ID29236A - Benzopiran-benzopiran dan benzoksepin-benzoksepin, komposisi-komposisi famaseutikal yang mengandungnya, dan proses penyiapannya - Google Patents

Benzopiran-benzopiran dan benzoksepin-benzoksepin, komposisi-komposisi famaseutikal yang mengandungnya, dan proses penyiapannya

Info

Publication number
ID29236A
ID29236A IDW00200101656A ID20011656A ID29236A ID 29236 A ID29236 A ID 29236A ID W00200101656 A IDW00200101656 A ID W00200101656A ID 20011656 A ID20011656 A ID 20011656A ID 29236 A ID29236 A ID 29236A
Authority
ID
Indonesia
Prior art keywords
famaseutical
benzoxins
benzopirans
compositions
beneficial
Prior art date
Application number
IDW00200101656A
Other languages
English (en)
Inventor
Michel Brunet
Jean J Zeiller
Jean J Berthelon
Francis Cintard
Gauy Augert
Daniel Guerrier
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ID29236A publication Critical patent/ID29236A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/06—Peri-condensed systems
IDW00200101656A 1998-12-29 1999-12-20 Benzopiran-benzopiran dan benzoksepin-benzoksepin, komposisi-komposisi famaseutikal yang mengandungnya, dan proses penyiapannya ID29236A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9816574A FR2787789B1 (fr) 1998-12-29 1998-12-29 Benzopyranes et benzoxepines utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparations

Publications (1)

Publication Number Publication Date
ID29236A true ID29236A (id) 2001-08-16

Family

ID=9534619

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW00200101656A ID29236A (id) 1998-12-29 1999-12-20 Benzopiran-benzopiran dan benzoksepin-benzoksepin, komposisi-komposisi famaseutikal yang mengandungnya, dan proses penyiapannya

Country Status (19)

Country Link
US (1) US6596758B1 (id)
EP (1) EP1140893B1 (id)
JP (1) JP4607331B2 (id)
KR (1) KR100684088B1 (id)
CN (2) CN1173967C (id)
AU (1) AU759892B2 (id)
BR (1) BR9916633A (id)
CA (1) CA2356680C (id)
CZ (1) CZ300086B6 (id)
FR (1) FR2787789B1 (id)
HK (1) HK1047584B (id)
HU (1) HUP0104839A3 (id)
ID (1) ID29236A (id)
NO (1) NO20013242L (id)
PL (1) PL196524B1 (id)
RU (1) RU2228333C2 (id)
SK (1) SK9022001A3 (id)
WO (1) WO2000039113A1 (id)
ZA (1) ZA200106177B (id)

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CA2461381A1 (en) * 2001-10-04 2003-04-10 Wyeth Chroman derivatives as 5-hydroxytryptamine-6 ligands
FR2845386B1 (fr) * 2002-10-07 2006-06-30 Merck Sante Sas Nouveaux derives metastables de benzoxepines utilisables dans le traitement des dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparation
JP2006514666A (ja) 2003-02-26 2006-05-11 中国科学院上海薬物研究所 ベンゾピラン系化合物、その製造方法及び用途
NZ546834A (en) * 2003-10-01 2010-03-26 Adolor Corp Spirocyclic heterocyclic derivatives and methods of their use
US6887896B1 (en) * 2003-10-29 2005-05-03 Allergan, Inc. 7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity
SI1535612T1 (sl) * 2003-11-28 2006-12-31 Merck Sante Sas Zdravljenje hiperurikemije
PL1591434T3 (pl) * 2004-04-27 2007-09-28 Merck Sante Sas Nowe 1-metoksy-2-fenylo-etyleny przydatne do otrzymywania 5-karboksyaldehydu-2-3-dihydrobenzoksepin
SI1600446T1 (sl) * 2004-05-18 2008-04-30 Merck Sante Sas Novi derivati 3,3-dimetil-5-ciano-benzoksepina, ki so uporabljivi za pripravo derivatov 5-formil-benzoksepina
ATE518850T1 (de) * 2004-06-25 2011-08-15 Merck Sante Sas 5-alkenon-3,3-dimethyl-benzoxepinderivate und ihre verwendung in der herstellung von antidiabetischen pentadiensäuren
US7235688B1 (en) 2004-11-04 2007-06-26 University Of Notre Dame Du Lac Process for preparing histone deacetylase inhibitors and intermediates thereof
US20070021612A1 (en) * 2004-11-04 2007-01-25 University Of Notre Dame Du Lac Processes and compounds for preparing histone deacetylase inhibitors and intermediates thereof
EP1836183A2 (en) * 2004-12-13 2007-09-26 Galileo Pharmaceuticals, Inc. Spiro derivatives as lipoxygenase inhibitors
KR100752244B1 (ko) * 2005-02-16 2007-08-27 주식회사 엠디바이오알파 비만, 당뇨, 대사성 질환, 퇴행성 질환 및 미토콘드리아이상 질환의 치료 또는 예방을 위한 약제 조성물
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) * 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
WO2008033299A2 (en) * 2006-09-12 2008-03-20 Adolor Corporation Use of n-containing spirocompounds for the enhancement of cognitive function
CN101172978A (zh) * 2006-11-02 2008-05-07 中国人民解放军军事医学科学院毒物药物研究所 六元杂环化合物,其制备方法及其医药用途
AU2008229617A1 (en) * 2007-03-16 2008-09-25 Novogen Research Pty Ltd Method for inducing autophagy
ES2562798T3 (es) * 2008-08-09 2016-03-08 Merck Patent Gmbh Uso de compuestos de indol como cosmético
JP5764060B2 (ja) * 2008-08-12 2015-08-12 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 化粧品としての５−（７−メトキシ−３，３−ジメチル−２，３−ジヒドロ−１−ベンゾオキセピン−５−イル）−３−メチル−ペンタ−２，４−ジエン酸の使用
US10221143B2 (en) 2015-03-03 2019-03-05 Arizona Board Of Regents On Behalf Of Arizona State University Substituted anilines for treatment of animal diseases
US10112917B2 (en) 2015-03-03 2018-10-30 Arizona Board Of Regents On Behalf Of Arizona State University Therapeutic compounds
US10238626B2 (en) 2017-01-23 2019-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Therapeutic compounds
US10231947B2 (en) 2017-01-23 2019-03-19 Arizona Board Of Regents On Behalf Of Arizona State University Isochroman compounds and methods of use thereof
US10238655B2 (en) 2017-01-23 2019-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Dihydroindene and tetrahydronaphthalene compounds
CN108371712B (zh) * 2018-01-18 2020-12-25 华北理工大学 咖啡因与PPARγ激动剂联合制备AD药物中的用途
WO2022053416A1 (en) 2020-09-08 2022-03-17 Merck Patent Gmbh Improvement of water-holding capacity of skin by oxeglitazar

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004744A (en) * 1988-12-13 1991-04-02 Bayer Aktiengesellschaft Pyridazinones as pesticides
EP0412939A3 (en) * 1989-08-11 1991-09-04 Ciba-Geigy Ag Certain benzopyran and benzothiopyran derivatives
US4946860A (en) * 1989-11-03 1990-08-07 Rorer Pharmaceutical Corporation Benzothiopyranyl derivatives as HMG-CoA reductase inhibitors
JP4001618B2 (ja) * 1991-12-18 2007-10-31 ザ ソールク インスチチュート フォア バイオロジカル スタディズ レチノイド受容体によって仲介される過程の修飾方法およびそれに有用な化合物
US5391569A (en) * 1992-09-29 1995-02-21 Adir Et Compagnie New chromene compounds having a triene side chain
EP0800503B1 (en) * 1994-12-30 2000-05-10 Ligand Pharmaceuticals, Inc. Novel trienoic retinoid compounds and methods
US5675033A (en) * 1995-06-06 1997-10-07 Allergan 2,4-pentadienoic acid derivatives having retinoid-like biological activity

Also Published As

Publication number Publication date
US6596758B1 (en) 2003-07-22
JP2003517449A (ja) 2003-05-27
FR2787789B1 (fr) 2002-06-14
NO20013242D0 (no) 2001-06-28
CN1554651A (zh) 2004-12-15
AU759892B2 (en) 2003-05-01
HUP0104839A3 (en) 2003-01-28
HK1047584B (zh) 2005-05-27
ZA200106177B (en) 2002-12-24
PL196524B1 (pl) 2008-01-31
CZ300086B6 (cs) 2009-01-28
CA2356680C (en) 2010-03-23
NO20013242L (no) 2001-06-28
HUP0104839A2 (hu) 2002-04-29
WO2000039113A1 (en) 2000-07-06
CN1173967C (zh) 2004-11-03
CA2356680A1 (en) 2000-07-06
EP1140893A1 (en) 2001-10-10
CZ20012387A3 (cs) 2001-11-14
HK1047584A1 (en) 2003-02-28
PL349448A1 (en) 2002-07-29
KR100684088B1 (ko) 2007-02-16
AU2432900A (en) 2000-07-31
BR9916633A (pt) 2001-09-25
CN1359383A (zh) 2002-07-17
CN1307171C (zh) 2007-03-28
EP1140893B1 (en) 2003-03-05
SK9022001A3 (en) 2002-04-04
JP4607331B2 (ja) 2011-01-05
FR2787789A1 (fr) 2000-06-30
KR20010101339A (ko) 2001-11-14
RU2228333C2 (ru) 2004-05-10

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