FI114466B - Menetelmä terapeuttisesti käyttökelpoisten fenoksifenyylisyklopentenyylihydroksiureayhdisteiden valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten fenoksifenyylisyklopentenyylihydroksiureayhdisteiden valmistamiseksi Download PDF

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Publication number
FI114466B
FI114466B FI943799A FI943799A FI114466B FI 114466 B FI114466 B FI 114466B FI 943799 A FI943799 A FI 943799A FI 943799 A FI943799 A FI 943799A FI 114466 B FI114466 B FI 114466B
Authority
FI
Finland
Prior art keywords
compounds
formula
hydroxyurea
phenyl
cyclopenten
Prior art date
Application number
FI943799A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI943799A (fi
FI943799A0 (fi
Inventor
Akiyoshi Kawai
Rodney W Stevens
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI943799A0 publication Critical patent/FI943799A0/fi
Publication of FI943799A publication Critical patent/FI943799A/fi
Application granted granted Critical
Publication of FI114466B publication Critical patent/FI114466B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
FI943799A 1993-08-19 1994-08-18 Menetelmä terapeuttisesti käyttökelpoisten fenoksifenyylisyklopentenyylihydroksiureayhdisteiden valmistamiseksi FI114466B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20545393 1993-08-19
JP20545393 1993-08-19

Publications (3)

Publication Number Publication Date
FI943799A0 FI943799A0 (fi) 1994-08-18
FI943799A FI943799A (fi) 1995-02-20
FI114466B true FI114466B (fi) 2004-10-29

Family

ID=16507136

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943799A FI114466B (fi) 1993-08-19 1994-08-18 Menetelmä terapeuttisesti käyttökelpoisten fenoksifenyylisyklopentenyylihydroksiureayhdisteiden valmistamiseksi

Country Status (27)

Country Link
US (1) US5792882A (es)
EP (1) EP0720598B1 (es)
JP (1) JP2794343B2 (es)
KR (1) KR0170623B1 (es)
CN (1) CN1077568C (es)
AT (1) ATE171939T1 (es)
AU (1) AU674776B2 (es)
BR (1) BR9407314A (es)
CA (1) CA2169066C (es)
CO (1) CO4230229A1 (es)
CZ (1) CZ288358B6 (es)
DE (1) DE69413831T2 (es)
DK (1) DK0720598T3 (es)
EC (1) ECSP941144A (es)
EG (1) EG20530A (es)
ES (1) ES2121218T3 (es)
FI (1) FI114466B (es)
IL (1) IL110628A (es)
MY (1) MY111140A (es)
NO (1) NO305595B1 (es)
NZ (1) NZ269849A (es)
PE (1) PE57194A1 (es)
PL (1) PL176223B1 (es)
RU (1) RU2125987C1 (es)
TW (2) TW418089B (es)
WO (1) WO1995005360A1 (es)
ZA (1) ZA946253B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9606635A (es) * 1994-06-27 1997-12-31 Cytomed Inc Compuestos y metodos para el tratamiento de desordenes cardiovasculares, inflamatorios e inmunes.
MX9703485A (es) * 1994-11-10 1997-08-30 Pfizer Ariloxicicloalquenil-y ariloxiiminocicloalquenilhidroxiureas.
WO1996016054A1 (en) * 1994-11-18 1996-05-30 Pfizer Pharmaceuticals Inc. Cycloalkenyl-n-hydroxyureas
EP1745774A3 (en) 1997-08-11 2007-04-11 Pfizer Products Inc. Solid pharmaceutical dispersions with enhanced bioavailability
US6121323A (en) * 1997-12-03 2000-09-19 3M Innovative Properties Company Bishydroxyureas
CN101068774B (zh) * 2004-12-02 2011-08-10 株式会社Amorepacific 抑制TNF-α形成的2-环戊烯-1-酮肟衍生物
KR101567571B1 (ko) 2007-12-03 2015-11-11 (주)아모레퍼시픽 2-사이클로펜텐-1-온 옥심 유도체를 유효성분으로 포함하는 슬리밍 화장료 조성물
MY172424A (en) 2009-04-03 2019-11-25 Hoffmann La Roche Propane- i-sulfonic acid {3- (4-chloro-phenyl)-1h-pyrrolo [2, 3-b] pyridine-3-carconyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof
US8512464B2 (en) * 2009-12-02 2013-08-20 3M Innovative Properties Company Functionalized zirconia nanoparticles and high index films made therefrom

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ222168A (en) * 1986-10-20 1991-05-28 Oncogene Science Inc Tumour growth inhibiting protein related to tgf-#b#1 and tgf-#b#2, preparation by genetic engineering methods, antibodies and pharmaceutical compositions
ES2060015T3 (es) * 1989-02-03 1994-11-16 Wellcome Found Derivados arilicos anti-inflamatorios.
US5120752A (en) * 1989-12-28 1992-06-09 Abbott Laboratories Cyclopropyl derivative lipoxygenase inhibitors
GB9025514D0 (en) * 1990-11-23 1991-01-09 Wellcome Found Anti-inflammatory compounds
JP3007138B2 (ja) * 1990-11-27 2000-02-07 ファイザー製薬株式会社 新規なヒドロキサム酸とｎ―ヒドロキシ尿素誘導体およびそれらの組成物
JPH06256285A (ja) * 1990-12-11 1994-09-13 Pfizer Pharmaceut Co Ltd ヒドロキサム酸誘導体およびその用途
JPH05163229A (ja) * 1991-12-13 1993-06-29 Pfizer Pharmaceut Co Ltd 新規なシクロプロピル誘導体
JPH05294921A (ja) * 1992-04-17 1993-11-09 Pfizer Pharmaceut Co Ltd 新規なフェニル置換シクロアルキル尿素誘導体および組成物

Also Published As

Publication number Publication date
US5792882A (en) 1998-08-11
WO1995005360A1 (en) 1995-02-23
AU674776B2 (en) 1997-01-09
CZ288358B6 (en) 2001-05-16
AU7350994A (en) 1995-03-14
CN1077568C (zh) 2002-01-09
TW448144B (en) 2001-08-01
ATE171939T1 (de) 1998-10-15
NO305595B1 (no) 1999-06-28
FI943799A (fi) 1995-02-20
CA2169066C (en) 1999-06-22
IL110628A0 (en) 1994-11-11
NZ269849A (en) 1997-10-24
KR0170623B1 (ko) 1999-03-30
CZ48396A3 (en) 1996-07-17
PL176223B1 (pl) 1999-05-31
TW418089B (en) 2001-01-11
PL313037A1 (en) 1996-05-27
EP0720598B1 (en) 1998-10-07
CN1129440A (zh) 1996-08-21
JPH08511031A (ja) 1996-11-19
KR960703845A (ko) 1996-08-31
BR9407314A (pt) 1996-04-16
EG20530A (en) 1999-07-31
RU2125987C1 (ru) 1999-02-10
FI943799A0 (fi) 1994-08-18
DE69413831T2 (de) 1999-02-25
ES2121218T3 (es) 1998-11-16
ZA946253B (en) 1996-02-19
EP0720598A1 (en) 1996-07-10
JP2794343B2 (ja) 1998-09-03
MY111140A (en) 1999-08-30
CO4230229A1 (es) 1995-10-19
NO960631D0 (no) 1996-02-16
NO960631L (no) 1996-02-16
PE57194A1 (es) 1995-02-07
CA2169066A1 (en) 1995-02-23
IL110628A (en) 1998-12-27
DE69413831D1 (de) 1998-11-12
ECSP941144A (es) 1995-02-27
DK0720598T3 (da) 1999-06-21

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