IL251441B - תולדות אימידזו פירידין ותכשירי רוקחות המכילים אותן - Google Patents

תולדות אימידזו פירידין ותכשירי רוקחות המכילים אותן

Info

Publication number
IL251441B
IL251441B IL251441A IL25144117A IL251441B IL 251441 B IL251441 B IL 251441B IL 251441 A IL251441 A IL 251441A IL 25144117 A IL25144117 A IL 25144117A IL 251441 B IL251441 B IL 251441B
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
compositions containing
pyridine derivatives
imidazo pyridine
imidazo
Prior art date
Application number
IL251441A
Other languages
English (en)
Other versions
IL251441A0 (he
Inventor
Pascale Gaillard
Jeyaprakashnarayanan Seenisamy
Lesley Liu-Bujalski
Justin Potnick
richard d Caldwell
Hui Qiu
Constantin Neagu
Reinaldo Jones
Annie Cho Won
Andreas Goutopoulos
Brian Sherer
Theresa L Johnson
Anna Gardberg
Original Assignee
Merck Patent Gmbh
Pascale Gaillard
Jeyaprakashnarayanan Seenisamy
Liu Bujalski Lesley
Justin Potnick
richard d Caldwell
Hui Qiu
Constantin Neagu
Reinaldo Jones
Annie Cho Won
Andreas Goutopoulos
Brian Sherer
Theresa L Johnson
Anna Gardberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54337891&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL251441(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh, Pascale Gaillard, Jeyaprakashnarayanan Seenisamy, Liu Bujalski Lesley, Justin Potnick, richard d Caldwell, Hui Qiu, Constantin Neagu, Reinaldo Jones, Annie Cho Won, Andreas Goutopoulos, Brian Sherer, Theresa L Johnson, Anna Gardberg filed Critical Merck Patent Gmbh
Publication of IL251441A0 publication Critical patent/IL251441A0/he
Publication of IL251441B publication Critical patent/IL251441B/he

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
IL251441A 2014-10-06 2017-03-29 תולדות אימידזו פירידין ותכשירי רוקחות המכילים אותן IL251441B (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462060249P 2014-10-06 2014-10-06
PCT/US2015/054221 WO2016057500A1 (en) 2014-10-06 2015-10-06 Heteroaryl compounds as btk inhibitors and uses thereof

Publications (2)

Publication Number Publication Date
IL251441A0 IL251441A0 (he) 2017-05-29
IL251441B true IL251441B (he) 2020-06-30

Family

ID=54337891

Family Applications (1)

Application Number Title Priority Date Filing Date
IL251441A IL251441B (he) 2014-10-06 2017-03-29 תולדות אימידזו פירידין ותכשירי רוקחות המכילים אותן

Country Status (19)

Country Link
US (2) US10253023B2 (he)
EP (1) EP3204382B1 (he)
JP (1) JP6856526B2 (he)
KR (1) KR102523111B1 (he)
CN (1) CN107001362A (he)
AR (1) AR102177A1 (he)
AU (1) AU2015328285B2 (he)
BR (1) BR112017006305B1 (he)
CA (1) CA2960401C (he)
CL (1) CL2017000786A1 (he)
ES (1) ES2907622T3 (he)
IL (1) IL251441B (he)
MX (1) MX2017004200A (he)
NZ (1) NZ729603A (he)
PH (1) PH12017500408B1 (he)
RU (1) RU2742122C2 (he)
SG (1) SG11201701573QA (he)
WO (1) WO2016057500A1 (he)
ZA (1) ZA201701501B (he)

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TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
US20170342060A1 (en) 2016-05-26 2017-11-30 Incyte Corporation Heterocyclic compounds as immunomodulators
CA3028685A1 (en) 2016-06-20 2017-12-28 Incyte Corporation Heterocyclic compounds as immunomodulators
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CN109641892B (zh) * 2016-08-16 2021-07-02 默克专利有限公司 用作可逆btk抑制剂的2-氧代-咪唑并吡啶及其用途
EP3504198B1 (en) 2016-08-29 2023-01-25 Incyte Corporation Heterocyclic compounds as immunomodulators
TW202241895A (zh) 2016-09-09 2022-11-01 美商英塞特公司 吡唑并吡啶化合物及其用途
US20180072718A1 (en) 2016-09-09 2018-03-15 Incyte Corporation Pyrazolopyridine compounds and uses thereof
WO2018049152A1 (en) 2016-09-09 2018-03-15 Incyte Corporation Pyrazolopyrimidine derivatives as hpk1 modulators and uses thereof for the treatment of cancer
US10280164B2 (en) 2016-09-09 2019-05-07 Incyte Corporation Pyrazolopyridone compounds and uses thereof
JP7149276B2 (ja) 2016-12-22 2022-10-06 インサイト・コーポレイション Ｐｄ－ｌ１内在化誘導物質としてのテトラヒドロイミダゾ［４，５－ｃ］ピリジン誘導体
AU2017382870B2 (en) 2016-12-22 2022-03-24 Incyte Corporation Benzooxazole derivatives as immunomodulators
ES2874756T3 (es) 2016-12-22 2021-11-05 Incyte Corp Derivados de triazolo[1,5-A]piridina como inmunomoduladores
EP3558973B1 (en) 2016-12-22 2021-09-15 Incyte Corporation Pyridine derivatives as immunomodulators
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CN106939009A (zh) * 2017-03-31 2017-07-11 牡丹江医学院 一种用于治疗脑震荡的药物及其制备方法
JOP20190233A1 (ar) * 2017-04-14 2019-10-02 Biogen Ma Inc نظائر بنزوازيبين بوصفها عوامل مثبطة لتيروزين كيناز بروتون
WO2019051199A1 (en) 2017-09-08 2019-03-14 Incyte Corporation 6-CYANO-INDAZOLE COMPOUNDS AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) MODULATORS
WO2019099294A1 (en) * 2017-11-14 2019-05-23 Merck Sharp & Dohme Corp. Novel substituted biaryl compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
US10745388B2 (en) 2018-02-20 2020-08-18 Incyte Corporation Indazole compounds and uses thereof
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