KR100752244B1 - 비만, 당뇨, 대사성 질환, 퇴행성 질환 및 미토콘드리아이상 질환의 치료 또는 예방을 위한 약제 조성물 - Google Patents
비만, 당뇨, 대사성 질환, 퇴행성 질환 및 미토콘드리아이상 질환의 치료 또는 예방을 위한 약제 조성물 Download PDFInfo
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- KR100752244B1 KR100752244B1 KR1020060014541A KR20060014541A KR100752244B1 KR 100752244 B1 KR100752244 B1 KR 100752244B1 KR 1020060014541 A KR1020060014541 A KR 1020060014541A KR 20060014541 A KR20060014541 A KR 20060014541A KR 100752244 B1 KR100752244 B1 KR 100752244B1
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Abstract
Description
Claims (9)
- (a) 약리학적 유효량의 하기 화학식 1로 표시되는 화합물, 또는 약제학적으로 허용되는 그것의 염, 및 (b) 약제학적으로 허용되는 담체, 희석제, 또는 부형제, 또는 이들의 조합을 포함하고 있으며, 비만, 비만 합병증, 간질환, 동맥경화, 뇌졸중, 심근경색, 심혈관 질환, 허혈성 질환, 당뇨병, 당뇨병 관련 합병증 및 염증으로 이루어진 군에서 선택되는 질병의 치료를 위한 약제 조성물:상기 식에서,R1 및 R2 는 각각 독립적으로 수소, 할로겐, 알콕시, 히드록시 또는 탄소수 1 ~ 6의 저급알킬이며;R3, R4, R5, R6, R7 및 R8 는 각각 독립적으로 수소, 히드록시, 탄소수 1 ~ 20의 알킬, 알켄 또는 알콕시, 시클로알킬, 헤테로시클로알킬, 아릴 또는 헤테로아릴이고, 또는 이들 중 두 개의 치환기가 상호 결합에 의해 환형 구조를 이룰 수 있으며;n 은 0 또는 1이고, n 이 0인 경우에 그것의 인접 탄소원자들은 직접결합에 의해 환형 구조를 이룬다.
- 제 1 항에 있어서, 상기 R1 및 R2 는 각각 수소인 것을 특징으로 하는 약제 조성물.
- 삭제
- 삭제
- 제 1 항에 있어서, 상기 당뇨병 관련 합병증은 고지혈증, 고혈압, 망막증 또는 신부전증인 것을 특징으로 하는 약제 조성물.
- 삭제
Priority Applications (1)
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KR1020060014541A KR100752244B1 (ko) | 2005-02-16 | 2006-02-15 | 비만, 당뇨, 대사성 질환, 퇴행성 질환 및 미토콘드리아이상 질환의 치료 또는 예방을 위한 약제 조성물 |
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KR20050012625 | 2005-02-16 | ||
KR1020050012625 | 2005-02-16 | ||
KR1020060014541A KR100752244B1 (ko) | 2005-02-16 | 2006-02-15 | 비만, 당뇨, 대사성 질환, 퇴행성 질환 및 미토콘드리아이상 질환의 치료 또는 예방을 위한 약제 조성물 |
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KR1020070064943A Division KR20070074538A (ko) | 2007-06-29 | 2007-06-29 | 비만, 당뇨, 대사성 질환, 퇴행성 질환 및 미토콘드리아이상 질환의 치료 또는 예방을 위한 약제 조성물 |
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KR20060092106A KR20060092106A (ko) | 2006-08-22 |
KR100752244B1 true KR100752244B1 (ko) | 2007-08-27 |
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US (3) | US20080146655A1 (ko) |
EP (4) | EP1848432B1 (ko) |
JP (1) | JP5039565B2 (ko) |
KR (1) | KR100752244B1 (ko) |
CN (1) | CN101119726B (ko) |
AU (1) | AU2006214892B2 (ko) |
BR (1) | BRPI0607860A2 (ko) |
CA (2) | CA2770430A1 (ko) |
EA (1) | EA013214B1 (ko) |
IL (2) | IL184554A0 (ko) |
MX (1) | MX2007009944A (ko) |
NZ (1) | NZ556585A (ko) |
PH (1) | PH12013500419A1 (ko) |
WO (1) | WO2006088315A1 (ko) |
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