HRP20090228T1 - Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions - Google Patents

Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions

Info

Publication number
HRP20090228T1
HRP20090228T1 HR20090228T HRP20090228T HRP20090228T1 HR P20090228 T1 HRP20090228 T1 HR P20090228T1 HR 20090228 T HR20090228 T HR 20090228T HR P20090228 T HRP20090228 T HR P20090228T HR P20090228 T1 HRP20090228 T1 HR P20090228T1
Authority
HR
Croatia
Prior art keywords
regions
complementarity determining
binding properties
immunoglobulin domains
molecule different
Prior art date
Application number
HR20090228T
Other languages
English (en)
Croatian (hr)
Inventor
Wozniak-Knopp Gordana
R�ker Florian
Himmler Gottfried
Original Assignee
F-Star Biotechnologische Forschungs- Und Entwicklungsges.M.B.H.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F-Star Biotechnologische Forschungs- Und Entwicklungsges.M.B.H. filed Critical F-Star Biotechnologische Forschungs- Und Entwicklungsges.M.B.H.
Publication of HRP20090228T1 publication Critical patent/HRP20090228T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/522—CH1 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
HR20090228T 2005-01-05 2009-04-20 Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions HRP20090228T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64114405P 2005-01-05 2005-01-05

Publications (1)

Publication Number Publication Date
HRP20090228T1 true HRP20090228T1 (en) 2009-05-31

Family

ID=36445146

Family Applications (3)

Application Number Title Priority Date Filing Date
HR20090087T HRP20090087T3 (en) 2005-01-05 2009-02-12 Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
HR20090228T HRP20090228T1 (en) 2005-01-05 2009-04-20 Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
HR20090326T HRP20090326T1 (en) 2005-01-05 2009-06-02 Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HR20090087T HRP20090087T3 (en) 2005-01-05 2009-02-12 Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions

Family Applications After (1)

Application Number Title Priority Date Filing Date
HR20090326T HRP20090326T1 (en) 2005-01-05 2009-06-02 Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions

Country Status (23)

Country Link
US (8) US20090298195A1 (xx)
EP (4) EP1772465B1 (xx)
JP (3) JP4937138B2 (xx)
KR (2) KR20130105885A (xx)
CN (2) CN101098891B (xx)
AT (4) ATE423140T1 (xx)
AU (1) AU2006204459B2 (xx)
BR (1) BRPI0606399A8 (xx)
CA (1) CA2594356C (xx)
CY (3) CY1108767T1 (xx)
DE (3) DE602006003695D1 (xx)
DK (4) DK1699826T3 (xx)
EA (1) EA018897B1 (xx)
ES (4) ES2384039T3 (xx)
HR (3) HRP20090087T3 (xx)
IL (1) IL184103A (xx)
MX (1) MX2007008118A (xx)
NZ (1) NZ555893A (xx)
PL (3) PL1699826T3 (xx)
PT (4) PT1772465E (xx)
RS (3) RS50785B (xx)
SI (3) SI1752471T1 (xx)
WO (1) WO2006072620A1 (xx)

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