HUP0401333A3 - Spiropyrazole compounds and pharmaceutical compositions containing them - Google Patents

Spiropyrazole compounds and pharmaceutical compositions containing them

Info

Publication number: HUP0401333A3
Authority: HU; Hungary
Prior art keywords: pharmaceutical compositions; compositions containing; spiropyrazole; compounds; spiropyrazole compounds
Prior art date: 2001-04-18

Application number

HU0401333A

Other languages

English (en)

Original Assignee

Euro Celtique Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-18

Filing date

2002-04-18

Publication date

2004-11-29

2002-04-18 Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa

2004-10-28 Publication of HUP0401333A2 publication Critical patent/HUP0401333A2/hu

2004-11-29 Publication of HUP0401333A3 publication Critical patent/HUP0401333A3/hu

Links

150000001875 compounds Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

HU0401333A 2001-04-18 2002-04-18 Spiropyrazole compounds and pharmaceutical compositions containing them HUP0401333A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US28467501P	2001-04-18	2001-04-18
PCT/US2002/012376 WO2002085355A1 (en)	2001-04-18	2002-04-18	Spiropyrazole compounds

Publications (2)

Publication Number	Publication Date
HUP0401333A2 HUP0401333A2 (hu)	2004-10-28
HUP0401333A3 true HUP0401333A3 (en)	2004-11-29

Family

ID=23091099

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0401333A HUP0401333A3 (en)	2001-04-18	2002-04-18	Spiropyrazole compounds and pharmaceutical compositions containing them

Country Status (28)

Country	Link
US (2)	US6635653B2 (hu)
EP (1)	EP1385515B1 (hu)
JP (1)	JP4342181B2 (hu)
KR (1)	KR100628292B1 (hu)
CN (1)	CN1516584A (hu)
AT (1)	ATE403429T1 (hu)
AU (1)	AU2002311833B2 (hu)
BR (1)	BR0209127A (hu)
CA (1)	CA2444634C (hu)
CY (1)	CY1108454T1 (hu)
CZ (1)	CZ20032849A3 (hu)
DE (1)	DE60228071D1 (hu)
DK (1)	DK1385515T3 (hu)
ES (1)	ES2312584T3 (hu)
HK (1)	HK1062885A1 (hu)
HU (1)	HUP0401333A3 (hu)
IL (2)	IL158485A0 (hu)
MX (1)	MXPA03009604A (hu)
NO (1)	NO20034660L (hu)
NZ (1)	NZ528978A (hu)
PL (1)	PL367263A1 (hu)
PT (1)	PT1385515E (hu)
RU (1)	RU2299883C2 (hu)
SI (1)	SI1385515T1 (hu)
UA (1)	UA74439C2 (hu)
WO (1)	WO2002085355A1 (hu)
YU (1)	YU82403A (hu)
ZA (1)	ZA200308103B (hu)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
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HUP0401333A3 (en) *	2001-04-18	2004-11-29	Euro Celtique Sa	Spiropyrazole compounds and pharmaceutical compositions containing them
DK1491212T3 (da)	2002-03-29	2012-10-29	Mitsubishi Tanabe Pharma Corp	Middel til behandling af søvnforstyrrelser
NZ538307A (en)	2002-09-09	2008-04-30	Janssen Pharmaceutica Nv	Hydroxy alkyl substituted 1,3,8-triazaspiro[4.5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
WO2004034983A2 (en) *	2002-10-17	2004-04-29	Euro-Celtique, S.A.	Preparation of triazospiro compounds
US20040242583A1 (en) *	2003-01-20	2004-12-02	Aventis Pharma Deutschland Gmbh	Pyrimido[5,4-e][1,2,4]triazine-5,7-diones, processes for preparing them and their use
WO2004103305A2 (en) *	2003-05-16	2004-12-02	Euroceltique S.A.	Spiropyrazole compound
WO2005011665A1 (en) *	2003-07-22	2005-02-10	Arakis Ltd.	The use of proglumide for the treatment of emesis
US20110008327A1 (en)	2004-03-29	2011-01-13	Cheng Jin Q	Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
US20100009929A1 (en)	2004-03-29	2010-01-14	Cheng Jin Q	Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
US20100028339A1 (en) *	2004-03-29	2010-02-04	Cheng Jin Q	Compositions including triciribine and trastuzumab and methods of use thereof
MXPA06011219A (es)	2004-03-29	2007-05-08	Univ South Florida	Tratamiento efectivo de tumores y cancer con triciribina y compuestos relacionados.
US20100009928A1 (en)	2004-03-29	2010-01-14	Cheng Jin Q	Compositions including triciribine and taxanes and methods of use thereof
US20100173864A1 (en)	2004-03-29	2010-07-08	Cheng Jin Q	Compositions including triciribine and one or more platinum compounds and methods of use thereof
ES2350647T3 (es)	2005-03-08	2011-01-25	Janssen Pharmaceutica Nv	Derivados de diaza-espiro-[4.4]-nonano como antagonistas de neuroquininas (nk1).
CN1870631B (zh) *	2005-11-11	2010-04-14	华为技术有限公司	媒体网关的门控方法
US20080051380A1 (en)	2006-08-25	2008-02-28	Auerbach Alan H	Methods and compositions for treating cancer
AU2007325355A1 (en)	2006-11-28	2008-06-05	Janssen Pharmaceutica N.V.	Salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl) -1,3,8-triaza-spiro[4.5]decan-4-one
CN101595100B (zh)	2007-01-16	2014-06-11	普渡制药公司	作为orl-1配体的杂环取代的哌啶
US8741916B2 (en)	2007-04-09	2014-06-03	Janssen Pharmaceutica Nv	1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the ORL-1 receptor
EP3564240B1 (en) *	2007-08-31	2022-04-06	Purdue Pharma L.P.	Piperidine intermediates
AU2009275218C1 (en)	2008-07-21	2015-02-05	Purdue Pharma L.P.	Substituted-Quinoxaline-Type Bridged-Piperidine Compounds and the uses thereof
UA107943C2 (en) *	2009-11-16	2015-03-10	Lilly Co Eli	Compounds of spiropiperidines as antagonists of the orl-1 receptors
AU2011346749A1 (en)	2010-12-22	2013-05-02	Purdue Pharma L.P.	Phosphorus-substituted quinoxaline-type piperidine compounds and uses thereof
ES2583146T3 (es)	2011-12-01	2016-09-19	Purdue Pharma L.P.	Compuestos de piperidina de tipo quinoxalina sustituidos con azetidina y usos de éstos
US9085561B2 (en)	2012-07-30	2015-07-21	Purdue Pharma L.P.	Cyclic urea- or lactam-substituted quinoxaline-type piperidines as ORL-1 modulators
WO2014102588A2 (en)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Indole and indoline-type piperidine compounds and uses thereof
US10118927B2 (en)	2012-12-27	2018-11-06	Purdue Pharma L.P.	Substituted piperidin-4-amino-type compounds and uses thereof
WO2014102592A2 (en)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Oxime/substituted quinoxaline-type piperidine compounds and uses thereof
US9090618B2 (en)	2012-12-27	2015-07-28	Purdue Pharma L.P.	Substituted benzimidazole-type piperidine compounds and uses thereof
WO2014102589A1 (en)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Quinazolin-4(3h)-one-type piperidine compounds and uses thereof
CN111825681A (zh) *	2020-07-07	2020-10-27	扬州大学	一种合成(e)-亚苄基螺吡唑吡咯嗪酮类化合物的方法

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GB157497A (hu) *
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US3318900A (en)	1964-05-06	1967-05-09	Janssen Pharmaceutica Nv	Derivatives of benzimidazolinyl piperidine
US3325499A (en)	1964-11-02	1967-06-13	Mcneilab Inc	1-(1-hydrocarbyl-4-piperdyl)-2-indolinone
US3923993A (en) *	1973-06-28	1975-12-02	American Home Prod	Process for treating neuroendocrinopathic diseases employing fluspirilene
DE2609645A1 (de)	1976-03-09	1977-09-15	Boehringer Sohn Ingelheim	Aminoalkylheterocyclen
US4329353A (en)	1980-10-22	1982-05-11	Janssen Pharmaceutica, N.V.	1-(4-Aryl-cyclohexyl)piperidine derivatives, method of use thereof and pharmaceutical compositions thereof
US4410528A (en)	1980-05-16	1983-10-18	Kyowa Hakko Kogyo Co., Ltd.	Hypotensive piperidine derivatives
JPS58180481A (ja)	1982-04-15	1983-10-21	Kyowa Hakko Kogyo Co Ltd	新規なピペリジン誘導体
JPS60120872A (ja)	1983-12-01	1985-06-28	Kyowa Hakko Kogyo Co Ltd	新規なヘテロ環状化合物及び強心剤
CA2187767A1 (en)	1994-04-14	1995-10-26	Joel R. Huff	Alpha1c adrenergic receptor antagonists
FR2722190B1 (fr)	1994-07-05	1996-10-04	Sanofi Sa	Derives de 1-benzyl-1,3-dihydro-2h-benzimidazol-2-one, leur preparation, les compositions pharmaceutique en contenant
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US5574044A (en)	1994-10-27	1996-11-12	Merck & Co., Inc.	Muscarine antagonists
ATE218126T1 (de)	1995-09-13	2002-06-15	Kyowa Hakko Kogyo Kk	Phenylpiperidin-derivate
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DE69826278T2 (de)	1997-05-30	2005-11-10	Banyu Pharmaceutical Co., Ltd.	2-oxoimidazol-derivate
JPH10330377A (ja)	1997-06-02	1998-12-15	Kyowa Hakko Kogyo Co Ltd	ピペリジン誘導体
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SI0921125T1 (en)	1997-12-05	2002-04-30	F. Hoffmann-La Roche Ag	1,3,8-Triazaspiro(4,5)decan-4-on derivatives
US6166209A (en)	1997-12-11	2000-12-26	Hoffmann-La Roche Inc.	Piperidine derivatives
ES2175925T3 (es)	1998-01-19	2002-11-16	Pfizer	Compuestos 4-(2-ceto-1-benzilimidazolinil)piperidina como agonistas del receptor orl1.
US6410561B1 (en)	1998-03-26	2002-06-25	Japan Tobacco Inc.	Amide derivatives and nociceptin antagonists
EP1080091A1 (en)	1998-05-18	2001-03-07	Novo Nordisk A/S	Novel 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes
ID29137A (id)	1998-07-27	2001-08-02	Schering Corp	Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
US6262066B1 (en)	1998-07-27	2001-07-17	Schering Corporation	High affinity ligands for nociceptin receptor ORL-1
MA26659A1 (fr)	1998-08-06	2004-12-20	Pfizer	Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation.
SE9904652D0 (sv)	1999-12-17	1999-12-17	Astra Pharma Prod	Novel Compounds
CA2421493A1 (en)	2000-09-06	2002-03-14	Ortho-Mcneil Pharmaceutical, Inc.	A method for treating allergies using substituted pyrazoles
HUP0401333A3 (en) *	2001-04-18	2004-11-29	Euro Celtique Sa	Spiropyrazole compounds and pharmaceutical compositions containing them

2002
- 2002-04-18 HU HU0401333A patent/HUP0401333A3/hu unknown
- 2002-04-18 EP EP02739163A patent/EP1385515B1/en not_active Expired - Lifetime
- 2002-04-18 AU AU2002311833A patent/AU2002311833B2/en not_active Ceased
- 2002-04-18 MX MXPA03009604A patent/MXPA03009604A/es active IP Right Grant
- 2002-04-18 IL IL15848502A patent/IL158485A0/xx unknown
- 2002-04-18 PL PL02367263A patent/PL367263A1/xx not_active Application Discontinuation
- 2002-04-18 CN CNA028121767A patent/CN1516584A/zh active Pending
- 2002-04-18 WO PCT/US2002/012376 patent/WO2002085355A1/en not_active Application Discontinuation
- 2002-04-18 KR KR1020037013821A patent/KR100628292B1/ko not_active IP Right Cessation
- 2002-04-18 AT AT02739163T patent/ATE403429T1/de active
- 2002-04-18 RU RU2003133455/04A patent/RU2299883C2/ru not_active IP Right Cessation
- 2002-04-18 DK DK02739163T patent/DK1385515T3/da active
- 2002-04-18 YU YU82403A patent/YU82403A/sh unknown
- 2002-04-18 DE DE60228071T patent/DE60228071D1/de not_active Expired - Lifetime
- 2002-04-18 ES ES02739163T patent/ES2312584T3/es not_active Expired - Lifetime
- 2002-04-18 CZ CZ20032849A patent/CZ20032849A3/cs unknown
- 2002-04-18 CA CA2444634A patent/CA2444634C/en not_active Expired - Fee Related
- 2002-04-18 US US10/126,506 patent/US6635653B2/en not_active Expired - Lifetime
- 2002-04-18 UA UA20031110381A patent/UA74439C2/uk unknown
- 2002-04-18 PT PT02739163T patent/PT1385515E/pt unknown
- 2002-04-18 SI SI200230748T patent/SI1385515T1/sl unknown
- 2002-04-18 NZ NZ528978A patent/NZ528978A/en not_active IP Right Cessation
- 2002-04-18 JP JP2002582928A patent/JP4342181B2/ja not_active Expired - Fee Related
- 2002-04-18 BR BRPI0209127-5A patent/BR0209127A/pt not_active Application Discontinuation
2003
- 2003-06-19 US US10/601,174 patent/US20040087641A1/en not_active Abandoned
- 2003-10-17 ZA ZA200308103A patent/ZA200308103B/en unknown
- 2003-10-17 NO NO20034660A patent/NO20034660L/no not_active Application Discontinuation
- 2003-10-19 IL IL158485A patent/IL158485A/en not_active IP Right Cessation
2004
- 2004-08-03 HK HK04105726.6A patent/HK1062885A1/xx not_active IP Right Cessation
2008
- 2008-10-27 CY CY20081101206T patent/CY1108454T1/el unknown

Also Published As

Publication number	Publication date
WO2002085355A1 (en)	2002-10-31
NZ528978A (en)	2004-06-25
UA74439C2 (uk)	2005-12-15
DK1385515T3 (da)	2008-10-27
CA2444634C (en)	2011-06-07
CA2444634A1 (en)	2002-10-31
PT1385515E (pt)	2008-09-15
CZ20032849A3 (en)	2004-03-17
NO20034660D0 (no)	2003-10-17
ES2312584T3 (es)	2009-03-01
AU2002311833B2 (en)	2005-04-28
MXPA03009604A (es)	2004-04-02
HUP0401333A2 (hu)	2004-10-28
RU2003133455A (ru)	2005-05-10
IL158485A0 (en)	2004-05-12
PL367263A1 (en)	2005-02-21
US20030027834A1 (en)	2003-02-06
KR20040008159A (ko)	2004-01-28
CY1108454T1 (el)	2014-04-09
IL158485A (en)	2009-09-01
EP1385515B1 (en)	2008-08-06
EP1385515A1 (en)	2004-02-04
US20040087641A1 (en)	2004-05-06
HK1062885A1 (en)	2004-12-03
RU2299883C2 (ru)	2007-05-27
NO20034660L (no)	2003-12-17
JP2004531531A (ja)	2004-10-14
DE60228071D1 (de)	2008-09-18
CN1516584A (zh)	2004-07-28
ATE403429T1 (de)	2008-08-15
KR100628292B1 (ko)	2006-09-27
BR0209127A (pt)	2006-03-21
YU82403A (sh)	2006-08-17
JP4342181B2 (ja)	2009-10-14
US6635653B2 (en)	2003-10-21
SI1385515T1 (sl)	2008-12-31
ZA200308103B (en)	2004-10-18
EP1385515A4 (en)	2004-06-30

Legal Events

Date

Code

Title

Description

2008-01-28

HC9A

Change of name, address

Owner name: EURO-CELTIQUE S.A., LU

Free format text: FORMER OWNER(S): EURO-CELTIQUE, S.A., LU

2008-12-29

FD9A

Lapse of provisional protection due to non-payment of fees

Publication	Publication Date	Title
HUP0401333A3 (en)	2004-11-29	Spiropyrazole compounds and pharmaceutical compositions containing them
HUP0400974A3 (en)	2012-09-28	Peptide-based compounds and pharmaceutical compositions containing them
SI1381346T1 (sl)	2016-03-31	Farmacevtski sestavki, ki vsebujejo formoterol
HUP0303325A3 (en)	2008-03-28	Pharmaceutical salts and pharmaceutical compositions containing them
EP1450824A4 (en)	2005-09-28	PHARMACEUTICAL COMPOSITION
IL161616A0 (en)	2004-09-27	Indazolypyrrolotriazine derivatives and pharmaceutical compositions containing the same
HK1072200A1 (en)	2005-08-19	Pro-micelle pharmaceutical compositions
IL162581A0 (en)	2005-11-20	Pharmaceutical compositions containing corticosteroids
IL158044A0 (en)	2004-03-28	Cyclopropylindole derivatives and pharmaceutical compositions containing the same
IL158300A0 (en)	2004-05-12	Bisarylimidazol derivatives and pharmaceutical compositions containing the same
GB0111597D0 (en)	2001-07-04	Pharmaceutical compositions
IL156812A0 (en)	2004-02-08	Phthalazinone-piperidino derivatives and pharmaceutical compositions containing the same
HUP0303163A3 (en)	2008-03-28	Tramadol-based pharmaceutical composition
GB0117057D0 (en)	2001-09-05	Pharmaceutical composition
IL158671A0 (en)	2004-05-12	Benzyloxy derivatives and pharmaceutical compositions containing the same
HUP0400077A2 (hu)	2004-04-28	Deutériumozott 3-piperidino-propiofenon és a vegyületeket tartalmazó gyógyszerekészítmények
EP1408896A4 (en)	2010-02-24	PHARMACEUTICAL COMPOSITION
GB0129117D0 (en)	2002-01-23	Pharmaceutical composition
HUP0401733A3 (en)	2009-06-29	Cyclic amine-derivatives and pharmaceutical compositions containing them
GB0116107D0 (en)	2001-08-22	Pharmaceutical composition
GB0127805D0 (en)	2002-01-09	Pharmaceutical composition
GB0104752D0 (en)	2001-04-18	Pharmaceutical compositions
HUP0301582A3 (en)	2006-04-28	Calcilytic compounds and pharmaceutical compositions containing them
HUP0402600A3 (en)	2011-05-30	D-proline derivatives and pharmaceutical compositions containing them
PL370037A1 (en)	2005-05-16	Pharmaceutical composition