HUP0303022A2 - Kinazolin-ditozilátsó vegyületek, eljárás az előállításukra, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények - Google Patents

Kinazolin-ditozilátsó vegyületek, eljárás az előállításukra, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0303022A2
HUP0303022A2 HU0303022A HUP0303022A HUP0303022A2 HU P0303022 A2 HUP0303022 A2 HU P0303022A2 HU 0303022 A HU0303022 A HU 0303022A HU P0303022 A HUP0303022 A HU P0303022A HU P0303022 A2 HUP0303022 A2 HU P0303022A2
Authority
HU
Hungary
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
salt compounds
ditosylate salt
Prior art date
Application number
HU0303022A
Other languages
English (en)
Inventor
Michael Scott Mcclure
Martin Howard Osterhout
Frank Roschangar
Mark Joseph Sacchetti
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26910112&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0303022(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of HUP0303022A2 publication Critical patent/HUP0303022A2/hu
Publication of HUP0303022A3 publication Critical patent/HUP0303022A3/hu
Publication of HU229624B1 publication Critical patent/HU229624B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

Az (I) általános képletű vegyületek - a képletben R1 jelentése Cl vagyBr; X jelentése CH, N vagy CF; és Het jelentése tiazol- vagyfurángyűrű - és anhidrát és hidrát formáik olyan rendellenességekkezelésére alkalmazhatók, amelyekre az erbB családba tartozó PTK-kabnormális aktivitása jellemző. A találmány tárgyát képezik a fentivegyületeket tartalmazó gyógyászati készítmények, és a fentivegyületek alkalmazása is a fenti célra. Ó
HU0303022A 2000-06-30 2001-06-28 Quinazoline ditosylate salt compounds HU229624B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21550800P 2000-06-30 2000-06-30
US27184501P 2001-02-27 2001-02-27
PCT/US2001/020706 WO2002002552A1 (en) 2000-06-30 2001-06-28 Quinazoline ditosylate salt compounds

Publications (3)

Publication Number Publication Date
HUP0303022A2 true HUP0303022A2 (hu) 2003-12-29
HUP0303022A3 HUP0303022A3 (en) 2009-03-30
HU229624B1 HU229624B1 (en) 2014-03-28

Family

ID=26910112

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303022A HU229624B1 (en) 2000-06-30 2001-06-28 Quinazoline ditosylate salt compounds

Country Status (26)

Country Link
US (2) US7157466B2 (hu)
EP (1) EP1294715B1 (hu)
JP (2) JP4102185B2 (hu)
KR (2) KR100815681B1 (hu)
CN (2) CN1305872C (hu)
AR (1) AR031248A1 (hu)
AT (1) ATE353891T1 (hu)
AU (3) AU2001273071B2 (hu)
BR (1) BR0111947A (hu)
CA (1) CA2413134C (hu)
CY (1) CY1107054T1 (hu)
CZ (2) CZ299561B6 (hu)
DE (1) DE60126611T2 (hu)
DK (1) DK1294715T3 (hu)
ES (1) ES2280382T3 (hu)
HK (1) HK1051041A1 (hu)
HU (1) HU229624B1 (hu)
IL (3) IL153111A0 (hu)
MX (1) MXPA02012681A (hu)
MY (1) MY133667A (hu)
NO (2) NO324637B1 (hu)
NZ (1) NZ522989A (hu)
PL (1) PL204958B1 (hu)
PT (1) PT1294715E (hu)
TW (2) TWI307339B (hu)
WO (1) WO2002002552A1 (hu)

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