ID23304A - Turunan-turunan diaza-spiro [3,5] nonana, proses pembuatan dan penggunaannya - Google Patents

Turunan-turunan diaza-spiro [3,5] nonana, proses pembuatan dan penggunaannya

Info

Publication number
ID23304A
ID23304A IDP990543D ID990543D ID23304A ID 23304 A ID23304 A ID 23304A ID P990543 D IDP990543 D ID P990543D ID 990543 D ID990543 D ID 990543D ID 23304 A ID23304 A ID 23304A
Authority
ID
Indonesia
Prior art keywords
durunan
nonana
diaza
spiro
making
Prior art date
Application number
IDP990543D
Other languages
English (en)
Inventor
Geo Adam
Andrea Cesura
Francois Jenck
Sabine Kolczewski
Stephan Rover
Jurgen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ID23304A publication Critical patent/ID23304A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
IDP990543D 1998-06-12 1999-06-08 Turunan-turunan diaza-spiro [3,5] nonana, proses pembuatan dan penggunaannya ID23304A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98110804 1998-06-12

Publications (1)

Publication Number Publication Date
ID23304A true ID23304A (id) 2000-04-05

Family

ID=8232114

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP990543D ID23304A (id) 1998-06-12 1999-06-08 Turunan-turunan diaza-spiro [3,5] nonana, proses pembuatan dan penggunaannya

Country Status (28)

Country Link
US (1) US6113527A (id)
EP (1) EP0970957B1 (id)
JP (1) JP3286268B2 (id)
KR (1) KR100344732B1 (id)
CN (1) CN1107066C (id)
AR (1) AR019859A1 (id)
AT (1) ATE204279T1 (id)
AU (1) AU743983B2 (id)
BR (1) BR9902651A (id)
CA (1) CA2274202A1 (id)
DE (1) DE69900220T2 (id)
DK (1) DK0970957T3 (id)
ES (1) ES2162503T3 (id)
HR (1) HRP990188A2 (id)
HU (1) HU220894B1 (id)
ID (1) ID23304A (id)
IL (1) IL130377A0 (id)
MA (1) MA26644A1 (id)
NO (1) NO312590B1 (id)
NZ (1) NZ336189A (id)
PE (1) PE20000548A1 (id)
PL (1) PL333695A1 (id)
PT (1) PT970957E (id)
SG (1) SG79259A1 (id)
SI (1) SI0970957T1 (id)
TR (1) TR199901381A2 (id)
YU (1) YU26499A (id)
ZA (1) ZA993852B (id)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005502619A (ja) * 2001-07-02 2005-01-27 オメロス コーポレイション オピオイドレセプター様レセプター1アゴニストと交替でオピオイドレセプターアゴニストを投与することを含む、痛覚脱失を生成するための方法
US20030040479A1 (en) * 2001-07-02 2003-02-27 Omeros Corporation Rotational intrathecal analgesia method and device
US7566728B2 (en) * 2002-03-29 2009-07-28 Mitsubishi Tanabe Pharma Corporation Remedy for sleep disturbance
JP2005289816A (ja) 2002-05-14 2005-10-20 Banyu Pharmaceut Co Ltd ベンズイミダゾール誘導体
ES2355157T3 (es) 2002-07-05 2011-03-23 Targacept, Inc. Compuestos diazaspirocíclico n-arilo y métodos de preparación y uso de las mismas.
US7081463B2 (en) * 2002-09-09 2006-07-25 Janssen Pharmaceutica N.V. Hydroxy alkyl substituted 1,3,8-Triazaspiro[4.5]decan-4-one derivatives useful for the treatment of orl-1receptor mediated disorders
GB0323204D0 (en) * 2003-10-03 2003-11-05 Novartis Ag Organic compounds
US20050228023A1 (en) * 2003-12-19 2005-10-13 Sri International Agonist and antagonist ligands of the nociceptin receptor
US20060178390A1 (en) * 2004-08-02 2006-08-10 Alfonzo Jordan 1,3,8-Triazaspiro[4,5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
CA2575461A1 (en) * 2004-08-20 2006-03-02 Targacept, Inc. The use of n-aryl diazaspiracyclic compounds in the treatment of addiction
US20080247964A1 (en) * 2006-05-08 2008-10-09 Yuelian Xu Substituted azaspiro derivatives
AU2007325355A1 (en) * 2006-11-28 2008-06-05 Janssen Pharmaceutica N.V. Salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl) -1,3,8-triaza-spiro[4.5]decan-4-one
MX2009011006A (es) * 2007-04-09 2009-11-02 Janssen Pharmaceutica Nv Derivados de 1,3,8-trisustituido-1,3,8-triaza-espiro[4.5]decano-4- ona como ligandos del receptor de orl-1 para el tratamiento de ansiedad y depresion.
KR101704226B1 (ko) 2015-06-30 2017-02-07 현대자동차주식회사 자동차의 쿼터글라스 어셈블리
WO2023122662A1 (en) * 2021-12-22 2023-06-29 The Regents Of The University Of California Covalently binding inhibitors of g12s, g12d and/or g12e mutants of k-ras gtpase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756743A (en) * 1996-04-10 1998-05-26 Hoechst Marion Roussel Inc. Spiro cyclopent b!indole-piperidines!

Also Published As

Publication number Publication date
AR019859A1 (es) 2002-03-20
HU220894B1 (en) 2002-06-29
DK0970957T3 (da) 2001-12-03
CN1242366A (zh) 2000-01-26
PT970957E (pt) 2002-02-28
DE69900220D1 (de) 2001-09-20
TR199901381A3 (tr) 2000-01-21
PE20000548A1 (es) 2000-07-15
SG79259A1 (en) 2001-03-20
SI0970957T1 (id) 2001-12-31
NO992873L (no) 1999-12-13
PL333695A1 (en) 1999-12-20
NO992873D0 (no) 1999-06-11
MA26644A1 (fr) 2004-12-20
HUP9901911A1 (hu) 2000-05-28
JP2000053679A (ja) 2000-02-22
AU743983B2 (en) 2002-02-14
KR20000006060A (ko) 2000-01-25
KR100344732B1 (ko) 2002-07-19
TR199901381A2 (xx) 2000-01-21
EP0970957A1 (en) 2000-01-12
ES2162503T3 (es) 2001-12-16
ZA993852B (en) 1999-12-13
EP0970957B1 (en) 2001-08-16
CA2274202A1 (en) 1999-12-12
AU3498799A (en) 1999-12-23
JP3286268B2 (ja) 2002-05-27
YU26499A (sh) 2002-09-19
NO312590B1 (no) 2002-06-03
BR9902651A (pt) 2000-05-16
HRP990188A2 (en) 2000-02-29
US6113527A (en) 2000-09-05
CN1107066C (zh) 2003-04-30
ATE204279T1 (de) 2001-09-15
IL130377A0 (en) 2000-06-01
DE69900220T2 (de) 2002-05-08
NZ336189A (en) 2000-10-27
HU9901911D0 (en) 1999-08-30

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