IL137330A0 - Novel dihydroxyhexanoic acid derivatives - Google Patents

Novel dihydroxyhexanoic acid derivatives

Info

Publication number
IL137330A0
IL137330A0 IL13733099A IL13733099A IL137330A0 IL 137330 A0 IL137330 A0 IL 137330A0 IL 13733099 A IL13733099 A IL 13733099A IL 13733099 A IL13733099 A IL 13733099A IL 137330 A0 IL137330 A0 IL 137330A0
Authority
IL
Israel
Prior art keywords
acid derivatives
dihydroxyhexanoic acid
novel
novel dihydroxyhexanoic
derivatives
Prior art date
Application number
IL13733099A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of IL137330A0 publication Critical patent/IL137330A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/08Antibacterial agents for leprosy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • AIDS & HIV (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
IL13733099A 1998-02-05 1999-01-18 Novel dihydroxyhexanoic acid derivatives IL137330A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7380198P 1998-02-05 1998-02-05
PCT/IB1999/000067 WO1999040061A2 (fr) 1998-02-05 1999-01-18 Nouveaux derives d'acide dihydroxyhexanoique

Publications (1)

Publication Number Publication Date
IL137330A0 true IL137330A0 (en) 2001-07-24

Family

ID=22115885

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13733099A IL137330A0 (en) 1998-02-05 1999-01-18 Novel dihydroxyhexanoic acid derivatives

Country Status (37)

Country Link
EP (1) EP1051405B1 (fr)
JP (1) JP3693916B2 (fr)
KR (1) KR100385529B1 (fr)
CN (1) CN1177834C (fr)
AP (1) AP992A (fr)
AR (1) AR016175A1 (fr)
AT (1) ATE337307T1 (fr)
AU (1) AU752407B2 (fr)
BG (1) BG104726A (fr)
BR (1) BR9907655A (fr)
CA (1) CA2320388C (fr)
DE (1) DE69932920T2 (fr)
DZ (1) DZ2717A1 (fr)
EA (1) EA003137B1 (fr)
ES (1) ES2268847T3 (fr)
GT (1) GT199900011A (fr)
HK (1) HK1034969A1 (fr)
HR (1) HRP20000529B1 (fr)
HU (1) HUP0100832A3 (fr)
IL (1) IL137330A0 (fr)
IS (1) IS5562A (fr)
MA (1) MA26603A1 (fr)
MY (1) MY133125A (fr)
NO (1) NO20003965D0 (fr)
NZ (1) NZ505724A (fr)
OA (1) OA11448A (fr)
PA (1) PA8467301A1 (fr)
PE (1) PE20000243A1 (fr)
PL (1) PL342817A1 (fr)
SK (1) SK11262000A3 (fr)
TN (1) TNSN99013A1 (fr)
TR (1) TR200002248T2 (fr)
TW (1) TW470744B (fr)
UA (1) UA57824C2 (fr)
WO (1) WO1999040061A2 (fr)
YU (1) YU47100A (fr)
ZA (1) ZA99873B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002535358A (ja) * 1999-01-29 2002-10-22 ミレニアム・ファーマシューティカルズ・インコーポレイテッド 移植片拒絶反応及び虚血−再灌流障害の予防方法
CZ2002487A3 (cs) * 1999-08-20 2002-06-12 Dow Agrosciences Llc Fungicidní heterocyklické aromatické amidy, prostředky na jejich bázi, způsoby jejich pouľití a přípravy
EP1498417A1 (fr) * 2000-02-04 2005-01-19 Pfizer Products Inc. Amides hétérocycliques
KR20020072304A (ko) 2000-02-04 2002-09-14 화이자 프로덕츠 인코포레이티드 헤테로사이클릭 아미드 유도체
US6740636B2 (en) * 2000-07-31 2004-05-25 Schering Aktiengesellschaft Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
US6746856B2 (en) 2000-08-09 2004-06-08 Pfizer Inc. Microbial conversion of bicyclic heteroaromatic compounds
EP1269994A3 (fr) * 2001-06-22 2003-02-12 Pfizer Products Inc. Compositions Pharmaceutiques comprenant un médicament et un polymère permettant d'améliorer la concentration du médicament
CA2450957A1 (fr) * 2001-06-22 2003-01-03 Pfizer Products Inc. Compositions pharmaceutiques de dispersions de medicaments et de polymeres neutres
WO2003000238A1 (fr) 2001-06-22 2003-01-03 Pfizer Products Inc. Compositions pharmaceutiques de produits d'adsorption de medicament amorphe
DE10152351B4 (de) * 2001-10-18 2005-09-22 Schering Ag Feste Arzneimittelformulierung für ein Piperazinharnstoffderivat
JP2005523262A (ja) 2002-02-01 2005-08-04 ファイザー・プロダクツ・インク 薬物及び親油性ミクロ相形成物質の非晶質分散物の医薬組成物
MXPA04011231A (es) * 2002-05-14 2005-01-25 Pfizer Prod Inc Metodos para fabricar derivados de dihidro-furan-2-ona.
EP1503999A1 (fr) * 2002-05-14 2005-02-09 Pfizer Products Inc. Derives d'acide dihydroxyhexanoique, leurs intermediaires et procedes de preparation correspondants
OA12894A (en) * 2002-08-12 2006-10-13 Pfizer Prod Inc Crystal forms of quinoxaline-2-carboxylic acid [4-carbamoy 1-1-(3-fluorobenzyl)-2,7-dihydroxy-7-met hyl-octyl]-amide.
ES2333318T3 (es) 2002-08-12 2010-02-19 Bend Research, Inc. Composiciones farmaceuticas de medicamentos con estructura semiordenada y de polimero.
US20040097554A1 (en) * 2002-10-30 2004-05-20 Pfizer Inc Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents
US20040087571A1 (en) * 2002-10-30 2004-05-06 Pfizer Inc Methods of using CCR1 antagonists as immunomodulatory agents
JP2007501218A (ja) 2003-08-04 2007-01-25 ファイザー・プロダクツ・インク 非晶質薬物の吸着物および親油性ミクロ相形成物質の医薬組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923864A (en) * 1987-12-15 1990-05-08 Pfizer Inc. Certain heterocyclic-hexanamides useful for treating hypertension
DK0708085T3 (da) * 1994-10-19 2002-11-11 Novartis Ag Antivirale ethere af aspartatproteasesubstrat-isostere
DE19708106A1 (de) * 1997-02-28 1998-09-03 Bosch Gmbh Robert Einrichtung und Verfahren zur Information über Verkehrsstörungen

Also Published As

Publication number Publication date
YU47100A (sh) 2002-11-15
ZA99873B (en) 2000-08-04
KR20010040684A (ko) 2001-05-15
JP3693916B2 (ja) 2005-09-14
TR200002248T2 (tr) 2000-12-21
DE69932920T2 (de) 2007-02-08
AU1778999A (en) 1999-08-23
PL342817A1 (en) 2001-07-02
NO20003965L (fr) 2000-10-03
WO1999040061A2 (fr) 1999-08-12
CN1290255A (zh) 2001-04-04
AU752407B2 (en) 2002-09-19
MY133125A (en) 2007-10-31
BG104726A (en) 2001-04-30
NO20003965D0 (no) 2000-08-04
NZ505724A (en) 2003-02-28
DZ2717A1 (fr) 2003-09-01
HUP0100832A2 (hu) 2002-02-28
OA11448A (en) 2003-11-18
AP9901457A0 (en) 1999-03-31
WO1999040061A3 (fr) 1999-10-21
EP1051405A2 (fr) 2000-11-15
EA200000741A1 (ru) 2001-02-26
HRP20000529A2 (en) 2001-08-31
SK11262000A3 (sk) 2001-01-18
GT199900011A (es) 2000-07-20
PA8467301A1 (es) 2000-05-24
HK1034969A1 (en) 2001-11-09
TNSN99013A1 (fr) 2005-11-10
EA003137B1 (ru) 2003-02-27
HRP20000529B1 (en) 2004-12-31
DE69932920D1 (de) 2006-10-05
MA26603A1 (fr) 2004-12-20
IS5562A (is) 2000-07-14
HUP0100832A3 (en) 2002-03-28
UA57824C2 (uk) 2003-07-15
ATE337307T1 (de) 2006-09-15
CA2320388A1 (fr) 1999-08-12
KR100385529B1 (ko) 2003-05-27
JP2002502839A (ja) 2002-01-29
PE20000243A1 (es) 2000-04-07
BR9907655A (pt) 2000-10-24
AR016175A1 (es) 2001-06-20
EP1051405B1 (fr) 2006-08-23
TW470744B (en) 2002-01-01
CN1177834C (zh) 2004-12-01
CA2320388C (fr) 2005-05-03
AP992A (en) 2001-08-06
ES2268847T3 (es) 2007-03-16

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