IL47314A - Derivatives of biphenylylalkyl alkyl sulfones and sulfoxides, their preparation and pharmaceutical compositions containing them - Google Patents
Derivatives of biphenylylalkyl alkyl sulfones and sulfoxides, their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL47314A IL47314A IL47314A IL4731475A IL47314A IL 47314 A IL47314 A IL 47314A IL 47314 A IL47314 A IL 47314A IL 4731475 A IL4731475 A IL 4731475A IL 47314 A IL47314 A IL 47314A
- Authority
- IL
- Israel
- Prior art keywords
- biphenylylalkyl
- sulfoxides
- derivatives
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/02—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms
- C07C317/10—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/16—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/45—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms doubly-bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/65—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfone or sulfoxide groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2424475A DE2424475C3 (de) | 1974-05-20 | 1974-05-20 | Neue Biphenylsulfoxide, deren Diastereomere und optisch aktive Antipoden |
DE19752500944 DE2500944A1 (de) | 1974-05-20 | 1975-01-11 | Neue sulfoxide |
DE19752503770 DE2503770A1 (de) | 1974-05-20 | 1975-01-30 | Neue sulfoxide |
DE19752508244 DE2508244A1 (de) | 1974-05-20 | 1975-02-26 | Neue sulfone |
DE19752508243 DE2508243A1 (de) | 1974-05-20 | 1975-02-26 | Neue sulfoxide |
Publications (2)
Publication Number | Publication Date |
---|---|
IL47314A0 IL47314A0 (en) | 1975-07-28 |
IL47314A true IL47314A (en) | 1979-05-31 |
Family
ID=27510355
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL47314A IL47314A (en) | 1974-05-20 | 1975-05-19 | Derivatives of biphenylylalkyl alkyl sulfones and sulfoxides, their preparation and pharmaceutical compositions containing them |
Country Status (20)
Country | Link |
---|---|
US (2) | US3993683A (no) |
JP (1) | JPS50160243A (no) |
AT (4) | AT336589B (no) |
BE (1) | BE829256A (no) |
CA (1) | CA1064032A (no) |
CS (1) | CS190478B2 (no) |
DD (1) | DD119783A5 (no) |
DK (1) | DK217375A (no) |
FI (1) | FI751334A (no) |
FR (1) | FR2271810B1 (no) |
GB (1) | GB1469083A (no) |
HU (1) | HU170754B (no) |
IE (1) | IE41149B1 (no) |
IL (1) | IL47314A (no) |
LU (1) | LU72534A1 (no) |
NL (1) | NL7505878A (no) |
NO (1) | NO141013C (no) |
PL (1) | PL100910B1 (no) |
RO (1) | RO73127A (no) |
SE (1) | SE7505749L (no) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2546319C2 (de) * | 1975-10-16 | 1986-02-27 | Dr. Karl Thomae Gmbh, 7950 Biberach | Cyclohexylphenyl-Derivate, Verfahren zu deren Herstellung und diese enthaltende Mittel |
GB1584462A (en) * | 1977-03-31 | 1981-02-11 | Lafon Labor | N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them |
JPS54129687U (no) * | 1978-02-15 | 1979-09-08 | ||
FR2528041A1 (fr) * | 1982-06-04 | 1983-12-09 | Lafon Labor | Acides halogenobenzhydrylsulfinylacetohydroxamiques, procede de preparation et utilisation en therapeutique |
GB8311678D0 (en) * | 1983-04-28 | 1983-06-02 | Ici Plc | Phenol derivatives |
DE3332692A1 (de) * | 1983-09-10 | 1985-03-28 | Merck Patent Gmbh, 6100 Darmstadt | Anisotrope verbindungen und fluessigkristallmischungen |
US5252252A (en) * | 1983-09-10 | 1993-10-12 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Anisotropic compounds and liquid crystal mixtures |
IE58417B1 (en) * | 1984-04-27 | 1993-09-22 | Ici Plc | Chemical derivatives |
DE3724669A1 (de) * | 1987-07-25 | 1989-02-02 | Hoechst Ag | Leukotrienantagonisten, verfahren zu ihrer herstellung und ihre anwendung zur behandlung von krankheiten |
DE3724735A1 (de) * | 1987-07-25 | 1989-02-02 | Hoechst Ag | Leukotrienantagonisten, verfahren zu ihrer herstellung, ihre anwendung zur behandlung von krankheiten, sowie vorprodukte |
US5256692A (en) * | 1992-01-07 | 1993-10-26 | E. R. Squibb & Sons, Inc. | Sulfur-containing HMG-COA reductase inhibitors |
US5789434A (en) * | 1994-11-15 | 1998-08-04 | Bayer Corporation | Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors |
AR002945A1 (es) * | 1994-11-15 | 1998-05-27 | Bayer Corp | Acidos 4-biarilbutirico o 5-biarilpentanoico sustituidos y sus derivados como inhibidores de las metaloproteasas de matriz, composicion que los contiene, y metodos para la preparacion de dichos compuestos |
US5856339A (en) * | 1995-02-28 | 1999-01-05 | Eli Lilly And Company | Benzothiophene compounds, intermediates, compositions, and methods |
US5856340A (en) * | 1995-02-28 | 1999-01-05 | Eli Lilly And Company | Method of treating estrogen dependent cancers |
KR100809489B1 (ko) * | 2001-10-10 | 2008-03-03 | 씨제이제일제당 (주) | 사이클로옥시게나제-2의 저해제로서 선택성이 뛰어난4'-메탄설포닐-비페닐 유도체 |
US20060276539A1 (en) * | 2002-10-16 | 2006-12-07 | Dalton James T | Treating Androgen Decline in Aging Male (ADAM)- associated conditions with SARMS |
EP1586559A1 (en) * | 2004-04-13 | 2005-10-19 | Cephalon, Inc. | Biaryl-methanethio-, -sulphinyl- and sulphonyl derivatives |
US7449481B2 (en) * | 2004-04-13 | 2008-11-11 | Cephalon, Inc. | Thio-substituted biaryl-methanesulfinyl derivatives |
JP2008520683A (ja) * | 2004-11-18 | 2008-06-19 | ジ インスチチュート フォー ファーマシューティカル ディスカバリー、エルエルシー | タンパク質チロシンホスファターゼ阻害剤としてのヘテロシクリルビフェニル誘導体 |
US8013150B2 (en) * | 2005-06-22 | 2011-09-06 | Msn Laboratories Ltd. | Process for the preparation of ezetimibe |
US8818322B2 (en) * | 2006-06-09 | 2014-08-26 | Trapeze Networks, Inc. | Untethered access point mesh system and method |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1121722A (en) * | 1966-03-31 | 1968-07-31 | Ici Ltd | New carboxylic acid derivatives |
GB1121027A (en) * | 1966-06-23 | 1968-07-24 | Ici Ltd | New carboxylic acid derivatives, processes for the preparation thereof and compositions containing the same |
GB1140748A (en) * | 1966-06-23 | 1969-01-22 | Ici Ltd | New carboxylic acid derivatives |
-
1975
- 1975-04-09 AT AT267375A patent/AT336589B/de not_active IP Right Cessation
- 1975-04-16 NO NO751358A patent/NO141013C/no unknown
- 1975-05-06 FI FI751334A patent/FI751334A/fi not_active Application Discontinuation
- 1975-05-12 CS CS753282A patent/CS190478B2/cs unknown
- 1975-05-14 US US05/577,169 patent/US3993683A/en not_active Expired - Lifetime
- 1975-05-16 DK DK217375A patent/DK217375A/da unknown
- 1975-05-16 CA CA227,151A patent/CA1064032A/en not_active Expired
- 1975-05-16 DD DD186100A patent/DD119783A5/xx unknown
- 1975-05-19 JP JP50059542A patent/JPS50160243A/ja active Pending
- 1975-05-19 HU HUTO1003A patent/HU170754B/hu unknown
- 1975-05-19 PL PL1975180524A patent/PL100910B1/pl unknown
- 1975-05-19 GB GB2126775A patent/GB1469083A/en not_active Expired
- 1975-05-19 IL IL47314A patent/IL47314A/xx unknown
- 1975-05-19 RO RO7582278A patent/RO73127A/ro unknown
- 1975-05-20 BE BE156504A patent/BE829256A/xx unknown
- 1975-05-20 FR FR7515636A patent/FR2271810B1/fr not_active Expired
- 1975-05-20 NL NL7505878A patent/NL7505878A/xx not_active Application Discontinuation
- 1975-05-20 IE IE1132/75A patent/IE41149B1/xx unknown
- 1975-05-20 LU LU72534A patent/LU72534A1/xx unknown
- 1975-05-20 SE SE7505749A patent/SE7505749L/xx not_active Application Discontinuation
-
1976
- 1976-06-11 AT AT434976A patent/AT344149B/de not_active IP Right Cessation
-
1977
- 1977-07-18 AT AT515777A patent/AT346833B/de not_active IP Right Cessation
- 1977-07-18 AT AT515877A patent/AT346834B/de not_active IP Right Cessation
- 1977-11-18 US US05/852,714 patent/US4191776A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NO141013B (no) | 1979-09-17 |
FR2271810A1 (no) | 1975-12-19 |
AT346834B (de) | 1978-11-27 |
CS190478B2 (en) | 1979-05-31 |
SE7505749L (sv) | 1975-11-21 |
NL7505878A (nl) | 1975-11-24 |
DD119783A5 (no) | 1976-05-12 |
DK217375A (da) | 1975-11-21 |
ATA434976A (de) | 1977-11-15 |
FR2271810B1 (no) | 1979-08-10 |
LU72534A1 (no) | 1977-02-10 |
PL100910B1 (pl) | 1978-11-30 |
GB1469083A (en) | 1977-03-30 |
HU170754B (no) | 1977-08-28 |
IL47314A0 (en) | 1975-07-28 |
IE41149L (en) | 1975-11-20 |
BE829256A (fr) | 1975-11-20 |
RO73127A (ro) | 1981-11-04 |
JPS50160243A (no) | 1975-12-25 |
CA1064032A (en) | 1979-10-09 |
US3993683A (en) | 1976-11-23 |
AT346833B (de) | 1978-11-27 |
US4191776A (en) | 1980-03-04 |
ATA267375A (de) | 1976-09-15 |
ATA515877A (de) | 1978-04-15 |
IE41149B1 (en) | 1979-10-24 |
NO141013C (no) | 1979-12-27 |
FI751334A (no) | 1975-11-21 |
AT344149B (de) | 1978-07-10 |
AT336589B (de) | 1977-05-10 |
ATA515777A (de) | 1978-04-15 |
NO751358L (no) | 1975-11-21 |
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