IL127216A0 - Antibodies to the ed-b domain of fibronectin their construction and uses - Google Patents

Antibodies to the ed-b domain of fibronectin their construction and uses

Info

Publication number
IL127216A0
IL127216A0 IL12721697A IL12721697A IL127216A0 IL 127216 A0 IL127216 A0 IL 127216A0 IL 12721697 A IL12721697 A IL 12721697A IL 12721697 A IL12721697 A IL 12721697A IL 127216 A0 IL127216 A0 IL 127216A0
Authority
IL
Israel
Prior art keywords
fibronectin
domain
antibodies
construction
specific
Prior art date
Application number
IL12721697A
Other languages
English (en)
Original Assignee
Philogen Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philogen Srl filed Critical Philogen Srl
Publication of IL127216A0 publication Critical patent/IL127216A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
IL12721697A 1996-05-24 1997-05-23 Antibodies to the ed-b domain of fibronectin their construction and uses IL127216A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9610967A GB9610967D0 (en) 1996-05-24 1996-05-24 Specific binding members,materials and methods
PCT/GB1997/001412 WO1997045544A1 (en) 1996-05-24 1997-05-23 Antibodies to the ed-b domain of fibronectin, their construction and uses

Publications (1)

Publication Number Publication Date
IL127216A0 true IL127216A0 (en) 1999-09-22

Family

ID=10794298

Family Applications (2)

Application Number Title Priority Date Filing Date
IL12721697A IL127216A0 (en) 1996-05-24 1997-05-23 Antibodies to the ed-b domain of fibronectin their construction and uses
IL127216A IL127216A (en) 1996-05-24 1998-11-23 Antibody-specific antibody or fragment - Fibronectin B – ED embryos, process for their preparation and use

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL127216A IL127216A (en) 1996-05-24 1998-11-23 Antibody-specific antibody or fragment - Fibronectin B – ED embryos, process for their preparation and use

Country Status (29)

Country Link
US (3) US7273924B1 (ko)
EP (1) EP0906426B1 (ko)
JP (2) JP4750912B2 (ko)
KR (2) KR100741452B1 (ko)
CN (1) CN100447159C (ko)
AT (1) ATE361364T1 (ko)
AU (1) AU729081B2 (ko)
BG (1) BG65138B1 (ko)
BR (1) BR9709350B1 (ko)
CA (1) CA2256308C (ko)
CZ (1) CZ295531B6 (ko)
DE (1) DE69737683T2 (ko)
DK (1) DK0906426T3 (ko)
EA (1) EA004329B1 (ko)
ES (1) ES2286831T3 (ko)
GB (1) GB9610967D0 (ko)
HK (1) HK1020990A1 (ko)
HU (1) HUP0200546A2 (ko)
IL (2) IL127216A0 (ko)
IS (1) IS2508B (ko)
NO (1) NO324904B1 (ko)
NZ (1) NZ333083A (ko)
PL (1) PL188557B1 (ko)
PT (1) PT906426E (ko)
SI (1) SI0906426T1 (ko)
SK (1) SK285916B6 (ko)
TR (1) TR199802416T2 (ko)
UA (1) UA74129C2 (ko)
WO (1) WO1997045544A1 (ko)

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IT1317108B1 (it) * 2000-12-06 2003-05-26 Philogen Srl Processo per la selezione di frammenti anticorporali anti-angiogenesi,frammenti anticorpali anti-angiogenesi cosi' ottenuti e loro uso.
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WO2012172055A1 (en) 2011-06-15 2012-12-20 Scil Proteins Gmbh Dimeric binding proteins based on modified ubiquitins
WO2012171541A1 (en) 2011-06-15 2012-12-20 Scil Proteins Gmbh Human fusion proteins comprising interferons and hetero-dimeric modified ubiquitin proteins
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WO2014094799A1 (en) 2012-12-19 2014-06-26 Scil-Proteins-Gmbh Ubiquitin moieties as a means for prolonging serum half-life
WO2014194784A1 (zh) * 2013-06-06 2014-12-11 合肥立方制药股份有限公司 人源抗纤连蛋白ed-b结构域的抗体及其用途
WO2016124702A1 (en) 2015-02-06 2016-08-11 Scil Proteins Gmbh Novel egfr binding proteins
PL3322721T3 (pl) 2015-07-16 2022-06-06 Navigo Proteins Gmbh Nowe białka wiążące immunoglobulinę i ich zastosowanie w oczyszczaniu na bazie powinowactwa
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WO2017084017A1 (zh) * 2015-11-16 2017-05-26 合肥立方制药股份有限公司 Ed-b蛋白在诊断组织增生中的应用
EP3452097A1 (en) 2016-05-04 2019-03-13 Navigo Proteins GmbH Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker
KR102578256B1 (ko) 2016-08-11 2023-09-15 리플리겐 코포레이션 친화성 크로마토그래피를 위한 알칼리 안정 fc-결합 단백질
KR102338660B1 (ko) 2016-10-17 2021-12-10 화이자 인코포레이티드 항-edb 항체 및 항체-약물 접합체
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EP3689903A4 (en) 2017-09-30 2022-01-12 Hefei Lifeon Pharmaceutical Co. Ltd. FIBRONECTIN B DOMAIN BINDING PROTEIN
US11414466B2 (en) 2017-11-07 2022-08-16 Navigo Proteins Gmbh Fusion proteins with specificity for ED-B and long serum half-life for diagnosis or treatment of cancer
WO2020070150A1 (en) 2018-10-02 2020-04-09 Philogen S.P.A Il2 immunoconjugates
EP3660039A1 (en) 2018-11-30 2020-06-03 Philogen S.p.A. Il2 immunoconjugates
BR112022002540A2 (pt) 2019-08-15 2022-06-14 Janssen Biotech Inc Materiais e métodos para fragmentos variáveis de cadeia única aprimorados
CN115087670A (zh) 2019-12-11 2022-09-20 西拉格国际有限责任公司 包含ltbr和edb结合结构域的多特异性结合分子及其用途
CN111171149B (zh) * 2020-02-23 2021-09-07 北京康普美特创新医药科技有限责任公司 一种抗补体c5分子的人源化单链抗体及其应用
CN111234016B (zh) * 2020-02-23 2021-09-07 北京康普美特创新医药科技有限责任公司 一种抗补体c5分子的全人源单克隆抗体及应用
KR102614063B1 (ko) 2020-12-24 2023-12-19 대화제약 주식회사 엑스트라도메인 b 피브로넥틴에 특이적으로 결합하는 신규한 항체
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Also Published As

Publication number Publication date
CN100447159C (zh) 2008-12-31
JP4750912B2 (ja) 2011-08-17
NO985459D0 (no) 1998-11-23
AU2910197A (en) 1998-01-05
HUP0200546A2 (en) 2002-07-29
KR20060035812A (ko) 2006-04-26
KR20050010081A (ko) 2005-01-26
US8703143B2 (en) 2014-04-22
CN1219968A (zh) 1999-06-16
BG65138B1 (bg) 2007-03-30
DK0906426T3 (da) 2007-09-10
EP0906426B1 (en) 2007-05-02
TR199802416T2 (xx) 1999-02-22
CZ295531B6 (cs) 2005-08-17
ATE361364T1 (de) 2007-05-15
ES2286831T3 (es) 2007-12-01
EA004329B1 (ru) 2004-04-29
NZ333083A (en) 2000-05-26
KR100741452B1 (ko) 2007-07-20
AU729081B2 (en) 2001-01-25
GB9610967D0 (en) 1996-07-31
UA74129C2 (uk) 2005-11-15
CA2256308A1 (en) 1997-12-04
US20080274099A1 (en) 2008-11-06
US20140134182A1 (en) 2014-05-15
IL127216A (en) 2008-11-26
EP0906426A1 (en) 1999-04-07
BR9709350A (pt) 2000-01-04
IS2508B (is) 2009-04-15
CZ381598A3 (cs) 1999-03-17
SI0906426T1 (sl) 2007-10-31
PL188557B1 (pl) 2005-02-28
DE69737683T2 (de) 2008-01-10
BG102950A (en) 1999-08-31
JP2009050261A (ja) 2009-03-12
EA199801043A1 (ru) 1999-04-29
HK1020990A1 (en) 2000-05-26
DE69737683D1 (de) 2007-06-14
NO985459L (no) 1999-01-22
US7273924B1 (en) 2007-09-25
IS4883A (is) 1998-10-29
SK285916B6 (sk) 2007-11-02
PT906426E (pt) 2007-07-23
JP2000511416A (ja) 2000-09-05
WO1997045544A1 (en) 1997-12-04
PL330075A1 (en) 1999-04-26
CA2256308C (en) 2012-03-13
NO324904B1 (no) 2007-12-27
BR9709350B1 (pt) 2010-12-14
US9096670B2 (en) 2015-08-04
SK161298A3 (en) 1999-07-12

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