicine containing same and having barrier effect against betaaacceptor
JPS52139040A (en) 22 and 33substituted enekephlin
NZ188147A (en) 4, 6-di-o-(aminoglycosyl)-1, 3-diaminocyclitol antibiotics and pharmaceutical compositions
DE2861947D1 (en) Selectively protected 4,6-di-o-(aminoglycosyl)-1,3-diamino-cyclitols
NZ184529A (en) 5-isopropylidene-7-hydroxy-9-substituted-2,6-methano-3,4,56-tetrahydro-2h-1-benzoxocins and their preparation
JPS5335025A (en) Crossslinked acrylonitrile copolymer
JPS527966A (en) 99hydroxyy7*8*9*100tetrahydroo 6hhdibenzo*b**d*bilanes and bilanones
JPS533535A (en) Tremor treating agent in parkinsons disease
JPS5365853A (en) 15 * 166dihydroxyprostaglandin and like
GB2075982B (en) 1-3-dihydroxy-27-nor-cholesta-5-en and 5,7-dien-25-one
GB1538368A (en) 1,3,4,6-tetrathia and tetraselena-2,5-dihetero-pentalene compounds
GB1538438A (en) 5-n-(3-amino-2-hydroxy-propyl)-amino-1,2,4-oxadiazole derivatives processes for their preparation and applications thereof
JPS5372100A (en) Improved block copolymer and its manufacture
JPS51113875A (en) 10*111dihydroo33carboxycyproheptadine and nnoxide
JPS5251361A (en) Substituted 4*5*6*77 tetrahydroo77iminobenzoo and 77oxybenzo*b*thienn 44yl urea
GB1486546A (en) 4,4-diphenyl-cyclohexylpiperidine compounds and analogues thereof
ZA777610B (en) 1,4-oxathianes and the preparation thereof
JPS5328169A (en) Novel peptide and antibacterial agent
JPS51110097A (en) Koseibutsushitsu 77 * 55 amino 55 karubokishibareruamido * 33 karubamoirokishimechiru 77 metokishi 33 sefuemu 44 karubonsannoseizoho