IT1291623B1 - Procedimento per la coniugazione di chelanti con molecole contenenti gruppi amminici - Google Patents

Procedimento per la coniugazione di chelanti con molecole contenenti gruppi amminici

Info

Publication number
IT1291623B1
IT1291623B1 IT97MI000929A ITMI970929A IT1291623B1 IT 1291623 B1 IT1291623 B1 IT 1291623B1 IT 97MI000929 A IT97MI000929 A IT 97MI000929A IT MI970929 A ITMI970929 A IT MI970929A IT 1291623 B1 IT1291623 B1 IT 1291623B1
Authority
IT
Italy
Prior art keywords
chelants
conjugation
procedure
amine groups
molecules containing
Prior art date
Application number
IT97MI000929A
Other languages
English (en)
Inventor
Federico Maisano
Luigia Gozzini
Original Assignee
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Spa filed Critical Bracco Spa
Priority to IT97MI000929A priority Critical patent/IT1291623B1/it
Priority to EP98106720A priority patent/EP0882454A3/en
Priority to JP10102656A priority patent/JPH1129593A/ja
Priority to US09/061,021 priority patent/US6022524A/en
Publication of ITMI970929A1 publication Critical patent/ITMI970929A1/it
Application granted granted Critical
Publication of IT1291623B1 publication Critical patent/IT1291623B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A61K49/143—Peptides, e.g. proteins the protein being an albumin, e.g. HSA, BSA, ovalbumin
IT97MI000929A 1997-04-18 1997-04-18 Procedimento per la coniugazione di chelanti con molecole contenenti gruppi amminici IT1291623B1 (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT97MI000929A IT1291623B1 (it) 1997-04-18 1997-04-18 Procedimento per la coniugazione di chelanti con molecole contenenti gruppi amminici
EP98106720A EP0882454A3 (en) 1997-04-18 1998-04-14 A process for the conjugation of chelants with molecules containing amino groups
JP10102656A JPH1129593A (ja) 1997-04-18 1998-04-14 アミノ基を含む分子とキレート化剤の結合方法
US09/061,021 US6022524A (en) 1997-04-18 1998-04-16 Process for the conjugation of chelants with molecules containing amino groups

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI000929A IT1291623B1 (it) 1997-04-18 1997-04-18 Procedimento per la coniugazione di chelanti con molecole contenenti gruppi amminici

Publications (2)

Publication Number Publication Date
ITMI970929A1 ITMI970929A1 (it) 1998-10-18
IT1291623B1 true IT1291623B1 (it) 1999-01-11

Family

ID=11376982

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97MI000929A IT1291623B1 (it) 1997-04-18 1997-04-18 Procedimento per la coniugazione di chelanti con molecole contenenti gruppi amminici

Country Status (4)

Country Link
US (1) US6022524A (it)
EP (1) EP0882454A3 (it)
JP (1) JPH1129593A (it)
IT (1) IT1291623B1 (it)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136311A (en) 1996-05-06 2000-10-24 Cornell Research Foundation, Inc. Treatment and diagnosis of cancer
US6107090A (en) 1996-05-06 2000-08-22 Cornell Research Foundation, Inc. Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains
DE19736472C1 (de) * 1997-08-21 1999-04-22 Bernhard Dr Sixt Verfahren zum Herstellen von weitgehend nebenwirkungsfreien Kontrastmitteln
US20030050452A1 (en) * 2000-12-26 2003-03-13 Yuji Hashiguchi Process for producing metal complex of aminooligosaccharide derivative
WO2002096460A1 (en) * 2001-05-30 2002-12-05 Cornell Research Foundation, Inc. Endopeptidase/anti-psma antibody fusion proteins for treatment of cancer
JP4619651B2 (ja) 2001-06-01 2011-01-26 コーネル・リサーチ・ファンデーション・インコーポレイテッド 前立腺特異的膜抗原に対する修飾抗体およびその使用
US7514078B2 (en) * 2001-06-01 2009-04-07 Cornell Research Foundation, Inc. Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies
TWI284539B (en) * 2001-07-30 2007-08-01 Epix Pharm Inc A method for making a magnetic resonance (MR) imaging agent, a MR imaging contrast agent, a method for altering stability of a peptide and a modified peptide
EP1427377A4 (en) 2001-09-20 2006-04-12 Cornell Res Foundation Inc METHOD AND COMPOSITIONS FOR TREATING OR PREVENTING SKIN DISEASES USING BINDERS SPECIFIC TO THE PROSTATE-SPECIFIC MEMBRANEANT
CA2499573A1 (en) 2002-09-24 2004-04-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method for convection enhanced delivery of therapeutic agents
US20040136998A1 (en) * 2002-10-30 2004-07-15 Bander Neil H. Methods and compositions for treating or preventing insulin-related disorders using binding agents specific for prostate specific membrane antigen
DE60323677D1 (de) 2003-01-10 2008-10-30 Millennium Pharm Inc Verfahren zur bestimmung des wiederauftretens von prostata krebs
US20050202020A1 (en) * 2004-01-09 2005-09-15 Jeffrey Ross Diagnosing and treating cancer
WO2005094882A1 (en) * 2004-03-03 2005-10-13 Millennium Pharmaceuticals, Inc. Modified antibodies to prostate-specific membrane antigen and uses thereof
CN1969190A (zh) * 2004-04-20 2007-05-23 爱默蕾大学 多峰性纳米结构，其制造方法以及其使用方法
DE102004039048A1 (de) * 2004-08-11 2006-02-23 Siemens Ag Verfahren und Einrichtung zur molekularen Bilderzeugung mit einer molekularen Sonde
PL1934252T3 (pl) * 2005-10-13 2015-10-30 Biocon Ltd Sposób wytwarzania koniugatów insuliny
US8658148B2 (en) 2007-06-22 2014-02-25 Genzyme Corporation Chemically modified dendrimers
US20090271021A1 (en) * 2008-04-28 2009-10-29 Popp Shane M Execution system for the monitoring and execution of insulin manufacture
EP2873679A1 (en) * 2013-11-13 2015-05-20 F.Hoffmann-La Roche Ag Camelid single-domain antibody directed against amyloid bêta and methods for producing conjugates thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4824986A (en) * 1985-04-26 1989-04-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Metal chelate protein conjugate
US5338532A (en) * 1986-08-18 1994-08-16 The Dow Chemical Company Starburst conjugates
US5554748A (en) * 1989-04-07 1996-09-10 Nycomed Salutar, Inc. Adducts of macrocyclic chelants
IT1283218B1 (it) * 1996-03-08 1998-04-16 Bracco Spa Polichelanti, loro complessi con ioni metallici, loro preparazione e loro usi

Also Published As

Publication number Publication date
EP0882454A2 (en) 1998-12-09
EP0882454A3 (en) 2000-11-08
JPH1129593A (ja) 1999-02-02
US6022524A (en) 2000-02-08
ITMI970929A1 (it) 1998-10-18

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Legal Events

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0001 Granted