BR9907655A - Derivados de ácido di-hidróxi-hexanóico - Google Patents

Derivados de ácido di-hidróxi-hexanóico

Info

Publication number
BR9907655A
BR9907655A BR9907655-1A BR9907655A BR9907655A BR 9907655 A BR9907655 A BR 9907655A BR 9907655 A BR9907655 A BR 9907655A BR 9907655 A BR9907655 A BR 9907655A
Authority
BR
Brazil
Prior art keywords
derivatives
dihydroxyhexanoic acid
dihydroxyhexanoic
acid derivatives
acid
Prior art date
Application number
BR9907655-1A
Other languages
English (en)
Inventor
John Charles Kath
Matthew Frank Brown
Christopher Stanley Poss
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR9907655A publication Critical patent/BR9907655A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

Patente de Invenção: <B>"DERIVADOS DE áCIDO DI-HIDRóXI-HEXANóICO"<D>. Derivados de ácido di-hidróxi-hexanóico da fórmula geral são úteis para tratar inflamações e outros distúrbios imunes.
BR9907655-1A 1998-02-05 1999-01-18 Derivados de ácido di-hidróxi-hexanóico BR9907655A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7380198P 1998-02-05 1998-02-05
PCT/IB1999/000067 WO1999040061A2 (en) 1998-02-05 1999-01-18 Novel dihydroxyhexanoic acid derivatives

Publications (1)

Publication Number Publication Date
BR9907655A true BR9907655A (pt) 2000-10-24

Family

ID=22115885

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9907655-1A BR9907655A (pt) 1998-02-05 1999-01-18 Derivados de ácido di-hidróxi-hexanóico

Country Status (37)

Country Link
EP (1) EP1051405B1 (pt)
JP (1) JP3693916B2 (pt)
KR (1) KR100385529B1 (pt)
CN (1) CN1177834C (pt)
AP (1) AP992A (pt)
AR (1) AR016175A1 (pt)
AT (1) ATE337307T1 (pt)
AU (1) AU752407B2 (pt)
BG (1) BG104726A (pt)
BR (1) BR9907655A (pt)
CA (1) CA2320388C (pt)
DE (1) DE69932920T2 (pt)
DZ (1) DZ2717A1 (pt)
EA (1) EA003137B1 (pt)
ES (1) ES2268847T3 (pt)
GT (1) GT199900011A (pt)
HK (1) HK1034969A1 (pt)
HR (1) HRP20000529B1 (pt)
HU (1) HUP0100832A3 (pt)
IL (1) IL137330A0 (pt)
IS (1) IS5562A (pt)
MA (1) MA26603A1 (pt)
MY (1) MY133125A (pt)
NO (1) NO20003965D0 (pt)
NZ (1) NZ505724A (pt)
OA (1) OA11448A (pt)
PA (1) PA8467301A1 (pt)
PE (1) PE20000243A1 (pt)
PL (1) PL342817A1 (pt)
SK (1) SK11262000A3 (pt)
TN (1) TNSN99013A1 (pt)
TR (1) TR200002248T2 (pt)
TW (1) TW470744B (pt)
UA (1) UA57824C2 (pt)
WO (1) WO1999040061A2 (pt)
YU (1) YU47100A (pt)
ZA (1) ZA99873B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1152752A1 (en) * 1999-01-29 2001-11-14 Millennium Pharmaceuticals, Inc. Methods for preventing graft rejection and ischemia-reperfusion injury
EP1204643B1 (en) * 1999-08-20 2008-06-04 Dow AgroSciences LLC Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
EP1498417A1 (en) * 2000-02-04 2005-01-19 Pfizer Products Inc. Heterocyclic amide derivatives
CA2399214A1 (en) 2000-02-04 2001-08-09 Matthew Frank Brown Novel heterocyclic amide derivatives
US6740636B2 (en) 2000-07-31 2004-05-25 Schering Aktiengesellschaft Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
US6746856B2 (en) 2000-08-09 2004-06-08 Pfizer Inc. Microbial conversion of bicyclic heteroaromatic compounds
EA006777B1 (ru) 2001-06-22 2006-04-28 Пфайзер Продактс Инк. Фармацевтические композиции адсорбатов аморфного лекарственного средства
ATE444060T1 (de) 2001-06-22 2009-10-15 Pfizer Prod Inc Pharmazeutische zusammensetzungen enthaltend dispersionen aus arzneistoffen und neutralen polymeren
EP1269994A3 (en) * 2001-06-22 2003-02-12 Pfizer Products Inc. Pharmaceutical compositions comprising drug and concentration-enhancing polymers
DE10152351B4 (de) * 2001-10-18 2005-09-22 Schering Ag Feste Arzneimittelformulierung für ein Piperazinharnstoffderivat
ES2305434T3 (es) 2002-02-01 2008-11-01 Pfizer Products Inc. Composiciones framaceuticas de dispersiones amorfas de farmacos y materiales que forman microfases lipofilas.
CA2484342A1 (en) * 2002-05-14 2003-11-20 Pfizer Products Inc. Methods for manufacture of dihydro-furan-2-one derivatives
BR0309930A (pt) * 2002-05-14 2005-02-09 Pfizer Prod Inc Derivados do ácido dihidroxihexanóico, seus intermediários e métodos de produção
EP1539715A1 (en) * 2002-08-12 2005-06-15 Pfizer Products Inc. Crystal forms of quinoxaline-2-carboxylic acid 4-carbamoyl- 1-(3-fluorobenzyl)-2,7-dihydroxy-7-methyl-octyl -amide
WO2004014342A1 (en) 2002-08-12 2004-02-19 Pfizer Products Inc. Pharmaceutical compositions of semi-ordered drugs and polymers
US20040097554A1 (en) * 2002-10-30 2004-05-20 Pfizer Inc Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents
US20040087571A1 (en) * 2002-10-30 2004-05-06 Pfizer Inc Methods of using CCR1 antagonists as immunomodulatory agents
MXPA06001417A (es) 2003-08-04 2006-05-15 Pfizer Prod Inc Composiciones farmaceuticas de adsorbatos de farmacos amorfos y materiales que forman microfases lipofilas.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923864A (en) * 1987-12-15 1990-05-08 Pfizer Inc. Certain heterocyclic-hexanamides useful for treating hypertension
ATE220661T1 (de) * 1994-10-19 2002-08-15 Novartis Erfind Verwalt Gmbh Antivirale ether von aspartat-protease-substrat- isosteren
DE19708106A1 (de) * 1997-02-28 1998-09-03 Bosch Gmbh Robert Einrichtung und Verfahren zur Information über Verkehrsstörungen

Also Published As

Publication number Publication date
CA2320388A1 (en) 1999-08-12
GT199900011A (es) 2000-07-20
SK11262000A3 (sk) 2001-01-18
JP2002502839A (ja) 2002-01-29
KR20010040684A (ko) 2001-05-15
KR100385529B1 (ko) 2003-05-27
WO1999040061A3 (en) 1999-10-21
CN1177834C (zh) 2004-12-01
IS5562A (is) 2000-07-14
DE69932920D1 (de) 2006-10-05
HRP20000529B1 (en) 2004-12-31
ES2268847T3 (es) 2007-03-16
AU1778999A (en) 1999-08-23
EA003137B1 (ru) 2003-02-27
ZA99873B (en) 2000-08-04
TNSN99013A1 (fr) 2005-11-10
BG104726A (en) 2001-04-30
DZ2717A1 (fr) 2003-09-01
HUP0100832A2 (hu) 2002-02-28
PA8467301A1 (es) 2000-05-24
PE20000243A1 (es) 2000-04-07
EA200000741A1 (ru) 2001-02-26
EP1051405B1 (en) 2006-08-23
UA57824C2 (uk) 2003-07-15
NO20003965L (pt) 2000-10-03
AP9901457A0 (en) 1999-03-31
MY133125A (en) 2007-10-31
AP992A (en) 2001-08-06
JP3693916B2 (ja) 2005-09-14
NZ505724A (en) 2003-02-28
CA2320388C (en) 2005-05-03
AR016175A1 (es) 2001-06-20
TR200002248T2 (tr) 2000-12-21
ATE337307T1 (de) 2006-09-15
DE69932920T2 (de) 2007-02-08
TW470744B (en) 2002-01-01
IL137330A0 (en) 2001-07-24
HUP0100832A3 (en) 2002-03-28
MA26603A1 (fr) 2004-12-20
CN1290255A (zh) 2001-04-04
HK1034969A1 (en) 2001-11-09
WO1999040061A2 (en) 1999-08-12
AU752407B2 (en) 2002-09-19
OA11448A (en) 2003-11-18
YU47100A (sh) 2002-11-15
EP1051405A2 (en) 2000-11-15
HRP20000529A2 (en) 2001-08-31
NO20003965D0 (no) 2000-08-04
PL342817A1 (en) 2001-07-02

Similar Documents

Publication Publication Date Title
BR9907655A (pt) Derivados de ácido di-hidróxi-hexanóico
BR9914044A (pt) ésteres tetrahidropirido
ATE253063T1 (de) 5-ht1f-agonisten
BR9710994A (pt) Derivados anticonvulsivos úteis no tratamento de obesidade.
BR0008922A (pt) Compostos úteis como agentes antiinflamatórios
BR9902086A (pt) Formulações farmacêuticas.
CA2293382A1 (en) Piperazine derivatives and their use as anti-inflammatory agents
RS50091B (sr) Upotreba retigabina u lečenju neuropatskog bola
BR9811099A (pt) Inibidores de urocinase
BR9812371A (pt) Tratamento de distúrbio de conduta
BR9812357A (pt) Tratamento de distúbio oposicional desafiador
DE69432984D1 (de) Therapeutische substituierte guanidine
EA200000165A1 (ru) Разветвленные алкоксизамещенные-2-аминопиридины в качестве ингибиторов nos
AU4179399A (en) Use of nmda antagonists and/or sodium channel antagonists for the treatment of inflammatory disorders
ATE267816T1 (de) Tan-1057 derivate
ID25478A (id) Agonis 5-ht1f
BR0007183A (pt) Isonipectoamidas para o tratamento de distúrbios mediados por integrina
TWI262791B (en) 6-methoxy-2-naphthylacetic acid prodrugs
BR9710992A (pt) Derivados anticovulsivos úteis no tratamento de psorìase
DE60003074D1 (de) Fusidinsäure-derivate
DK1144348T3 (da) LTA4-hydrolaseinhibitorer
BR9803717A (pt) ácidos indol-2-carbocìlicos substituìdos como inibidores de glucosil transferase.
PE61999A1 (es) Compuestos de tetrahidropiridina

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIDO O PEDIDO COM BASE NOS ARTIGOS 8O, 10(VII) E 11 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.