IL158969A0 - Modified antibodies to prostate-specific membrane antigen and uses thereof - Google Patents
Modified antibodies to prostate-specific membrane antigen and uses thereofInfo
- Publication number
- IL158969A0 IL158969A0 IL15896902A IL15896902A IL158969A0 IL 158969 A0 IL158969 A0 IL 158969A0 IL 15896902 A IL15896902 A IL 15896902A IL 15896902 A IL15896902 A IL 15896902A IL 158969 A0 IL158969 A0 IL 158969A0
- Authority
- IL
- Israel
- Prior art keywords
- antibodies
- psma
- antigen
- specific membrane
- membrane antigen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6869—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from a cell of the reproductive system: ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A61K51/1072—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from the reproductive system, e.g. ovaria, uterus, testes or prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29521401P | 2001-06-01 | 2001-06-01 | |
US32358501P | 2001-09-20 | 2001-09-20 | |
US36281002P | 2002-03-08 | 2002-03-08 | |
PCT/US2002/017068 WO2002098897A2 (en) | 2001-06-01 | 2002-05-30 | Modified antibodies to prostate-specific membrane antigen and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IL158969A0 true IL158969A0 (en) | 2004-05-12 |
Family
ID=27404335
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15896902A IL158969A0 (en) | 2001-06-01 | 2002-05-30 | Modified antibodies to prostate-specific membrane antigen and uses thereof |
IL158969A IL158969A (en) | 2001-06-01 | 2003-11-20 | Modified antibodies to prostate-specific membrane antigen and uses thereof |
IL201274A IL201274A (en) | 2001-06-01 | 2009-10-01 | Antibody to specific prostate cell membrane antigen and its use |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL158969A IL158969A (en) | 2001-06-01 | 2003-11-20 | Modified antibodies to prostate-specific membrane antigen and uses thereof |
IL201274A IL201274A (en) | 2001-06-01 | 2009-10-01 | Antibody to specific prostate cell membrane antigen and its use |
Country Status (10)
Country | Link |
---|---|
US (1) | US7045605B2 (ja) |
EP (2) | EP1392360B1 (ja) |
JP (2) | JP4619651B2 (ja) |
AT (1) | ATE535258T1 (ja) |
AU (1) | AU2002318169B2 (ja) |
CA (1) | CA2447695C (ja) |
HK (1) | HK1062915A1 (ja) |
IL (3) | IL158969A0 (ja) |
MX (1) | MXPA03010804A (ja) |
WO (1) | WO2002098897A2 (ja) |
Families Citing this family (107)
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US20040253246A1 (en) * | 1996-02-23 | 2004-12-16 | Israeli Ron S. | Prostate-specific membrane antigen and uses thereof |
US6107090A (en) | 1996-05-06 | 2000-08-22 | Cornell Research Foundation, Inc. | Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains |
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- 2002-05-30 US US10/160,505 patent/US7045605B2/en not_active Expired - Lifetime
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- 2002-05-30 EP EP10181902.7A patent/EP2277542B1/en not_active Expired - Lifetime
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US7045605B2 (en) | 2006-05-16 |
IL201274A (en) | 2015-04-30 |
WO2002098897A2 (en) | 2002-12-12 |
EP1392360B1 (en) | 2011-11-30 |
JP2004532639A (ja) | 2004-10-28 |
HK1062915A1 (en) | 2004-12-03 |
CA2447695A1 (en) | 2002-12-12 |
EP2277542A1 (en) | 2011-01-26 |
IL201274A0 (en) | 2011-07-31 |
CA2447695C (en) | 2015-02-24 |
EP1392360A2 (en) | 2004-03-03 |
EP1392360A4 (en) | 2005-07-20 |
AU2002318169B2 (en) | 2007-10-18 |
MXPA03010804A (es) | 2004-11-22 |
EP2277542B1 (en) | 2014-04-16 |
WO2002098897A3 (en) | 2003-05-01 |
JP4619651B2 (ja) | 2011-01-26 |
ATE535258T1 (de) | 2011-12-15 |
US20040213791A1 (en) | 2004-10-28 |
JP2010017189A (ja) | 2010-01-28 |
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