IL128701A0 - 1,2,3,4-Tetrahydro-benzofuro (3,2-c)pyridine derivatives - Google Patents

1,2,3,4-Tetrahydro-benzofuro (3,2-c)pyridine derivatives

Info

Publication number: IL128701A0
Authority: IL; Israel
Prior art keywords: benzofuro; tetrahydro; pyridine derivatives; pyridine; derivatives
Prior art date: 1997-04-08

Application number

IL12870198A

Other languages

English (en)

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-08

Filing date

1998-04-02

Publication date

2000-01-31

1998-04-02 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2000-01-31 Publication of IL128701A0 publication Critical patent/IL128701A0/xx

Links

OGOWMVYFFWEWQT-UHFFFAOYSA-N 1,2,3,4-tetrahydro-[1]benzofuro[3,2-c]pyridine Chemical class O1C2=CC=CC=C2C2=C1CCNC2 OGOWMVYFFWEWQT-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Ophthalmology & Optometry (AREA)
Hematology (AREA)
Obesity (AREA)
Reproductive Health (AREA)
Psychiatry (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Gynecology & Obstetrics (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

IL12870198A 1997-04-08 1998-04-02 1,2,3,4-Tetrahydro-benzofuro (3,2-c)pyridine derivatives IL128701A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97201045		1997-04-08
PCT/EP1998/002136 WO1998045297A1 (en)	1997-04-08	1998-04-02	1,2,3,4-TETRAHYDRO-BENZOFURO[3,2-c]PYRIDINE DERIVATIVES__

Publications (1)

Publication Number	Publication Date
IL128701A0 true IL128701A0 (en)	2000-01-31

Family

ID=8228191

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12870198A IL128701A0 (en)	1997-04-08	1998-04-02	1,2,3,4-Tetrahydro-benzofuro (3,2-c)pyridine derivatives

Country Status (31)

Country	Link
US (1)	US6156757A (uk)
EP (1)	EP1019408B1 (uk)
JP (1)	JP3287577B2 (uk)
KR (1)	KR100315975B1 (uk)
CN (1)	CN1097053C (uk)
AP (1)	AP1138A (uk)
AR (1)	AR012576A1 (uk)
AT (1)	ATE270294T1 (uk)
AU (1)	AU727599B2 (uk)
BG (1)	BG63848B1 (uk)
BR (1)	BR9806263A (uk)
CA (1)	CA2264598C (uk)
CZ (1)	CZ290008B6 (uk)
DE (1)	DE69824872T2 (uk)
EE (1)	EE03691B1 (uk)
ES (1)	ES2224391T3 (uk)
GE (1)	GEP20022823B (uk)
HU (1)	HUP0003624A3 (uk)
ID (1)	ID22131A (uk)
IL (1)	IL128701A0 (uk)
MY (1)	MY120033A (uk)
NO (1)	NO322826B1 (uk)
NZ (1)	NZ334501A (uk)
PL (1)	PL189549B1 (uk)
RU (1)	RU2198175C2 (uk)
SK (1)	SK283621B6 (uk)
TR (1)	TR199900644T2 (uk)
TW (1)	TW589315B (uk)
UA (1)	UA52681C2 (uk)
WO (1)	WO1998045297A1 (uk)
ZA (1)	ZA982969B (uk)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA52681C2 (uk) *	1997-04-08	2003-01-15	Янссен Фармацевтика Н.В.	Похідні 1,2,3,4-тетрагідро-бензофуро[3,2,-c]піридину, спосіб їх одержання та фармацевтична композиція на їх основі
UA70334C2 (en) *	1998-10-06	2004-10-15	Janssen Pharmaceutica N V Jans	BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS
CN1131868C (zh)	1998-10-06	2003-12-24	詹森药业有限公司	作为药物的三环△3－哌啶
ID28967A (id) *	1998-12-21	2001-07-19	Janssen Pharmaceutica Nv	Benzisoksazol dan fenon sebagai alfa 2-antagonis
CA2451606A1 (en)	2001-07-05	2003-01-16	Pharmacia & Upjohn Company	(hetero) aryl substituted benzofurans as 5-ht ligands
CA2480266C (en) *	2002-04-03	2011-07-12	Orion Corporation	Use of an alpha2-adrenoreceptor antagonist for cns-related diseases
MXPA05003607A (es) *	2002-10-04	2005-11-17	Prana Biotechnology Ltd	Compuestos neurologicamente activos.
CN1972938B (zh)	2004-04-12	2010-09-29	大正制药株式会社	环状胺化合物
EP2077262A4 (en) *	2006-10-23	2011-12-28	Takeda Pharmaceutical	IMINOPYRIDINE DERIVATIVES AND THEIR USE
US8481569B2 (en)	2008-04-23	2013-07-09	Takeda Pharmaceutical Company Limited	Iminopyridine derivatives and use thereof
ES2478823T3 (es) *	2008-04-23	2014-07-23	Takeda Pharmaceutical Company Limited	Derivados de iminopiridina y uso de los mismos
US8575186B2 (en) *	2009-10-05	2013-11-05	Albany Molecular Research, Inc.	Epiminocycloalkyl[b] indole derivatives as serotonin sub-type 6 (5-HT6) modulators and uses thereof
EP2668191A4 (en)	2011-01-19	2014-08-20	Albany Molecular Res Inc	BENZOFURO- [3,2-C-] PYRIDINES AND RELATED ANALOGS AS SEROTONIN-SUBTYPE-6 (5-HT6) MODULATORS FOR THE TREATMENT OF ADIPOSITAS, METABOLISM SYNDROME, COGNITION AND SCHIZOPHRENIA
GB201704325D0 (en) *	2017-03-17	2017-05-03	Argonaut Therapeutics Ltd	Compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2570701B1 (fr) *	1984-09-27	1987-05-22	Synthelabo	Derives de furo(3,2-c)pyridines, leur preparation et leur application en therapeutique
US4686226A (en) *	1985-09-03	1987-08-11	Merck & Co., Inc.	Substituted benzo[b]furo- and benzo[b]thieno quinolizines
US4985422A (en) *	1988-04-27	1991-01-15	Glaxo Group Limited	Lactam derivatives
UA52681C2 (uk) *	1997-04-08	2003-01-15	Янссен Фармацевтика Н.В.	Похідні 1,2,3,4-тетрагідро-бензофуро[3,2,-c]піридину, спосіб їх одержання та фармацевтична композиція на їх основі

1998
- 1998-02-04 UA UA99031180A patent/UA52681C2/uk unknown
- 1998-04-02 DE DE69824872T patent/DE69824872T2/de not_active Expired - Lifetime
- 1998-04-02 GE GEAP19985020A patent/GEP20022823B/en unknown
- 1998-04-02 KR KR1019997002086A patent/KR100315975B1/ko not_active IP Right Cessation
- 1998-04-02 PL PL98332382A patent/PL189549B1/pl unknown
- 1998-04-02 WO PCT/EP1998/002136 patent/WO1998045297A1/en active IP Right Grant
- 1998-04-02 EP EP98921458A patent/EP1019408B1/en not_active Expired - Lifetime
- 1998-04-02 BR BR9806263-8A patent/BR9806263A/pt not_active Application Discontinuation
- 1998-04-02 US US09/402,593 patent/US6156757A/en not_active Expired - Lifetime
- 1998-04-02 RU RU99107290/04A patent/RU2198175C2/ru active
- 1998-04-02 ID IDW990147D patent/ID22131A/id unknown
- 1998-04-02 AP APAP/P/1999/001650A patent/AP1138A/en active
- 1998-04-02 EE EEP199900114A patent/EE03691B1/xx not_active IP Right Cessation
- 1998-04-02 HU HU0003624A patent/HUP0003624A3/hu unknown
- 1998-04-02 NZ NZ334501A patent/NZ334501A/en unknown
- 1998-04-02 CN CN98801286A patent/CN1097053C/zh not_active Expired - Lifetime
- 1998-04-02 AT AT98921458T patent/ATE270294T1/de not_active IP Right Cessation
- 1998-04-02 JP JP54240698A patent/JP3287577B2/ja not_active Expired - Fee Related
- 1998-04-02 ES ES98921458T patent/ES2224391T3/es not_active Expired - Lifetime
- 1998-04-02 CZ CZ1999682A patent/CZ290008B6/cs not_active IP Right Cessation
- 1998-04-02 AU AU74307/98A patent/AU727599B2/en not_active Expired
- 1998-04-02 CA CA002264598A patent/CA2264598C/en not_active Expired - Lifetime
- 1998-04-02 IL IL12870198A patent/IL128701A0/xx not_active IP Right Cessation
- 1998-04-02 SK SK287-99A patent/SK283621B6/sk not_active IP Right Cessation
- 1998-04-02 TR TR1999/00644T patent/TR199900644T2/xx unknown
- 1998-04-03 MY MYPI98001502A patent/MY120033A/en unknown
- 1998-04-07 AR ARP980101598A patent/AR012576A1/es active IP Right Grant
- 1998-04-07 ZA ZA9802969A patent/ZA982969B/xx unknown
- 1998-04-07 TW TW087105162A patent/TW589315B/zh not_active IP Right Cessation
1999
- 1999-02-23 NO NO19990859A patent/NO322826B1/no not_active IP Right Cessation
- 1999-02-25 BG BG103213A patent/BG63848B1/bg unknown

Also Published As

Publication number	Publication date
US6156757A (en)	2000-12-05
AP9901650A0 (en)	1999-09-30
PL189549B1 (pl)	2005-08-31
NO322826B1 (no)	2006-12-11
GEP20022823B (en)	2002-10-25
BR9806263A (pt)	2000-04-04
MY120033A (en)	2005-08-30
TR199900644T2 (xx)	2000-09-21
DE69824872D1 (de)	2004-08-05
ID22131A (id)	1999-09-09
JP3287577B2 (ja)	2002-06-04
CN1237179A (zh)	1999-12-01
TW589315B (en)	2004-06-01
CA2264598A1 (en)	1998-10-15
EP1019408B1 (en)	2004-06-30
SK283621B6 (sk)	2003-10-07
ES2224391T3 (es)	2005-03-01
AR012576A1 (es)	2000-11-08
HUP0003624A2 (hu)	2001-04-28
NO990859L (no)	1999-09-30
AP1138A (en)	2003-01-17
AU7430798A (en)	1998-10-30
CN1097053C (zh)	2002-12-25
JP2000505115A (ja)	2000-04-25
WO1998045297A1 (en)	1998-10-15
CA2264598C (en)	2006-10-24
HUP0003624A3 (en)	2002-09-30
BG63848B1 (bg)	2003-03-31
ATE270294T1 (de)	2004-07-15
CZ68299A3 (cs)	2000-08-16
CZ290008B6 (cs)	2002-05-15
NZ334501A (en)	2000-06-23
DE69824872T2 (de)	2005-09-01
KR100315975B1 (ko)	2001-12-22
RU2198175C2 (ru)	2003-02-10
EP1019408A1 (en)	2000-07-19
KR20000036076A (ko)	2000-06-26
PL332382A1 (en)	1999-09-13
BG103213A (en)	2000-05-31
EE03691B1 (et)	2002-04-15
ZA982969B (en)	1999-10-07
AU727599B2 (en)	2000-12-14
UA52681C2 (uk)	2003-01-15
EE9900114A (et)	1999-12-15
NO990859D0 (no)	1999-02-23
SK28799A3 (en)	2001-03-12

Legal Events

Date	Code	Title
2002-12-01	FF	Patent granted
2003-01-12	KB	Patent renewed
2004-06-01	KB	Patent renewed
2008-06-05	KB	Patent renewed
2012-04-30	KB	Patent renewed
2016-03-31	KB	Patent renewed
2018-10-31	EXP	Patent expired

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IL133904A0 (en)	2001-04-30	Pyridine derivatives
IL127566A0 (en)	1999-10-28	Substituted 6,5-hetero- bicyclic derivatives
ZA977652B (en)	1999-02-26	Substituted 6,6-hetero-bicyclic derivatives
PL334847A1 (en)	2000-03-27	Substituted 3-heterocyclyl-benzoyl derivatives
HU9800138D0 (en)	1998-03-30	8-substituted-1,3,8-triaza-spiro [4,5]-decan-4-on derivatives
SI0921125T1 (en)	2002-04-30	1,3,8-Triazaspiro(4,5)decan-4-on derivatives
PL338563A1 (en)	2000-11-06	Substituted derivatives of 1,2,3,4-tetrahydronaphtalene
ZA987688B (en)	1999-02-24	6,9-bridged erythromycin derivatives
ZA9811128B (en)	1999-06-07	1,3,8-Triaza-spiro(4,5)decan-4-on derivatives
IL134996A0 (en)	2001-05-20	6,11-bridged erythromycin derivatives
AP9901650A0 (en)	1999-09-30	1,2, ,4-tetrahydro-benzofuro (3,2-c)pyridine derivatives
IL130377A0 (en)	2000-06-01	Diaza-spiro¬3,5¾nonane derivatives
AU5154699A (en)	2000-03-27	4,5,6,7-tetrahydro-thieno(2,3-c)pyridine derivatives
IL136500A0 (en)	2001-06-14	1,4-diazacycloheptane derivatives
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GB2323842A8 (en)	1998-10-26	Pyridine derivatives
ZA953775B (en)	1996-01-17	8-Amino-pyrido(1,2,3-D,E)(1,3,4) Benzoxadiazine derivatives
AU2610499A (en)	1999-09-20	4,5,6,7-tetrahydro-thieno(3,2-c)pyridine derivatives
ZA989848B (en)	1999-04-29	6,11-bridged erythromycin derivatives
SI1015467T1 (en)	2004-06-30	6,9-bridged erythromycin derivatives
SI1027361T1 (en)	2004-02-29	6,11-bridged erythromycin derivatives
ZA986137B (en)	1999-01-22	Pyridine derivatives
IL132162A0 (en)	2001-03-19	2, 3-Epoxypropionamide derivatives
IL132162A (en)	2000-08-13	2,3-epoxypropionamide derivatives
HUP9903001A3 (en)	2000-06-28	Substituted pyrido- or pyrimido-containing 6,6- or 6,7-bicyclic derivatives