IL157241A0 - Malic acid addition salts of terbinafine - Google Patents

Malic acid addition salts of terbinafine

Info

Publication number
IL157241A0
IL157241A0 IL15724102A IL15724102A IL157241A0 IL 157241 A0 IL157241 A0 IL 157241A0 IL 15724102 A IL15724102 A IL 15724102A IL 15724102 A IL15724102 A IL 15724102A IL 157241 A0 IL157241 A0 IL 157241A0
Authority
IL
Israel
Prior art keywords
malic acid
terbinafine
acid addition
addition salts
antimycotics
Prior art date
Application number
IL15724102A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL157241A0 publication Critical patent/IL157241A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/30—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Seasonings (AREA)
IL15724102A 2001-02-07 2002-02-06 Malic acid addition salts of terbinafine IL157241A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0103046.9A GB0103046D0 (en) 2001-02-07 2001-02-07 Organic Compounds
PCT/EP2002/001249 WO2002070455A1 (en) 2001-02-07 2002-02-06 Malic acid addition salts of terbinafine

Publications (1)

Publication Number Publication Date
IL157241A0 true IL157241A0 (en) 2004-02-19

Family

ID=9908301

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15724102A IL157241A0 (en) 2001-02-07 2002-02-06 Malic acid addition salts of terbinafine
IL157241A IL157241A (en) 2001-02-07 2003-08-04 Turbine finic acid adsorbent salts, processes for their manufacture and medicinal preparations containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL157241A IL157241A (en) 2001-02-07 2003-08-04 Turbine finic acid adsorbent salts, processes for their manufacture and medicinal preparations containing them

Country Status (28)

Country Link
US (2) US20040147603A1 (xx)
EP (1) EP1370513B1 (xx)
JP (1) JP4078206B2 (xx)
KR (2) KR100859609B1 (xx)
CN (1) CN1216034C (xx)
AT (1) ATE294154T1 (xx)
AU (1) AU2002238534C1 (xx)
BR (1) BR0207077A (xx)
CA (1) CA2437592A1 (xx)
CZ (1) CZ20032132A3 (xx)
DE (1) DE60203890T2 (xx)
DK (1) DK1370513T3 (xx)
EC (1) ECSP034713A (xx)
ES (1) ES2240698T3 (xx)
GB (1) GB0103046D0 (xx)
HK (1) HK1060876A1 (xx)
HU (1) HUP0303174A3 (xx)
IL (2) IL157241A0 (xx)
MX (1) MXPA03007072A (xx)
NO (1) NO20033473L (xx)
NZ (1) NZ527300A (xx)
PL (1) PL204812B1 (xx)
PT (1) PT1370513E (xx)
RU (1) RU2289570C2 (xx)
SI (1) SI1370513T1 (xx)
SK (1) SK9992003A3 (xx)
WO (1) WO2002070455A1 (xx)
ZA (1) ZA200306029B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003244633A1 (en) * 2002-07-02 2004-01-23 Novartis Ag Methods for the treatment of sinusitis
GB0503942D0 (en) * 2005-02-25 2005-04-06 Novartis Ag Purification process
WO2007104474A1 (en) * 2006-03-10 2007-09-20 Novartis Ag Antifungal compositions comprising (1) a salt of terbinafine with malic acid and (2) malic acid
EP2043604A2 (en) 2006-06-14 2009-04-08 Dr. Reddy's Laboratories Ltd. Topical compositions
CA2995880C (en) 2009-01-16 2021-01-05 Exelixis, Inc. Processes for preparing n-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
CN106106449A (zh) * 2016-06-21 2016-11-16 广西中烟工业有限责任公司 特比萘芬制剂及其在提高烟叶角鲨烯含量中的应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507755A (en) * 1967-10-17 1970-04-21 Bayer Ag Process for the purification of acrylonitrile by distillation with side stream withdrawal and decantation
US4276125A (en) 1979-02-02 1981-06-30 Asahi Kasei Kogyo Kabushiki Kaisha Process for purification of crude olefinically unsaturated nitrile and condenser useful for same process
US4269667A (en) 1979-08-02 1981-05-26 Standard Oil Company Acrylonitrile purification by extractive distillation
DE19375084I2 (de) * 1979-08-22 2000-11-16 Novartis Ag Propenylamine Verfahren zu ihrer Herstellung sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung als Arzneimittel
KR850001603B1 (ko) 1980-12-03 1985-10-24 아사히 가세이 고오교오 가부시기가이샤 불포화 니트릴의 제조법
GB8608335D0 (en) 1986-04-04 1986-05-08 Pfizer Ltd Pharmaceutically acceptable salts
NZ227042A (en) * 1987-11-27 1991-05-28 Banyu Pharma Co Ltd Substituted alkylamine derivatives and pharmaceutical compositions
HU223343B1 (hu) * 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
US6005001A (en) * 1991-05-20 1999-12-21 Novartis Ag (Formerly Sandoz Ag) Pharmaceutical composition
HU219480B (hu) 1991-05-23 2001-04-28 Novartis Ag. Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására
US5461068A (en) * 1993-09-29 1995-10-24 Corwood Laboratories, Inc. Imidazole derivative tincture and method of manufacture
DE4400770C1 (de) * 1994-01-13 1995-02-02 Lohmann Therapie Syst Lts Wirkstoffhaltiges Pflaster zur Abgabe von Estradiol mit mindestens einem Penetrationsverstärker, Verfahren zu seiner Herstellung und seine Verwendung
NZ280065A (en) * 1995-09-20 1998-04-27 Apotex Inc Preparation of n-alkyl-n-(1-naphthylmethyl)alk-2-en-4-ynylamine derivatives
HUP0001739A3 (en) * 1997-03-31 2001-04-28 Johnson & Johnson Consumer Solvent system for enhanced penetration of pharmaceutical compounds for topical use and the use of the buffer solvent system
US6231875B1 (en) 1998-03-31 2001-05-15 Johnson & Johnson Consumer Companies, Inc. Acidified composition for topical treatment of nail and skin conditions
AU3212099A (en) 1998-03-31 1999-10-18 Johnson & Johnson Consumer Companies, Inc. Method for increasing the permeability of horny human tissue
CN1205922C (zh) * 1998-07-24 2005-06-15 柳署弘 制备含有胆汁酸的澄清水溶液剂型
JP2000053681A (ja) 1998-08-10 2000-02-22 Sankyo Co Ltd 三環性複素環化合物を含有する抗菌剤
DE69909848T2 (de) 1999-10-22 2004-04-15 Richter Gedeon Vegyészeti Gyár R.T. Verfahren zur herstellung substituierter allylamin derivative und deren salze
GB0014448D0 (en) 2000-06-13 2000-08-09 Novartis Ag Organic compounds
JP4899139B2 (ja) 2000-08-10 2012-03-21 株式会社ポーラファルマ 抗真菌医薬組成物
JP4803511B2 (ja) 2000-08-25 2011-10-26 株式会社ポーラファルマ 抗真菌医薬組成物
JP2002068975A (ja) 2000-08-25 2002-03-08 Pola Chem Ind Inc 抗真菌医薬組成物

Also Published As

Publication number Publication date
EP1370513B1 (en) 2005-04-27
AU2002238534B2 (en) 2005-09-29
KR20080041756A (ko) 2008-05-13
DE60203890D1 (de) 2005-06-02
CN1216034C (zh) 2005-08-24
KR20030077606A (ko) 2003-10-01
ATE294154T1 (de) 2005-05-15
ZA200306029B (en) 2004-06-28
PL204812B1 (pl) 2010-02-26
HK1060876A1 (en) 2004-08-27
JP4078206B2 (ja) 2008-04-23
IL157241A (en) 2009-06-15
US20040147603A1 (en) 2004-07-29
CA2437592A1 (en) 2002-09-12
GB0103046D0 (en) 2001-03-21
EP1370513A1 (en) 2003-12-17
AU2002238534C1 (en) 2006-04-13
US7488759B2 (en) 2009-02-10
DE60203890T2 (de) 2006-01-19
PT1370513E (pt) 2005-08-31
MXPA03007072A (es) 2003-11-18
NO20033473D0 (no) 2003-08-05
HUP0303174A2 (hu) 2003-12-29
CZ20032132A3 (cs) 2003-10-15
KR100859609B1 (ko) 2008-09-23
US20070088084A1 (en) 2007-04-19
JP2004523567A (ja) 2004-08-05
PL362554A1 (en) 2004-11-02
SK9992003A3 (en) 2004-01-08
DK1370513T3 (da) 2005-08-01
ECSP034713A (es) 2003-09-24
CN1491206A (zh) 2004-04-21
HUP0303174A3 (en) 2008-03-28
BR0207077A (pt) 2004-01-20
SI1370513T1 (en) 2005-10-31
WO2002070455A1 (en) 2002-09-12
NO20033473L (no) 2003-09-17
ES2240698T3 (es) 2005-10-16
NZ527300A (en) 2005-02-25
RU2003126176A (ru) 2005-03-10
RU2289570C2 (ru) 2006-12-20

Similar Documents

Publication Publication Date Title
AU2002319814A1 (en) Substituted 1h-dihydropyrazoles, their preparation and use
AP1614A (en) New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents.
TW200621737A (en) 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof
DE602004021472D1 (en) Pyrimiidinverbindungen
HK1068626A1 (en) Chemical compounds
AU2003228770A8 (en) Substituted pyrazolopyrimidines
MXPA05009682A (es) Metodos de radiofluorinacion de vectores biologicamente activos.
HK1048990A1 (en) Novel compounds.
IL171992A0 (en) Storage-stable fluorescent whitener formulations
DE60112330D1 (en) Pyrazolopyridinderivate
MY153763A (en) Quinazolinedione derivatives, preparation thereof and therapeutic uses thereof
TW200640911A (en) Novel, long acting betamimetics for the treatment of respiratory diseases
TW200744612A (en) New combination
UA93529C2 (ru) Соли и смеси 9-оксоакридин-10-уксусной кислоты c 1-алкиламино-1-дезоксиполиолами
HK1060876A1 (en) Malic acid addition salts of terbinafine.
TW200720273A (en) Pharmaceutically active spiro-benzimidazoles
WO2006023586A3 (en) Guanylhydrazone compounds, compositions, methods of making and using
DE60201074D1 (en) Pyrazolopyridinderivate
MXPA04005988A (es) 3,4-dihidro-1h-isoquinolin-2-il-derivados.
MXPA04005151A (es) Compuestos terapeuticos.
GB0309440D0 (en) Quinolone derivatives
HU0201195D0 (xx)
WO2005123694A3 (en) Quinazolinone compounds for the treatment of cough
MXPA06000995A (es) Amidas novedosas de acido indolil-3-glioxilico sustituidas en el atomo de n, uso de las mismas como medicamento y metodo para la produccion de las mismas.
BR0314567A (pt) N-bromo-2-pirrolidona estável, métodos para prepará-la e seu uso