IL110628A - Dextrorotatory isomers of phenoxyphenyl compounds Cyclopanthanyl hydroxyureas and pharmaceutical preparations containing them - Google Patents

Dextrorotatory isomers of phenoxyphenyl compounds Cyclopanthanyl hydroxyureas and pharmaceutical preparations containing them

Info

Publication number
IL110628A
IL110628A IL11062894A IL11062894A IL110628A IL 110628 A IL110628 A IL 110628A IL 11062894 A IL11062894 A IL 11062894A IL 11062894 A IL11062894 A IL 11062894A IL 110628 A IL110628 A IL 110628A
Authority
IL
Israel
Prior art keywords
compounds
compound according
formula
medicament
cyclopenten
Prior art date
Application number
IL11062894A
Other languages
English (en)
Hebrew (he)
Other versions
IL110628A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL110628A0 publication Critical patent/IL110628A0/xx
Publication of IL110628A publication Critical patent/IL110628A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
IL11062894A 1993-08-19 1994-08-11 Dextrorotatory isomers of phenoxyphenyl compounds Cyclopanthanyl hydroxyureas and pharmaceutical preparations containing them IL110628A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20545393 1993-08-19

Publications (2)

Publication Number Publication Date
IL110628A0 IL110628A0 (en) 1994-11-11
IL110628A true IL110628A (en) 1998-12-27

Family

ID=16507136

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11062894A IL110628A (en) 1993-08-19 1994-08-11 Dextrorotatory isomers of phenoxyphenyl compounds Cyclopanthanyl hydroxyureas and pharmaceutical preparations containing them

Country Status (27)

Country Link
US (1) US5792882A (es)
EP (1) EP0720598B1 (es)
JP (1) JP2794343B2 (es)
KR (1) KR0170623B1 (es)
CN (1) CN1077568C (es)
AT (1) ATE171939T1 (es)
AU (1) AU674776B2 (es)
BR (1) BR9407314A (es)
CA (1) CA2169066C (es)
CO (1) CO4230229A1 (es)
CZ (1) CZ288358B6 (es)
DE (1) DE69413831T2 (es)
DK (1) DK0720598T3 (es)
EC (1) ECSP941144A (es)
EG (1) EG20530A (es)
ES (1) ES2121218T3 (es)
FI (1) FI114466B (es)
IL (1) IL110628A (es)
MY (1) MY111140A (es)
NO (1) NO305595B1 (es)
NZ (1) NZ269849A (es)
PE (1) PE57194A1 (es)
PL (1) PL176223B1 (es)
RU (1) RU2125987C1 (es)
TW (2) TW418089B (es)
WO (1) WO1995005360A1 (es)
ZA (1) ZA946253B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9606635A (es) * 1994-06-27 1997-12-31 Cytomed Inc Compuestos y metodos para el tratamiento de desordenes cardiovasculares, inflamatorios e inmunes.
MX9703485A (es) * 1994-11-10 1997-08-30 Pfizer Ariloxicicloalquenil-y ariloxiiminocicloalquenilhidroxiureas.
WO1996016054A1 (en) * 1994-11-18 1996-05-30 Pfizer Pharmaceuticals Inc. Cycloalkenyl-n-hydroxyureas
EP1745774A3 (en) 1997-08-11 2007-04-11 Pfizer Products Inc. Solid pharmaceutical dispersions with enhanced bioavailability
US6121323A (en) * 1997-12-03 2000-09-19 3M Innovative Properties Company Bishydroxyureas
CN101068774B (zh) * 2004-12-02 2011-08-10 株式会社Amorepacific 抑制TNF-α形成的2-环戊烯-1-酮肟衍生物
KR101567571B1 (ko) 2007-12-03 2015-11-11 (주)아모레퍼시픽 2-사이클로펜텐-1-온 옥심 유도체를 유효성분으로 포함하는 슬리밍 화장료 조성물
MY172424A (en) 2009-04-03 2019-11-25 Hoffmann La Roche Propane- i-sulfonic acid {3- (4-chloro-phenyl)-1h-pyrrolo [2, 3-b] pyridine-3-carconyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof
US8512464B2 (en) * 2009-12-02 2013-08-20 3M Innovative Properties Company Functionalized zirconia nanoparticles and high index films made therefrom

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ222168A (en) * 1986-10-20 1991-05-28 Oncogene Science Inc Tumour growth inhibiting protein related to tgf-#b#1 and tgf-#b#2, preparation by genetic engineering methods, antibodies and pharmaceutical compositions
ES2060015T3 (es) * 1989-02-03 1994-11-16 Wellcome Found Derivados arilicos anti-inflamatorios.
US5120752A (en) * 1989-12-28 1992-06-09 Abbott Laboratories Cyclopropyl derivative lipoxygenase inhibitors
GB9025514D0 (en) * 1990-11-23 1991-01-09 Wellcome Found Anti-inflammatory compounds
JP3007138B2 (ja) * 1990-11-27 2000-02-07 ファイザー製薬株式会社 新規なヒドロキサム酸とｎ―ヒドロキシ尿素誘導体およびそれらの組成物
JPH06256285A (ja) * 1990-12-11 1994-09-13 Pfizer Pharmaceut Co Ltd ヒドロキサム酸誘導体およびその用途
JPH05163229A (ja) * 1991-12-13 1993-06-29 Pfizer Pharmaceut Co Ltd 新規なシクロプロピル誘導体
JPH05294921A (ja) * 1992-04-17 1993-11-09 Pfizer Pharmaceut Co Ltd 新規なフェニル置換シクロアルキル尿素誘導体および組成物

Also Published As

Publication number Publication date
US5792882A (en) 1998-08-11
WO1995005360A1 (en) 1995-02-23
AU674776B2 (en) 1997-01-09
CZ288358B6 (en) 2001-05-16
AU7350994A (en) 1995-03-14
CN1077568C (zh) 2002-01-09
FI114466B (fi) 2004-10-29
TW448144B (en) 2001-08-01
ATE171939T1 (de) 1998-10-15
NO305595B1 (no) 1999-06-28
FI943799A (fi) 1995-02-20
CA2169066C (en) 1999-06-22
IL110628A0 (en) 1994-11-11
NZ269849A (en) 1997-10-24
KR0170623B1 (ko) 1999-03-30
CZ48396A3 (en) 1996-07-17
PL176223B1 (pl) 1999-05-31
TW418089B (en) 2001-01-11
PL313037A1 (en) 1996-05-27
EP0720598B1 (en) 1998-10-07
CN1129440A (zh) 1996-08-21
JPH08511031A (ja) 1996-11-19
KR960703845A (ko) 1996-08-31
BR9407314A (pt) 1996-04-16
EG20530A (en) 1999-07-31
RU2125987C1 (ru) 1999-02-10
FI943799A0 (fi) 1994-08-18
DE69413831T2 (de) 1999-02-25
ES2121218T3 (es) 1998-11-16
ZA946253B (en) 1996-02-19
EP0720598A1 (en) 1996-07-10
JP2794343B2 (ja) 1998-09-03
MY111140A (en) 1999-08-30
CO4230229A1 (es) 1995-10-19
NO960631D0 (no) 1996-02-16
NO960631L (no) 1996-02-16
PE57194A1 (es) 1995-02-07
CA2169066A1 (en) 1995-02-23
DE69413831D1 (de) 1998-11-12
ECSP941144A (es) 1995-02-27
DK0720598T3 (da) 1999-06-21

Similar Documents

Publication Publication Date Title
FI62529B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara etnolaminderivat
JP2564462B2 (ja) 新規アリールアルキル（チオ）アミド化合物
US20080312237A1 (en) Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
EP0720598B1 (en) Phenoxyphenyl cyclopentenyl hydroxyureas
US20230285377A1 (en) Kcnt1 inhibitors and methods of use
HU207843B (en) Process for producing diurea derivatives and pharmaceutical compositions containing them
US11434199B2 (en) Alcohol derivatives as KV7 potassium channel openers
JPH04257571A (ja) ヒドロキサム酸誘導体および組成物
US5665768A (en) Heteroaryl cycloalkenyl hydroxyureas
JPH0641068A (ja) インドリン誘導体およびアレルギー性または炎症性疾患治療用組成物
JP2756732B2 (ja) リポキシゲナーゼ阻害剤としてのフェニルチオフェニルシクロアルケニルヒドロキシ尿素
Liu et al. An efficient synthesis of enantiomerically pure γ-aminobutyric acid (GABA) derivatives
US5798383A (en) Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas
WO1996016054A1 (en) Cycloalkenyl-n-hydroxyureas
JPH0224813B2 (es)
IE61133B1 (en) New compounds
JPH06293726A (ja) フェノキシフェニルシクロブテニルヒドロキシ尿素
JP2009519300A (ja) カルシウムチャネルブロッカーとしてのジベンゼン誘導体

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees